Raiders vs Colts Prediction, Picks & Odds | 05 Oct 2025

NFL Betting Preview: Raiders vs Colts

The Las Vegas Raiders square off against the Indianapolis Colts in this NFL Week 5 matchup at Lucas Oil Stadium, with kickoff scheduled for 13:00 on Sunday, October 5. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

The Colts should secure a comfortable win and a bet on the spread could be the best way forward. Back the favorites off -6.5 to cover the line when they clash with the Raiders at -118.

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Las Vegas Raiders suffered a third consecutive defeat when losing 25-24 in their previous game. This was at home to Chicago Bears at Allegiant Stadium. The Raiders put up 357 yards, split between 117 passing and 240 rushing yards. They picked up 17 first downs and produced 3 touchdowns, 2 through the air along with one rushing score.

Indianapolis Colts have landed two home wins on the spin. It was a road defeat to Los Angeles Rams in their last game, losing 27-20 at SoFi Stadium. The Colts put up 333 total yards, made up of 248 through the air and 85 on the ground. The offense moved the chains 17 times and scored 2 touchdowns, splitting them between the run and the pass.

Head-to-Head Statistics

The Colts have claimed back-to-back victories over the Raiders. At Allegiant Stadium they won 25-20 before winning 23-20 at Lucas Oil Stadium. We’ve seen three Colts wins in the past 5 meetings between the teams.

Quarterbacks

Geno Smith

226.5 Passing Yards

Over -112

Under -112

Daniel Jones

231.5 Passing Yards

Over -112

Under -112

Raiders vs Colts Prediction & Picks

We cover the essential Raiders vs Colts betting angles, featuring our main match prediction, correct score pick, top player prop plays and a carefully crafted bet builder.

Game Prediction

It’s time to go for the Colts against the spread, especially with an attractive -6.5 line at -118. Our pick is that the favorites can achieve a comfortable win in this NFL matchup.

To deliver the best possible NFL predictions, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date stats available.

Key Raiders vs Colts stats:

• The +6.5 line hasn’t been covered by Raiders in 3 of their last 5 games.
• The +6.5 line hasn’t been covered by Raiders in 11 of their last 20 games.

Colts -6.5 Probability

If you go by the best betting sites, our pick has a 54.1% chance of winning. Based on our analysts research, we calculate the actual probability to be closer to 60%. It's therefore regarded as a value wager.

A Bet Builder provides you with the chance to combine the Colts against the spread with other picks. For every additional selection, the odds are boosted.

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Our Game Prediction

Colts -6.5 @ -118 Bet Now

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Player Prop Picks

Top Pick: Daniel Jones Over 226.5 Passing Yards -114

Daniel Jones (Colts) is priced at -114 to accumulate over 226.5 passing yards. The line for him on the Overs is highly appealing, with QB Passing Yards bettors able to get plenty of juice.

Latest Daniel Jones Player Prop Odds

Touchdown

Anytime

+165

First

+900

Passing Yards

Over 231.5

-112

Under 231.5

-112

Rushing Yards

Over 18.5

-112

Under 18.5

-112

Correct Score Prediction

Raiders 20 - 34 Colts

For those wanting a big return from a small stake, consider the correct score lines. For example, the Colts can be backed to win 34-20 at huge betting odds.

Raiders vs Colts Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

With a 56% chance of securing victory, Indianapolis Colts are favorites for this game and the sportsbooks have them at betting odds of -125. At +105, Las Vegas Raiders are regarded as having a lower probability of winning.

1.5 is the spread and 44.5 is the total points line. NFL fans regularly enjoy the opportunity to bet on the Totals. Those expecting a low total can back Under 44.5 at -108.

If you're betting on the matchups, it's worth checking out the best NFL sportsbooks, where you'll find a massive range of game lines and team props. You can place your bets before kickoff or while the action is underway.

Moneyline

Raiders

+105

Colts

-125

Point Spread

Raiders +1.5

-110

Colts -1.5

-110

Total Points

Under 44.5

-108

Over 44.5

-112

Jonathan Taylor is available at -250 when it comes to Anytime Touchdown Scorer. The favorite is now priced at odds of +280 to score the first TD.

Touchdown

Jonathan Taylor (Colts)

First TD

+280

Anytime TD

-250

Ashton Jeanty (Raiders)

First TD

+700

Anytime TD

-115

Michael Pittman Jr. (Colts)

First TD

+800

Anytime TD

+155

Tyler Warren (Colts)

First TD

+850

Anytime TD

+160

Daniel Jones (Colts)

First TD

+900

Anytime TD

+165

Alec Pierce (Colts)

First TD

+1200

Anytime TD

+220

Jakobi Meyers (Raiders)

First TD

+1200

Anytime TD

+165

Josh Downs (Colts)

First TD

+1300

Anytime TD

+280

Brock Bowers (Raiders)

First TD

+1400

Anytime TD

+200

Tre Tucker (Raiders)

First TD

+1500

Anytime TD

+220

Adonai Mitchell (Colts)

First TD

+2500

Anytime TD

+470

Dont'e Thornton Jr. (Raiders)

First TD

+2700

Anytime TD

+430

Ashton Dulin (Colts)

First TD

+3000

Anytime TD

+470

Ian Thomas (Raiders)

First TD

+3500

Anytime TD

+490

Michael Mayer (Raiders)

First TD

+4500

Anytime TD

+500

Geno Smith (Raiders)

First TD

+5000

Anytime TD

+950

DJ Giddens (Colts)

First TD

+5000

Anytime TD

+800

Zamir White (Raiders)

First TD

+6000

Anytime TD

+1100

Raheem Mostert (Raiders)

First TD

+6000

Anytime TD

+1100

Mo Alie-Cox (Colts)

First TD

+6000

Anytime TD

+1200

Tyler Goodson (Colts)

First TD

+8000

Anytime TD

+1500

Ameer Abdullah (Raiders)

First TD

+8000

Anytime TD

+1500

Albert Okwuegbunam (Raiders)

First TD

+8000

Anytime TD

+1200

Anthony Gould (Colts)

First TD

+8000

Anytime TD

+1600

Dylan Laube (Raiders)

First TD

+8000

Anytime TD

+1200

Justin Shorter (Raiders)

First TD

+10000

Anytime TD

+1500

Drew Ogletree (Colts)

First TD

+10000

Anytime TD

+2200

Will Mallory (Colts)

First TD

+10000

Anytime TD

+2200

Jack Bech (Raiders)

First TD

+10000

Anytime TD

+1600

Alex Bachman (Raiders)

First TD

+10000

Anytime TD

+1600

Carter Runyon (Raiders)

First TD

+10000

Anytime TD

+2700

Receiving Yards

Jakobi Meyers (Raiders)

Over 71.5

-112

Under 71.5

-112

Tyler Warren (Colts)

Over 60.5

-112

Under 60.5

-112

Michael Pittman Jr. (Colts)

Over 55.5

-112

Under 55.5

-112

Tre Tucker (Raiders)

Over 52.5

-112

Under 52.5

-112

Brock Bowers (Raiders)

Over 47.5

-114

Under 47.5

-114

Josh Downs (Colts)

Over 36.5

-112

Under 36.5

-112

Dont'e Thornton Jr. (Raiders)

Over 32.5

-112

Under 32.5

-112

Alec Pierce (Colts)

Over 32.5

-114

Under 32.5

-114

Adonai Mitchell (Colts)

Over 26.5

-114

Under 26.5

-114

Jonathan Taylor (Colts)

Over 16.5

-112

Under 16.5

-112

Ashton Jeanty (Raiders)

Over 16.5

-112

Under 16.5

-112

Rushing Yards

Jonathan Taylor (Colts)

Over 86.5

-112

Under 86.5

-112

Ashton Jeanty (Raiders)

Over 66.5

-112

Under 66.5

-112

Daniel Jones (Colts)

Over 18.5

-112

Under 18.5

-112

Raheem Mostert (Raiders)

Over 12.5

-112

Under 12.5

-112

Geno Smith (Raiders)

Over 10.5

-112

Under 10.5

-112

Passing Yards

Daniel Jones (Colts)

Over 231.5

-112

Under 231.5

-112

Geno Smith (Raiders)

Over 226.5

-112

Under 226.5

-112

You don’t have to wait for the final outcome when it comes to NFL micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Colts Eye Another Home Win

The Colts have put together four consecutive victories at Lucas Oil Stadium. They have seven wins and three losses in the last 10 games at home, posting 24.30 points per matchup while yielding 22.20.

The Raiders own a 3-7 mark in their past 10 games on the road, scoring 20.10 points per contest and conceding 26.30.

The last time the teams met at Lucas Oil Stadium, the Colts defeated the Raiders 23-20. Looking at the last 3 head-to-heads at Lucas Oil Stadium, the Raiders have tallied two victories, with the Colts winning once.

Last 10 Games		W-L	P	PF	PA	O47.5	U47.5
Colts Home Stats		7-3	46.50	24.30	22.20	6	4
Raiders Away Stats		3-7	46.40	20.10	26.30	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O47.5 = Games Over 47.5 Points
• U47.5 = Games Under 47.5 Points

Latest regular season and playoff games stats.

Las Vegas Raiders Stats

Indianapolis Colts Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 39.90 pts in the previous 10 games
• Game Totals on the Road: An average of 46.40 pts in the previous 10 games on the road
• Over 47.5: Covered in 3 of the previous 10 games
• Over 47.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 18.00 pts and allowed 21.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 20.10 pts and allowed 26.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 52.40 pts in the previous 10 games
• Game Totals at Home: An average of 46.50 pts in the previous 10 home games
• Over 47.5: Covered in 6 of the previous 10 games
• Over 47.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 26.40 pts and allowed 26.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 24.30 pts and allowed 22.20 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 325.30 Yds. Allowed 338.40 Yds
• Rushing Yards: Gained 99.30 Yds. Allowed 108.40 Yds
• Passing Yards: Gained 226.00 Yds. Allowed 230.00 Yds
• Total Touchdowns: Scored 1.80 TD. Allowed 2.20 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 18.10. Allowed 17.30
• Total Turnovers: Committed 1.50. Committed by opponents 1.20
• Total Penalties: Committed 5.70. Committed by opponents 7.30
• Penalty Yards: Lost 51.50 Yds. Gained 50.30 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 375.30 Yds. Allowed 329.90 Yds
• Rushing Yards: Gained 157.20 Yds. Allowed 105.10 Yds
• Passing Yards: Gained 218.10 Yds. Allowed 224.80 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 3.20 TD
• Rushing Touchdowns: Scored 1.60 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.90 TD
• Total 1st Downs: Picked up 20.90. Allowed 19.40
• Total Turnovers: Committed 1.40. Committed by opponents 1.40
• Total Penalties: Committed 6.30. Committed by opponents 5.90
• Penalty Yards: Lost 48.10 Yds. Gained 60.60 Yds

Last 10 Games on the Road

• Total Yards: Gained 330.20 Yds. Allowed 341.10 Yds
• Rushing Yards: Gained 89.60 Yds. Allowed 114.40 Yds
• Passing Yards: Gained 240.70 Yds. Allowed 226.70 Yds
• Total Touchdowns: Scored 1.90 TD. Allowed 3.00 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 19.20. Allowed 19.20
• Total Turnovers: Committed 1.50. Committed by opponents 1.00
• Total Penalties: Committed 6.70. Committed by opponents 7.20
• Penalty Yards: Lost 56.10 Yds. Gained 54.40 Yds

Last 10 Home Games

• Total Yards: Gained 365.80 Yds. Allowed 351.90 Yds
• Rushing Yards: Gained 159.40 Yds. Allowed 123.20 Yds
• Passing Yards: Gained 206.40 Yds. Allowed 228.70 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 1.50 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 19.30. Allowed 21.20
• Total Turnovers: Committed 0.90. Committed by opponents 1.70
• Total Penalties: Committed 6.10. Committed by opponents 5.30
• Penalty Yards: Lost 45.10 Yds. Gained 44.70 Yds

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