Jaguars vs Colts Prediction, Picks & Odds | 28 Dec 2025

NFL Betting Preview: Jaguars vs Colts

The Jacksonville Jaguars go up against the Indianapolis Colts at Lucas Oil Stadium, with kickoff scheduled for 13:00 on Sunday, December 28.

There are odds of -110 available for our Colts vs Jaguars prediction. We think that the points will be racked up cumulatively and we’re going for Over 48.5 in total.

Think this one’s going over? Snag the latest BetMGM promo code and check out our in-depth site review before placing your bet.

Jacksonville Jaguars have won their previous six games. A 34-20 triumph recently occurred on the road at Empower Field at Mile High when playing Denver Broncos. The Jaguars put up 346 yards, split between 265 passing and 81 rushing yards. They picked up 22 first downs and found the end zone 4 times, 3 by pass and one by run.

Indianapolis Colts have lost on their last five outings. In a recent home game at Lucas Oil Stadium, they were turned over 48-27 by San Francisco 49ers. The Colts generated 312 yards, including 254 passing and 58 rushing yards. The offense converted for 19 first downs and managed 3 touchdowns, 2 through the air along with one rushing score.

Head-to-Head Statistics

The Jaguars beat the Colts in their last head-to-head matchup. It was a 36-19 scoreline at EverBank Stadium. In the past 10 games between the teams, the Jaguars have won six.

Quarterbacks

Trevor Lawrence

247.5 Passing Yards

Over -112

Under -112

Philip Rivers

209.5 Passing Yards

Over -112

Under -112

Jaguars vs Colts Prediction & Picks

Prepare for Jaguars vs Colts with our expert betting guide featuring a trusted match prediction, likely scoreline, key player props and a well-crafted bet builder.

Game Prediction

Let’s go for Over 48.5 when these NFL teams lock horns. We think the line is too generous and we’re expecting the final total to be higher at -110.

It’s important to know which players are unavailable for the upcoming action along with the current form of each franchise. If you're after stats, you're in the right place because they form the foundation of our NFL picks.

Key Jaguars vs Colts stats:

• The 48.5 line has been covered in 4 of the last 5 Jaguars games.
• The 48.5 line has been covered in 5 of the last 7 Jaguars games on the road this season.
• The 48.5 line has been covered in the last 3 Jaguars games.
• The 48.5 line has been covered in 4 of the last 5 Colts games at home.
• The 48.5 line has been covered in 7 of the last 10 Colts games at home.
• The 48.5 line has been covered in the last 6 games between these teams.

Over 48.5 Probability

Based on the betting odds from the top sportsbooks, our pick has a 52.4% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and estimate the probability to be closer to 60%. The bet can be recommended for this precise reason.

Want more juice from your Over bet on the Totals? Bigger odds can be found if you move the line and go for a riskier wager. You can choose from a wide range of options.

Find top value before betting. Our guide includes the latest free bets and sign-up bonuses from trusted sites.

Our Game Prediction

Over 48.5 Points @ -110 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (19:25, 26 December 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Philip Rivers Over 206.5 Passing Yards -114

Philip Rivers (Colts) can be backed at -114 to rack up over 206.5 passing yards. We’re happy to take him to cover the QB Passing Yards line and bettors can place this wager with confidence.

Latest Philip Rivers Player Prop Odds

Touchdown

Anytime

+3300

First

+10000

Passing Yards

Over 209.5

-112

Under 209.5

-112

---

Michael Pittman Jr. Over 44.5 Receiving Yards -114

The odds for Michael Pittman Jr. (Colts) to surpass 44.5 receiving yards are -114. The line for him on the Overs is highly appealing, with Player Receiving Yards bettors able to get plenty of juice.

Latest Michael Pittman Jr. Player Prop Odds

Touchdown

Anytime

+280

First

+1400

Receiving Yards

Over 44.5

-112

Under 44.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Jaguars 31 - 21 Colts

For those looking to get more bang for their buck, consider a correct score bet on the Jaguars. Backing them to win 31-21 means you can land a potential monster return.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Jaguars vs Colts Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The Jacksonville Jaguars odds have been priced up by the sportsbooks and they are -100 betting favorites to land victory in this game which means a 50% chance of winning. Indianapolis Colts are the underdogs at -120 and they’re regarded as least likely to win.

The current spread is 1.5 and total points is 45.5. Having a wager on the Totals is one of the most popular NFL bets. The Over 45.5 selection is available to back at -110.

National Football League fans are spoilt for choice thanks to the wide range of game lines and team props which are available for every game on the coupon. Visit the top betting apps and find the best value wagers.

Moneyline

Jaguars

-100

Colts

-120

Point Spread

Jaguars +1.5

-112

Colts -1.5

-108

Total Points

Under 45.5

-110

Over 45.5

-110

The First TD Scorer favorite is Jonathan Taylor at +400. Similar odds can be found if you’re interested in this player to register the last touchdown.

Touchdown

Jonathan Taylor (Colts)

First TD

+400

Anytime TD

-185

Travis Etienne Jr. (Jaguars)

First TD

+410

Anytime TD

-196

Jakobi Meyers (Jaguars)

First TD

+900

Anytime TD

+155

Brian Thomas Jr (Jaguars)

First TD

+1100

Anytime TD

+190

Tyler Warren (Colts)

First TD

+1200

Anytime TD

+200

Brenton Strange (Jaguars)

First TD

+1200

Anytime TD

+220

Parker Washington (Jaguars)

First TD

+1400

Anytime TD

+240

Michael Pittman Jr. (Colts)

First TD

+1400

Anytime TD

+280

Trevor Lawrence (Jaguars)

First TD

+1600

Anytime TD

+260

Alec Pierce (Colts)

First TD

+1600

Anytime TD

+300

Josh Downs (Colts)

First TD

+1700

Anytime TD

+310

Bhayshul Tuten (Jaguars)

First TD

+2700

Anytime TD

+330

LeQuint Allen Jr. (Jaguars)

First TD

+2700

Anytime TD

+340

Tim Patrick (Jaguars)

First TD

+4000

Anytime TD

+650

Ameer Abdullah (Colts)

First TD

+4500

Anytime TD

+650

Quintin Morris (Jaguars)

First TD

+8000

Anytime TD

+1200

Will Mallory (Colts)

First TD

+8000

Anytime TD

+1100

Mo Alie-Cox (Colts)

First TD

+8000

Anytime TD

+1100

Tyler Goodson (Colts)

First TD

+10000

Anytime TD

+2500

Dyami Brown (Jaguars)

First TD

+10000

Anytime TD

+2500

Ashton Dulin (Colts)

First TD

+10000

Anytime TD

+1100

Laquon Treadwell (Colts)

First TD

+10000

Anytime TD

+3500

Philip Rivers (Colts)

First TD

+10000

Anytime TD

+3300

Drew Ogletree (Colts)

First TD

+10000

Anytime TD

+2200

DJ Giddens (Colts)

First TD

+10000

Anytime TD

+2500

Hunter Long (Jaguars)

First TD

+10000

Anytime TD

+2000

Johnny Mundt (Jaguars)

First TD

+10000

Anytime TD

+2000

DeeJay Dallas (Jaguars)

First TD

+10000

Anytime TD

+1600

Anthony Gould (Colts)

First TD

+10000

Anytime TD

+2000

Receiving Yards

Jakobi Meyers (Jaguars)

Over 59.5

-112

Under 59.5

-112

Brian Thomas Jr (Jaguars)

Over 49.5

-112

Under 49.5

-112

Tyler Warren (Colts)

Over 47.5

-112

Under 47.5

-112

Michael Pittman Jr. (Colts)

Over 44.5

-112

Under 44.5

-112

Parker Washington (Jaguars)

Over 42.5

-112

Under 42.5

-112

Brenton Strange (Jaguars)

Over 38.5

-112

Under 38.5

-112

Josh Downs (Colts)

Over 36.5

-112

Under 36.5

-112

Alec Pierce (Colts)

Over 30.5

-112

Under 30.5

-112

Jonathan Taylor (Colts)

Over 17.5

-112

Under 17.5

-112

Travis Etienne Jr. (Jaguars)

Over 17.5

-112

Under 17.5

-112

Rushing Yards

Jonathan Taylor (Colts)

Over 72.5

-112

Under 72.5

-112

Travis Etienne Jr. (Jaguars)

Over 66.5

-112

Under 66.5

-112

Trevor Lawrence (Jaguars)

Over 17.5

-112

Under 17.5

-112

Passing Yards

Trevor Lawrence (Jaguars)

Over 247.5

-112

Under 247.5

-112

Philip Rivers (Colts)

Over 209.5

-112

Under 209.5

-112

An increasing number of bettors are now enjoying micro betting on the NFL and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Colts Have Seven Wins From Last Ten Home Games

The Colts own a 7-3 mark in their past 10 home games, scoring 28.40 points per contest and conceding 22.80.

The Jaguars have chalked up three straight wins on the road. They have six wins and four losses in the last 10 games away from home, posting 24.50 points per contest while yielding 21.50.

The Colts earned a 26-23 win over the Jaguars the last time they played at Lucas Oil Stadium. Across the past 6 head-to-head meetings at Lucas Oil Stadium, the Colts have recorded five wins, with the Jaguars winning once.

Last 10 Games		W-L	P	PF	PA	O48.5	U48.5
Colts Home Stats		7-3	51.20	28.40	22.80	6	4
Jaguars Away Stats		6-4	46.00	24.50	21.50	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O48.5 = Games Over 48.5 Points
• U48.5 = Games Under 48.5 Points

Latest regular season and playoff games stats.

Jacksonville Jaguars Stats

Indianapolis Colts Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• -5.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -5.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road

Point Spread

• +5.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +5.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 49.50 pts in the previous 10 games
• Game Totals on the Road: An average of 46.00 pts in the previous 10 games on the road
• Over 48.5: Covered in 6 of the previous 10 games
• Over 48.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.30 pts and allowed 21.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 24.50 pts and allowed 21.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 51.80 pts in the previous 10 games
• Game Totals at Home: An average of 53.80 pts in the previous 10 home games
• Over 48.5: Covered in 6 of the previous 10 games
• Over 48.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 25.60 pts and allowed 26.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 30.90 pts and allowed 22.90 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 333.20 Yds. Allowed 302.30 Yds
• Rushing Yards: Gained 108.60 Yds. Allowed 82.00 Yds
• Passing Yards: Gained 224.70 Yds. Allowed 220.30 Yds
• Total Touchdowns: Scored 3.40 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 2.00 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 21.50. Allowed 19.50
• Total Turnovers: Committed 0.90. Committed by opponents 1.40
• Total Penalties: Committed 7.70. Committed by opponents 6.90
• Penalty Yards: Lost 67.20 Yds. Gained 59.60 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 341.10 Yds. Allowed 366.30 Yds
• Rushing Yards: Gained 121.60 Yds. Allowed 98.70 Yds
• Passing Yards: Gained 219.50 Yds. Allowed 267.60 Yds
• Total Touchdowns: Scored 3.00 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 1.40 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 20.10. Allowed 22.70
• Total Turnovers: Committed 1.50. Committed by opponents 1.10
• Total Penalties: Committed 5.30. Committed by opponents 5.80
• Penalty Yards: Lost 44.30 Yds. Gained 49.10 Yds

Last 10 Games on the Road

• Total Yards: Gained 323.30 Yds. Allowed 345.60 Yds
• Rushing Yards: Gained 109.80 Yds. Allowed 91.30 Yds
• Passing Yards: Gained 213.60 Yds. Allowed 254.30 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 19.40. Allowed 21.80
• Total Turnovers: Committed 1.30. Committed by opponents 1.40
• Total Penalties: Committed 7.60. Committed by opponents 6.30
• Penalty Yards: Lost 64.90 Yds. Gained 52.00 Yds

Last 10 Home Games

• Total Yards: Gained 398.20 Yds. Allowed 329.20 Yds
• Rushing Yards: Gained 171.20 Yds. Allowed 107.40 Yds
• Passing Yards: Gained 227.00 Yds. Allowed 221.80 Yds
• Total Touchdowns: Scored 3.60 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 1.70 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 22.70. Allowed 21.30
• Total Turnovers: Committed 0.60. Committed by opponents 1.50
• Total Penalties: Committed 5.90. Committed by opponents 4.90
• Penalty Yards: Lost 47.30 Yds. Gained 51.00 Yds

Top American Football Pages