Rams vs Cardinals Prediction, Picks & Odds | 07 Dec 2025

NFL Betting Preview: Rams vs Cardinals

The Los Angeles Rams go up against the Arizona Cardinals at State Farm Stadium, with kickoff scheduled for 16:25 on Sunday, December 7.

We’re bullish about the Rams on the spread at -8.5. The favorites should be able to win by a comfortable margin against the Cardinals and you can get -105.

Rolling with our spread angle? Read our comprehensive BetMGM review, then secure the best promo code before placing your wager.

Los Angeles Rams were beaten in their previous game and this was on the road at Bank of America Stadium. Carolina Panthers claimed a 31-28 win. The Rams recorded 379 yards, breaking down to 227 passing and 152 rushing yards. The offense produced 22 first downs and scored 4 touchdowns, split between 2 by pass and 2 by run.

Arizona Cardinals have suffered defeat in their last five home games. Most recently, they lost 20-17 on the road at Raymond James Stadium against Tampa Bay Buccaneers. The Cardinals totaled 386 yards, split between 291 passing and 95 rushing yards. The offense produced 22 first downs and scored two touchdowns.

Head-to-Head Statistics

The Rams beat the Cardinals in their last head-to-head matchup. It was a 13-9 scoreline at SoFi Stadium. The past 10 clashes between these teams have seen seven Rams wins.

Quarterbacks

Matthew Stafford

261.5 Passing Yards

Over -112

Under -112

Jacoby Brissett

253.5 Passing Yards

Over -112

Under -112

Rams vs Cardinals Prediction & Picks

Our Rams vs Cardinals betting outlook has it all, including a trusted match forecast, our predicted score, top player prop picks and a hand-picked bet builder.

Game Prediction

There’s an attractive line of -8.5 when it comes to the Rams for this NFL matchup. The -105 that the favorites cover the spread has lots of juice and our pick is that they will make it happen.

The NFL handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our picks. We combine this insight with up-to-date stats for sharper predictions.

Key Rams vs Cardinals stats:

• The -8.5 line has been covered by Rams in 4 of their last 6 games on the road this season.
• The -8.5 line has been covered by Rams in 3 of their last 5 games.

Rams -8.5 Probability

The best betting apps imply that our pick has a 51.3% chance of winning. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. The wager can be recommended for this precise reason.

A Bet Builder provides you with the opportunity to combine the Rams on the spread with other selections. For every additional pick, the odds are boosted.

Thinking of placing a bet? Make sure to check our guide first — it’s full of the latest offers and welcome bonuses worth claiming.

Our Game Prediction

Rams -8.5 @ -105 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (22:25, 05 December 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Jacoby Brissett Under 250.5 Passing Yards -114

Jacoby Brissett (Cardinals) can be backed at -114 to finish with fewer than 250.5 passing yards. There’s no reason to doubt our instinct, so we’ll bet on him falling short of the QB Passing Yards line.

Latest Jacoby Brissett Player Prop Odds

Touchdown

Anytime

+750

First

+3500

Passing Yards

Over 253.5

-112

Under 253.5

-112

Rushing Yards

Over 11.5

-112

Under 11.5

-112

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Davante Adams Anytime TD -161

Davante Adams (Rams) is available at -161 to reach the goal line. There are appealing odds on offer for this Anytime Touchdown Scorer pick, and we believe it's an attractive wager for him to punch it in.

Latest Davante Adams Player Prop Odds

Touchdown

Anytime

-169

First

+430

Receiving Yards

Over 59.5

-112

Under 59.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Rams 31 - 20 Cardinals

There are lots of different betting angles including the chance to back the Rams on the correct score lines. For example, a 31-20 win in their favor is available at massive odds.

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Rams vs Cardinals Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Los Angeles Rams have short betting odds and they’re overwhelming -118 favorites for this game. This means the sportsbooks give them a 54% chance of winning. At -102, Arizona Cardinals are regarded as having a lower probability of winning.

The spread is 1.5 and the total points line is currently 47.5. Having a wager on the Totals is one of the most popular NFL bets. Those that want to back Under 47.5 can find odds of -110 available.

The top NFL sportsbooks offer a huge selection of game lines and team props when it comes to this popular league. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Rams

-118

Cardinals

-102

Point Spread

Rams -1.5

-105

Cardinals +1.5

-115

Total Points

Under 47.5

-110

Over 47.5

-110

Davante Adams is the market leader to be First TD Scorer at +430. Alternatively, there’s the chance to back him to register a touchdown at any stage at -169.

Touchdown

Davante Adams (Rams)

First TD

+430

Anytime TD

-169

Kyren Williams (Rams)

First TD

+500

Anytime TD

-135

Puka Nacua (Rams)

First TD

+550

Anytime TD

-105

Trey McBride (Cardinals)

First TD

+800

Anytime TD

+115

Colby Parkinson (Rams)

First TD

+1100

Anytime TD

+200

Michael Wilson (Cardinals)

First TD

+1100

Anytime TD

+175

Bam Knight (Cardinals)

First TD

+1200

Anytime TD

+190

Marvin Harrison Jr. (Cardinals)

First TD

+1400

Anytime TD

+175

Blake Corum (Rams)

First TD

+1600

Anytime TD

+240

Emari Demercado (Cardinals)

First TD

+1900

Anytime TD

+300

Greg Dortch (Cardinals)

First TD

+2200

Anytime TD

+300

Michael Carter (Cardinals)

First TD

+2200

Anytime TD

+330

Xavier Smith (Rams)

First TD

+2200

Anytime TD

+440

Xavier Weaver (Cardinals)

First TD

+2500

Anytime TD

+420

Davis Allen (Rams)

First TD

+3000

Anytime TD

+600

Elijah Higgins (Cardinals)

First TD

+3000

Anytime TD

+500

Jacoby Brissett (Cardinals)

First TD

+3500

Anytime TD

+750

Andre Baccellia (Cardinals)

First TD

+4500

Anytime TD

+500

Jordan Whittington (Rams)

First TD

+6000

Anytime TD

+550

Konata Mumpfield (Rams)

First TD

+6000

Anytime TD

+550

Jalen Brooks (Cardinals)

First TD

+6000

Anytime TD

+600

Trent Sherfield Sr. (Cardinals)

First TD

+6000

Anytime TD

+600

Terrance Ferguson (Rams)

First TD

+7500

Anytime TD

+800

Nick Vannett (Rams)

First TD

+7500

Anytime TD

+800

Matthew Stafford (Rams)

First TD

+8000

Anytime TD

+1600

Pharaoh Brown (Cardinals)

First TD

+10000

Anytime TD

+1700

Josiah Deguara (Cardinals)

First TD

+10000

Anytime TD

+1700

Ronnie Rivers (Rams)

First TD

+10000

Anytime TD

+3000

Jarquez Hunter (Rams)

First TD

+10000

Anytime TD

+3000

Corey Kiner (Cardinals)

First TD

+10000

Anytime TD

+2200

Receiving Yards

Puka Nacua (Rams)

Over 92.5

-112

Under 92.5

-112

Trey McBride (Cardinals)

Over 78.5

-112

Under 78.5

-112

Michael Wilson (Cardinals)

Over 70.5

-112

Under 70.5

-112

Davante Adams (Rams)

Over 59.5

-112

Under 59.5

-112

Colby Parkinson (Rams)

Over 26.5

-112

Under 26.5

-112

Michael Carter (Cardinals)

Over 19.5

-112

Under 19.5

-112

Xavier Weaver (Cardinals)

Over 19.5

-114

Under 19.5

-114

Bam Knight (Cardinals)

Over 17.5

-112

Under 17.5

-112

Elijah Higgins (Cardinals)

Over 15.5

-112

Under 15.5

-112

Xavier Smith (Rams)

Over 14.5

-112

Under 14.5

-112

Kyren Williams (Rams)

Over 10.5

-112

Under 10.5

-112

Davis Allen (Rams)

Over 10.5

-112

Under 10.5

-112

Rushing Yards

Kyren Williams (Rams)

Over 62.5

-112

Under 62.5

-112

Bam Knight (Cardinals)

Over 37.5

-112

Under 37.5

-112

Blake Corum (Rams)

Over 35.5

-112

Under 35.5

-112

Michael Carter (Cardinals)

Over 17.5

-112

Under 17.5

-112

Jacoby Brissett (Cardinals)

Over 11.5

-112

Under 11.5

-112

Passing Yards

Matthew Stafford (Rams)

Over 261.5

-112

Under 261.5

-112

Jacoby Brissett (Cardinals)

Over 253.5

-112

Under 253.5

-112

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Cardinals Record Shows Five Consecutive Home Defeats

The Cardinals have endured a run of five straight defeats at State Farm Stadium. They have four wins and six losses in the last 10 home games, averaging 26.30 points on offense and surrendering 23.90 on defense.

The Rams are 7-3 in their last 10 games away from home, scoring 25.50 points per contest and conceding 17.60.

The last State Farm Stadium meeting saw the Cardinals beat the Rams 41-10. In their last 6 head-to-head matchups at State Farm Stadium, the Rams have taken five wins compared to one for the Cardinals.

Last 10 Games		W-L	P	PF	PA	O47.5	U47.5
Cardinals Home Stats		4-6	50.20	26.30	23.90	6	4
Rams Away Stats		7-3	43.10	25.50	17.60	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O47.5 = Games Over 47.5 Points
• U47.5 = Games Under 47.5 Points

Latest regular season and playoff games stats.

Los Angeles Rams Stats

Arizona Cardinals Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 1 win and 9 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• -8.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -8.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +8.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +8.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games

Total Points

• Game Totals: An average of 46.90 pts in the previous 10 games
• Game Totals on the Road: An average of 43.10 pts in the previous 10 games on the road
• Over 47.5: Covered in 4 of the previous 10 games
• Over 47.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.70 pts and allowed 18.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 25.50 pts and allowed 17.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 48.60 pts in the previous 10 games
• Game Totals at Home: An average of 50.20 pts in the previous 10 home games
• Over 47.5: Covered in 5 of the previous 10 games
• Over 47.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 21.80 pts and allowed 26.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 26.30 pts and allowed 23.90 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 358.60 Yds. Allowed 326.40 Yds
• Rushing Yards: Gained 114.10 Yds. Allowed 107.10 Yds
• Passing Yards: Gained 244.50 Yds. Allowed 219.30 Yds
• Total Touchdowns: Scored 3.70 TD. Allowed 2.10 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 2.90 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 22.90. Allowed 19.40
• Total Turnovers: Committed 0.90. Committed by opponents 1.70
• Total Penalties: Committed 4.10. Committed by opponents 7.10
• Penalty Yards: Lost 33.70 Yds. Gained 58.60 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 347.80 Yds. Allowed 331.90 Yds
• Rushing Yards: Gained 97.90 Yds. Allowed 119.50 Yds
• Passing Yards: Gained 249.90 Yds. Allowed 212.40 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 21.30. Allowed 20.20
• Total Turnovers: Committed 1.40. Committed by opponents 1.50
• Total Penalties: Committed 6.80. Committed by opponents 5.40
• Penalty Yards: Lost 50.60 Yds. Gained 50.20 Yds

Last 10 Games on the Road

• Total Yards: Gained 335.50 Yds. Allowed 313.40 Yds
• Rushing Yards: Gained 129.10 Yds. Allowed 127.20 Yds
• Passing Yards: Gained 206.40 Yds. Allowed 186.20 Yds
• Total Touchdowns: Scored 3.00 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 0.50 TD
• Passing Touchdowns: Scored 2.10 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 20.90. Allowed 18.10
• Total Turnovers: Committed 0.90. Committed by opponents 1.00
• Total Penalties: Committed 3.50. Committed by opponents 6.80
• Penalty Yards: Lost 30.50 Yds. Gained 56.50 Yds

Last 10 Home Games

• Total Yards: Gained 360.00 Yds. Allowed 334.00 Yds
• Rushing Yards: Gained 110.60 Yds. Allowed 111.40 Yds
• Passing Yards: Gained 249.40 Yds. Allowed 222.60 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 21.80. Allowed 20.50
• Total Turnovers: Committed 1.20. Committed by opponents 1.40
• Total Penalties: Committed 7.30. Committed by opponents 6.60
• Penalty Yards: Lost 57.40 Yds. Gained 57.80 Yds

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