Chargers vs Raiders Prediction, Picks & Odds | 15 Sep 2025

NFL Betting Preview: Chargers vs Raiders

The Los Angeles Chargers face the Las Vegas Raiders in this NFL Week 2 Monday Night Football matchup at SoFi Stadium, with kickoff scheduled for 22:00 on Monday, September 15. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Go for Under at -118. It might be defenses on top when the Raiders clash with the Chargers, with the 46.5 points line looking on the high side when it comes to the totals.

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Los Angeles Chargers won their previous game, beating Kansas City Chiefs at home. It was a 27-21 win at SoFi Stadium. The Chargers put up 394 yards, including 304 passing and 90 rushing yards. They moved the chains 22 times and produced 3 touchdowns.

Las Vegas Raiders triumphed in their last game. It was on the road where New England Patriots were beaten 20-13 at Gillette Stadium. The Raiders put up 389 yards, including 333 passing and 56 rushing yards. They produced 21 first downs and found the end zone on two occasions.

Head-to-Head Statistics

The Chargers have beaten the Raiders in the last two meetings. They won 22-10 at SoFi Stadium and triumphed 34-20 at Allegiant Stadium. In the past 10 H2H meetings, the Chargers have won six.

Quarterbacks

Justin Herbert

259.5 Passing Yards

Over -112

Under -112

Geno Smith

246.5 Passing Yards

Over -112

Under -112

Chargers vs Raiders Prediction & Picks

Join us as we dissect the top Chargers vs Raiders betting picks — from the main match prediction and scoreline forecast to standout player props and a value-focused bet builder.

Game Prediction

We’re confident about the number of points to be scored when the teams take to the field in this NFL matchup. Therefore, the pick is Under 46.5 points which is available at -118.

Getting the lowdown on injuries and analyzing the form guide are key steps before making NFL picks. We also put strong emphasis on stats, where a data-led approach often leads to smarter predictions.

Key Chargers vs Raiders stats:

• The 46.5 line hasn’t been covered in 8 of the last 10 Chargers games on the road.
• The 46.5 line hasn’t been covered in 13 of the last 20 Chargers games.
• The 46.5 line hasn’t been covered in 4 of the last 5 Raiders games.
• The 46.5 line hasn’t been covered in 6 of the last 10 Raiders games.

Under 46.5 Probability

According to the best NFL betting sites, there’s a 54.1% likelihood of our pick delivering a return. After careful examination, our analysts calculate this probability to be closer to 60%. This is why we regard this as a value bet.

For a larger payout, many bettors will include their Under pick on the Totals with other selections. A Bet Builder is perfect for combining all your predictions.

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Our Game Prediction

Under 46.5 Points @ -118 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (04:26, 14 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Ladd McConkey Anytime TD +135

Ladd McConkey (Chargers) can be backed at +135 to reach the end zone. We’ll have a play on this Anytime Touchdown Scorer bet, which could hopefully result in him taking it to the house.

Latest Ladd McConkey Player Prop Odds

Touchdown

Anytime

+146

First

+700

Receiving Yards

Over 75.5

-112

Under 75.5

-112

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Brock Bowers Under 61.5 Receiving Yards -114

Brock Bowers (Raiders) is available at -114 to end with fewer than 61.5 receiving yards. He may fall short of the Player Receiving Yards line, making this prop bet a strong pick.

Latest Brock Bowers Player Prop Odds

Touchdown

Anytime

+200

First

+1100

Receiving Yards

Over 51.5

-112

Under 51.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Chargers 27 - 14 Raiders

If you want to achieve a big return from your stake, then it’s worth checking out the correct score lines. The Chargers to claim a 27-14 victory is available at huge odds.

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Chargers vs Raiders Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Los Angeles Chargers have the shortest price to win this game, with the sportsbooks giving them a 66% probability due to their -192 Moneyline betting odds. For those wanting to back Las Vegas Raiders, you will find +162 about the underdogs.

The spread is calculated to be 3.5, while total points comes in at 46.5. NFL fans regularly enjoy the opportunity to bet on the Totals. Those expecting a low total can back Under 46.5 at -110.

There’s no shortage of betting opportunities when it comes to the National Football League. The top sportsbooks offer a wide variety of game lines and team props for each matchup, so be sure to explore both the pre-game and in-game markets before making your pick.

Moneyline

Chargers

-192

Raiders

+162

Point Spread

Chargers -3.5

-110

Raiders +3.5

-110

Total Points

Under 46.5

-110

Over 46.5

-110

There’s the chance to back Omarion Hampton at +490 to be the First Touchdown Scorer. He’s the favorite and available at similar odds to record the last TD instead.

Touchdown

Omarion Hampton (Chargers)

First TD

+490

Anytime TD

-104

Ashton Jeanty (Raiders)

First TD

+550

Anytime TD

-104

Ladd McConkey (Chargers)

First TD

+700

Anytime TD

+146

Jakobi Meyers (Raiders)

First TD

+1000

Anytime TD

+180

Brock Bowers (Raiders)

First TD

+1100

Anytime TD

+200

Keenan Allen (Chargers)

First TD

+1100

Anytime TD

+235

Quentin Johnston (Chargers)

First TD

+1200

Anytime TD

+240

Najee Harris (Chargers)

First TD

+1500

Anytime TD

+285

Michael Mayer (Raiders)

First TD

+2000

Anytime TD

+320

Tre Tucker (Raiders)

First TD

+2000

Anytime TD

+420

Tyler Conklin (Chargers)

First TD

+2200

Anytime TD

+520

Dont'e Thornton Jr. (Raiders)

First TD

+2500

Anytime TD

+470

Justin Herbert (Chargers)

First TD

+2700

Anytime TD

+540

Will Dissly (Chargers)

First TD

+3500

Anytime TD

+600

Geno Smith (Raiders)

First TD

+3500

Anytime TD

+800

KeAndre Lambert-Smith (Chargers)

First TD

+5500

Anytime TD

+900

Raheem Mostert (Raiders)

First TD

+6000

Anytime TD

+1060

Zamir White (Raiders)

First TD

+6000

Anytime TD

+1060

Tre Harris (Chargers)

First TD

+7500

Anytime TD

+1100

Jack Bech (Raiders)

First TD

+8000

Anytime TD

+1400

Justin Shorter (Raiders)

First TD

+8000

Anytime TD

+1400

Ian Thomas (Raiders)

First TD

+8000

Anytime TD

+1400

Tucker Fisk (Chargers)

First TD

+10000

Anytime TD

+1700

Scott Matlock (Chargers)

First TD

+10000

Anytime TD

+1700

Oronde Gadsden II (Chargers)

First TD

+10000

Anytime TD

+1700

Hassan Haskins (Chargers)

First TD

+10000

Anytime TD

+1400

Derius Davis (Chargers)

First TD

+10000

Anytime TD

+1500

Dylan Laube (Raiders)

First TD

+10000

Anytime TD

+1800

Receiving Yards

Ladd McConkey (Chargers)

Over 75.5

-112

Under 75.5

-112

Jakobi Meyers (Raiders)

Over 67.5

-112

Under 67.5

-112

Keenan Allen (Chargers)

Over 53.5

-112

Under 53.5

-112

Brock Bowers (Raiders)

Over 51.5

-112

Under 51.5

-112

Quentin Johnston (Chargers)

Over 43.5

-112

Under 43.5

-112

Tre Tucker (Raiders)

Over 31.5

-112

Under 31.5

-112

Dont'e Thornton Jr. (Raiders)

Over 27.5

-112

Under 27.5

-112

Ashton Jeanty (Raiders)

Over 15.5

-112

Under 15.5

-112

Omarion Hampton (Chargers)

Over 13.5

-112

Under 13.5

-112

Tyler Conklin (Chargers)

Over 12.5

-112

Under 12.5

-112

Rushing Yards

Ashton Jeanty (Raiders)

Over 66.5

-112

Under 66.5

-112

Omarion Hampton (Chargers)

Over 57.5

-112

Under 57.5

-112

Najee Harris (Chargers)

Over 17.5

-112

Under 17.5

-112

Justin Herbert (Chargers)

Over 16.5

-112

Under 16.5

-112

Geno Smith (Raiders)

Over 10.5

-112

Under 10.5

-112

Passing Yards

Justin Herbert (Chargers)

Over 259.5

-112

Under 259.5

-112

Geno Smith (Raiders)

Over 246.5

-112

Under 246.5

-112

You don’t have to wait for the final outcome when it comes to NFL micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Latest regular season and playoff games stats.

Los Angeles Chargers Stats

Las Vegas Raiders Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• -3 Betting Line: Have covered the spread in 6 of the last 10 games
• -3 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +3 Betting Line: Have covered the spread in 4 of the last 10 games
• +3 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 49.10 pts in the previous 10 games
• Game Totals on the Road: An average of 37.80 pts in the previous 10 games on the road
• Over 46.5: Covered in 7 of the previous 10 games
• Over 46.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 25.50 pts and allowed 23.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 22.10 pts and allowed 15.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 42.20 pts in the previous 10 games
• Game Totals at Home: An average of 47.00 pts in the previous 10 home games
• Over 46.5: Covered in 4 of the previous 10 games
• Over 46.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 18.50 pts and allowed 23.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 23.20 pts and allowed 23.80 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 333.70 Yds. Allowed 357.10 Yds
• Rushing Yards: Gained 96.10 Yds. Allowed 126.80 Yds
• Passing Yards: Gained 237.60 Yds. Allowed 230.30 Yds
• Total Touchdowns: Scored 2.60 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 20.20. Allowed 19.80
• Total Turnovers: Committed 0.90. Committed by opponents 1.10
• Total Penalties: Committed 5.60. Committed by opponents 7.00
• Penalty Yards: Lost 41.60 Yds. Gained 65.50 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 323.70 Yds. Allowed 344.70 Yds
• Rushing Yards: Gained 78.10 Yds. Allowed 100.80 Yds
• Passing Yards: Gained 245.70 Yds. Allowed 243.90 Yds
• Total Touchdowns: Scored 1.80 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 2.00 TD
• Total 1st Downs: Picked up 19.10. Allowed 19.50
• Total Turnovers: Committed 1.30. Committed by opponents 1.00
• Total Penalties: Committed 5.80. Committed by opponents 6.90
• Penalty Yards: Lost 52.20 Yds. Gained 49.70 Yds

Last 10 Games on the Road

• Total Yards: Gained 324.10 Yds. Allowed 296.10 Yds
• Rushing Yards: Gained 104.70 Yds. Allowed 108.90 Yds
• Passing Yards: Gained 219.40 Yds. Allowed 187.20 Yds
• Total Touchdowns: Scored 2.20 TD. Allowed 1.60 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.00 TD
• Total 1st Downs: Picked up 18.60. Allowed 17.80
• Total Turnovers: Committed 0.90. Committed by opponents 1.70
• Total Penalties: Committed 5.20. Committed by opponents 5.40
• Penalty Yards: Lost 38.30 Yds. Gained 46.40 Yds

Last 10 Home Games

• Total Yards: Gained 303.50 Yds. Allowed 328.40 Yds
• Rushing Yards: Gained 79.20 Yds. Allowed 106.80 Yds
• Passing Yards: Gained 224.30 Yds. Allowed 221.60 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 18.40. Allowed 19.00
• Total Turnovers: Committed 1.20. Committed by opponents 1.10
• Total Penalties: Committed 4.60. Committed by opponents 6.40
• Penalty Yards: Lost 39.60 Yds. Gained 48.20 Yds

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