Rams vs Eagles Prediction, Picks & Odds | 21 Sep 2025

NFL Betting Preview: Rams vs Eagles

The Los Angeles Rams battle the Philadelphia Eagles in this NFL Week 3 matchup at Lincoln Financial Field, with kickoff scheduled for 13:00 on Sunday, September 21. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

It’s time to go for the Eagles against the spread, especially with an attractive -3.5 line at -104. Our prediction is that this can be comfortably achieved in their meeting with the Rams.

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Los Angeles Rams have won two on the spin, triumphing 33-19 in their previous game. This was on the road against Tennessee Titans at Nissan Stadium. The Rams moved the ball for 439 yards, split between 290 passing and 149 rushing yards. They produced 22 first downs and crossed the goal line 4 times.

Philadelphia Eagles won last time out by a 20-17 scoreline. On the road against Kansas City Chiefs at GEHA Field at Arrowhead Stadium, they made it back-to-back wins. The Eagles moved the ball for 216 yards, with 94 through the air and 122 on the ground. They picked up 16 first downs and found the end zone twice, both times with rushing scores.

Head-to-Head Statistics

The Eagles triumphed 28-22 when they last played the Rams. This head-to-head was played at Lincoln Financial Field. The past 4 games between the teams have seen the Eagles win three times.

Quarterbacks

Matthew Stafford

228.5 Passing Yards

Over -112

Under -112

Jalen Hurts

192.5 Passing Yards

Over -112

Under -112

Rams vs Eagles Prediction & Picks

We cover the essential Rams vs Eagles betting angles, featuring our main match prediction, correct score pick, top player prop plays and a carefully crafted bet builder.

Game Prediction

We expect the Eagles to cover the -3.5 line on the spread. This is a good number and that’s why we’re playing the favorites at -104 for this NFL showdown.

Our NFL handicappers study recent form and take injuries into account when assessing each matchup. Before delivering a verdict, we combine that insight with the latest stats to strengthen our analysis.

Key Rams vs Eagles stats:

• The -3.5 line has been covered by Eagles in 12 consecutive games at home.
• The -3.5 line has been covered by Eagles in 17 of their last 20 games.
• The -3.5 line has been covered by Eagles in 3 consecutive games against Rams.

Eagles -3.5 Probability

The best betting apps imply that our pick has a 51% chance of winning. Based on our in-depth research, we calculate the actual probability to be closer to 60%. This is why we can recommend this wager.

If you are looking for bigger odds, then you are able to move the line. Choose from a range of options and get rewarded if your spread pick exceeds expectations.

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Our Game Prediction

Eagles -3.5 @ -104 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (19:26, 19 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Matthew Stafford Under 228.5 Passing Yards -114

Matthew Stafford (Rams) is available at -114 to end with fewer than 228.5 passing yards. There’s a strong case for choosing him to fall short of the required line in the QB Passing Yards market.

Latest Matthew Stafford Player Prop Odds

Touchdown

Anytime

+2700

First

+10000

Passing Yards

Over 228.5

-112

Under 228.5

-112

Rushing Yards

Over 0.5

+110

Under 0.5

-141

---

DeVonta Smith Under 49.5 Receiving Yards -114

The odds for DeVonta Smith (Eagles) to have less than 49.5 receiving yards stand at -114. There’s a strong case for opting for him to fall short of the required total in the Player Receiving Yards market.

Latest DeVonta Smith Player Prop Odds

Touchdown

Anytime

+240

First

+1200

Receiving Yards

Over 49.5

-112

Under 49.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Rams 23 - 30 Eagles

There are a range of correct score lines to choose from and we’re taking a chance on the Eagles to record a 30-23 victory. There’s a massive return if we get this right.

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Rams vs Eagles Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks’ betting odds have Philadelphia Eagles as -196 favorites for this game, implying that they are 66% likely to win. Los Angeles Rams are regarded as a long shot to win and you can currently back them at +166.

3.5 is the spread and 45.5 is the total points line. The advantage of the Totals is that you only have to choose from one of two options. Those that want to back Under 45.5 can find odds of -115 available.

The top NFL sportsbooks offer a huge selection of game lines and team props when it comes to this popular league. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Rams

+166

Eagles

-196

Point Spread

Rams +3.5

-112

Eagles -3.5

-108

Total Points

Under 45.5

-115

Over 45.5

-105

Jalen Hurts is the market leader to be First TD Scorer at +460. Alternatively, there’s the chance to back him to register a touchdown at any stage at -141.

Touchdown

Jalen Hurts (Eagles)

First TD

+460

Anytime TD

-141

Saquon Barkley (Eagles)

First TD

+470

Anytime TD

-145

Kyren Williams (Rams)

First TD

+600

Anytime TD

-105

Puka Nacua (Rams)

First TD

+900

Anytime TD

+140

AJ Brown (Eagles)

First TD

+1000

Anytime TD

+190

Davante Adams (Rams)

First TD

+1100

Anytime TD

+185

DeVonta Smith (Eagles)

First TD

+1200

Anytime TD

+240

Dallas Goedert (Eagles)

First TD

+1700

Anytime TD

+350

Tyler Higbee (Rams)

First TD

+2200

Anytime TD

+410

Blake Corum (Rams)

First TD

+2700

Anytime TD

+500

Jordan Whittington (Rams)

First TD

+3500

Anytime TD

+750

Tutu Atwell (Rams)

First TD

+3500

Anytime TD

+750

Jahan Dotson (Eagles)

First TD

+4500

Anytime TD

+1100

Will Shipley (Eagles)

First TD

+5000

Anytime TD

+1000

AJ Dillon (Eagles)

First TD

+5000

Anytime TD

+1200

Davis Allen (Rams)

First TD

+5500

Anytime TD

+1100

Tank Bigsby (Eagles)

First TD

+5500

Anytime TD

+1100

Grant Calcaterra (Eagles)

First TD

+6000

Anytime TD

+1100

Jarquez Hunter (Rams)

First TD

+8000

Anytime TD

+1800

Kylen Granson (Eagles)

First TD

+10000

Anytime TD

+2700

John Metchie III (Eagles)

First TD

+10000

Anytime TD

+2200

Terrance Ferguson (Rams)

First TD

+10000

Anytime TD

+2500

Konata Mumpfield (Rams)

First TD

+10000

Anytime TD

+2200

Matthew Stafford (Rams)

First TD

+10000

Anytime TD

+2700

Xavier Smith (Rams)

First TD

+10000

Anytime TD

+3500

Darius Cooper (Eagles)

First TD

+10000

Anytime TD

+3500

Colby Parkinson (Rams)

First TD

+10000

Anytime TD

+2500

Receiving Yards

Puka Nacua (Rams)

Over 83.5

-112

Under 83.5

-112

AJ Brown (Eagles)

Over 67.5

-112

Under 67.5

-112

Davante Adams (Rams)

Over 61.5

-112

Under 61.5

-112

DeVonta Smith (Eagles)

Over 49.5

-112

Under 49.5

-112

Dallas Goedert (Eagles)

Over 35.5

-112

Under 35.5

-112

Tyler Higbee (Rams)

Over 21.5

-112

Under 21.5

-112

Saquon Barkley (Eagles)

Over 13.5

-112

Under 13.5

-112

Jordan Whittington (Rams)

Over 13.5

-112

Under 13.5

-112

Kyren Williams (Rams)

Over 9.5

-112

Under 9.5

-112

Jahan Dotson (Eagles)

Over 7.5

-102

Under 7.5

-123

Rushing Yards

Saquon Barkley (Eagles)

Over 92.5

-112

Under 92.5

-112

Kyren Williams (Rams)

Over 63.5

-112

Under 63.5

-112

Jalen Hurts (Eagles)

Over 38.5

-112

Under 38.5

-112

Blake Corum (Rams)

Over 15.5

-112

Under 15.5

-112

Puka Nacua (Rams)

Over 3.5

-135

Under 3.5

+108

Matthew Stafford (Rams)

Over 0.5

+110

Under 0.5

-141

Passing Yards

Matthew Stafford (Rams)

Over 228.5

-112

Under 228.5

-112

Jalen Hurts (Eagles)

Over 192.5

-112

Under 192.5

-112

There are always opportunities to enjoy NFL micro betting. It’s generally the case that you will find team and player props in-game and bettors can use their insight to wager on outcomes such as the Next Punt, Turnover or Score Play.

Eagles Eye Another Home Win

The Eagles have ten wins and zero loss in the last 10 home games, averaging 29.30 points on offense and surrendering 16.50 on defense.

The Rams have gone 6-4 across their last 10 games away from home, averaging 20.90 points on offense and surrendering 20.90 on defense.

The Eagles defeated the Rams 28-22 in their last meeting at Lincoln Financial Field.

Last 10 Games		W-L	P	PF	PA	O44.5	U44.5
Eagles Home Stats		10-0	45.80	29.30	16.50	4	6
Rams Away Stats		6-4	41.80	20.90	20.90	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O44.5 = Games Over 44.5 Points
• U44.5 = Games Under 44.5 Points

Latest regular season and playoff games stats.

Los Angeles Rams Stats

Philadelphia Eagles Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +3.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +3.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -3.5 Betting Line: Have covered the spread in 8 of the last 10 games
• -3.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 40.50 pts in the previous 10 games
• Game Totals on the Road: An average of 41.80 pts in the previous 10 games on the road
• Over 44.5: Covered in 4 of the previous 10 games
• Over 44.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.00 pts and allowed 17.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 20.90 pts and allowed 20.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 49.30 pts in the previous 10 games
• Game Totals at Home: An average of 46.90 pts in the previous 10 home games
• Over 44.5: Covered in 5 of the previous 10 games
• Over 44.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 31.00 pts and allowed 18.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 30.50 pts and allowed 16.40 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 341.20 Yds. Allowed 315.20 Yds
• Rushing Yards: Gained 114.10 Yds. Allowed 123.70 Yds
• Passing Yards: Gained 227.10 Yds. Allowed 191.50 Yds
• Total Touchdowns: Scored 2.50 TD. Allowed 1.80 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 18.70. Allowed 18.60
• Total Turnovers: Committed 0.60. Committed by opponents 1.00
• Total Penalties: Committed 5.40. Committed by opponents 6.10
• Penalty Yards: Lost 48.40 Yds. Gained 44.50 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 338.00 Yds. Allowed 296.70 Yds
• Rushing Yards: Gained 167.00 Yds. Allowed 100.30 Yds
• Passing Yards: Gained 171.00 Yds. Allowed 196.40 Yds
• Total Touchdowns: Scored 3.50 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 2.00 TD. Allowed 0.50 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 20.40. Allowed 16.60
• Total Turnovers: Committed 0.50. Committed by opponents 2.60
• Total Penalties: Committed 6.00. Committed by opponents 6.20
• Penalty Yards: Lost 49.50 Yds. Gained 58.60 Yds

Last 10 Games on the Road

• Total Yards: Gained 342.90 Yds. Allowed 336.30 Yds
• Rushing Yards: Gained 112.00 Yds. Allowed 143.20 Yds
• Passing Yards: Gained 230.90 Yds. Allowed 193.10 Yds
• Total Touchdowns: Scored 2.20 TD. Allowed 2.20 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 19.50. Allowed 18.90
• Total Turnovers: Committed 0.90. Committed by opponents 1.10
• Total Penalties: Committed 4.80. Committed by opponents 6.90
• Penalty Yards: Lost 42.70 Yds. Gained 53.30 Yds

Last 10 Home Games

• Total Yards: Gained 355.20 Yds. Allowed 287.10 Yds
• Rushing Yards: Gained 177.40 Yds. Allowed 97.90 Yds
• Passing Yards: Gained 177.80 Yds. Allowed 189.20 Yds
• Total Touchdowns: Scored 3.60 TD. Allowed 1.70 TD
• Rushing Touchdowns: Scored 2.00 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 20.90. Allowed 16.40
• Total Turnovers: Committed 0.30. Committed by opponents 2.20
• Total Penalties: Committed 5.50. Committed by opponents 6.10
• Penalty Yards: Lost 44.50 Yds. Gained 51.60 Yds

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