49ers vs Texans Prediction, Picks & Odds | 26 Oct 2025

NFL Betting Preview: Niners vs Texans

The San Francisco 49ers battle the Houston Texans in this NFL Week 8 game at NRG Stadium, with kickoff scheduled for 12:00 on Sunday, October 26. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

The prediction is that the Texans will outscore the Niners, with odds of -139 currently available on the Moneyline. That looks a price worth taking on this value selection.

Backing Texans for the win? Take advantage of the exclusive BetMGM promo code and read our in-depth review for everything you need to know before betting.

San Francisco 49ers won their previous game which was at home. It was a 20-10 triumph at Levi's Stadium against Atlanta Falcons. The 49ers finished with 324 total yards, made up of 150 through the air and 174 on the ground. They managed 23 first downs and found the end zone twice, both times with rushing scores.

Houston Texans were beaten last game and this was on the road at Lumen Field. Seattle Seahawks claimed a 27-19 win. The Texans moved the ball for 254 yards, breaking down to 198 passing and 56 rushing yards. They picked up 18 first downs and found the end zone twice.

Head-to-Head Statistics

The last matchup between the Niners and the Texans saw the former win. It was a 23-7 scoreline at Levi's Stadium.

Quarterbacks

Mac Jones

219.5 Passing Yards

Over -112

Under -112

C.J. Stroud

215.5 Passing Yards

Over -112

Under -112

49ers vs Texans Prediction & Picks

Our 49ers vs Texans preview includes expert betting advice on all fronts — from a match prediction and correct score guidance to player prop selections and a bet builder tailored for value.

Game Prediction

It’s time to side with the Texans to record a victory in this NFL matchup. They should have the upper hand and the -139 for our pick on the Moneyline looks a good price.

Incoming team news often impacts the betting lines and odds in significant ways. Our NFL handicappers factor this in alongside recent form, while key stats are also carefully weighed to strengthen each pick.

Key 49ers vs Texans stats:

• Texans have won 14 of their last 20 games at home.
• Texans have won 6 of their last 10 games at home.
• 49ers have lost 11 of their last 20 games.

Texans Moneyline Probability

The best betting apps make it a 58.1% chance that our pick is settled as a winner. However, we have this figure between 65-70% based on our in-depth research. This is why we regard this as a value wager.

The Texans are available at a wide range of odds against the spread. If you are looking for more juice, then check out the latest betting lines and choose from the available options.

Make the most of your next wager by unlocking the best betting offers along with the latest sign-up bonuses and promotions.

Our Game Prediction

Texans Moneyline @ -139 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (18:26, 24 October 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Dalton Schultz Anytime TD +155

Dalton Schultz (Texans) can be backed at odds of +155 to hit paydirt. He looks like an attractive wager to take it to the house and we recommend backing this Anytime Touchdown Scorer selection.

Latest Dalton Schultz Player Prop Odds

Touchdown

Anytime

+155

First

+750

Receiving Yards

Over 48.5

-112

Under 48.5

-112

---

Mac Jones Over 219.5 Passing Yards -114

You can back Mac Jones (Niners) at -114 to exceed 219.5 passing yards. We can back him in the QB Passing Yards market and hope the Over hits.

Latest Mac Jones Player Prop Odds

Touchdown

Anytime

+1000

First

+4000

Passing Yards

Over 219.5

-112

Under 219.5

-112

Rushing Yards

Over 6.5

-112

Under 6.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

49ers 14 - 24 Texans

There’s the chance to bet on the Texans in lots of different ways and this includes predicting the correct winning score. We’ll go for a 24-14 victory in their favor.

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49ers vs Texans Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

If you want to bet on Houston Texans, then Moneyline odds of -100 are on offer, although San Francisco 49ers are a -120 chance. The sportsbook traders give the road team a 55% probability of success.

The spread is 1.5 and the total points line is currently 45.5. A bet on the Totals allows fans to use the latest NFL data to good effect. Those who wager Under 45.5 can get -105.

You’ll find a huge variety of game lines and team props for every matchup. The top NFL sportsbooks provide an impressive mix of pre-game and in-game options to suit your betting style.

Moneyline

49ers

-120

Texans

-100

Point Spread

49ers -1.5

-108

Texans +1.5

-112

Total Points

Under 45.5

-105

Over 45.5

-115

The Anytime Touchdown betting indicates that Christian McCaffrey has odds of %anytime_odds%. He is available at %first_odds% to score the first TD which makes him favorite.

Touchdown

Christian McCaffrey (49ers)

First TD

+390

Anytime TD

-141

Dalton Schultz (Texans)

First TD

+750

Anytime TD

+155

Woody Marks (Texans)

First TD

+750

Anytime TD

+165

George Kittle (49ers)

First TD

+800

Anytime TD

+150

Nick Chubb (Texans)

First TD

+1000

Anytime TD

+240

Xavier Hutchinson (Texans)

First TD

+1200

Anytime TD

+270

Ricky Pearsall (49ers)

First TD

+1300

Anytime TD

+270

Jauan Jennings (49ers)

First TD

+1300

Anytime TD

+290

Jayden Higgins (Texans)

First TD

+1400

Anytime TD

+310

Jaylin Noel (Texans)

First TD

+1500

Anytime TD

+320

Kendrick Bourne (49ers)

First TD

+2200

Anytime TD

+500

C.J. Stroud (Texans)

First TD

+3000

Anytime TD

+750

Harrison Bryant (Texans)

First TD

+3000

Anytime TD

+650

Braxton Berrios (Texans)

First TD

+3500

Anytime TD

+900

Mac Jones (49ers)

First TD

+4000

Anytime TD

+1000

Kyle Juszczyk (49ers)

First TD

+4500

Anytime TD

+1100

Brian Robinson Jr. (49ers)

First TD

+5000

Anytime TD

+1000

Demarcus Robinson (49ers)

First TD

+6000

Anytime TD

+1100

Jake Tonges (49ers)

First TD

+6000

Anytime TD

+1200

Dare Ogunbowale (Texans)

First TD

+6500

Anytime TD

+1500

Dameon Pierce (Texans)

First TD

+6500

Anytime TD

+1500

Luke Farrell (49ers)

First TD

+8000

Anytime TD

+1500

Jordan Watkins (49ers)

First TD

+10000

Anytime TD

+2500

British Brooks (Texans)

First TD

+10000

Anytime TD

+4000

Isaac Guerendo (49ers)

First TD

+10000

Anytime TD

+4000

James Jordan (49ers)

First TD

+10000

Anytime TD

+4000

Brenden Bates (Texans)

First TD

+10000

Anytime TD

+3000

Skyy Moore (49ers)

First TD

+10000

Anytime TD

+2700

Jared Wayne (Texans)

First TD

+10000

Anytime TD

+2500

Malik Turner (49ers)

First TD

+10000

Anytime TD

+3500

Receiving Yards

George Kittle (49ers)

Over 52.5

-112

Under 52.5

-112

Dalton Schultz (Texans)

Over 48.5

-112

Under 48.5

-112

Christian McCaffrey (49ers)

Over 47.5

-112

Under 47.5

-112

Jauan Jennings (49ers)

Over 41.5

-112

Under 41.5

-112

Jaylin Noel (Texans)

Over 36.5

-112

Under 36.5

-112

Kendrick Bourne (49ers)

Over 33.5

-112

Under 33.5

-112

Jayden Higgins (Texans)

Over 31.5

-112

Under 31.5

-112

Xavier Hutchinson (Texans)

Over 28.5

-112

Under 28.5

-112

Woody Marks (Texans)

Over 19.5

-112

Under 19.5

-112

Kyle Juszczyk (49ers)

Over 5.5

-112

Under 5.5

-112

Rushing Yards

Christian McCaffrey (49ers)

Over 66.5

-112

Under 66.5

-112

Woody Marks (Texans)

Over 37.5

-112

Under 37.5

-112

Nick Chubb (Texans)

Over 32.5

-112

Under 32.5

-112

C.J. Stroud (Texans)

Over 15.5

-112

Under 15.5

-112

Mac Jones (49ers)

Over 6.5

-112

Under 6.5

-112

Passing Yards

Mac Jones (49ers)

Over 219.5

-112

Under 219.5

-112

C.J. Stroud (Texans)

Over 215.5

-112

Under 215.5

-112

Instead of focusing on the overall outcome, some bettors prefer to look at the NFL micro betting lines. As the name suggests, it means placing short-term wagers and this might include the Next Play or Next Drive Result.

Texans Have Six Wins in Their Last Ten Home Games

The Texans are 6-4 in their last 10 home games, scoring 21.90 points per contest and conceding 19.30.

The Niners have five wins and five losses in the last 10 road games, averaging 20.80 points scored and 28.00 points allowed.

The last NRG Stadium meeting saw the Texans beat the Niners 17-0.

Last 10 Games		W-L	P	PF	PA	O41.5	U41.5
Texans Home Stats		6-4	41.20	21.90	19.30	6	4
49ers Away Stats		5-5	48.80	20.80	28.00	9	1

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O41.5 = Games Over 41.5 Points
• U41.5 = Games Under 41.5 Points

Latest regular season and playoff games stats.

San Francisco 49ers Stats

Houston Texans Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 47.40 pts in the previous 10 games
• Game Totals on the Road: An average of 48.80 pts in the previous 10 games on the road
• Over 41.5: Covered in 7 of the previous 10 games
• Over 41.5 on the Road: Covered in 9 of the previous 10 games on the road
• Team Totals: Have scored an average of 22.00 pts and allowed 25.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 20.80 pts and allowed 28.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 36.60 pts in the previous 10 games
• Game Totals at Home: An average of 41.20 pts in the previous 10 home games
• Over 41.5: Covered in 3 of the previous 10 games
• Over 41.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 19.80 pts and allowed 16.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 21.90 pts and allowed 19.30 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 385.10 Yds. Allowed 342.70 Yds
• Rushing Yards: Gained 96.10 Yds. Allowed 117.70 Yds
• Passing Yards: Gained 289.00 Yds. Allowed 225.00 Yds
• Total Touchdowns: Scored 2.30 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.70 TD. Allowed 1.90 TD
• Total 1st Downs: Picked up 23.00. Allowed 20.50
• Total Turnovers: Committed 1.70. Committed by opponents 0.60
• Total Penalties: Committed 7.30. Committed by opponents 5.80
• Penalty Yards: Lost 56.30 Yds. Gained 41.20 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 317.60 Yds. Allowed 286.40 Yds
• Rushing Yards: Gained 121.90 Yds. Allowed 100.70 Yds
• Passing Yards: Gained 195.70 Yds. Allowed 185.70 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 1.90 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.10 TD. Allowed 0.90 TD
• Total 1st Downs: Picked up 17.40. Allowed 16.90
• Total Turnovers: Committed 1.10. Committed by opponents 1.50
• Total Penalties: Committed 7.10. Committed by opponents 6.40
• Penalty Yards: Lost 63.70 Yds. Gained 48.90 Yds

Last 10 Games on the Road

• Total Yards: Gained 368.40 Yds. Allowed 338.10 Yds
• Rushing Yards: Gained 105.60 Yds. Allowed 125.70 Yds
• Passing Yards: Gained 262.80 Yds. Allowed 212.40 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 3.40 TD
• Rushing Touchdowns: Scored 0.40 TD. Allowed 1.40 TD
• Passing Touchdowns: Scored 1.70 TD. Allowed 1.90 TD
• Total 1st Downs: Picked up 20.80. Allowed 21.10
• Total Turnovers: Committed 1.60. Committed by opponents 0.80
• Total Penalties: Committed 7.70. Committed by opponents 5.20
• Penalty Yards: Lost 55.50 Yds. Gained 37.80 Yds

Last 10 Home Games

• Total Yards: Gained 317.10 Yds. Allowed 305.80 Yds
• Rushing Yards: Gained 90.30 Yds. Allowed 131.20 Yds
• Passing Yards: Gained 226.80 Yds. Allowed 174.60 Yds
• Total Touchdowns: Scored 2.20 TD. Allowed 2.10 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 16.70. Allowed 18.10
• Total Turnovers: Committed 1.30. Committed by opponents 1.90
• Total Penalties: Committed 7.10. Committed by opponents 5.30
• Penalty Yards: Lost 59.90 Yds. Gained 40.70 Yds

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