Falcons vs Panthers Prediction, Picks & Odds | 21 Sep 2025

NFL Betting Preview: Falcons vs Panthers

The Atlanta Falcons battle the Carolina Panthers in this NFL Week 3 matchup at Bank of America Stadium, with kickoff scheduled for 13:00 on Sunday, September 21. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

The total line of 43.5 points looks pretty low and we can take advantage by backing the Overs at -115. We can see the Panthers and the Falcons combining to go bigger.

Riding with our Totals pick? Read our in-depth BetMGM review and grab the latest promo code before you place your bet.

Atlanta Falcons triumphed in their previous game. It was on the road where Minnesota Vikings were beaten 22-6 at US Bank Stadium. The Falcons put up 326 yards, split between 108 passing and 218 rushing yards. They picked up 19 first downs and scored one touchdown.

Carolina Panthers lost on the road in their last game, making it back-to-back defeats. Arizona Cardinals won 27-22 at State Farm Stadium. The Panthers finished with 352 yards, including 303 passing and 49 rushing yards. They managed 26 first downs and reached the end zone 3 times, all via the pass.

Head-to-Head Statistics

The scoreline was 44-38 (OT) in favor of the Panthers when they last played the Falcons, with the matchup taking place at Mercedes-Benz Stadium. The H2H over the past 10 games have seen five wins for both teams.

Quarterbacks

Michael Penix Jr.

214.5 Passing Yards

Over -112

Under -112

Bryce Young

207.5 Passing Yards

Over -112

Under -112

Falcons vs Panthers Prediction & Picks

We cover the essential Falcons vs Panthers betting angles, featuring our main match prediction, correct score pick, top player prop plays and a carefully crafted bet builder.

Game Prediction

We’re confident that Over 43.5 is the value play at -115. We’re expecting these NFL rivals to rack up the points, so a total bet could be the way forward.

Injuries are always factored in by the NFL handicappers at Sportsgambler.com. Our picks are also shaped by recent form, with up-to-date stats playing a key role before any selections are locked in.

Key Falcons vs Panthers stats:

• The 43.5 line has been covered in 6 of the last 10 Falcons games on the road.
• The 43.5 line has been covered in 3 of the last 5 Falcons games on the road.
• The 43.5 line has been covered in the last 4 Panthers games at home.
• The 43.5 line has been covered in 7 of the last 10 Panthers games.
• The 43.5 line has been covered in 14 of the last 20 Panthers games.
• The 43.5 line has been covered in the last 2 games between these teams.

Over 43.5 Probability

The best betting apps make it a 53.5% chance that our pick is settled as a winner. In our opinion, there’s actually a probability of success closer to 60%. It’s why we think it’s worth placing this wager.

Looking for a bigger return on your Total bet? Consider the Result & Total lines where you combine the winning franchise and Over a certain number of points.

Our easy-to-use guide showcases the best betting offers available now, complete with free bets and the latest bonus deals.

Our Game Prediction

Over 43.5 Points @ -115 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (19:26, 19 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Drake London Anytime TD +150

Drake London (Falcons) can be backed at +150 to score a TD. We’ll have a play on this Anytime Touchdown Scorer bet, which could hopefully result in him taking it to the house.

Latest Drake London Player Prop Odds

Touchdown

Anytime

+155

First

+900

Receiving Yards

Over 64.5

-112

Under 64.5

-112

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Tetairoa McMillan Over 65.5 Receiving Yards -114

You can place a bet on Tetairoa McMillan (Panthers) at -114 to exceed 65.5 receiving yards. We’re happy to take him to cover the Player Receiving Yards line and bettors can place this wager with confidence.

Latest Tetairoa McMillan Player Prop Odds

Touchdown

Anytime

+195

First

+1200

Receiving Yards

Over 65.5

-112

Under 65.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Falcons 30 - 23 Panthers

There are a range of correct score lines to choose from and we’re taking a chance on the Falcons to record a 30-23 victory. There’s a massive return if we get this right.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Falcons vs Panthers Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Atlanta Falcons have the shortest price to win this game, with the sportsbooks giving them a 70% probability due to their -233 Moneyline betting odds. The market suggests that Carolina Panthers are least likely to win at +190.

The current spread is 4.5 and total points is 43.5. A Total bet is always available and can often provide value selections. The Over 43.5 selection is available to back at -115.

You’ll find a huge variety of game lines and team props for every matchup. The top NFL sportsbooks provide an impressive mix of pre-game and in-game options to suit your betting style.

Moneyline

Falcons

-233

Panthers

+190

Point Spread

Falcons -4.5

-110

Panthers +4.5

-110

Total Points

Under 43.5

-105

Over 43.5

-115

Bijan Robinson is the favorite to be First Touchdown Scorer at +300. If you’re interested in backing him to score a TD at anytime, then the price is -233.

Touchdown

Bijan Robinson (Falcons)

First TD

+300

Anytime TD

-233

Chuba Hubbard (Panthers)

First TD

+550

Anytime TD

-120

Drake London (Falcons)

First TD

+900

Anytime TD

+155

Tyler Allgeier (Falcons)

First TD

+1100

Anytime TD

+240

Tetairoa McMillan (Panthers)

First TD

+1200

Anytime TD

+195

Darnell Mooney (Falcons)

First TD

+1300

Anytime TD

+280

Kyle Pitts (Falcons)

First TD

+1500

Anytime TD

+310

Hunter Renfrow (Panthers)

First TD

+2000

Anytime TD

+370

Rico Dowdle (Panthers)

First TD

+2000

Anytime TD

+400

Ray-Ray McCloud III (Falcons)

First TD

+2000

Anytime TD

+430

Xavier Legette (Panthers)

First TD

+2500

Anytime TD

+430

Ja'Tavion Sanders (Panthers)

First TD

+2500

Anytime TD

+460

Michael Penix Jr. (Falcons)

First TD

+2500

Anytime TD

+550

Bryce Young (Panthers)

First TD

+2700

Anytime TD

+600

Tommy Tremble (Panthers)

First TD

+4500

Anytime TD

+1000

Casey Washington (Falcons)

First TD

+5000

Anytime TD

+1300

KhaDarel Hodge (Falcons)

First TD

+5000

Anytime TD

+1300

David Sills V (Falcons)

First TD

+5000

Anytime TD

+1300

Charlie Woerner (Falcons)

First TD

+7500

Anytime TD

+1700

Teagan Quitoriano (Falcons)

First TD

+8000

Anytime TD

+2500

Brycen Tremayne (Panthers)

First TD

+8000

Anytime TD

+1800

Mitchell Evans (Panthers)

First TD

+10000

Anytime TD

+2500

Trevor Etienne (Panthers)

First TD

+10000

Anytime TD

+1900

Nathan Carter (Falcons)

First TD

+10000

Anytime TD

+2500

David Moore (Panthers)

First TD

+10000

Anytime TD

+3000

Feleipe Franks (Falcons)

First TD

+10000

Anytime TD

+4500

Jimmy Horn Jr. (Panthers)

First TD

+10000

Anytime TD

+3000

Dalevon Campbell (Panthers)

First TD

+10000

Anytime TD

+3000

James Mitchell (Panthers)

First TD

+10000

Anytime TD

+2500

Receiving Yards

Tetairoa McMillan (Panthers)

Over 65.5

-112

Under 65.5

-112

Drake London (Falcons)

Over 64.5

-112

Under 64.5

-112

Kyle Pitts (Falcons)

Over 40.5

-112

Under 40.5

-112

Darnell Mooney (Falcons)

Over 39.5

-112

Under 39.5

-112

Hunter Renfrow (Panthers)

Over 31.5

-112

Under 31.5

-112

Bijan Robinson (Falcons)

Over 24.5

-112

Under 24.5

-112

Xavier Legette (Panthers)

Over 24.5

-112

Under 24.5

-112

Ja'Tavion Sanders (Panthers)

Over 23.5

-112

Under 23.5

-112

Chuba Hubbard (Panthers)

Over 16.5

-112

Under 16.5

-112

Rushing Yards

Bijan Robinson (Falcons)

Over 81.5

-112

Under 81.5

-112

Chuba Hubbard (Panthers)

Over 54.5

-112

Under 54.5

-112

Tyler Allgeier (Falcons)

Over 43.5

-112

Under 43.5

-112

Rico Dowdle (Panthers)

Over 16.5

-112

Under 16.5

-112

Bryce Young (Panthers)

Over 13.5

-112

Under 13.5

-112

Michael Penix Jr. (Falcons)

Over 5.5

-112

Under 5.5

-112

Passing Yards

Michael Penix Jr. (Falcons)

Over 214.5

-112

Under 214.5

-112

Bryce Young (Panthers)

Over 207.5

-112

Under 207.5

-112

An increasing number of bettors are now enjoying micro betting on the NFL and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Panthers Record Shows Eight Losses From Last Ten Home Games

The Panthers have a 2-8 record in their last 10 home games, scoring 20.00 points per contest and conceding 27.80.

The Falcons are 5-5 in their last 10 road games, averaging 21.30 points scored and 26.00 points allowed.

The Falcons earned a 38-20 win over the Panthers the last time they played at Bank of America Stadium. From the past 6 head-to-heads at Bank of America Stadium, the Falcons have won four while the Panthers have taken two.

Last 10 Games		W-L	P	PF	PA	O43.5	U43.5
Panthers Home Stats		2-8	47.80	20.00	27.80	8	2
Falcons Away Stats		5-5	47.30	21.30	26.00	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O43.5 = Games Over 43.5 Points
• U43.5 = Games Under 43.5 Points

Latest regular season and playoff games stats.

Atlanta Falcons Stats

Carolina Panthers Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• -5.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -5.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• +5.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +5.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 44.60 pts in the previous 10 games
• Game Totals on the Road: An average of 47.30 pts in the previous 10 games on the road
• Over 43.5: Covered in 4 of the previous 10 games
• Over 43.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 21.00 pts and allowed 23.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 21.30 pts and allowed 26.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 52.00 pts in the previous 10 games
• Game Totals at Home: An average of 45.20 pts in the previous 10 home games
• Over 43.5: Covered in 7 of the previous 10 games
• Over 43.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 22.60 pts and allowed 29.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 19.00 pts and allowed 26.20 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 369.50 Yds. Allowed 316.30 Yds
• Rushing Yards: Gained 144.00 Yds. Allowed 103.20 Yds
• Passing Yards: Gained 225.00 Yds. Allowed 213.10 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 1.40 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 0.50 TD. Allowed 2.20 TD
• Total 1st Downs: Picked up 21.90. Allowed 17.90
• Total Turnovers: Committed 1.40. Committed by opponents 1.20
• Total Penalties: Committed 5.90. Committed by opponents 7.00
• Penalty Yards: Lost 45.80 Yds. Gained 57.70 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 312.00 Yds. Allowed 402.00 Yds
• Rushing Yards: Gained 107.20 Yds. Allowed 188.80 Yds
• Passing Yards: Gained 204.80 Yds. Allowed 213.20 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 3.20 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.90 TD
• Total 1st Downs: Picked up 19.00. Allowed 24.20
• Total Turnovers: Committed 1.20. Committed by opponents 1.10
• Total Penalties: Committed 6.70. Committed by opponents 8.50
• Penalty Yards: Lost 55.20 Yds. Gained 65.60 Yds

Last 10 Games on the Road

• Total Yards: Gained 371.00 Yds. Allowed 358.90 Yds
• Rushing Yards: Gained 145.80 Yds. Allowed 123.10 Yds
• Passing Yards: Gained 224.70 Yds. Allowed 235.80 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 3.10 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.10 TD. Allowed 2.50 TD
• Total 1st Downs: Picked up 20.00. Allowed 20.80
• Total Turnovers: Committed 1.20. Committed by opponents 1.40
• Total Penalties: Committed 5.90. Committed by opponents 7.40
• Penalty Yards: Lost 51.10 Yds. Gained 55.60 Yds

Last 10 Home Games

• Total Yards: Gained 289.60 Yds. Allowed 376.70 Yds
• Rushing Yards: Gained 116.80 Yds. Allowed 183.60 Yds
• Passing Yards: Gained 172.80 Yds. Allowed 193.10 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.10 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 16.90. Allowed 23.40
• Total Turnovers: Committed 1.30. Committed by opponents 1.20
• Total Penalties: Committed 7.70. Committed by opponents 6.90
• Penalty Yards: Lost 60.70 Yds. Gained 55.50 Yds

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