Rams vs Cardinals Prediction, Picks & Odds | 07 Dec 2025

NFL Betting Preview: Rams vs Cardinals

The Los Angeles Rams go up against the Arizona Cardinals at State Farm Stadium, with kickoff scheduled for 16:25 on Sunday, December 7.

We’re bullish about the Rams on the spread at -8.5. The favorites should be able to win by a comfortable margin against the Cardinals and you can get -105.

Rolling with our spread angle? Read our comprehensive BetMGM review, then secure the best promo code before placing your wager.

Los Angeles Rams were beaten in their previous game and this was on the road at Bank of America Stadium. Carolina Panthers claimed a 31-28 win. The Rams recorded 379 yards, breaking down to 227 passing and 152 rushing yards. The offense produced 22 first downs and scored 4 touchdowns, split between 2 by pass and 2 by run.

Arizona Cardinals have suffered defeat in their last five home games. Most recently, they lost 20-17 on the road at Raymond James Stadium against Tampa Bay Buccaneers. The Cardinals totaled 386 yards, split between 291 passing and 95 rushing yards. The offense produced 22 first downs and scored two touchdowns.

Head-to-Head Statistics

The Rams beat the Cardinals in their last head-to-head matchup. It was a 13-9 scoreline at SoFi Stadium. The past 10 clashes between these teams have seen seven Rams wins.

Quarterbacks

Matthew Stafford

259.5 Passing Yards

Over -114

Under -114

Jacoby Brissett

250.5 Passing Yards

Over -114

Under -114

Rams vs Cardinals Prediction & Picks

Our Rams vs Cardinals betting outlook has it all, including a trusted match forecast, our predicted score, top player prop picks and a hand-picked bet builder.

Game Prediction

There’s an attractive line of -8.5 when it comes to the Rams for this NFL matchup. The -105 that the favorites cover the spread has lots of juice and our pick is that they will make it happen.

The NFL handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our picks. We combine this insight with up-to-date stats for sharper predictions.

Key Rams vs Cardinals stats:

• The -8.5 line has been covered by Rams in 4 of their last 6 games on the road this season.
• The -8.5 line has been covered by Rams in 3 of their last 5 games.

Rams -8.5 Probability

The best betting apps imply that our pick has a 51.3% chance of winning. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. The wager can be recommended for this precise reason.

A Bet Builder provides you with the opportunity to combine the Rams on the spread with other selections. For every additional pick, the odds are boosted.

Thinking of placing a bet? Make sure to check our guide first — it’s full of the latest offers and welcome bonuses worth claiming.

Our Game Prediction

Rams -8.5 @ -105 Bet Now

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Player Prop Picks

Top Pick: Jacoby Brissett Under 250.5 Passing Yards -114

Jacoby Brissett (Cardinals) can be backed at -114 to finish with fewer than 250.5 passing yards. There’s no reason to doubt our instinct, so we’ll bet on him falling short of the QB Passing Yards line.

Latest Jacoby Brissett Player Prop Odds

Touchdown

Anytime

+750

First

+3000

Passing Yards

Over 250.5

-114

Under 250.5

-114

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Davante Adams Anytime TD -161

Davante Adams (Rams) is available at -161 to reach the goal line. There are appealing odds on offer for this Anytime Touchdown Scorer pick, and we believe it's an attractive wager for him to punch it in.

Latest Davante Adams Player Prop Odds

Touchdown

Anytime

-161

First

+440

Receiving Yards

Over 52.5

-114

Under 52.5

-114

Correct Score Prediction

Rams 31 - 20 Cardinals

There are lots of different betting angles including the chance to back the Rams on the correct score lines. For example, a 31-20 win in their favor is available at massive odds.

Rams vs Cardinals Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Los Angeles Rams have short betting odds and they’re overwhelming -435 favorites for this game. This means the sportsbooks give them a 81% chance of winning. At +340, Arizona Cardinals are regarded as having a lower probability of winning.

The spread is 8.5 and the total points line is currently 47.5. Having a wager on the Totals is one of the most popular NFL bets. Those that want to back Under 47.5 can find odds of -104 available.

The top NFL sportsbooks offer a huge selection of game lines and team props when it comes to this popular league. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Rams

-435

Cardinals

+340

Point Spread

Rams -8.5

-105

Cardinals +8.5

-115

Total Points

Under 47.5

-104

Over 47.5

-118

Davante Adams is the market leader to be First TD Scorer at +440. Alternatively, there’s the chance to back him to register a touchdown at any stage at -161.

Touchdown

Davante Adams (Rams)

First TD

+440

Anytime TD

-161

Puka Nacua (Rams)

First TD

+500

Anytime TD

-115

Kyren Williams (Rams)

First TD

+700

Anytime TD

+105

Trey McBride (Cardinals)

First TD

+750

Anytime TD

+115

Colby Parkinson (Rams)

First TD

+1000

Anytime TD

+180

Michael Wilson (Cardinals)

First TD

+1100

Anytime TD

+175

Bam Knight (Cardinals)

First TD

+1200

Anytime TD

+185

Marvin Harrison Jr. (Cardinals)

First TD

+1400

Anytime TD

+175

Blake Corum (Rams)

First TD

+1900

Anytime TD

+290

Emari Demercado (Cardinals)

First TD

+1900

Anytime TD

+300

Michael Carter (Cardinals)

First TD

+2000

Anytime TD

+330

Greg Dortch (Cardinals)

First TD

+2200

Anytime TD

+300

Xavier Smith (Rams)

First TD

+2500

Anytime TD

+390

Xavier Weaver (Cardinals)

First TD

+2700

Anytime TD

+380

Jordan Whittington (Rams)

First TD

+3000

Anytime TD

+480

Jacoby Brissett (Cardinals)

First TD

+3000

Anytime TD

+750

Konata Mumpfield (Rams)

First TD

+3000

Anytime TD

+480

Davis Allen (Rams)

First TD

+3500

Anytime TD

+550

Terrance Ferguson (Rams)

First TD

+4500

Anytime TD

+750

Nick Vannett (Rams)

First TD

+4500

Anytime TD

+750

Andre Baccellia (Cardinals)

First TD

+4500

Anytime TD

+600

Elijah Higgins (Cardinals)

First TD

+5000

Anytime TD

+700

Pharaoh Brown (Cardinals)

First TD

+10000

Anytime TD

+1600

Josiah Deguara (Cardinals)

First TD

+10000

Anytime TD

+1600

Matthew Stafford (Rams)

First TD

+10000

Anytime TD

+2200

Ronnie Rivers (Rams)

First TD

+10000

Anytime TD

+3000

Jarquez Hunter (Rams)

First TD

+10000

Anytime TD

+3000

Corey Kiner (Cardinals)

First TD

+10000

Anytime TD

+2200

Receiving Yards

Puka Nacua (Rams)

Over 92.5

-114

Under 92.5

-114

Trey McBride (Cardinals)

Over 76.5

-114

Under 76.5

-114

Michael Wilson (Cardinals)

Over 66.5

-114

Under 66.5

-114

Davante Adams (Rams)

Over 52.5

-114

Under 52.5

-114

Colby Parkinson (Rams)

Over 27.5

-114

Under 27.5

-114

Rushing Yards

Kyren Williams (Rams)

Over 63.5

-114

Under 63.5

-114

Passing Yards

Matthew Stafford (Rams)

Over 259.5

-114

Under 259.5

-114

Jacoby Brissett (Cardinals)

Over 250.5

-114

Under 250.5

-114

Cardinals Record Shows Five Consecutive Home Defeats

The Cardinals have endured a run of five straight defeats at State Farm Stadium. They have four wins and six losses in the last 10 home games, averaging 26.30 points on offense and surrendering 23.90 on defense.

The Rams are 7-3 in their last 10 games away from home, scoring 25.50 points per contest and conceding 17.60.

The last State Farm Stadium meeting saw the Cardinals beat the Rams 41-10. In their last 6 head-to-head matchups at State Farm Stadium, the Rams have taken five wins compared to one for the Cardinals.

Last 10 Games		W-L	P	PF	PA	O47.5	U47.5
Cardinals Home Stats		4-6	50.20	26.30	23.90	6	4
Rams Away Stats		7-3	43.10	25.50	17.60	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O47.5 = Games Over 47.5 Points
• U47.5 = Games Under 47.5 Points

Latest regular season and playoff games stats.

Los Angeles Rams Stats

Arizona Cardinals Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 1 win and 9 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• -8.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -8.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +8.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +8.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games

Total Points

• Game Totals: An average of 46.90 pts in the previous 10 games
• Game Totals on the Road: An average of 43.10 pts in the previous 10 games on the road
• Over 47.5: Covered in 4 of the previous 10 games
• Over 47.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.70 pts and allowed 18.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 25.50 pts and allowed 17.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 48.60 pts in the previous 10 games
• Game Totals at Home: An average of 50.20 pts in the previous 10 home games
• Over 47.5: Covered in 5 of the previous 10 games
• Over 47.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 21.80 pts and allowed 26.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 26.30 pts and allowed 23.90 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 358.60 Yds. Allowed 326.40 Yds
• Rushing Yards: Gained 114.10 Yds. Allowed 107.10 Yds
• Passing Yards: Gained 244.50 Yds. Allowed 219.30 Yds
• Total Touchdowns: Scored 3.70 TD. Allowed 2.10 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 2.90 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 22.90. Allowed 19.40
• Total Turnovers: Committed 0.90. Committed by opponents 1.70
• Total Penalties: Committed 4.10. Committed by opponents 7.10
• Penalty Yards: Lost 33.70 Yds. Gained 58.60 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 347.80 Yds. Allowed 331.90 Yds
• Rushing Yards: Gained 97.90 Yds. Allowed 119.50 Yds
• Passing Yards: Gained 249.90 Yds. Allowed 212.40 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 21.30. Allowed 20.20
• Total Turnovers: Committed 1.40. Committed by opponents 1.50
• Total Penalties: Committed 6.80. Committed by opponents 5.40
• Penalty Yards: Lost 50.60 Yds. Gained 50.20 Yds

Last 10 Games on the Road

• Total Yards: Gained 335.50 Yds. Allowed 313.40 Yds
• Rushing Yards: Gained 129.10 Yds. Allowed 127.20 Yds
• Passing Yards: Gained 206.40 Yds. Allowed 186.20 Yds
• Total Touchdowns: Scored 3.00 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 0.50 TD
• Passing Touchdowns: Scored 2.10 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 20.90. Allowed 18.10
• Total Turnovers: Committed 0.90. Committed by opponents 1.00
• Total Penalties: Committed 3.50. Committed by opponents 6.80
• Penalty Yards: Lost 30.50 Yds. Gained 56.50 Yds

Last 10 Home Games

• Total Yards: Gained 360.00 Yds. Allowed 334.00 Yds
• Rushing Yards: Gained 110.60 Yds. Allowed 111.40 Yds
• Passing Yards: Gained 249.40 Yds. Allowed 222.60 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 21.80. Allowed 20.50
• Total Turnovers: Committed 1.20. Committed by opponents 1.40
• Total Penalties: Committed 7.30. Committed by opponents 6.60
• Penalty Yards: Lost 57.40 Yds. Gained 57.80 Yds

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