Falcons vs 49ers Prediction, Picks & Odds | 19 Oct 2025

NFL Betting Preview: Falcons vs Niners

The Atlanta Falcons square off against the San Francisco 49ers in this NFL Week 7 clash at Levi's Stadium, with kickoff scheduled for 20:20 on Sunday, October 19. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

The Unders looks the way to go when the Niners meet the Falcons. The line looks too high at 46.5 and odds of -104 could favor bettors who go below that total.

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Atlanta Falcons claimed a home victory in their previous game. A 24-14 triumph against Buffalo Bills at Mercedes-Benz Stadium made it back-to-back wins. The Falcons put up 443 yards, split between 233 passing and 210 rushing yards. The offense converted for 22 first downs along with 3 touchdowns.

San Francisco 49ers were defeated in their last game. On the road, they suffered a 30-19 reverse against Tampa Bay Buccaneers at Raymond James Stadium. The 49ers generated 363 total yards, made up of 296 passing and 67 rushing yards. The offense picked up 17 first downs and reached the end zone once.

Head-to-Head Statistics

The scoreline was 28-14 in favor of the Falcons when they last played the Niners, with the matchup taking place at Mercedes-Benz Stadium. We’ve seen two Falcons wins in the past 3 meetings between the teams.

Quarterbacks

Michael Penix Jr.

221.5 Passing Yards

Over -112

Under -112

Mac Jones

241.5 Passing Yards

Over -112

Under -112

Falcons vs 49ers Prediction & Picks

Step into Falcons vs 49ers with confidence, armed with our expert match prediction, likely scoreline, key player prop plays and a custom-built bet builder for maximum value.

Game Prediction

The totals for this NFL battle provides plenty of value at -104. The betting line is set at 46.5 and we’d be surprised if the combined points total exceeds that amount.

Getting the lowdown on injuries and analyzing the form guide are key steps before making NFL picks. We also put strong emphasis on stats, where a data-led approach often leads to smarter predictions.

Key Falcons vs 49ers stats:

• The 46.5 line hasn’t been covered in 4 of the last 5 Falcons games this season.
• The 46.5 line hasn’t been covered in 6 of the last 10 Falcons games.
• The 46.5 line hasn’t been covered in the last 2 Falcons games on the road.
• The 46.5 line hasn’t been covered in the last 2 games between these teams.

Under 46.5 Probability

Based on the odds from the top NFL betting sites, there’s a 51% likelihood of our pick delivering a return. Our cappers think there’s a stronger chance of success and calculate the probability to be closer to 60%. That means we’re regarding it as a value bet.

If you’re wanting bigger odds for your Under bet, then there’s a way of changing the line and shooting for a lower points total in the hope of a better return.

Getting ready to place a wager? Check our updated guide for the latest betting offers, including free bets and the newest promos codes.

Our Game Prediction

Under 46.5 Points @ -104 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (02:26, 18 October 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Kendrick Bourne Anytime TD +180

Kendrick Bourne (Niners) can be backed at +180 to hit the end zone. It’s worth a gamble on him to be Anytime Touchdown Scorer as there’s plenty of juice in these betting odds.

Latest Kendrick Bourne Player Prop Odds

Touchdown

Anytime

+200

First

+1200

Receiving Yards

Over 48.5

-112

Under 48.5

-112

---

Michael Penix Jr. Under 219.5 Passing Yards -114

You can place a bet on Michael Penix Jr. (Falcons) at -114 to record fewer than 219.5 passing yards. It’s reasonable to expect he may fall short, making the QB Passing Yards line appealing.

Latest Michael Penix Jr. Player Prop Odds

Touchdown

Anytime

+750

First

+3500

Passing Yards

Over 221.5

-112

Under 221.5

-112

Rushing Yards

Over 5.5

-112

Under 5.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Falcons 21 - 17 49ers

For a fun wager, consider backing the Falcons to claim a 21-17 victory. Although it’s a speculative bet, we are expecting things to be close between the two teams.

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Falcons vs 49ers Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

There are betting odds of -263 that San Francisco 49ers land victory, with Atlanta Falcons alternatively at +215. If you want to know the probability of the road team winning this game, it’s 32% according to the most popular sportsbooks.

The spread is 6.5 and the total points line is currently 47.5. NFL fans regularly enjoy the opportunity to bet on the Totals. Those who wager Under 47.5 can get -115.

Consider every angle when placing your National Football League wagers. The top betting apps have a huge selection of game lines and team props and it’s all about finding a bet which matches your prediction of the game.

Moneyline

Falcons

+215

49ers

-263

Point Spread

Falcons +6.5

-110

49ers -6.5

-110

Total Points

Under 47.5

-115

Over 47.5

-105

Bijan Robinson is priced at +400 when it comes to First TD Scorer. He’s the favorite and also available at odds of -164 to score a touchdown at anytime.

Touchdown

Bijan Robinson (Falcons)

First TD

+400

Anytime TD

-164

Christian McCaffrey (49ers)

First TD

+500

Anytime TD

-149

Drake London (Falcons)

First TD

+850

Anytime TD

+165

Tyler Allgeier (Falcons)

First TD

+1000

Anytime TD

+200

Kendrick Bourne (49ers)

First TD

+1200

Anytime TD

+200

George Kittle (49ers)

First TD

+1200

Anytime TD

+200

Darnell Mooney (Falcons)

First TD

+1400

Anytime TD

+290

Jauan Jennings (49ers)

First TD

+1500

Anytime TD

+250

Kyle Pitts (Falcons)

First TD

+1500

Anytime TD

+290

Jake Tonges (49ers)

First TD

+2500

Anytime TD

+500

Demarcus Robinson (49ers)

First TD

+3000

Anytime TD

+600

Casey Washington (Falcons)

First TD

+3000

Anytime TD

+700

Michael Penix Jr. (Falcons)

First TD

+3500

Anytime TD

+750

Brian Robinson Jr. (49ers)

First TD

+4000

Anytime TD

+650

Kyle Juszczyk (49ers)

First TD

+4500

Anytime TD

+900

Mac Jones (49ers)

First TD

+5000

Anytime TD

+1100

Marquez Valdes-Scantling (49ers)

First TD

+6000

Anytime TD

+1200

Charlie Woerner (Falcons)

First TD

+6000

Anytime TD

+1000

Brayden Willis (49ers)

First TD

+8000

Anytime TD

+1300

David Sills V (Falcons)

First TD

+8000

Anytime TD

+1400

Luke Farrell (49ers)

First TD

+10000

Anytime TD

+1700

KhaDarel Hodge (Falcons)

First TD

+10000

Anytime TD

+2200

Jamal Agnew (Falcons)

First TD

+10000

Anytime TD

+1900

Jordan Watkins (49ers)

First TD

+10000

Anytime TD

+1800

Skyy Moore (49ers)

First TD

+10000

Anytime TD

+1400

Isaac Guerendo (49ers)

First TD

+10000

Anytime TD

+2500

Nathan Carter (Falcons)

First TD

+10000

Anytime TD

+2700

Teagan Quitoriano (Falcons)

First TD

+10000

Anytime TD

+3300

Feleipe Franks (Falcons)

First TD

+10000

Anytime TD

+4000

Receiving Yards

Drake London (Falcons)

Over 71.5

-112

Under 71.5

-112

George Kittle (49ers)

Over 53.5

-112

Under 53.5

-112

Kendrick Bourne (49ers)

Over 48.5

-112

Under 48.5

-112

Christian McCaffrey (49ers)

Over 45.5

-112

Under 45.5

-112

Bijan Robinson (Falcons)

Over 39.5

-112

Under 39.5

-112

Kyle Pitts (Falcons)

Over 37.5

-112

Under 37.5

-112

Darnell Mooney (Falcons)

Over 35.5

-112

Under 35.5

-112

Jauan Jennings (49ers)

Over 35.5

-112

Under 35.5

-112

Demarcus Robinson (49ers)

Over 16.5

-112

Under 16.5

-112

Jake Tonges (49ers)

Over 9.5

-112

Under 9.5

-112

Kyle Juszczyk (49ers)

Over 5.5

-112

Under 5.5

-112

Rushing Yards

Bijan Robinson (Falcons)

Over 75.5

-112

Under 75.5

-112

Christian McCaffrey (49ers)

Over 64.5

-112

Under 64.5

-112

Tyler Allgeier (Falcons)

Over 32.5

-112

Under 32.5

-112

Brian Robinson Jr. (49ers)

Over 12.5

-112

Under 12.5

-112

Michael Penix Jr. (Falcons)

Over 5.5

-112

Under 5.5

-112

Mac Jones (49ers)

Over 5.5

-116

Under 5.5

-110

Passing Yards

Mac Jones (49ers)

Over 241.5

-112

Under 241.5

-112

Michael Penix Jr. (Falcons)

Over 221.5

-112

Under 221.5

-112

You don’t have to wait for the final outcome when it comes to NFL micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Niners Stand on Six Losses From Past Ten Home Games

The Niners own a 4-6 mark in their past 10 home games, averaging 23.30 points scored and 21.50 points allowed.

The Falcons own a 5-5 mark in their past 10 games away from home, putting up 19.60 points per contest and giving up 24.20.

The Niners defeated the Falcons 31-13 when the teams last met at Levi's Stadium.

Last 10 Games		W-L	P	PF	PA	O46.5	U46.5
49ers Home Stats		4-6	44.80	23.30	21.50	5	5
Falcons Away Stats		5-5	43.80	19.60	24.20	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O46.5 = Games Over 46.5 Points
• U46.5 = Games Under 46.5 Points

Latest regular season and playoff games stats.

Atlanta Falcons Stats

San Francisco 49ers Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• +1.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +1.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -1.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -1.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 46.40 pts in the previous 10 games
• Game Totals on the Road: An average of 43.80 pts in the previous 10 games on the road
• Over 46.5: Covered in 4 of the previous 10 games
• Over 46.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.20 pts and allowed 23.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 19.60 pts and allowed 24.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 46.20 pts in the previous 10 games
• Game Totals at Home: An average of 44.80 pts in the previous 10 home games
• Over 46.5: Covered in 6 of the previous 10 games
• Over 46.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 20.60 pts and allowed 25.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 23.30 pts and allowed 21.50 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 385.60 Yds. Allowed 302.00 Yds
• Rushing Yards: Gained 156.20 Yds. Allowed 116.60 Yds
• Passing Yards: Gained 229.40 Yds. Allowed 185.40 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 1.50 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 0.80 TD. Allowed 2.00 TD
• Total 1st Downs: Picked up 22.00. Allowed 18.20
• Total Turnovers: Committed 1.20. Committed by opponents 1.50
• Total Penalties: Committed 5.90. Committed by opponents 7.10
• Penalty Yards: Lost 45.40 Yds. Gained 59.20 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 371.80 Yds. Allowed 343.70 Yds
• Rushing Yards: Gained 85.00 Yds. Allowed 125.70 Yds
• Passing Yards: Gained 286.80 Yds. Allowed 218.00 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 0.40 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.70 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 21.80. Allowed 20.00
• Total Turnovers: Committed 1.70. Committed by opponents 0.50
• Total Penalties: Committed 7.40. Committed by opponents 5.60
• Penalty Yards: Lost 56.30 Yds. Gained 40.90 Yds

Last 10 Games on the Road

• Total Yards: Gained 365.30 Yds. Allowed 341.30 Yds
• Rushing Yards: Gained 151.10 Yds. Allowed 118.70 Yds
• Passing Yards: Gained 213.70 Yds. Allowed 222.60 Yds
• Total Touchdowns: Scored 1.90 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 0.90 TD. Allowed 2.10 TD
• Total 1st Downs: Picked up 20.30. Allowed 19.60
• Total Turnovers: Committed 1.20. Committed by opponents 1.50
• Total Penalties: Committed 5.40. Committed by opponents 7.70
• Penalty Yards: Lost 45.90 Yds. Gained 59.60 Yds

Last 10 Home Games

• Total Yards: Gained 373.30 Yds. Allowed 297.20 Yds
• Rushing Yards: Gained 118.10 Yds. Allowed 119.50 Yds
• Passing Yards: Gained 255.20 Yds. Allowed 177.70 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 2.30 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 20.30. Allowed 17.50
• Total Turnovers: Committed 1.90. Committed by opponents 1.00
• Total Penalties: Committed 5.90. Committed by opponents 4.80
• Penalty Yards: Lost 44.00 Yds. Gained 37.00 Yds

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