NFL Betting Preview: Panthers vs Jaguars

The Carolina Panthers go up against the Jacksonville Jaguars in this NFL Week 1 matchup at EverBank Stadium, with kickoff scheduled for 13:00 on Sunday 7 September. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Expect Jaguars to Dominate Panthers

Our betting prediction is that the Jaguars are going to cover the -3.5 on the spread. You can get -115 that there’s a bigger margin of victory against the Panthers.

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Jaguars 26-0 Win in Last H2H Matchup

Carolina Panthers won their previous game 44-38. This was a road victory at Mercedes-Benz Stadium against Atlanta Falcons. The Panthers moved the ball for 425 yards, made up of 270 through the air and 155 on the ground. The offense converted for 25 first downs and scored 6 TD's, including 3 passing scores and 3 rushing touchdowns.

Jacksonville Jaguars were beaten last game and this was on the road at Lucas Oil Stadium. Indianapolis Colts claimed a 26-23 win. The Jaguars recorded 319 total yards, made up of 206 through the air and 113 on the ground. The offense managed 19 first downs and scored 2 touchdowns, one on the ground and one through the air.

Head-to-Head Statistics

The last matchup between the Jaguars and the Panthers saw the former win. It was a 26-0 scoreline at EverBank Stadium.

Quarterbacks

Bryce Young

Trevor Lawrence

Panthers vs Jaguars Prediction & Picks

Our Panthers vs Jaguars tips include the main match prediction, a correct score forecast, bet builder advice and top player prop picks. Each section below offers expert insight into the key betting angles.

Game Prediction

There’s a generous line of -3.5 when it comes to the Jaguars for this NFL showdown. The -115 that they cover the spread has plenty of juice and our pick is that the favorites will make it happen.

The NFL handicappers at Sportsgambler.com start by analyzing recent form and staying on top of injury news before making any predictions. From there, we interpret the story the stats are telling to help shape our picks.

Key Panthers vs Jaguars stats:

The +3.5 line hasn’t been covered by Panthers in 8 of their last 10 games on the road.
The +3.5 line hasn’t been covered by Panthers in 4 of their last 5 games on the road.

Jaguars -3.5 Probability

According to the best NFL sportsbooks, our pick has a 53.5% chance of winning. Based on our cappers in-depth research, we calculate the actual probability to be closer to 60%. This is why we can recommend this bet.

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Best Bet

Jaguars -3.5 @ -115 Watch Live Bet Now

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Published 19:26, 05 September 2025

Player Prop Picks

Top Pick: Trevor Lawrence Over 239.5 Passing Yards -114

Trevor Lawrence (Jaguars) can be backed at -114 to accumulate over 239.5 passing yards. We believe it makes sense to stick with him on the Over and bettors can be confident in this QB Passing Yards pick.

Latest Trevor Lawrence Player Prop Odds

Touchdown

Passing Yards

Rushing Yards

Rico Dowdle Over 24.5 Rushing Yards -114

You can back Rico Dowdle (Panthers) at -114 to accumulate over 24.5 rushing yards. With confidence, we can back him to cover the generous Player Rushing Yards line, as all the signs point to him reaching the expected total.

Latest Rico Dowdle Player Prop Odds

Touchdown

Rushing Yards

Same Game Parlay Picks

Spread Jaguars -3.5

Totals Over 46.5

Passing Yards Trevor Lawrence Over 239.5

We’ve got a same game parlay with three options: Jaguars -3.5, Over 46.5 points and Trevor Lawrence (Jaguars) to have Over 239.5 passing yards.

We recommend a same game parlay as it’s an exciting way of wagering on a single event. Many bettors like to create a personalised football bet which reflects their predictions for how a game is going to play out.

Bet Boosts

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Correct Score Prediction

Panthers

21 - 28 Jaguars logo

Jaguars

For those looking to get more bang for their buck, consider a correct score bet on the Jaguars. Backing them to win 28-21 means you can land a potential monster return.

Panthers vs Jaguars Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Jaguars Trading at Shorter Odds Than Panthers

The Jacksonville Jaguars odds have been priced up by the sportsbooks and they are -196 betting favorites to land victory in this game which means a 66% chance of winning. Carolina Panthers are regarded as a long shot to win and you can currently back them at +164.

The spread is calculated to be 3.5, while total points comes in at 46.5. There are many ways to bet on the NFL including the Totals. If you’re going for Under 46.5, this outcome can be backed at -105.

You can find a huge selection of game lines and team props for every National Football League showdown, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your wagers.

Moneyline

Point Spread

Total Points

Chuba Hubbard Favorite to Score First TD

Favorite Chuba Hubbard is priced at +600 to be the first player to score a touchdown. There’s also the opportunity to back him to score a TD at anytime at odds of -115.

Touchdown

Chuba Hubbard (Panthers)

Tank Bigsby (Jaguars)

Brian Thomas Jr (Jaguars)

Travis Etienne Jr. (Jaguars)

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Receiving Yards

Brian Thomas Jr (Jaguars)

Tetairoa McMillan (Panthers)

Travis Hunter (Jaguars)

Xavier Legette (Panthers)

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Rushing Yards

Chuba Hubbard (Panthers)

Tank Bigsby (Jaguars)

Travis Etienne Jr. (Jaguars)

Rico Dowdle (Panthers)

View More View Less

Passing Yards

Trevor Lawrence (Jaguars)

Bryce Young (Panthers)

Best Betting Offers

EverBank Stadium

Jaguars Have Seven Home Defeats in Previous Ten Matches

The Jaguars own a 3-7 mark in their past 10 home games, scoring 21.30 points per contest and conceding 21.90.

The Panthers own a 2-8 mark in their past 10 games away from home, putting up 15.70 points per contest and giving up 33.50.

The last EverBank Stadium meeting saw the Jaguars beat the Panthers 26-0.

Last 10 Games		W-L	P	PF	PA	O46.5	U46.5
Jaguars Home Stats		3-7	43.20	21.30	21.90	4	6
Panthers Away Stats		2-8	49.20	15.70	33.50	5	5

W-L = Wins-Losses
P = Avg. Points
PF = Avg. Points For
PA = Avg. Points Against
O46.5 = Games Over 46.5 Points
U46.5 = Games Under 46.5 Points

Last 5 & H2H

All
Home
Away

Last 5 Games

Panthers

NFL: 05/01 Panthers44 Falcons 38
NFL: 29/12 Panthers14 Buccaneers 48
NFL: 22/12 Cardinals30 Panthers 36
NFL: 15/12 Cowboys30 Panthers 14
NFL: 08/12 Panthers16 Eagles 22

Jaguars

NFL: 05/01 Jaguars23 Colts 26
NFL: 29/12 Titans13 Jaguars 20
NFL: 22/12 Jaguars14 Raiders 19
NFL: 15/12 Jets32 Jaguars 25
NFL: 08/12 Jaguars10 Titans 6

Head to Head

Panthers vs Jaguars

NFL: 31/12 2023 Panthers 0 Jaguars 26
NFL: 06/10 2019 Jaguars 27 Panthers 34

Team Stats

Latest regular season and playoff games stats.

Carolina Panthers Stats

Jacksonville Jaguars Stats

Moneyline

4 wins and 6 defeats in the last 10 games
2 wins and 8 defeats in the last 10 games on the road

Moneyline

2 wins and 8 defeats in the last 10 games
4 wins and 6 defeats in the last 10 home games

Point Spread

+3.5 Betting Line: Have covered the spread in 6 of the last 10 games
+3.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road

Point Spread

-3.5 Betting Line: Have covered the spread in 2 of the last 10 games
-3.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

Game Totals: An average of 52.20 pts in the previous 10 games
Game Totals on the Road: An average of 49.20 pts in the previous 10 games on the road
Over 46.5: Covered in 5 of the previous 10 games
Over 46.5 on the Road: Covered in 5 of the previous 10 games on the road
Team Totals: Have scored an average of 23.10 pts and allowed 29.10 pts in the last 10 games
Team Totals on the Road: Have scored an average of 15.70 pts and allowed 33.50 pts in the last 10 games on the road

Total Points

Game Totals: An average of 41.60 pts in the previous 10 games
Game Totals at Home: An average of 41.50 pts in the previous 10 home games
Over 46.5: Covered in 5 of the previous 10 games
Over 46.5 at Home: Covered in 4 of the previous 10 home games
Team Totals: Have scored an average of 17.50 pts and allowed 24.10 pts in the last 10 games
Team Totals at Home: Have scored an average of 21.40 pts and allowed 20.10 pts in the last 10 home games

Game Stats

Last 10 Games

Total Yards: Gained 304.30 Yds. Allowed 417.60 Yds
Rushing Yards: Gained 105.90 Yds. Allowed 190.50 Yds
Passing Yards: Gained 198.40 Yds. Allowed 227.10 Yds
Total Touchdowns: Scored 2.80 TD. Allowed 3.40 TD
Rushing Touchdowns: Scored 1.30 TD. Allowed 1.10 TD
Passing Touchdowns: Scored 1.50 TD. Allowed 2.10 TD
Total 1st Downs: Picked up 18.00. Allowed 25.50
Total Turnovers: Committed 1.00. Committed by opponents 1.10
Total Penalties: Committed 7.00. Committed by opponents 7.60
Penalty Yards: Lost 53.80 Yds. Gained 61.90 Yds

Game Stats

Last 10 Games

Total Yards: Gained 292.40 Yds. Allowed 399.40 Yds
Rushing Yards: Gained 85.80 Yds. Allowed 153.60 Yds
Passing Yards: Gained 206.60 Yds. Allowed 245.80 Yds
Total Touchdowns: Scored 1.80 TD. Allowed 2.50 TD
Rushing Touchdowns: Scored 0.70 TD. Allowed 1.20 TD
Passing Touchdowns: Scored 1.00 TD. Allowed 1.30 TD
Total 1st Downs: Picked up 16.70. Allowed 23.60
Total Turnovers: Committed 1.70. Committed by opponents 0.60
Total Penalties: Committed 5.70. Committed by opponents 5.10
Penalty Yards: Lost 48.30 Yds. Gained 38.60 Yds

Last 10 Games on the Road

Total Yards: Gained 274.40 Yds. Allowed 386.10 Yds
Rushing Yards: Gained 104.60 Yds. Allowed 156.90 Yds
Passing Yards: Gained 169.80 Yds. Allowed 229.20 Yds
Total Touchdowns: Scored 1.90 TD. Allowed 4.10 TD
Rushing Touchdowns: Scored 0.80 TD. Allowed 1.50 TD
Passing Touchdowns: Scored 1.10 TD. Allowed 2.30 TD
Total 1st Downs: Picked up 15.60. Allowed 22.70
Total Turnovers: Committed 1.40. Committed by opponents 0.60
Total Penalties: Committed 5.10. Committed by opponents 5.60
Penalty Yards: Lost 41.10 Yds. Gained 47.30 Yds

Last 10 Home Games

Total Yards: Gained 345.60 Yds. Allowed 344.50 Yds
Rushing Yards: Gained 115.60 Yds. Allowed 130.10 Yds
Passing Yards: Gained 230.00 Yds. Allowed 214.40 Yds
Total Touchdowns: Scored 2.20 TD. Allowed 1.90 TD
Rushing Touchdowns: Scored 0.90 TD. Allowed 0.70 TD
Passing Touchdowns: Scored 1.20 TD. Allowed 1.20 TD
Total 1st Downs: Picked up 18.60. Allowed 20.60
Total Turnovers: Committed 1.20. Committed by opponents 0.80
Total Penalties: Committed 5.00. Committed by opponents 5.90
Penalty Yards: Lost 43.30 Yds. Gained 41.80 Yds

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Team News

Carolina Panthers Injuries

Type

Name

Info

Popo Aumavae

Achilles

Jonathon Brooks

Knee - ACL

Jalen Coker

Quadriceps

Ikem Ekwonu

Appendix

Damarri Mathis

Knee

LaBryan Ray

Ankle

Jacksonville Jaguars Injuries

Type

Name

Info

Montaric Brown

Ankle

Joshua Cephus

Undisclosed

Dennis Daley

Undisclosed

Cooper Hodges

Knee

Jalen McLeod

Lower Body

Wyatt Milum

Knee

Caleb Ransaw

Lower Body

Cole Van Lanen

Shoulder

Previous Carolina Panthers Lineups

05 Jan NFL

Panthers 44-38 Falcons

AFC East	PCT	Home	Road	Div	Conf	Last 5	Strk
Bills	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Dolphins	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Patriots	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Jets	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-

AFC North	PCT	Home	Road	Div	Conf	Last 5	Strk
Ravens	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Bengals	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Browns	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Steelers	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-

AFC South	PCT	Home	Road	Div	Conf	Last 5	Strk
Texans	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Colts	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Jaguars	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Titans	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-

AFC West	PCT	Home	Road	Div	Conf	Last 5	Strk
Broncos	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Chiefs	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Raiders	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Chargers	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-

NFC East	W	L	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Eagles	1	0	1.000	24	20	4	1-0-0	0-0-0	1-0-0	1-0-0	1-0-0	1W
Giants	0	0	-	0	0	0	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Commanders	0	0	-	0	0	0	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Cowboys	0	1	0.000	20	24	-4	0-0-0	0-1-0	0-1-0	0-1-0	0-1-0	1L

NFC North	PCT	Home	Road	Div	Conf	Last 5	Strk
Bears	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Lions	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Packers	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Vikings	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-

NFC South	PCT	Home	Road	Div	Conf	Last 5	Strk
Falcons	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Panthers	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Saints	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Buccaneers	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-

NFC West	PCT	Home	Road	Div	Conf	Last 5	Strk
Cardinals	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Rams	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
49ers	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-
Seahawks	-	0-0-0	0-0-0	0-0-0	0-0-0	-	-

NFL Betting Preview: Panthers vs Jaguars

Head-to-Head Statistics

Panthers vs Jaguars Prediction & Picks

Game Prediction

Jaguars -3.5 Probability

Best Bet

Player Prop Picks

Same Game Parlay Picks

Correct Score Prediction

Panthers vs Jaguars Odds

Last 5 & H2H

Live Streaming

Team News

Carolina Panthers Injuries

Jacksonville Jaguars Injuries

Previous Carolina Panthers Lineups

Previous Jacksonville Jaguars Lineups

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