Rams vs Titans Prediction, Picks & Odds | 14 Sep 2025

NFL Betting Preview: Rams vs Titans

The Los Angeles Rams lock horns with the Tennessee Titans in this NFL Week 2 matchup at Nissan Stadium, with kickoff scheduled for 13:00 on Sunday, September 14. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

We’re backing the Rams against the spread when they clash with the Titans. It could be shrewd to wager the favorites to cover the attractive -5.5 line, with odds of -115 on offer.

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Los Angeles Rams won their previous game, beating Houston Texans at home. It was a 14-9 win at SoFi Stadium. The Rams generated 296 yards, including 224 passing and 72 rushing yards. The offense managed 18 first downs and produced 2 touchdowns, combining a passing score with one on the ground.

Tennessee Titans were defeated in their last game. On the road, they suffered a 20-12 reverse against Denver Broncos at Empower Field at Mile High. The Titans moved the ball for 133 yards, made up of 62 through the air and 71 on the ground. They allowed 20 first downs and picked up 7.

Head-to-Head Statistics

The Titans won the most recent matchup between these teams. A 28-16 victory was registered against the Rams at SoFi Stadium.

Quarterbacks

Matthew Stafford

235.5 Passing Yards

Over -112

Under -112

Cam Ward

196.5 Passing Yards

Over -112

Under -112

Rams vs Titans Prediction & Picks

Get the edge with our Rams vs Titans betting tips: a trusted match prediction, likely correct score outcome, key player prop picks and an expert-crafted bet builder.

Game Prediction

The Rams at -5.5 could be the best wager to have on the spread. -115 is available and our pick would mean a solid victory for the favorites in this NFL battle.

The NFL predictions at Sportsgambler.com are always guided by the latest team news, injury updates and overall form. Once we've reviewed that, we dive into the most relevant stats to confidently recommend every pick.

Key Rams vs Titans stats:

• The -5.5 line has been covered by Rams in 4 of their last 5 games on the road.
• The +5.5 line hasn’t been covered by Titans in 5 consecutive games.
• The +5.5 line hasn’t been covered by Titans in 8 of their last 10 games.
• The +5.5 line hasn’t been covered by Titans in 14 of their last 20 games.

Rams -5.5 Probability

According to the latest betting odds, our pick has a 53.5% chance of winning. After careful examination, our analysts calculate this probability to be closer to 60%. It’s why we think it’s worth placing this wager.

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Our Game Prediction

Rams -5.5 @ -115 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (19:26, 12 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Puka Nacua Anytime TD +120

Puka Nacua (Rams) can be backed at +120 to reach the end zone. We think this is the pick of the player props, with generous odds available when it comes to backing him to score a touchdown at any time.

Latest Puka Nacua Player Prop Odds

Touchdown

Anytime

+130

First

+650

Receiving Yards

Over 85.5

-112

Under 85.5

-112

---

Kyren Williams Over 74.5 Rushing Yards -114

The odds for Kyren Williams (Titans) to surpass 74.5 rushing yards stand at -114. We’re confident in taking him to cover the Player Rushing Yards line and bettors can place this bet with confidence.

Latest Kyren Williams Player Prop Odds

Touchdown

Anytime

-154

First

+360

Receiving Yards

Over 10.5

-112

Under 10.5

-112

Rushing Yards

Over 75.5

-112

Under 75.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Rams 24 - 9 Titans

Rather than betting on the Rams to win, there’s the option to try your luck when it comes to the correct score lines. Take a chance on a 24-9 victory in their favor.

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Rams vs Titans Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The Los Angeles Rams odds have been priced up by the sportsbooks and they are -238 betting favorites to land victory in this game which means a 70% chance of winning. If you’re looking for an alternative angle, Tennessee Titans are trading at +198.

The spread is 5.5 and the total points line is currently 41.5. NFL bettors love the chance to get an alternative angle by going for a Total wager. Those that want to back Under 41.5 can find odds of -110 available.

There’s no shortage of betting opportunities when it comes to the National Football League. The top sportsbooks offer a wide variety of game lines and team props for each matchup, so be sure to explore both the pre-game and in-game markets before making your pick.

Moneyline

Rams

-238

Titans

+198

Point Spread

Rams -5.5

-105

Titans +5.5

-115

Total Points

Under 41.5

-110

Over 41.5

-110

There is -154 available that Kyren Williams scores a TD at any stage. He is available at +360 to record the first touchdown which makes him favorite.

Touchdown

Kyren Williams (Rams)

First TD

+360

Anytime TD

-154

Tony Pollard (Titans)

First TD

+440

Anytime TD

-125

Puka Nacua (Rams)

First TD

+650

Anytime TD

+130

Davante Adams (Rams)

First TD

+800

Anytime TD

+165

Calvin Ridley (Titans)

First TD

+1400

Anytime TD

+270

Tyler Higbee (Rams)

First TD

+1600

Anytime TD

+360

Chigoziem Okonkwo (Titans)

First TD

+2000

Anytime TD

+490

Elic Ayomanor (Titans)

First TD

+2000

Anytime TD

+460

Tutu Atwell (Rams)

First TD

+2500

Anytime TD

+600

Cam Ward (Titans)

First TD

+2500

Anytime TD

+650

Tyler Lockett (Titans)

First TD

+3000

Anytime TD

+750

Colby Parkinson (Rams)

First TD

+3300

Anytime TD

+800

Blake Corum (Rams)

First TD

+3300

Anytime TD

+750

Kalel Mullings (Titans)

First TD

+3500

Anytime TD

+700

Julius Chestnut (Titans)

First TD

+4000

Anytime TD

+900

Jordan Whittington (Rams)

First TD

+4000

Anytime TD

+950

Davis Allen (Rams)

First TD

+4000

Anytime TD

+1000

Jarquez Hunter (Rams)

First TD

+6000

Anytime TD

+1700

Gunnar Helm (Titans)

First TD

+7000

Anytime TD

+1600

Chimere Dike (Titans)

First TD

+7500

Anytime TD

+1700

Van Jefferson (Titans)

First TD

+8000

Anytime TD

+1900

Terrance Ferguson (Rams)

First TD

+8000

Anytime TD

+2200

Matthew Stafford (Rams)

First TD

+8000

Anytime TD

+2200

David Martin-Robinson (Titans)

First TD

+10000

Anytime TD

+4000

Konata Mumpfield (Rams)

First TD

+10000

Anytime TD

+3500

Bryce Oliver (Titans)

First TD

+10000

Anytime TD

+3300

Xavier Smith (Rams)

First TD

+10000

Anytime TD

+2500

Jordan Mims (Titans)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Puka Nacua (Rams)

Over 85.5

-112

Under 85.5

-112

Davante Adams (Rams)

Over 60.5

-112

Under 60.5

-112

Calvin Ridley (Titans)

Over 55.5

-112

Under 55.5

-112

Elic Ayomanor (Titans)

Over 33.5

-112

Under 33.5

-112

Chigoziem Okonkwo (Titans)

Over 28.5

-112

Under 28.5

-112

Tutu Atwell (Rams)

Over 20.5

-112

Under 20.5

-112

Tyler Higbee (Rams)

Over 18.5

-112

Under 18.5

-112

Tyler Lockett (Titans)

Over 17.5

-112

Under 17.5

-112

Tony Pollard (Titans)

Over 15.5

-112

Under 15.5

-112

Kyren Williams (Rams)

Over 10.5

-112

Under 10.5

-112

Rushing Yards

Kyren Williams (Rams)

Over 75.5

-112

Under 75.5

-112

Tony Pollard (Titans)

Over 66.5

-112

Under 66.5

-112

Cam Ward (Titans)

Over 12.5

-112

Under 12.5

-112

Passing Yards

Matthew Stafford (Rams)

Over 235.5

-112

Under 235.5

-112

Cam Ward (Titans)

Over 196.5

-112

Under 196.5

-112

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Titans Have Lost Four Straight at Home

The Titans have come out on the wrong side in four straight at Nissan Stadium. They have two wins and eight losses in the last 10 home games, scoring 17.30 points per contest and conceding 22.40.

The Rams have five wins and five losses in the last 10 games on the road, putting up 19.90 points per contest and giving up 21.40.

Last 10 Games		W-L	P	PF	PA	O41.5	U41.5
Titans Home Stats		2-8	39.70	17.30	22.40	3	7
Rams Away Stats		5-5	41.30	19.90	21.40	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O41.5 = Games Over 41.5 Points
• U41.5 = Games Under 41.5 Points

Latest regular season and playoff games stats.

Los Angeles Rams Stats

Tennessee Titans Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 home games

Point Spread

• -5.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -5.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +5.5 Betting Line: Have covered the spread in 2 of the last 10 games
• +5.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 41.00 pts in the previous 10 games
• Game Totals on the Road: An average of 41.30 pts in the previous 10 games on the road
• Over 41.5: Covered in 4 of the previous 10 games
• Over 41.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 21.70 pts and allowed 19.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 19.90 pts and allowed 21.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 45.00 pts in the previous 10 games
• Game Totals at Home: An average of 39.70 pts in the previous 10 home games
• Over 41.5: Covered in 5 of the previous 10 games
• Over 41.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 18.30 pts and allowed 26.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 17.30 pts and allowed 22.40 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 326.30 Yds. Allowed 338.10 Yds
• Rushing Yards: Gained 108.40 Yds. Allowed 144.20 Yds
• Passing Yards: Gained 217.90 Yds. Allowed 193.90 Yds
• Total Touchdowns: Scored 2.40 TD. Allowed 2.10 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 18.80. Allowed 19.20
• Total Turnovers: Committed 0.60. Committed by opponents 0.90
• Total Penalties: Committed 5.40. Committed by opponents 5.50
• Penalty Yards: Lost 49.30 Yds. Gained 43.50 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 293.40 Yds. Allowed 345.40 Yds
• Rushing Yards: Gained 92.10 Yds. Allowed 152.00 Yds
• Passing Yards: Gained 201.30 Yds. Allowed 193.40 Yds
• Total Touchdowns: Scored 1.80 TD. Allowed 3.30 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 1.40 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 16.50. Allowed 20.30
• Total Turnovers: Committed 1.90. Committed by opponents 1.60
• Total Penalties: Committed 8.50. Committed by opponents 7.10
• Penalty Yards: Lost 69.00 Yds. Gained 56.80 Yds

Last 10 Games on the Road

• Total Yards: Gained 341.50 Yds. Allowed 344.50 Yds
• Rushing Yards: Gained 103.90 Yds. Allowed 140.20 Yds
• Passing Yards: Gained 237.60 Yds. Allowed 204.30 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 19.50. Allowed 19.40
• Total Turnovers: Committed 0.80. Committed by opponents 1.00
• Total Penalties: Committed 4.80. Committed by opponents 6.40
• Penalty Yards: Lost 43.40 Yds. Gained 50.50 Yds

Last 10 Home Games

• Total Yards: Gained 304.60 Yds. Allowed 319.40 Yds
• Rushing Yards: Gained 114.00 Yds. Allowed 107.90 Yds
• Passing Yards: Gained 190.60 Yds. Allowed 211.50 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 18.70. Allowed 19.50
• Total Turnovers: Committed 1.60. Committed by opponents 1.40
• Total Penalties: Committed 7.90. Committed by opponents 7.00
• Penalty Yards: Lost 66.00 Yds. Gained 56.50 Yds

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