Bears vs 49ers Prediction, Picks & Odds | 28 Dec 2025

NFL Betting Preview: Bears vs Niners

The Chicago Bears battle the San Francisco 49ers at Levi's Stadium, with kickoff scheduled for 20:20 on Sunday, December 28.

The Bears should be able to battle hard and our prediction is that the underdogs will cover the line against the Niners. It’s set at a more than generous +3 and you can get -104.

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Chicago Bears made it back-to-back wins after a 22-16 (OT) home success over Green Bay Packers at Soldier Field. The Bears recorded 400 yards, breaking down to 250 passing and 150 rushing yards. They managed 20 first downs and produced 2 touchdowns, with both scores coming by pass.

San Francisco 49ers have triumphed in their last five games. The latest of these was on the road where Indianapolis Colts were beaten 48-27 at Lucas Oil Stadium. The 49ers moved the ball for 440 yards, with 295 through the air and 145 on the ground. They moved the chains 28 times and produced 6 touchdowns.

Head-to-Head Statistics

It was a 38-13 win for the Niners at Levi's Stadium when they last played the Bears. The Niners have triumphed in two of the previous 3 clashes between these teams.

Quarterbacks

Caleb Williams

224.5 Passing Yards

Over -114

Under -114

Brock Purdy

254.5 Passing Yards

Over -114

Under -114

Bears vs 49ers Prediction & Picks

Dive into our full Bears vs 49ers betting preview, featuring an expert match prediction, a projected scoreline, top player prop bets and a bet builder designed for value.

Game Prediction

Our pick is that the Bears will cover the line and prove to be competitive. It’s currently set at +3 for this NFL showdown and that makes lots of appeal, with odds of -104 available.

The NFL handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our picks. We combine this insight with up-to-date stats for sharper predictions.

Key Bears vs 49ers stats:

• The +3 line has been covered by Bears in 8 of their last 10 games.
• The +3 line has been covered by Bears in 12 of their last 15 games this season.
• The +3 line has been covered by Bears in 2 consecutive games.
• The -3 line hasn’t been covered by 49ers in 6 of their last 10 games at home.

Bears +3 Probability

The best betting apps make it a 51% chance that our pick is settled as a winner. In our opinion, there’s actually a probability of success between 55-60%. It is the reason why we are recommending this wager.

If you want a viable alternative to backing the Bears on the spread, then the Winning Margin lines could be up your street. Choose from a range of options.

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Our Game Prediction

Bears +3 @ -104 Watch Live Bet Now

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Player Prop Picks

Top Pick: D'Andre Swift Anytime TD +115

D'Andre Swift (Bears) is available at +115 to record a TD. We think this is the pick of the player props, with generous odds available when it comes to backing him to score a touchdown at any time.

Latest D'Andre Swift Player Prop Odds

Touchdown

Anytime

+115

First

+750

Rushing Yards

Over 59.5

-114

Under 59.5

-114

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Colston Loveland Over 40.5 Receiving Yards -114

You can back Colston Loveland (Bears) at -114 to go over 40.5 receiving yards. The line for him on the Overs is highly appealing, with Player Receiving Yards bettors able to get plenty of juice.

Latest Colston Loveland Player Prop Odds

Touchdown

Anytime

+200

First

+1300

Receiving Yards

Over 40.5

-114

Under 40.5

-114

Correct Score Prediction

Bears 27 - 23 49ers

There might not be too much between these teams, with our correct score prediction being a 27-23 win for the Bears. There are enormous odds available when it comes to this pick.

Bears vs 49ers Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

For this game, the sportsbooks’ Moneyline betting odds mean San Francisco 49ers are -167 favorites to win and that means a 63% chance of landing a victory. For those wanting to oppose the market leader, you can get +142 about Chicago Bears.

3 is where the spread lies, with total points being 52.5 right now. A bet on the Totals allows fans to use the latest NFL data to good effect. Those that want to back Under 52.5 can find odds of -110 available.

You’ll find a huge variety of game lines and team props for every matchup. The top NFL sportsbooks provide an impressive mix of pre-game and in-game options to suit your betting style.

Moneyline

Bears

+142

49ers

-167

Point Spread

Bears +3

-104

49ers -3

-118

Total Points

Under 52.5

-110

Over 52.5

-110

Christian McCaffrey is favorite to be First Touchdown Scorer at +350. If you want to back him to score the last TD, you can get similar odds.

Touchdown

Christian McCaffrey (49ers)

First TD

+350

Anytime TD

-270

Jauan Jennings (49ers)

First TD

+750

Anytime TD

+105

George Kittle (49ers)

First TD

+750

Anytime TD

+105

D'Andre Swift (Bears)

First TD

+750

Anytime TD

+115

Kyle Monangai (Bears)

First TD

+950

Anytime TD

+140

DJ Moore (Bears)

First TD

+1200

Anytime TD

+190

Colston Loveland (Bears)

First TD

+1300

Anytime TD

+200

Luther Burden III (Bears)

First TD

+1300

Anytime TD

+210

Ricky Pearsall (49ers)

First TD

+1500

Anytime TD

+170

Jake Tonges (49ers)

First TD

+1500

Anytime TD

+170

Caleb Williams (Bears)

First TD

+1800

Anytime TD

+300

Brian Robinson Jr. (49ers)

First TD

+2000

Anytime TD

+320

Kendrick Bourne (49ers)

First TD

+2000

Anytime TD

+250

Olamide Zaccheaus (Bears)

First TD

+2700

Anytime TD

+360

Cole Kmet (Bears)

First TD

+2700

Anytime TD

+360

Demarcus Robinson (49ers)

First TD

+2700

Anytime TD

+360

Brock Purdy (49ers)

First TD

+3000

Anytime TD

+500

Luke Farrell (49ers)

First TD

+3300

Anytime TD

+480

Kyle Juszczyk (49ers)

First TD

+3300

Anytime TD

+480

Devin Duvernay (Bears)

First TD

+6000

Anytime TD

+1000

Jahdae Walker (Bears)

First TD

+6000

Anytime TD

+1000

Jordan Watkins (49ers)

First TD

+6500

Anytime TD

+950

Skyy Moore (49ers)

First TD

+6500

Anytime TD

+950

Durham Smythe (Bears)

First TD

+8000

Anytime TD

+1400

James Jordan (49ers)

First TD

+10000

Anytime TD

+2000

Isaac Guerendo (49ers)

First TD

+10000

Anytime TD

+2000

Travis Homer (Bears)

First TD

+10000

Anytime TD

+2200

Receiving Yards

DJ Moore (Bears)

Over 46.5

-114

Under 46.5

-114

Luther Burden III (Bears)

Over 46.5

-114

Under 46.5

-114

Christian McCaffrey (49ers)

Over 42.5

-114

Under 42.5

-114

Colston Loveland (Bears)

Over 40.5

-114

Under 40.5

-114

Rushing Yards

Christian McCaffrey (49ers)

Over 66.5

-114

Under 66.5

-114

D'Andre Swift (Bears)

Over 59.5

-114

Under 59.5

-114

Kyle Monangai (Bears)

Over 43.5

-114

Under 43.5

-114

Brian Robinson Jr. (49ers)

Over 20.5

-114

Under 20.5

-114

Caleb Williams (Bears)

Over 16.5

-114

Under 16.5

-114

Brock Purdy (49ers)

Over 11.5

-114

Under 11.5

-114

Passing Yards

Brock Purdy (49ers)

Over 254.5

-114

Under 254.5

-114

Caleb Williams (Bears)

Over 224.5

-114

Under 224.5

-114

Niners Have Won Five of Their Last Ten Home Games

The Niners have five wins and five losses in the last 10 games at home, averaging 23.50 points scored and 21.10 points allowed.

The Bears have six wins and four losses in the last 10 games away from home, posting 23.40 points per contest while yielding 28.40.

The last Levi's Stadium meeting saw the Niners beat the Bears 38-13.

Last 10 Games		W-L	P	PF	PA	O52.5	U52.5
49ers Home Stats		5-5	44.60	23.50	21.10	3	7
Bears Away Stats		6-4	51.80	23.40	28.40	2	8

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O52.5 = Games Over 52.5 Points
• U52.5 = Games Under 52.5 Points

Latest regular season and playoff games stats.

Chicago Bears Stats

San Francisco 49ers Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• +3 Betting Line: Have covered the spread in 8 of the last 10 games
• +3 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -3 Betting Line: Have covered the spread in 7 of the last 10 games
• -3 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 47.40 pts in the previous 10 games
• Game Totals on the Road: An average of 51.80 pts in the previous 10 games on the road
• Over 52.5: Covered in 2 of the previous 10 games
• Over 52.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 26.10 pts and allowed 21.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 23.40 pts and allowed 28.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 50.80 pts in the previous 10 games
• Game Totals at Home: An average of 44.60 pts in the previous 10 home games
• Over 52.5: Covered in 5 of the previous 10 games
• Over 52.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 28.60 pts and allowed 22.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 23.50 pts and allowed 21.10 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 387.40 Yds. Allowed 337.40 Yds
• Rushing Yards: Gained 172.20 Yds. Allowed 118.30 Yds
• Passing Yards: Gained 215.20 Yds. Allowed 219.10 Yds
• Total Touchdowns: Scored 2.80 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 22.30. Allowed 18.80
• Total Turnovers: Committed 0.60. Committed by opponents 1.90
• Total Penalties: Committed 6.60. Committed by opponents 5.90
• Penalty Yards: Lost 54.40 Yds. Gained 40.90 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 342.00 Yds. Allowed 340.50 Yds
• Rushing Yards: Gained 113.20 Yds. Allowed 100.30 Yds
• Passing Yards: Gained 228.80 Yds. Allowed 240.20 Yds
• Total Touchdowns: Scored 3.30 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 1.20 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 2.00 TD. Allowed 1.90 TD
• Total 1st Downs: Picked up 22.20. Allowed 19.90
• Total Turnovers: Committed 1.20. Committed by opponents 1.10
• Total Penalties: Committed 4.30. Committed by opponents 6.20
• Penalty Yards: Lost 29.70 Yds. Gained 43.90 Yds

Last 10 Games on the Road

• Total Yards: Gained 350.70 Yds. Allowed 366.20 Yds
• Rushing Yards: Gained 148.20 Yds. Allowed 138.00 Yds
• Passing Yards: Gained 202.50 Yds. Allowed 228.20 Yds
• Total Touchdowns: Scored 2.40 TD. Allowed 3.40 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 2.20 TD
• Total 1st Downs: Picked up 20.30. Allowed 20.40
• Total Turnovers: Committed 0.90. Committed by opponents 1.80
• Total Penalties: Committed 7.30. Committed by opponents 5.60
• Penalty Yards: Lost 54.60 Yds. Gained 41.30 Yds

Last 10 Home Games

• Total Yards: Gained 362.60 Yds. Allowed 300.60 Yds
• Rushing Yards: Gained 108.90 Yds. Allowed 110.60 Yds
• Passing Yards: Gained 253.70 Yds. Allowed 190.00 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 22.20. Allowed 18.40
• Total Turnovers: Committed 1.80. Committed by opponents 0.50
• Total Penalties: Committed 5.20. Committed by opponents 5.10
• Penalty Yards: Lost 36.90 Yds. Gained 39.70 Yds

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