Packers vs Browns Prediction, Picks & Odds | 21 Sep 2025

NFL Betting Preview: Packers vs Browns

The Green Bay Packers face off against the Cleveland Browns in this NFL Week 3 matchup at Huntington Bank Field, with kickoff scheduled for 13:00 on Sunday, September 21. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Our betting prediction is for the Packers to cover the appealing -7.5 line against the Browns. They should be able to win by a more comfortable margin and odds of -110 are available on the spread.

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Green Bay Packers beat Washington Commanders in their previous game, making it back-to-back victories. It was a 27-18 home win at Lambeau Field. The Packers recorded 404 yards, breaking down to 269 passing and 135 rushing yards. The offense generated 22 first downs and produced 3 touchdowns.

Cleveland Browns lost on the road in their last game, making it back-to-back defeats. Baltimore Ravens won 41-17 at M&T Bank Stadium. The Browns finished with 322 yards, including 207 passing and 115 rushing yards. They produced 17 first downs and found the end zone on two occasions.

Head-to-Head Statistics

The Packers had the edge in the most recent matchup between these teams. At Lambeau Field, they recorded a 24-22 win over the Browns.

Quarterbacks

Jordan Love

221.5 Passing Yards

Over -112

Under -112

Joe Flacco

229.5 Passing Yards

Over -112

Under -112

Packers vs Browns Prediction & Picks

We’ve got your Packers vs Browns bets covered, including our expert match prediction, top correct score pick, must-see player props and a tailored bet builder built for value.

Game Prediction

Back the Packers against the spread, with a generous betting line of -7.5 that the favorites get the job done in this NFL matchup. There are odds of -110 that are currently on offer for this value pick.

Injuries can influence the outcome and our NFL handicappers factor that in alongside the latest form guide. We apply the same approach to the stats to build the clearest picture of how the game might unfold.

Key Packers vs Browns stats:

• The -7.5 line has been covered by Packers in 6 of their last 10 games.
• The -7.5 line has been covered by Packers in 2 consecutive games.
• The +7.5 line hasn’t been covered by Browns in 8 of their last 10 games.
• The +7.5 line hasn’t been covered by Browns in 4 of their last 5 games.

Packers -7.5 Probability

According to the latest odds, there’s a 52.4% likelihood of our pick landing a return. However, our analysts research has found that the actual probability is closer to 60%. This is why we can recommend this bet.

There’s the option to move the line for your spread pick and this enables bettors to get bigger odds. If you’re prepared for additional risk, you can get more bang for your buck.

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Our Game Prediction

Packers -7.5 @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (19:26, 19 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Joe Flacco Under 222.5 Passing Yards -114

You can back Joe Flacco (Browns) at -114 to end with fewer than 222.5 passing yards. The line looks too high and we’re confident he’ll fall short of the QB Passing Yards total.

Latest Joe Flacco Player Prop Odds

Touchdown

Anytime

+3000

First

+10000

Passing Yards

Over 229.5

-112

Under 229.5

-112

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Quinshon Judkins Under 40.5 Rushing Yards -114

Quinshon Judkins (Packers) can be backed at -114 to finish with fewer than 40.5 rushing yards. He is likely to fall short of the line, making this Player Rushing Yards bet an appealing option.

Latest Quinshon Judkins Player Prop Odds

Touchdown

Anytime

+230

First

+1100

Receiving Yards

Over 8.5

-108

Under 8.5

-118

Rushing Yards

Over 42.5

-112

Under 42.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Packers 27 - 10 Browns

The Packers to win by a 27-10 scoreline could be worth a chance. There’s a massive potential return if you can land this bet on the money and it should provide some entertainment.

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Packers vs Browns Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

You might not get rich backing Green Bay Packers at -417. However, the sportsbooks’ betting odds imply a 81% chance of winning this game. The market suggests that Cleveland Browns are least likely to win at +330.

The spread is 7.5 and the total points line is currently 41.5. The advantage of the Totals is that you only have to choose from one of two options. If you’re going for Under 41.5, this outcome can be backed at -110.

National Football League fans are spoilt for choice thanks to the wide range of game lines and team props which are available for every game on the coupon. Visit the top betting apps and find the best value wagers.

Moneyline

Packers

-417

Browns

+330

Point Spread

Packers -7.5

-104

Browns +7.5

-118

Total Points

Under 41.5

-110

Over 41.5

-110

Josh Jacobs can be backed to score a touchdown at anytime at -175. He is the favorite to score the first TD at odds of +300.

Touchdown

Josh Jacobs (Packers)

First TD

+300

Anytime TD

-175

Romeo Doubs (Packers)

First TD

+850

Anytime TD

+195

Tucker Kraft (Packers)

First TD

+1100

Anytime TD

+250

Dontayvion Wicks (Packers)

First TD

+1100

Anytime TD

+250

Quinshon Judkins (Browns)

First TD

+1100

Anytime TD

+230

Matthew Golden (Packers)

First TD

+1400

Anytime TD

+300

Jerry Jeudy (Browns)

First TD

+1400

Anytime TD

+250

Cedric Tillman (Browns)

First TD

+1600

Anytime TD

+310

David Njoku (Browns)

First TD

+2000

Anytime TD

+350

Harold Fannin Jr. (Browns)

First TD

+2000

Anytime TD

+420

Dylan Sampson (Browns)

First TD

+2200

Anytime TD

+400

Luke Musgrave (Packers)

First TD

+2200

Anytime TD

+550

Jordan Love (Packers)

First TD

+2200

Anytime TD

+550

Jerome Ford (Browns)

First TD

+2700

Anytime TD

+500

Chris Brooks (Packers)

First TD

+3300

Anytime TD

+850

Emanuel Wilson (Packers)

First TD

+4000

Anytime TD

+950

Savion Williams (Packers)

First TD

+4500

Anytime TD

+1200

Malik Heath (Packers)

First TD

+5000

Anytime TD

+1400

John FitzPatrick (Packers)

First TD

+6500

Anytime TD

+1800

Isaiah Bond (Browns)

First TD

+8000

Anytime TD

+1300

Jamari Thrash (Browns)

First TD

+8000

Anytime TD

+1600

Joe Flacco (Browns)

First TD

+10000

Anytime TD

+3000

Blake Whiteheart (Browns)

First TD

+10000

Anytime TD

+3500

DeAndre Carter (Browns)

First TD

+10000

Anytime TD

+3000

Raheim Sanders (Browns)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Jerry Jeudy (Browns)

Over 50.5

-116

Under 50.5

-110

Tucker Kraft (Packers)

Over 40.5

-112

Under 40.5

-112

Romeo Doubs (Packers)

Over 39.5

-112

Under 39.5

-112

Cedric Tillman (Browns)

Over 39.5

-112

Under 39.5

-112

Dontayvion Wicks (Packers)

Over 38.5

-127

Under 38.5

-102

David Njoku (Browns)

Over 37.5

-112

Under 37.5

-112

Harold Fannin Jr. (Browns)

Over 34.5

-112

Under 34.5

-112

Matthew Golden (Packers)

Over 32.5

-112

Under 32.5

-112

Josh Jacobs (Packers)

Over 10.5

-112

Under 10.5

-112

Quinshon Judkins (Browns)

Over 8.5

-108

Under 8.5

-118

Dylan Sampson (Browns)

Over 8.5

-102

Under 8.5

-123

Rushing Yards

Josh Jacobs (Packers)

Over 77.5

-112

Under 77.5

-112

Quinshon Judkins (Browns)

Over 42.5

-112

Under 42.5

-112

Jerome Ford (Browns)

Over 13.5

-112

Under 13.5

-112

Jordan Love (Packers)

Over 5.5

-112

Under 5.5

-112

Passing Yards

Joe Flacco (Browns)

Over 229.5

-112

Under 229.5

-112

Jordan Love (Packers)

Over 221.5

-112

Under 221.5

-112

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Browns Currently at Three Home Losses in a Row

The Browns have endured a run of three straight defeats at Huntington Bank Field. They have gone 4-6 across their last 10 home games, putting up 17.50 points on average and giving up 20.70.

The Packers have a 5-5 record in their last 10 games on the road, averaging 25.00 points scored and 23.30 points allowed.

The Packers earned a 23-10 win against the Browns in the teams’ last meeting at Huntington Bank Field.

Last 10 Games		W-L	P	PF	PA	O41.5	U41.5
Browns Home Stats		4-6	38.20	17.50	20.70	3	7
Packers Away Stats		5-5	48.30	25.00	23.30	8	2

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O41.5 = Games Over 41.5 Points
• U41.5 = Games Under 41.5 Points

Latest regular season and playoff games stats.

Green Bay Packers Stats

Cleveland Browns Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 1 win and 9 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• -7.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -7.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road

Point Spread

• +7.5 Betting Line: Have covered the spread in 2 of the last 10 games
• +7.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 45.20 pts in the previous 10 games
• Game Totals on the Road: An average of 48.30 pts in the previous 10 games on the road
• Over 41.5: Covered in 7 of the previous 10 games
• Over 41.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 27.40 pts and allowed 17.80 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 25.00 pts and allowed 23.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 42.30 pts in the previous 10 games
• Game Totals at Home: An average of 39.50 pts in the previous 10 home games
• Over 41.5: Covered in 5 of the previous 10 games
• Over 41.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 14.30 pts and allowed 28.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 17.20 pts and allowed 22.30 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 339.40 Yds. Allowed 284.20 Yds
• Rushing Yards: Gained 131.70 Yds. Allowed 75.90 Yds
• Passing Yards: Gained 207.70 Yds. Allowed 208.30 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 1.90 TD
• Rushing Touchdowns: Scored 1.80 TD. Allowed 0.30 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 19.30. Allowed 17.60
• Total Turnovers: Committed 0.90. Committed by opponents 1.30
• Total Penalties: Committed 6.40. Committed by opponents 7.10
• Penalty Yards: Lost 52.80 Yds. Gained 58.20 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 329.30 Yds. Allowed 324.50 Yds
• Rushing Yards: Gained 95.30 Yds. Allowed 119.30 Yds
• Passing Yards: Gained 234.00 Yds. Allowed 205.20 Yds
• Total Touchdowns: Scored 1.80 TD. Allowed 3.50 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.90 TD
• Total 1st Downs: Picked up 19.10. Allowed 17.20
• Total Turnovers: Committed 2.60. Committed by opponents 0.70
• Total Penalties: Committed 6.10. Committed by opponents 6.40
• Penalty Yards: Lost 47.40 Yds. Gained 50.10 Yds

Last 10 Games on the Road

• Total Yards: Gained 347.30 Yds. Allowed 348.40 Yds
• Rushing Yards: Gained 133.90 Yds. Allowed 112.10 Yds
• Passing Yards: Gained 213.40 Yds. Allowed 236.30 Yds
• Total Touchdowns: Scored 2.80 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 1.40 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 18.70. Allowed 21.10
• Total Turnovers: Committed 1.30. Committed by opponents 1.40
• Total Penalties: Committed 6.00. Committed by opponents 6.10
• Penalty Yards: Lost 45.20 Yds. Gained 56.90 Yds

Last 10 Home Games

• Total Yards: Gained 307.70 Yds. Allowed 301.70 Yds
• Rushing Yards: Gained 91.20 Yds. Allowed 97.20 Yds
• Passing Yards: Gained 216.50 Yds. Allowed 204.50 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 18.50. Allowed 16.40
• Total Turnovers: Committed 2.60. Committed by opponents 0.50
• Total Penalties: Committed 7.10. Committed by opponents 7.50
• Penalty Yards: Lost 54.70 Yds. Gained 54.80 Yds

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