Eagles vs Chiefs Prediction, Picks & Odds | 14 Sep 2025

NFL Betting Preview: Eagles vs Chiefs

It's a rematch of Super Bowl LIX when the Philadelphia Eagles lock horns with the Kansas City Chiefs in this NFL Week 2 matchup at GEHA Field at Arrowhead Stadium, with kickoff scheduled for 16:25 on Sunday, September 14. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

The Eagles look great value on the Moneyline and our prediction is that the Birds will claim a victory over the Chiefs. We’re happy to take the -116 that they win.

If you're picking Eagles, don’t place that bet just yet — grab the latest BetMGM promo code and check out our in-depth review for key insights first.

Philadelphia Eagles won their previous game, beating Dallas Cowboys at home. It was a 24-20 win at Lincoln Financial Field. The Eagles recorded 302 yards, with 144 through the air and 158 on the ground. They generated 20 first downs to go with 3 trips to the end zone.

Kansas City Chiefs suffered a defeat in their last game. A 27-21 scoreline occurred on the road at SoFi Stadium against Los Angeles Chargers. The Chiefs moved the ball for 347 yards, including 249 passing and 98 rushing yards. The offense managed 18 first downs and found the end zone on two occasions.

Head-to-Head Statistics

The Eagles have won the last two matchups against the Chiefs. They triumphed 21-17 at GEHA Field at Arrowhead Stadium and then 40-22 in the Super Bowl LIX at Caesars Superdome. Both teams have two wins on the board when we look at the 4-game H2H record.

Quarterbacks

Jalen Hurts

212.5 Passing Yards

Over -112

Under -112

Patrick Mahomes

236.5 Passing Yards

Over -112

Under -112

Eagles vs Chiefs Prediction & Picks

We cover the essential Eagles vs Chiefs betting angles, featuring our main match prediction, correct score pick, top player prop plays and a carefully crafted bet builder.

Game Prediction

This NFL matchup could go the way of the Eagles and they are our pick on the Moneyline. You can land -116 that they beat their opponents and claim a victory.

The NFL handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.

Key Eagles vs Chiefs stats:

• Eagles have won 7 consecutive games.
• Eagles have won 9 of their last 10 games.
• Eagles have won 18 of their last 20 games.
• Chiefs have lost 3 of their last 5 games.
• Chiefs have lost their last 2 games.
• Chiefs have lost their last 2 games against Eagles.

Eagles Moneyline Probability

When you look at the latest betting odds, our pick has a 53.8% chance of winning. However, our research has found that the actual probability is closer to 60%. It’s why we think it’s worth placing this wager.

The Eagles are available at a range of odds on the spread. If you are looking for more juice, then check out the latest lines and choose from the available options.

Claim bonuses and free bets before placing a wager. Our in-depth guide shows you the best current betting offers.

Our Game Prediction

Eagles Moneyline @ -116 Bet Now

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Player Prop Picks

Top Pick: Patrick Mahomes Under 235.5 Passing Yards -114

Patrick Mahomes (Chiefs) is priced at -114 to finish with fewer than 235.5 passing yards. Considering all factors, we’re confident he’ll fall short of the QB Passing Yards line.

Latest Patrick Mahomes Player Prop Odds

Touchdown

Anytime

+400

First

+2000

Passing Yards

Over 236.5

-112

Under 236.5

-112

Rushing Yards

Over 23.5

-112

Under 23.5

-112

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AJ Brown Under 73.5 Receiving Yards -114

AJ Brown (Eagles) can be backed at -114 to end with fewer than 73.5 receiving yards. There’s no reason to doubt our instinct, so we’ll bet on him falling short of the Player Receiving Yards line.

Latest AJ Brown Player Prop Odds

Touchdown

Anytime

+190

First

+1000

Receiving Yards

Over 76.5

-112

Under 76.5

-112

Correct Score Prediction

Eagles 28 - 24 Chiefs

There might not be too much between these teams, with our correct score prediction being a 28-24 win for the Eagles. There are enormous odds available when it comes to this pick.

Eagles vs Chiefs Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

There are betting odds of +106 about Kansas City Chiefs winning, with Philadelphia Eagles currently available at -123. The sportsbook traders give the road team a 55% probability of success.

1.5 is the spread and 46.5 is the total points line. A Total wager relates to the number of points that will be scored overall. If you want to bet Under 46.5, there are odds of -105.

If you’re wagering on the National Football League, we recommend heading to the best sportsbooks and scanning through the hundreds of game lines and team props. There’s a chance to bet pre-game and in-game.

Moneyline

Eagles

-123

Chiefs

+106

Point Spread

Eagles -1.5

-110

Chiefs +1.5

-110

Total Points

Under 46.5

-105

Over 46.5

-115

Saquon Barkley can be backed to score a touchdown at anytime at -154. He is the favorite to score the first TD at odds of +480.

Touchdown

Saquon Barkley (Eagles)

First TD

+480

Anytime TD

-154

Jalen Hurts (Eagles)

First TD

+550

Anytime TD

-125

Travis Kelce (Chiefs)

First TD

+900

Anytime TD

+150

Isiah Pacheco (Chiefs)

First TD

+950

Anytime TD

+190

Marquise Brown (Chiefs)

First TD

+1000

Anytime TD

+170

AJ Brown (Eagles)

First TD

+1000

Anytime TD

+190

DeVonta Smith (Eagles)

First TD

+1200

Anytime TD

+210

Kareem Hunt (Chiefs)

First TD

+1500

Anytime TD

+250

JuJu Smith-Schuster (Chiefs)

First TD

+1800

Anytime TD

+340

Tyquan Thornton (Chiefs)

First TD

+1900

Anytime TD

+350

Patrick Mahomes (Chiefs)

First TD

+2000

Anytime TD

+400

Noah Gray (Chiefs)

First TD

+2500

Anytime TD

+480

Grant Calcaterra (Eagles)

First TD

+2700

Anytime TD

+600

Jahan Dotson (Eagles)

First TD

+4000

Anytime TD

+950

AJ Dillon (Eagles)

First TD

+6000

Anytime TD

+1300

Brashard Smith (Chiefs)

First TD

+7000

Anytime TD

+1300

Kylen Granson (Eagles)

First TD

+8000

Anytime TD

+1400

Jason Brownlee (Chiefs)

First TD

+10000

Anytime TD

+1400

John Metchie III (Eagles)

First TD

+10000

Anytime TD

+2200

Nikko Remigio (Chiefs)

First TD

+10000

Anytime TD

+2200

Robert Tonyan (Chiefs)

First TD

+10000

Anytime TD

+3300

Receiving Yards

AJ Brown (Eagles)

Over 76.5

-112

Under 76.5

-112

DeVonta Smith (Eagles)

Over 60.5

-112

Under 60.5

-112

Marquise Brown (Chiefs)

Over 58.5

-112

Under 58.5

-112

Travis Kelce (Chiefs)

Over 45.5

-112

Under 45.5

-112

JuJu Smith-Schuster (Chiefs)

Over 34.5

-112

Under 34.5

-112

Tyquan Thornton (Chiefs)

Over 31.5

-112

Under 31.5

-112

Grant Calcaterra (Eagles)

Over 21.5

-112

Under 21.5

-112

Noah Gray (Chiefs)

Over 17.5

-112

Under 17.5

-112

Saquon Barkley (Eagles)

Over 16.5

-112

Under 16.5

-112

Jahan Dotson (Eagles)

Over 11.5

-118

Under 11.5

-108

Kareem Hunt (Chiefs)

Over 8.5

-112

Under 8.5

-112

Isiah Pacheco (Chiefs)

Over 8.5

-118

Under 8.5

-108

Rushing Yards

Saquon Barkley (Eagles)

Over 87.5

-112

Under 87.5

-112

Jalen Hurts (Eagles)

Over 40.5

-112

Under 40.5

-112

Isiah Pacheco (Chiefs)

Over 39.5

-112

Under 39.5

-112

Patrick Mahomes (Chiefs)

Over 23.5

-112

Under 23.5

-112

Kareem Hunt (Chiefs)

Over 23.5

-112

Under 23.5

-112

Passing Yards

Patrick Mahomes (Chiefs)

Over 236.5

-112

Under 236.5

-112

Jalen Hurts (Eagles)

Over 212.5

-112

Under 212.5

-112

You don’t have to wait for the final outcome when it comes to NFL micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Can Chiefs Stay Hot at Home?

The Chiefs own a 10-0 mark in their past 10 home games, averaging 24.50 points scored and 19.20 points allowed.

The Eagles have gone 6-4 across their last 10 road games, putting up 24.30 points on average and giving up 20.50.

The last time the Eagles faced the Chiefs at GEHA Field at Arrowhead Stadium, they won 21-17.

Last 10 Games		W-L	P	PF	PA	O46.5	U46.5
Chiefs Home Stats		10-0	43.70	24.50	19.20	4	6
Eagles Away Stats		6-4	44.80	24.30	20.50	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O46.5 = Games Over 46.5 Points
• U46.5 = Games Under 46.5 Points

Latest regular season and playoff games stats.

Philadelphia Eagles Stats

Kansas City Chiefs Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• -1.5 Betting Line: Have covered the spread in 9 of the last 10 games
• -1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +1.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +1.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 49.40 pts in the previous 10 games
• Game Totals on the Road: An average of 44.80 pts in the previous 10 games on the road
• Over 46.5: Covered in 5 of the previous 10 games
• Over 46.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 31.20 pts and allowed 18.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 24.30 pts and allowed 20.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 43.10 pts in the previous 10 games
• Game Totals at Home: An average of 43.70 pts in the previous 10 home games
• Over 46.5: Covered in 3 of the previous 10 games
• Over 46.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 21.30 pts and allowed 21.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 24.50 pts and allowed 19.20 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 345.60 Yds. Allowed 297.50 Yds
• Rushing Yards: Gained 175.70 Yds. Allowed 100.00 Yds
• Passing Yards: Gained 169.90 Yds. Allowed 197.50 Yds
• Total Touchdowns: Scored 3.60 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 1.90 TD. Allowed 0.50 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.50 TD
• Total 1st Downs: Picked up 20.60. Allowed 16.90
• Total Turnovers: Committed 0.50. Committed by opponents 2.60
• Total Penalties: Committed 6.10. Committed by opponents 6.30
• Penalty Yards: Lost 48.70 Yds. Gained 58.40 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 300.20 Yds. Allowed 359.10 Yds
• Rushing Yards: Gained 84.30 Yds. Allowed 131.40 Yds
• Passing Yards: Gained 215.90 Yds. Allowed 227.70 Yds
• Total Touchdowns: Scored 2.30 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 17.80. Allowed 21.10
• Total Turnovers: Committed 0.40. Committed by opponents 1.20
• Total Penalties: Committed 5.90. Committed by opponents 6.50
• Penalty Yards: Lost 48.90 Yds. Gained 54.50 Yds

Last 10 Games on the Road

• Total Yards: Gained 341.70 Yds. Allowed 308.00 Yds
• Rushing Yards: Gained 174.30 Yds. Allowed 103.10 Yds
• Passing Yards: Gained 167.40 Yds. Allowed 204.90 Yds
• Total Touchdowns: Scored 2.80 TD. Allowed 2.30 TD
• Rushing Touchdowns: Scored 1.80 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 19.70. Allowed 19.50
• Total Turnovers: Committed 1.20. Committed by opponents 1.50
• Total Penalties: Committed 5.90. Committed by opponents 3.90
• Penalty Yards: Lost 47.20 Yds. Gained 32.00 Yds

Last 10 Home Games

• Total Yards: Gained 336.50 Yds. Allowed 327.90 Yds
• Rushing Yards: Gained 100.90 Yds. Allowed 106.80 Yds
• Passing Yards: Gained 235.60 Yds. Allowed 221.10 Yds
• Total Touchdowns: Scored 2.40 TD. Allowed 2.20 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 22.00. Allowed 19.00
• Total Turnovers: Committed 0.70. Committed by opponents 0.60
• Total Penalties: Committed 4.80. Committed by opponents 6.80
• Penalty Yards: Lost 39.20 Yds. Gained 62.40 Yds

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