Patriots vs 49ers Prediction, Picks & Odds | 29 Sep 2024

Patriots Betting Line Looks Too Generous

The Patriots can give a good account of themselves against the Niners. They can prevent a big loss and there is -110 available that the underdogs cover the +10.5 spread.

Niners Came Out on Top in Previous H2H

New England Patriots have suffered a defeat in back-to-back games including a recent 24-3 loss. This occurred on the road at MetLife Stadium against New York Jets. The Patriots 139 yards total gain included 61 passing and 78 rushing yards. They picked up 11 first downs and allowed 27.

San Francisco 49ers have suffered defeat in their last two games. Most recently, a 27-24 scoreline occurred on the road at SoFi Stadium against Los Angeles Rams. The 49ers managed a 425 yard gain, composed of 137 rushing and 288 passing yards. They picked up 25 first downs and scored 3 touchdowns.

Head-to-Head Statistics

These two teams last met at Gillette Stadium, with the Niners claiming the win. Beating the Patriots by a 33-6 scoreline.

Patriots vs 49ers Prediction & Picks

Our pick is that the Patriots might not be beaten heavily in this NFL matchup. The underdogs have been afforded a generous +10.5 and we recommend backing them at odds of -110.

The team news that filters through can have a knock-on effect as far as the NFL betting lines and odds are concerned. We use this information along with the form guide, while some key stats are also taken into consideration.

Key Patriots vs 49ers stats:

• The +10.5 line has been covered by Patriots in 4 of their last 5 games on the road.
• The +10.5 line has been covered by Patriots in 8 of their last 10 games.
• The -10.5 line hasn’t been covered by 49ers in 4 of their last 5 games at home.
• The -10.5 line hasn’t been covered by 49ers in 7 of their last 10 games.
• The -10.5 line hasn’t been covered by 49ers in 2 consecutive games.

Patriots +10.5 Probability

The sportsbooks imply that our pick has a 52.4% prospect of winning. Based on our cappers in-depth research, we calculate the actual probability to be closer to 60%. This wager can therefore be backed with confidence.

Bettors can choose between buying or selling points depending on their attitude to risk. When you move the line in either direction, the odds change accordingly.

Best Bet

Patriots +10.5 @ -110 Bet Now

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Correct Score Prediction

Patriots 21 - 27 49ers

The 49ers can be wagered in lots of different ways and this includes the correct score lines. There’s the chance to back them to win 27-21 for a big potential return.

Patriots vs 49ers Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Niners Heavy Favorites to Win

The latest Moneyline betting odds give San Francisco 49ers a 85% chance of winning this game which means they’re overwhelming -588 favorites with the sportsbooks. New England Patriots are trading at bigger odds than their opponents and they can be backed at +430.

The current spread is 11 and total points is 42. A bet on the Totals allows fans to use the latest NFL data to good effect. If you’re going for Under 42, this outcome can be backed at -102.

There are hundreds of team props and game lines when it comes to wagering on the National Football League and we recommend visiting the top betting sites to find the bet that matches your view on the game.

Moneyline

Patriots

+430

49ers

-588

Point Spread

Patriots +11

-110

49ers -11

-104

Total Points

Under 42

-102

Over 42

-104

Player Props & Micro Betting

If you have a view on Player Interceptions, Longest Pass Completion or Passing Attempts, then the player and quarterback prop betting could be up your street. It’s a great way of wagering on a player to perform well.

Micro betting is an exciting way to wager on the NFL. There are a huge range of live lines and it’s a simple case of predicting what is going to happen next. Field Goal Outcome, Next Play Result and Next Drive Result are often among the options.

Last 5 & H2H

Latest regular season and playoff games stats.

New England Patriots Stats

San Francisco 49ers Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +10.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +10.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -10.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -10.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 31.90 pts in the previous 10 games
• Game Totals on the Road: An average of 35.80 pts in the previous 10 games on the road
• Over 40.5: Covered in 4 of the previous 10 games
• Over 40.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 13.40 pts and allowed 18.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 14.60 pts and allowed 21.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 50.30 pts in the previous 10 games
• Game Totals at Home: An average of 49.00 pts in the previous 10 home games
• Over 40.5: Covered in 8 of the previous 10 games
• Over 40.5 at Home: Covered in the previous 10 home games
• Team Totals: Have scored an average of 26.40 pts and allowed 23.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 27.80 pts and allowed 21.20 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 249.00 Yds. Allowed 284.40 Yds
• Rushing Yards: Gained 111.10 Yds. Allowed 85.60 Yds
• Passing Yards: Gained 137.90 Yds. Allowed 198.80 Yds
• Total Touchdowns: Scored 1.50 TD. Allowed 1.90 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 0.70 TD. Allowed 1.00 TD
• Total 1st Downs: Picked up 13.60. Allowed 16.90
• Total Turnovers: Committed 1.40. Committed by opponents 1.00
• Total Penalties: Committed 3.90. Committed by opponents 3.40
• Penalty Yards: Lost 36.30 Yds. Gained 30.50 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 391.90 Yds. Allowed 345.40 Yds
• Rushing Yards: Gained 136.90 Yds. Allowed 126.70 Yds
• Passing Yards: Gained 255.00 Yds. Allowed 218.70 Yds
• Total Touchdowns: Scored 3.00 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.60 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 23.10. Allowed 19.80
• Total Turnovers: Committed 1.20. Committed by opponents 1.40
• Total Penalties: Committed 4.90. Committed by opponents 4.40
• Penalty Yards: Lost 43.30 Yds. Gained 35.60 Yds

Last 10 Games on the Road

• Total Yards: Gained 268.60 Yds. Allowed 295.10 Yds
• Rushing Yards: Gained 100.80 Yds. Allowed 87.70 Yds
• Passing Yards: Gained 167.80 Yds. Allowed 207.40 Yds
• Total Touchdowns: Scored 1.60 TD. Allowed 2.30 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 0.80 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 14.50. Allowed 18.30
• Total Turnovers: Committed 1.50. Committed by opponents 1.00
• Total Penalties: Committed 5.30. Committed by opponents 3.80
• Penalty Yards: Lost 44.40 Yds. Gained 32.90 Yds

Last 10 Home Games

• Total Yards: Gained 412.20 Yds. Allowed 320.90 Yds
• Rushing Yards: Gained 138.70 Yds. Allowed 102.90 Yds
• Passing Yards: Gained 273.50 Yds. Allowed 218.00 Yds
• Total Touchdowns: Scored 3.40 TD. Allowed 2.60 TD
• Rushing Touchdowns: Scored 1.90 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 22.70. Allowed 20.30
• Total Turnovers: Committed 1.30. Committed by opponents 1.50
• Total Penalties: Committed 5.50. Committed by opponents 3.80
• Penalty Yards: Lost 53.90 Yds. Gained 29.30 Yds

Team News

NFL Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Division Conference League

AFC East	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bills	2	0	0	1.000	71	50	21	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Patriots	1	1	0	0.500	46	47	-1	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1W
Jets	0	2	0	0.000	42	64	-22	0-2-0	0-0-0	0-1-0	0-2-0	0-2-0	2L
Dolphins	0	2	0	0.000	35	66	-31	0-1-0	0-1-0	0-1-0	0-2-0	0-2-0	2L

AFC North	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Bengals	2	0	0	1.000	48	43	5	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Steelers	1	1	0	0.500	51	63	-12	0-1-0	1-0-0	0-0-0	1-0-0	1-1-0	1L
Browns	0	2	0	0.000	33	58	-25	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L

AFC South	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Colts	2	0	0	1.000	62	36	26	2-0-0	0-0-0	0-0-0	2-0-0	2-0-0	2W
Jaguars	1	1	0	0.500	53	41	12	1-0-0	0-1-0	0-0-0	0-1-0	1-1-0	1L
Texans	0	2	0	0.000	28	34	-6	0-1-0	0-1-0	0-0-0	0-0-0	0-2-0	2L
Titans	0	2	0	0.000	31	53	-22	0-1-0	0-1-0	0-0-0	0-1-0	0-2-0	2L

AFC West	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Chargers	2	0	0	1.000	47	30	17	1-0-0	1-0-0	2-0-0	2-0-0	2-0-0	2W
Raiders	1	1	0	0.500	29	33	-4	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1L
Broncos	1	1	0	0.500	48	41	7	1-0-0	0-1-0	0-0-0	1-1-0	1-1-0	1L
Chiefs	0	2	0	0.000	38	47	-9	0-1-0	0-1-0	0-1-0	0-1-0	0-2-0	2L

NFC East	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Eagles	2	0	0	1.000	44	37	7	1-0-0	1-0-0	1-0-0	1-0-0	2-0-0	2W
Commanders	1	1	0	0.500	39	33	6	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1L
Cowboys	1	1	0	0.500	60	61	-1	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Giants	0	2	0	0.000	43	61	-18	0-0-0	0-2-0	0-2-0	0-2-0	0-2-0	2L

NFC North	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Packers	2	0	0	1.000	54	31	23	2-0-0	0-0-0	1-0-0	2-0-0	2-0-0	2W
Vikings	1	1	0	0.500	33	46	-13	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1L
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Bears	0	2	0	0.000	45	79	-34	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L

NFC South	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Buccaneers	2	0	0	1.000	43	39	4	0-0-0	2-0-0	1-0-0	1-0-0	2-0-0	2W
Falcons	1	1	0	0.500	42	29	13	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1W
Saints	0	2	0	0.000	34	46	-12	0-2-0	0-0-0	0-0-0	0-2-0	0-2-0	2L
Panthers	0	2	0	0.000	32	53	-21	0-0-0	0-2-0	0-0-0	0-1-0	0-2-0	2L

NFC West	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
49ers	2	0	0	1.000	43	34	9	0-0-0	2-0-0	1-0-0	2-0-0	2-0-0	2W
Cardinals	2	0	0	1.000	47	35	12	1-0-0	1-0-0	0-0-0	2-0-0	2-0-0	2W
Rams	2	0	0	1.000	47	28	19	1-0-0	1-0-0	0-0-0	0-0-0	2-0-0	2W
Seahawks	1	1	0	0.500	44	34	10	0-1-0	1-0-0	0-1-0	0-1-0	1-1-0	1W

AFC Conference	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Colts	2	0	0	1.000	62	36	26	2-0-0	0-0-0	0-0-0	2-0-0	2-0-0	2W
Bills	2	0	0	1.000	71	50	21	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Chargers	2	0	0	1.000	47	30	17	1-0-0	1-0-0	2-0-0	2-0-0	2-0-0	2W
Bengals	2	0	0	1.000	48	43	5	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Raiders	1	1	0	0.500	29	33	-4	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1L
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Patriots	1	1	0	0.500	46	47	-1	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1W
Steelers	1	1	0	0.500	51	63	-12	0-1-0	1-0-0	0-0-0	1-0-0	1-1-0	1L
Broncos	1	1	0	0.500	48	41	7	1-0-0	0-1-0	0-0-0	1-1-0	1-1-0	1L
Jaguars	1	1	0	0.500	53	41	12	1-0-0	0-1-0	0-0-0	0-1-0	1-1-0	1L
Titans	0	2	0	0.000	31	53	-22	0-1-0	0-1-0	0-0-0	0-1-0	0-2-0	2L
Dolphins	0	2	0	0.000	35	66	-31	0-1-0	0-1-0	0-1-0	0-2-0	0-2-0	2L
Chiefs	0	2	0	0.000	38	47	-9	0-1-0	0-1-0	0-1-0	0-1-0	0-2-0	2L
Jets	0	2	0	0.000	42	64	-22	0-2-0	0-0-0	0-1-0	0-2-0	0-2-0	2L
Browns	0	2	0	0.000	33	58	-25	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Texans	0	2	0	0.000	28	34	-6	0-1-0	0-1-0	0-0-0	0-0-0	0-2-0	2L

NFC Conference	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Packers	2	0	0	1.000	54	31	23	2-0-0	0-0-0	1-0-0	2-0-0	2-0-0	2W
Eagles	2	0	0	1.000	44	37	7	1-0-0	1-0-0	1-0-0	1-0-0	2-0-0	2W
Buccaneers	2	0	0	1.000	43	39	4	0-0-0	2-0-0	1-0-0	1-0-0	2-0-0	2W
49ers	2	0	0	1.000	43	34	9	0-0-0	2-0-0	1-0-0	2-0-0	2-0-0	2W
Cardinals	2	0	0	1.000	47	35	12	1-0-0	1-0-0	0-0-0	2-0-0	2-0-0	2W
Rams	2	0	0	1.000	47	28	19	1-0-0	1-0-0	0-0-0	0-0-0	2-0-0	2W
Falcons	1	1	0	0.500	42	29	13	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1W
Commanders	1	1	0	0.500	39	33	6	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1L
Vikings	1	1	0	0.500	33	46	-13	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1L
Cowboys	1	1	0	0.500	60	61	-1	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Seahawks	1	1	0	0.500	44	34	10	0-1-0	1-0-0	0-1-0	0-1-0	1-1-0	1W
Panthers	0	2	0	0.000	32	53	-21	0-0-0	0-2-0	0-0-0	0-1-0	0-2-0	2L
Bears	0	2	0	0.000	45	79	-34	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Saints	0	2	0	0.000	34	46	-12	0-2-0	0-0-0	0-0-0	0-2-0	0-2-0	2L
Giants	0	2	0	0.000	43	61	-18	0-0-0	0-2-0	0-2-0	0-2-0	0-2-0	2L

NFL Team	W	L	T	PCT	PF	PA	N. Pts	Home	Road	Div	Conf	Last 5	Strk
Cardinals	2	0	0	1.000	47	35	12	1-0-0	1-0-0	0-0-0	2-0-0	2-0-0	2W
Bills	2	0	0	1.000	71	50	21	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Bengals	2	0	0	1.000	48	43	5	1-0-0	1-0-0	1-0-0	2-0-0	2-0-0	2W
Packers	2	0	0	1.000	54	31	23	2-0-0	0-0-0	1-0-0	2-0-0	2-0-0	2W
Colts	2	0	0	1.000	62	36	26	2-0-0	0-0-0	0-0-0	2-0-0	2-0-0	2W
Chargers	2	0	0	1.000	47	30	17	1-0-0	1-0-0	2-0-0	2-0-0	2-0-0	2W
Rams	2	0	0	1.000	47	28	19	1-0-0	1-0-0	0-0-0	0-0-0	2-0-0	2W
Eagles	2	0	0	1.000	44	37	7	1-0-0	1-0-0	1-0-0	1-0-0	2-0-0	2W
49ers	2	0	0	1.000	43	34	9	0-0-0	2-0-0	1-0-0	2-0-0	2-0-0	2W
Buccaneers	2	0	0	1.000	43	39	4	0-0-0	2-0-0	1-0-0	1-0-0	2-0-0	2W
Falcons	1	1	0	0.500	42	29	13	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1W
Ravens	1	1	0	0.500	81	58	23	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1W
Cowboys	1	1	0	0.500	60	61	-1	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Broncos	1	1	0	0.500	48	41	7	1-0-0	0-1-0	0-0-0	1-1-0	1-1-0	1L
Lions	1	1	0	0.500	65	48	17	1-0-0	0-1-0	1-1-0	1-1-0	1-1-0	1W
Jaguars	1	1	0	0.500	53	41	12	1-0-0	0-1-0	0-0-0	0-1-0	1-1-0	1L
Raiders	1	1	0	0.500	29	33	-4	0-1-0	1-0-0	0-1-0	1-1-0	1-1-0	1L
Vikings	1	1	0	0.500	33	46	-13	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1L
Patriots	1	1	0	0.500	46	47	-1	0-1-0	1-0-0	1-0-0	1-1-0	1-1-0	1W
Steelers	1	1	0	0.500	51	63	-12	0-1-0	1-0-0	0-0-0	1-0-0	1-1-0	1L
Seahawks	1	1	0	0.500	44	34	10	0-1-0	1-0-0	0-1-0	0-1-0	1-1-0	1W
Commanders	1	1	0	0.500	39	33	6	1-0-0	0-1-0	1-0-0	1-1-0	1-1-0	1L
Panthers	0	2	0	0.000	32	53	-21	0-0-0	0-2-0	0-0-0	0-1-0	0-2-0	2L
Bears	0	2	0	0.000	45	79	-34	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Browns	0	2	0	0.000	33	58	-25	0-1-0	0-1-0	0-2-0	0-2-0	0-2-0	2L
Texans	0	2	0	0.000	28	34	-6	0-1-0	0-1-0	0-0-0	0-0-0	0-2-0	2L
Chiefs	0	2	0	0.000	38	47	-9	0-1-0	0-1-0	0-1-0	0-1-0	0-2-0	2L
Dolphins	0	2	0	0.000	35	66	-31	0-1-0	0-1-0	0-1-0	0-2-0	0-2-0	2L
Saints	0	2	0	0.000	34	46	-12	0-2-0	0-0-0	0-0-0	0-2-0	0-2-0	2L
Giants	0	2	0	0.000	43	61	-18	0-0-0	0-2-0	0-2-0	0-2-0	0-2-0	2L
Jets	0	2	0	0.000	42	64	-22	0-2-0	0-0-0	0-1-0	0-2-0	0-2-0	2L
Titans	0	2	0	0.000	31	53	-22	0-1-0	0-1-0	0-0-0	0-1-0	0-2-0	2L