Los Angeles Chargers
American Football NFL MetLife Stadium Sun 28 Sep 13:00
New York Giants
  1. Prediction
  2. Bet Builder
  3. Odds
  4. Player Props
  5. Stats
  6. Live Stream
  7. Team News
  8. Lineups
  9. Injuries
  10. Standings

NFL Betting Preview: Chargers vs Giants

The Los Angeles Chargers face the New York Giants in this NFL Week 4 matchup at MetLife Stadium, with kickoff scheduled for 13:00 on Sunday 28 September. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Find Out Why We’re Siding With Chargers

Our betting prediction is for the Chargers to cover the appealing -6.5 line against the Giants. They should be able to win by a more comfortable margin and odds of -110 are available on the spread.

Trusting our spread call? Learn more about BetMGM in our expert review, then unlock the best promo code before you make your move.

Chargers Claimed 37-21 Victory in Last H2H

Los Angeles Chargers claimed a home victory in their previous game. A 23-20 triumph against Denver Broncos at SoFi Stadium made it three straight wins. The Chargers moved the ball for 376 yards, with 270 through the air and 106 on the ground. They picked up 29 first downs to go along with two touchdowns.

New York Giants have lost on their last three outings. In a recent home game at MetLife Stadium, they were turned over 22-9 by Kansas City Chiefs. The Giants recorded 281 yards, with 151 through the air and 130 on the ground. They picked up 19 first downs and found the end zone once.

Head-to-Head Statistics

The Chargers won the last matchup between the pair. Enjoying a 37-21 triumph when facing the Giants at SoFi Stadium.

Quarterbacks

Chargers vs Giants Prediction & Picks

We dive into the best Chargers vs Giants betting angles, including an expert match prediction, correct score forecast, top player prop bets and a value-focused bet builder.

Game Prediction

Back the Chargers against the spread, with a generous betting line of -6.5 that the favorites get the job done in this NFL matchup. There are odds of -110 that are currently on offer for this value pick.

We track all injuries that could impact each franchise before making our NFL predictions. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the action.

Key Chargers vs Giants stats:

  • The -6.5 line has been covered by Chargers in 3 of their last 5 games on the road.
  • The +6.5 line hasn’t been covered by Giants in 7 of their last 10 games.
  • The +6.5 line hasn’t been covered by Giants in 2 of their last 3 games this season.

Chargers -6.5 Probability

The top NFL sportsbooks make it a 52.4% chance that our pick is settled as a winner. However, we have this figure between 55-60% based on our in-depth research. It’s the reason why we are recommending this bet.

Looking for Bigger Odds?

There’s the option to move the line for your spread pick and this enables bettors to get bigger odds. If you’re prepared for additional risk, you can get more bang for your buck.

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Best Bet

Chargers -6.5 @ -110 Watch Live Bet Now BetMGM logo
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Published 19:26, 26 September 2025

Player Prop Picks

Top Pick: Jaxson Dart Under 189.5 Passing Yards -114 BetMGM logo

Jaxson Dart (Giants) is priced at -114 to have less than 189.5 passing yards. There’s no reason to doubt our instinct, so we’ll bet on him falling short of the QB Passing Yards line.

Latest Jaxson Dart Player Prop Odds

Devin Singletary Under 15.5 Rushing Yards -114 BetMGM logo

Devin Singletary (Giants) is priced at -114 to record fewer than 15.5 rushing yards. We're confident he’ll fall short of the Player Rushing Yards line, so we're backing the Under.

Latest Devin Singletary Player Prop Odds

Same Game Parlay Picks

Spread Chargers -6.5
Totals Over 43.5
Passing Yards Jaxson Dart Under 189.5

Take a same game parlay that incorporates Chargers to cover the -6.5 spread along with Over 43.5 points. We’ve also gone for Jaxson Dart (Giants) to have Under 189.5 passing yards.

A same game parlay is a fantastic way of cheering on different picks within the same football game. You can predict a number of outcomes and get bigger odds than a single bet. The odds can combine to great effect.

T&C apply. Gamble responsibly 18+

Correct Score Prediction

Chargers Chargers logo 31 - 17 Giants logo Giants

There’s the chance to bet on the Chargers in lots of different ways and this includes predicting the correct winning score. We’ll go for a 31-17 victory in their favor.

Chargers vs Giants Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Think Chargers Likeliest to Win

With a 74% chance of securing victory, Los Angeles Chargers are favorites for this game and the sportsbooks have them at betting odds of -278. At +230, New York Giants are regarded as having a lower probability of winning.

The spread is 6.5 and the total points line is currently 43.5. A Total bet is always available and can often provide value selections. There’s the chance to back Under 43.5 at -110.

The good news is that you can access a wide range of game lines and team props for every National Football League matchup. The best betting apps offer a great selection of pre-game and in-game wagering options.

Omarion Hampton Favorite to Be First TD Scorer

The First Touchdown Scorer favorite is Omarion Hampton at +470. Similar odds can be found if you’re interested in this player to register the final TD.

Touchdown

Omarion Hampton (Chargers)
First TD
+470
Anytime TD
-120
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Cam Skattebo (Giants)
First TD
+600
Anytime TD
-100
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Keenan Allen (Chargers)
First TD
+800
Anytime TD
+160
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Ladd McConkey (Chargers)
First TD
+850
Anytime TD
+180
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Receiving Yards

Ladd McConkey (Chargers)
Over 64.5
-114
Under 64.5
-114
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Malik Nabers (Giants)
Over 63.5
-114
Under 63.5
-114
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Quentin Johnston (Chargers)
Over 51.5
-114
Under 51.5
-114
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Keenan Allen (Chargers)
Over 50.5
-114
Under 50.5
-114
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Rushing Yards

Omarion Hampton (Chargers)
Over 70.5
-114
Under 70.5
-114
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Cam Skattebo (Giants)
Over 54.5
-114
Under 54.5
-114
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Justin Herbert (Chargers)
Over 17.5
-114
Under 17.5
-114
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Passing Yards

Best Betting Offers
MetLife Stadium
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Giants Record Shows Nine Home Defeats in Last Ten Matches

The Giants are 1-9 in their last 10 home games, posting 13.90 points per contest while yielding 25.40.

The Chargers have gone 6-4 across their last 10 games away from home, averaging 21.50 points on offense and surrendering 16.30 on defense.

Last 10 Games W-L P PF PA O43.5 U43.5
Giants logo Giants Home Stats 1-9 39.30 13.90 25.40 3 7
Chargers logo Chargers Away Stats 6-4 37.80 21.50 16.30 3 7
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O43.5 = Games Over 43.5 Points
  • U43.5 = Games Under 43.5 Points
Team Stats

Latest regular season and playoff games stats.

Los Angeles Chargers logo Los Angeles Chargers Stats
New York Giants logo New York Giants Stats
Moneyline
  • 7 wins and 3 defeats in the last 10 games
  • 6 wins and 4 defeats in the last 10 games on the road
Moneyline
  • 1 win and 9 defeats in the last 10 games
  • 1 win and 9 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points
Game Stats
Last 10 Games
Game Stats
Last 10 Games
Last 10 Games on the Road
Last 10 Home Games

Live Streaming

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Team News

Los Angeles Chargers Injuries

Type
Name
Info
Mekhi Becton
Concussion
Bradley Bozeman
Back
Junior Colson
Shoulder
Derius Davis
Knee
Will Dissly
Knee
Josh Fuga
Undisclosed
Josh Harris
Undisclosed
Najee Harris
Achilles
Deane Leonard
Leg
Khalil Mack
Elbow
Elijah Molden
Hamstring
Jordan Oladokun
Undisclosed
Denzel Perryman
Ankle
Eric Rogers
Undisclosed
Rashawn Slater
Kneecap
Savion Washington
Undisclosed
Mike Williams
Undisclosed

New York Giants Injuries

Type
Name
Info
Chris Board
Chest
Victor Dimukeje
Pectoral
Joshua Ezeudu
Undisclosed
Da'Quan Felton
Undisclosed
Bryce Ford-Wheaton
Achilles
Graham Gano
Groin
Chauncey Golston
Ankle
Eric Gray
Undisclosed
Anthony Johnson
Undisclosed
Micah McFadden
Foot
T.J. Moore
Upper Leg
Rakeem Nunez-Roches
Foot
Rico Payton
Undisclosed
Tyrone Tracy
Shoulder

Previous Los Angeles Chargers Lineups

21 Sep NFL
Broncos 20-23 Chargers
15 Sep NFL
Chargers 20-9 Raiders
05 Sep NFL
Chiefs 21-27 Chargers
11 Jan NFL Playoffs
Chargers 12-32 Texans
05 Jan NFL
Chargers 34-20 Raiders
28 Dec NFL
Chargers 40-7 Patriots
19 Dec NFL
Broncos 27-34 Chargers
15 Dec NFL
Buccaneers 40-17 Chargers
08 Dec NFL
Chargers 17-19 Chiefs
01 Dec NFL
Chargers 17-13 Falcons

Previous New York Giants Lineups

21 Sep NFL
Chiefs 22-9 Giants
14 Sep NFL
Giants 37-40 Cowboys
07 Sep NFL
Giants 6-21 Commanders
05 Jan NFL
Giants 13-20 Eagles
29 Dec NFL
Colts 33-45 Giants
22 Dec NFL
Giants 7-34 Falcons
15 Dec NFL
Ravens 35-14 Giants
08 Dec NFL
Saints 14-11 Giants
28 Nov NFL
Giants 20-27 Cowboys
24 Nov NFL
Buccaneers 30-7 Giants

NFL Standings Select Season

AFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 3 0 0 1.000 102 71 31 2-0-0 1-0-0 2-0-0 3-0-0 3-0-0 3W
Patriots 1 2 0 0.333 60 68 -8 0-2-0 1-0-0 1-0-0 1-2-0 1-2-0 1L
Jets 0 3 0 0.000 69 93 -24 0-2-0 0-1-0 0-1-0 0-2-0 0-3-0 3L
Dolphins 0 3 0 0.000 56 97 -41 0-1-0 0-2-0 0-2-0 0-3-0 0-3-0 3L
AFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bengals 2 1 0 0.667 58 91 -33 1-0-0 1-1-0 1-0-0 2-0-0 2-1-0 1L
Steelers 2 1 0 0.667 72 77 -5 0-1-0 2-0-0 0-0-0 2-0-0 2-1-0 1W
Ravens 1 2 0 0.333 111 96 15 1-1-0 0-1-0 1-0-0 1-1-0 1-2-0 1L
Browns 1 2 0 0.333 46 68 -22 1-1-0 0-1-0 0-2-0 0-2-0 1-2-0 1W
AFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Colts 3 0 0 1.000 103 56 47 2-0-0 1-0-0 1-0-0 3-0-0 3-0-0 3W
Jaguars 2 1 0 0.667 70 51 19 2-0-0 0-1-0 1-0-0 1-1-0 2-1-0 1W
Texans 0 3 0 0.000 38 51 -13 0-1-0 0-2-0 0-1-0 0-1-0 0-3-0 3L
Titans 0 3 0 0.000 51 94 -43 0-2-0 0-1-0 0-1-0 0-2-0 0-3-0 3L
AFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Chargers 3 0 0 1.000 70 50 20 2-0-0 1-0-0 3-0-0 3-0-0 3-0-0 3W
Raiders 1 2 0 0.333 53 74 -21 0-1-0 1-1-0 0-1-0 1-1-0 1-2-0 2L
Broncos 1 2 0 0.333 68 64 4 1-0-0 0-2-0 0-1-0 1-2-0 1-2-0 2L
Chiefs 1 2 0 0.333 60 56 4 0-1-0 1-1-0 0-1-0 0-1-0 1-2-0 1W
NFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Eagles 3 0 0 1.000 77 63 14 2-0-0 1-0-0 1-0-0 2-0-0 3-0-0 3W
Commanders 2 1 0 0.667 80 57 23 2-0-0 0-1-0 1-0-0 1-1-0 2-1-0 1W
Cowboys 1 2 0 0.333 74 92 -18 1-0-0 0-2-0 1-1-0 1-2-0 1-2-0 1L
Giants 0 3 0 0.000 52 83 -31 0-1-0 0-2-0 0-2-0 0-2-0 0-3-0 3L
NFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Packers 2 1 0 0.667 64 44 20 2-0-0 0-1-0 1-0-0 2-0-0 2-1-0 1L
Vikings 2 1 0 0.667 81 56 25 1-1-0 1-0-0 1-0-0 1-1-0 2-1-0 1W
Lions 2 1 0 0.667 103 78 25 1-0-0 1-1-0 1-1-0 1-1-0 2-1-0 2W
Bears 1 2 0 0.333 76 93 -17 1-1-0 0-1-0 0-2-0 1-2-0 1-2-0 1W
NFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Buccaneers 3 0 0 1.000 72 66 6 1-0-0 2-0-0 1-0-0 1-0-0 3-0-0 3W
Panthers 1 2 0 0.333 62 53 9 1-0-0 0-2-0 1-0-0 1-1-0 1-2-0 1W
Falcons 1 2 0 0.333 42 59 -17 0-1-0 1-1-0 0-2-0 1-2-0 1-2-0 1L
Saints 0 3 0 0.000 47 90 -43 0-2-0 0-1-0 0-0-0 0-3-0 0-3-0 3L
NFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
49ers 3 0 0 1.000 59 49 10 1-0-0 2-0-0 2-0-0 3-0-0 3-0-0 3W
Cardinals 2 2 0 0.500 82 74 8 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 2L
Seahawks 3 1 0 0.750 111 67 44 1-1-0 2-0-0 1-1-0 2-1-0 3-1-0 3W
Rams 2 1 0 0.667 73 61 12 1-0-0 1-1-0 0-0-0 0-1-0 2-1-0 1L
AFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Chargers 3 0 0 1.000 70 50 20 2-0-0 1-0-0 3-0-0 3-0-0 3-0-0 3W
Colts 3 0 0 1.000 103 56 47 2-0-0 1-0-0 1-0-0 3-0-0 3-0-0 3W
Bills 3 0 0 1.000 102 71 31 2-0-0 1-0-0 2-0-0 3-0-0 3-0-0 3W
Bengals 2 1 0 0.667 58 91 -33 1-0-0 1-1-0 1-0-0 2-0-0 2-1-0 1L
Steelers 2 1 0 0.667 72 77 -5 0-1-0 2-0-0 0-0-0 2-0-0 2-1-0 1W
Jaguars 2 1 0 0.667 70 51 19 2-0-0 0-1-0 1-0-0 1-1-0 2-1-0 1W
Raiders 1 2 0 0.333 53 74 -21 0-1-0 1-1-0 0-1-0 1-1-0 1-2-0 2L
Ravens 1 2 0 0.333 111 96 15 1-1-0 0-1-0 1-0-0 1-1-0 1-2-0 1L
Broncos 1 2 0 0.333 68 64 4 1-0-0 0-2-0 0-1-0 1-2-0 1-2-0 2L
Patriots 1 2 0 0.333 60 68 -8 0-2-0 1-0-0 1-0-0 1-2-0 1-2-0 1L
Browns 1 2 0 0.333 46 68 -22 1-1-0 0-1-0 0-2-0 0-2-0 1-2-0 1W
Chiefs 1 2 0 0.333 60 56 4 0-1-0 1-1-0 0-1-0 0-1-0 1-2-0 1W
Titans 0 3 0 0.000 51 94 -43 0-2-0 0-1-0 0-1-0 0-2-0 0-3-0 3L
Dolphins 0 3 0 0.000 56 97 -41 0-1-0 0-2-0 0-2-0 0-3-0 0-3-0 3L
Jets 0 3 0 0.000 69 93 -24 0-2-0 0-1-0 0-1-0 0-2-0 0-3-0 3L
Texans 0 3 0 0.000 38 51 -13 0-1-0 0-2-0 0-1-0 0-1-0 0-3-0 3L
NFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Eagles 3 0 0 1.000 77 63 14 2-0-0 1-0-0 1-0-0 2-0-0 3-0-0 3W
49ers 3 0 0 1.000 59 49 10 1-0-0 2-0-0 2-0-0 3-0-0 3-0-0 3W
Buccaneers 3 0 0 1.000 72 66 6 1-0-0 2-0-0 1-0-0 1-0-0 3-0-0 3W
Seahawks 3 1 0 0.750 111 67 44 1-1-0 2-0-0 1-1-0 2-1-0 3-1-0 3W
Packers 2 1 0 0.667 64 44 20 2-0-0 0-1-0 1-0-0 2-0-0 2-1-0 1L
Cardinals 2 2 0 0.500 82 74 8 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 2L
Vikings 2 1 0 0.667 81 56 25 1-1-0 1-0-0 1-0-0 1-1-0 2-1-0 1W
Commanders 2 1 0 0.667 80 57 23 2-0-0 0-1-0 1-0-0 1-1-0 2-1-0 1W
Lions 2 1 0 0.667 103 78 25 1-0-0 1-1-0 1-1-0 1-1-0 2-1-0 2W
Rams 2 1 0 0.667 73 61 12 1-0-0 1-1-0 0-0-0 0-1-0 2-1-0 1L
Panthers 1 2 0 0.333 62 53 9 1-0-0 0-2-0 1-0-0 1-1-0 1-2-0 1W
Falcons 1 2 0 0.333 42 59 -17 0-1-0 1-1-0 0-2-0 1-2-0 1-2-0 1L
Bears 1 2 0 0.333 76 93 -17 1-1-0 0-1-0 0-2-0 1-2-0 1-2-0 1W
Cowboys 1 2 0 0.333 74 92 -18 1-0-0 0-2-0 1-1-0 1-2-0 1-2-0 1L
Saints 0 3 0 0.000 47 90 -43 0-2-0 0-1-0 0-0-0 0-3-0 0-3-0 3L
Giants 0 3 0 0.000 52 83 -31 0-1-0 0-2-0 0-2-0 0-2-0 0-3-0 3L
NFL Team W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 3 0 0 1.000 102 71 31 2-0-0 1-0-0 2-0-0 3-0-0 3-0-0 3W
Colts 3 0 0 1.000 103 56 47 2-0-0 1-0-0 1-0-0 3-0-0 3-0-0 3W
Chargers 3 0 0 1.000 70 50 20 2-0-0 1-0-0 3-0-0 3-0-0 3-0-0 3W
Eagles 3 0 0 1.000 77 63 14 2-0-0 1-0-0 1-0-0 2-0-0 3-0-0 3W
49ers 3 0 0 1.000 59 49 10 1-0-0 2-0-0 2-0-0 3-0-0 3-0-0 3W
Buccaneers 3 0 0 1.000 72 66 6 1-0-0 2-0-0 1-0-0 1-0-0 3-0-0 3W
Seahawks 3 1 0 0.750 111 67 44 1-1-0 2-0-0 1-1-0 2-1-0 3-1-0 3W
Bengals 2 1 0 0.667 58 91 -33 1-0-0 1-1-0 1-0-0 2-0-0 2-1-0 1L
Lions 2 1 0 0.667 103 78 25 1-0-0 1-1-0 1-1-0 1-1-0 2-1-0 2W
Packers 2 1 0 0.667 64 44 20 2-0-0 0-1-0 1-0-0 2-0-0 2-1-0 1L
Jaguars 2 1 0 0.667 70 51 19 2-0-0 0-1-0 1-0-0 1-1-0 2-1-0 1W
Rams 2 1 0 0.667 73 61 12 1-0-0 1-1-0 0-0-0 0-1-0 2-1-0 1L
Vikings 2 1 0 0.667 81 56 25 1-1-0 1-0-0 1-0-0 1-1-0 2-1-0 1W
Steelers 2 1 0 0.667 72 77 -5 0-1-0 2-0-0 0-0-0 2-0-0 2-1-0 1W
Commanders 2 1 0 0.667 80 57 23 2-0-0 0-1-0 1-0-0 1-1-0 2-1-0 1W
Cardinals 2 2 0 0.500 82 74 8 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 2L
Falcons 1 2 0 0.333 42 59 -17 0-1-0 1-1-0 0-2-0 1-2-0 1-2-0 1L
Ravens 1 2 0 0.333 111 96 15 1-1-0 0-1-0 1-0-0 1-1-0 1-2-0 1L
Panthers 1 2 0 0.333 62 53 9 1-0-0 0-2-0 1-0-0 1-1-0 1-2-0 1W
Bears 1 2 0 0.333 76 93 -17 1-1-0 0-1-0 0-2-0 1-2-0 1-2-0 1W
Browns 1 2 0 0.333 46 68 -22 1-1-0 0-1-0 0-2-0 0-2-0 1-2-0 1W
Cowboys 1 2 0 0.333 74 92 -18 1-0-0 0-2-0 1-1-0 1-2-0 1-2-0 1L
Broncos 1 2 0 0.333 68 64 4 1-0-0 0-2-0 0-1-0 1-2-0 1-2-0 2L
Chiefs 1 2 0 0.333 60 56 4 0-1-0 1-1-0 0-1-0 0-1-0 1-2-0 1W
Raiders 1 2 0 0.333 53 74 -21 0-1-0 1-1-0 0-1-0 1-1-0 1-2-0 2L
Patriots 1 2 0 0.333 60 68 -8 0-2-0 1-0-0 1-0-0 1-2-0 1-2-0 1L
Texans 0 3 0 0.000 38 51 -13 0-1-0 0-2-0 0-1-0 0-1-0 0-3-0 3L
Dolphins 0 3 0 0.000 56 97 -41 0-1-0 0-2-0 0-2-0 0-3-0 0-3-0 3L
Saints 0 3 0 0.000 47 90 -43 0-2-0 0-1-0 0-0-0 0-3-0 0-3-0 3L
Giants 0 3 0 0.000 52 83 -31 0-1-0 0-2-0 0-2-0 0-2-0 0-3-0 3L
Jets 0 3 0 0.000 69 93 -24 0-2-0 0-1-0 0-1-0 0-2-0 0-3-0 3L
Titans 0 3 0 0.000 51 94 -43 0-2-0 0-1-0 0-1-0 0-2-0 0-3-0 3L