Giants vs Commanders Prediction, Picks & Odds | 07 Sep 2025

NFL Betting Preview: Giants vs Commanders

The New York Giants battle the Washington Commanders in this NFL Week 1 matchup at Northwest Stadium, with kickoff scheduled for 13:00 on Sunday, September 7. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

There could be plenty of points when the Commanders clash with the Giants, with our prediction being Over 45.5 points in total. Odds of -105 look worth taking for this outcome.

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New York Giants were beaten in their previous game and this was on the road at Lincoln Financial Field. Philadelphia Eagles claimed a 20-13 win. The Giants finished with 238 yards, including 138 passing and 100 rushing yards. Their output included 10 first downs and one touchdown through the air.

Washington Commanders lost their last game, suffering a 55-23 road defeat to the Philadelphia Eagles in the NFC Championship Game at Lincoln Financial Field. The Commanders generated 350 total yards, including 251 passing and 99 rushing yards. They converted 22 first downs and scored two touchdowns, split evenly between run and pass.

Head-to-Head Statistics

The Commanders have beaten the Giants in the last two meetings. They won 21-18 at Northwest Stadium and triumphed 27-22 at MetLife Stadium. In the past 10 clashes between these teams, there has been one draw. The Giants have won five games and the Commanders four.

Quarterbacks

Russell Wilson

217.5 Passing Yards

Over -114

Under -114

Jayden Daniels

222.5 Passing Yards

Over -114

Under -114

Giants vs Commanders Prediction & Picks

Head into Giants vs Commanders with expert betting insights, including our main match prediction, expected scoreline, key player prop picks and a thoughtfully built bet builder.

Game Prediction

We’re expecting Over 45.5 points to be scored by the two teams combined. There’s an attractive -105 for our pick and we’re anticipating that the scoreboard will tick over in this NFL matchup.

The NFL predictions at Sportsgambler.com are always guided by the latest team news, injury updates and overall form. Once we've reviewed that, we dive into the most relevant stats to confidently recommend every pick.

Key Giants vs Commanders stats:

• The 45.5 line has been covered in the last 5 Commanders games at home.
• The 45.5 line has been covered in 8 of the last 10 Commanders games at home.
• The 45.5 line has been covered in 14 of the last 20 Commanders games.

Over 45.5 Probability

When you look at the latest betting odds, our pick has a 51.3% chance of winning. After careful examination, our cappers have this probability close to 60%. It's therefore regarded as a value wager.

Looking for a bigger return on your Total bet? Consider the Result & Total lines where you combine the winning franchise and Over a certain number of points.

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Our Game Prediction

Over 45.5 Points @ -105 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (19:26, 05 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Austin Ekeler Anytime TD +145

You can place a bet on Austin Ekeler (Commanders) to score a TD at +145. Attractive odds are available for this Anytime Touchdown Scorer wager, and we believe it's a value proposition for him to take it to the house.

Latest Austin Ekeler Player Prop Odds

Touchdown

Anytime

+145

First

+750

Receiving Yards

Over 21.5

-114

Under 21.5

-114

Rushing Yards

Over 24.5

-114

Under 24.5

-114

---

Russell Wilson Over 217.5 Passing Yards -114

You can back Russell Wilson (Giants) at -114 to go over 217.5 passing yards. The line for him on the Overs looks attractive and bettors can get plenty of juice from this QB Passing Yards wager.

Latest Russell Wilson Player Prop Odds

Touchdown

Anytime

+800

First

+3500

Passing Yards

Over 217.5

-114

Under 217.5

-114

Rushing Yards

Over 9.5

-114

Under 9.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Giants 20 - 31 Commanders

The Commanders might be able to claim a victory and we’re siding with a 31-20 scoreline in their favor. A small stake can provide a big return and there are monster odds available.

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Giants vs Commanders Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks’ betting odds have Washington Commanders as -294 favorites for this game, implying that they are 75% likely to win. The market suggests that New York Giants are least likely to win at +235.

The spread currently stands at 6.5 and the total points line is 45.5. NFL bettors love the chance to get an alternative angle by going for a Total wager. If you want to back Over 45.5, it’s -108.

Whether you're placing bets before kickoff or during the game, the best NFL sportsbooks delivers a massive range of game lines and team props. The betting sites give you endless ways to get involved with plenty of exciting alternatives.

Moneyline

Giants

+235

Commanders

-294

Point Spread

Giants +6.5

-118

Commanders -6.5

-104

Total Points

Under 45.5

-112

Over 45.5

-108

The First Touchdown Scorer favorite is Terry McLaurin at +750. Similar odds can be found if you’re interested in this player to register the final TD.

Touchdown

Terry McLaurin (Commanders)

First TD

+750

Anytime TD

+130

Austin Ekeler (Commanders)

First TD

+750

Anytime TD

+145

Tyrone Tracy Jr. (Giants)

First TD

+800

Anytime TD

+140

Jayden Daniels (Commanders)

First TD

+850

Anytime TD

+170

Jacory Croskey-Merritt (Commanders)

First TD

+1000

Anytime TD

+200

Malik Nabers (Giants)

First TD

+1000

Anytime TD

+160

Zach Ertz (Commanders)

First TD

+1000

Anytime TD

+210

Deebo Samuel Sr. (Commanders)

First TD

+1100

Anytime TD

+200

Chris Rodriguez Jr. (Commanders)

First TD

+1600

Anytime TD

+330

Theo Johnson (Giants)

First TD

+2200

Anytime TD

+430

Wan'Dale Robinson (Giants)

First TD

+2200

Anytime TD

+410

Devin Singletary (Giants)

First TD

+2500

Anytime TD

+470

Cam Skattebo (Giants)

First TD

+2500

Anytime TD

+440

Darius Slayton (Giants)

First TD

+2500

Anytime TD

+440

Noah Brown (Commanders)

First TD

+2700

Anytime TD

+650

Jeremy McNichols (Commanders)

First TD

+2700

Anytime TD

+500

Russell Wilson (Giants)

First TD

+3500

Anytime TD

+800

Washington Commanders Defense (Commanders)

First TD

+3500

Anytime TD

+650

Jaylin Lane (Commanders)

First TD

+4000

Anytime TD

+1000

New York Giants Defense (Giants)

First TD

+4000

Anytime TD

+950

Jalin Hyatt (Giants)

First TD

+7000

Anytime TD

+1300

Ben Sinnott (Commanders)

First TD

+7000

Anytime TD

+1800

Beaux Collins (Giants)

First TD

+7000

Anytime TD

+1300

John Bates (Commanders)

First TD

+7500

Anytime TD

+1800

Daniel Bellinger (Giants)

First TD

+8000

Anytime TD

+1600

Luke McCaffrey (Commanders)

First TD

+8000

Anytime TD

+2200

Ihmir Smith-Marsette (Giants)

First TD

+10000

Anytime TD

+2700

Chris Moore (Commanders)

First TD

+10000

Anytime TD

+2200

Gunner Olszewski (Giants)

First TD

+10000

Anytime TD

+2700

Chris Manhertz (Giants)

First TD

+10000

Anytime TD

+3300

Thomas Fidone (Giants)

First TD

+10000

Anytime TD

+3300

Receiving Yards

Malik Nabers (Giants)

Over 75.5

-114

Under 75.5

-114

Terry McLaurin (Commanders)

Over 54.5

-114

Under 54.5

-114

Deebo Samuel Sr. (Commanders)

Over 46.5

-114

Under 46.5

-114

Wan'Dale Robinson (Giants)

Over 34.5

-114

Under 34.5

-114

Zach Ertz (Commanders)

Over 32.5

-114

Under 32.5

-114

Darius Slayton (Giants)

Over 26.5

-114

Under 26.5

-114

Theo Johnson (Giants)

Over 23.5

-114

Under 23.5

-114

Austin Ekeler (Commanders)

Over 21.5

-114

Under 21.5

-114

Tyrone Tracy Jr. (Giants)

Over 11.5

-114

Under 11.5

-114

Rushing Yards

Tyrone Tracy Jr. (Giants)

Over 56.5

-114

Under 56.5

-114

Jayden Daniels (Commanders)

Over 44.5

-114

Under 44.5

-114

Jacory Croskey-Merritt (Commanders)

Over 39.5

-114

Under 39.5

-114

Austin Ekeler (Commanders)

Over 24.5

-114

Under 24.5

-114

Chris Rodriguez Jr. (Commanders)

Over 22.5

-114

Under 22.5

-114

Cam Skattebo (Giants)

Over 16.5

-114

Under 16.5

-114

Russell Wilson (Giants)

Over 9.5

-114

Under 9.5

-114

Passing Yards

Jayden Daniels (Commanders)

Over 222.5

-114

Under 222.5

-114

Russell Wilson (Giants)

Over 217.5

-114

Under 217.5

-114

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Can Commanders Keep Their Home Streak Alive?

The Commanders have reeled off three in a row at Northwest Stadium. They are 7-3 in their last 10 home games, putting up 28.40 points per contest and giving up 22.90.

The Giants have fallen in five consecutive away contests. They have two wins and eight losses in the last 10 road games, posting 17.40 points per matchup while yielding 24.00.

The last time these teams met at Northwest Stadium, the Commanders came out on top 21-18 against the Giants. In 6 meetings at Northwest Stadium, the Giants have four wins to their name, with the Commanders having two.

Last 10 Games		W-L	P	PF	PA	O45.5	U45.5
Commanders Home Stats		7-3	51.30	28.40	22.90	8	2
Giants Away Stats		2-8	41.40	17.40	24.00	3	7

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O45.5 = Games Over 45.5 Points
• U45.5 = Games Under 45.5 Points

Latest regular season and playoff games stats.

New York Giants Stats

Washington Commanders Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 44.00 pts in the previous 10 games
• Game Totals on the Road: An average of 41.40 pts in the previous 10 games on the road
• Over 45.5: Covered in 4 of the previous 10 games
• Over 45.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 17.40 pts and allowed 26.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 17.40 pts and allowed 24.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 56.60 pts in the previous 10 games
• Game Totals at Home: An average of 51.30 pts in the previous 10 home games
• Over 45.5: Covered in 6 of the previous 10 games
• Over 45.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 28.60 pts and allowed 28.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 28.40 pts and allowed 22.90 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 297.60 Yds. Allowed 367.20 Yds
• Rushing Yards: Gained 107.20 Yds. Allowed 134.80 Yds
• Passing Yards: Gained 190.40 Yds. Allowed 232.40 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 3.10 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 0.90 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 17.50. Allowed 21.20
• Total Turnovers: Committed 1.50. Committed by opponents 0.90
• Total Penalties: Committed 7.60. Committed by opponents 5.50
• Penalty Yards: Lost 64.60 Yds. Gained 46.90 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 369.50 Yds. Allowed 357.30 Yds
• Rushing Yards: Gained 144.80 Yds. Allowed 144.10 Yds
• Passing Yards: Gained 224.70 Yds. Allowed 213.20 Yds
• Total Touchdowns: Scored 3.50 TD. Allowed 3.20 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 1.80 TD
• Passing Touchdowns: Scored 2.30 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 23.00. Allowed 21.40
• Total Turnovers: Committed 1.60. Committed by opponents 1.30
• Total Penalties: Committed 7.00. Committed by opponents 6.60
• Penalty Yards: Lost 61.90 Yds. Gained 50.70 Yds

Last 10 Games on the Road

• Total Yards: Gained 300.40 Yds. Allowed 341.70 Yds
• Rushing Yards: Gained 116.70 Yds. Allowed 129.80 Yds
• Passing Yards: Gained 183.70 Yds. Allowed 211.90 Yds
• Total Touchdowns: Scored 1.90 TD. Allowed 2.30 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 0.90 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 17.20. Allowed 20.20
• Total Turnovers: Committed 1.60. Committed by opponents 0.80
• Total Penalties: Committed 6.70. Committed by opponents 6.10
• Penalty Yards: Lost 45.60 Yds. Gained 48.50 Yds

Last 10 Home Games

• Total Yards: Gained 383.80 Yds. Allowed 300.70 Yds
• Rushing Yards: Gained 166.40 Yds. Allowed 125.80 Yds
• Passing Yards: Gained 217.40 Yds. Allowed 174.90 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 1.20 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.80 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 22.10. Allowed 18.10
• Total Turnovers: Committed 1.60. Committed by opponents 1.40
• Total Penalties: Committed 7.10. Committed by opponents 6.50
• Penalty Yards: Lost 60.90 Yds. Gained 48.90 Yds

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