49ers vs Eagles Prediction, Picks & Odds | 11 Jan 2026

NFL Playoff Wild Card Weekend Betting Preview: Niners vs Eagles

No. 6 San Francisco 49ers square off against No. 3 Philadelphia Eagles in this NFC Wild Card Weekend showdown at Lincoln Financial Field, with kickoff scheduled for 16:30 on Sunday, January 11.

The best wager could involve backing San Francisco against the spread. There’s an attractive +5.5 available at -108 that the Niners cover the line against the Eagles and that has to be our pick.

Trusting our spread pick? Read our expert BetMGM review, then take advantage of the best promo code before placing your bet.

The San Francisco 49ers (12-5, 2nd in NFC West) come into this Wild Card matchup having won four straight games on the road, though they lost 13–3 at home to the Seattle Seahawks at Levi’s Stadium in their most recent outing. The Niners totaled 173 yards of offense, with 120 coming through the air and 53 on the ground. They recorded nine first downs while allowing 23.

The Philadelphia Eagles (11-6, 1st in NFC East) ended the regular season with a 24–17 home loss to the Washington Commanders at Lincoln Financial Field. The Eagles moved the ball for 307 yards, with 227 through the air and 80 on the ground. The offense managed 18 first downs and scored 2 touchdowns, one on the ground and one through the air.

Head-to-Head Statistics

Although San Francisco dominated the most recent meeting 42–19 at Lincoln Financial Field, the last four matchups between these teams are split 2–2.

Quarterbacks

Brock Purdy

221.5 Passing Yards

Over -114

Under -114

Jalen Hurts

208.5 Passing Yards

Over -114

Under -114

49ers vs Eagles Prediction & Picks

Join us as we dissect the top 49ers vs Eagles betting picks — from the main match prediction and scoreline forecast to standout player props and a value-focused bet builder.

Game Prediction

We’re confident that the Niners can produce a strong performance in this Wild Card battle. Our pick is that the underdogs will cover the +5.5 line and you can currently get -108.

Our NFL predictions are built after tracking the latest team news and reviewing recent form. We also dive into up-to-date stats, which often serve as a solid barometer for how the action might unfold.

Key 49ers vs Eagles stats:

• The +5.5 line has been covered by 49ers in 4 consecutive games on the road.
• The +5.5 line has been covered by 49ers in 7 of their 9 games on the road this season.
• The +5.5 line has been covered by 49ers in 13 of their 17 games this season.
• The -5.5 line hasn’t been covered by Eagles in 6 of their last 10 games.
• The -5.5 line hasn’t been covered by Eagles in 3 of their last 5 games.
• The -5.5 line hasn’t been covered by Eagles in 2 consecutive games.
• The -5.5 line hasn’t been covered by Eagles in 3 of their last 4 games against 49ers.

Niners +5.5 Probability

The best betting apps imply that our pick has a 51.8% chance of winning. After careful examination, our analysts calculate this probability to be closer to 60%. That means we are regarding it as a value wager.

If you want to secure a bigger possible payout on your wager, there’s the possibility to move the line. Take a look at the various odds and see which spread you think will be covered.

Give your betting journey a head start. Explore the latest welcome offers and free bets in our easy-to-follow guide.

Our Game Prediction

49ers +5.5 @ -108 Watch Live Bet Now

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Player Prop Picks

Top Pick: Brock Purdy Over 221.5 Passing Yards -114

Brock Purdy (Niners) is priced at -114 to rack up over 221.5 passing yards. The line for him on the Overs is highly appealing, with QB Passing Yards bettors able to get plenty of juice.

Latest Brock Purdy Player Prop Odds

Touchdown

Anytime

+600

First

+3000

Passing Yards

Over 221.5

-114

Under 221.5

-114

Rushing Yards

Over 17.5

-114

Under 17.5

-114

---

George Kittle Over 59.5 Receiving Yards -114

The odds for George Kittle (Eagles) to rack up over 59.5 receiving yards stand at -114. We can back him in the Player Receiving Yards market and hope the Over hits.

Latest George Kittle Player Prop Odds

Touchdown

Anytime

+190

First

+1000

Receiving Yards

Over 57.5

-114

Under 57.5

-114

Correct Score Prediction

49ers 23 - 27 Eagles

There might not be too much between these teams, with our correct score prediction being a 27-23 win for the Eagles. There are enormous odds available when it comes to this pick.

49ers vs Eagles Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

The sportsbooks’ betting odds have Philadelphia Eagles as -278 favorites for this game, implying that the Birds are 74% likely to win. San Francisco 49ers are regarded as a long shot to win and you can currently back them at +225.

The spread is currently 5.5, with the total points line at 44.5. The advantage of the Totals is that you only have to choose from one of two options. If you want to bet Under 44.5, there are odds of -115.

There’s a wide variety of game lines and team props available and we recommend checking out the best NFL betting sites to find the markets that align with your take on the matchup.

Moneyline

49ers

+225

Eagles

-278

Point Spread

49ers +5.5

-102

Eagles -5.5

-120

Total Points

Under 44.5

-115

Over 44.5

-105

Saquon Barkley can be backed to score a touchdown at anytime at -135. He is the favorite to score the first TD at odds of +460.

Touchdown

Saquon Barkley (Eagles)

First TD

+460

Anytime TD

-135

Christian McCaffrey (49ers)

First TD

+500

Anytime TD

-130

Jalen Hurts (Eagles)

First TD

+600

Anytime TD

+105

AJ Brown (Eagles)

First TD

+700

Anytime TD

+150

DeVonta Smith (Eagles)

First TD

+950

Anytime TD

+195

Dallas Goedert (Eagles)

First TD

+950

Anytime TD

+190

George Kittle (49ers)

First TD

+1000

Anytime TD

+190

Jauan Jennings (49ers)

First TD

+1500

Anytime TD

+270

Ricky Pearsall (49ers)

First TD

+2200

Anytime TD

+430

Demarcus Robinson (49ers)

First TD

+2200

Anytime TD

+430

Jahan Dotson (Eagles)

First TD

+3000

Anytime TD

+650

Brock Purdy (49ers)

First TD

+3000

Anytime TD

+600

Brian Robinson Jr. (49ers)

First TD

+4000

Anytime TD

+900

Kyle Juszczyk (49ers)

First TD

+5500

Anytime TD

+1200

Kendrick Bourne (49ers)

First TD

+5500

Anytime TD

+750

Tank Bigsby (Eagles)

First TD

+6000

Anytime TD

+800

Jake Tonges (49ers)

First TD

+7000

Anytime TD

+950

Luke Farrell (49ers)

First TD

+7000

Anytime TD

+950

Cameron Latu (Eagles)

First TD

+8000

Anytime TD

+1000

Grant Calcaterra (Eagles)

First TD

+8000

Anytime TD

+1000

Kylen Granson (Eagles)

First TD

+8000

Anytime TD

+1000

AJ Dillon (Eagles)

First TD

+10000

Anytime TD

+1900

Jordan Watkins (49ers)

First TD

+10000

Anytime TD

+2700

Skyy Moore (49ers)

First TD

+10000

Anytime TD

+2700

Will Shipley (Eagles)

First TD

+10000

Anytime TD

+1900

Darius Cooper (Eagles)

First TD

+10000

Anytime TD

+1300

Britain Covey (Eagles)

First TD

+10000

Anytime TD

+2500

Isaac Guerendo (49ers)

First TD

+10000

Anytime TD

+3500

James Jordan (49ers)

First TD

+10000

Anytime TD

+3500

Receiving Yards

AJ Brown (Eagles)

Over 67.5

-114

Under 67.5

-114

George Kittle (49ers)

Over 57.5

-114

Under 57.5

-114

DeVonta Smith (Eagles)

Over 55.5

-114

Under 55.5

-114

Jauan Jennings (49ers)

Over 45.5

-114

Under 45.5

-114

Christian McCaffrey (49ers)

Over 45.5

-114

Under 45.5

-114

Dallas Goedert (Eagles)

Over 39.5

-114

Under 39.5

-114

Ricky Pearsall (49ers)

Over 38.5

-114

Under 38.5

-114

Saquon Barkley (Eagles)

Over 15.5

-114

Under 15.5

-114

Jahan Dotson (Eagles)

Over 7.5

-122

Under 7.5

-108

Kyle Juszczyk (49ers)

Over 6.5

-114

Under 6.5

-114

Rushing Yards

Saquon Barkley (Eagles)

Over 79.5

-114

Under 79.5

-114

Christian McCaffrey (49ers)

Over 59.5

-114

Under 59.5

-114

Jalen Hurts (Eagles)

Over 31.5

-114

Under 31.5

-114

Brock Purdy (49ers)

Over 17.5

-114

Under 17.5

-114

Brian Robinson Jr. (49ers)

Over 11.5

-114

Under 11.5

-114

Passing Yards

Brock Purdy (49ers)

Over 221.5

-114

Under 221.5

-114

Jalen Hurts (Eagles)

Over 208.5

-114

Under 208.5

-114

Eagles Hold Seven Wins in Previous Ten at Home

The Eagles have a 7-3 record in their last 10 home games, posting 27.40 points per contest while yielding 18.90.

The Niners are riding four straight road wins. They own a 7-3 mark in their past 10 road games, averaging 27.60 points on offense and surrendering 24.10 on defense.

When the teams last met at Lincoln Financial Field, the Niners beat the Eagles 42-19. Over the last 3 head-to-head clashes at Lincoln Financial Field, the Niners have recorded two wins, while the Eagles have one to their name.

Last 10 Games		W-L	P	PF	PA	O44.5	U44.5
Eagles Home Stats		7-3	46.30	27.40	18.90	4	6
49ers Away Stats		7-3	51.70	27.60	24.10	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O44.5 = Games Over 44.5 Points
• U44.5 = Games Under 44.5 Points

Latest regular season and playoff games stats.

San Francisco 49ers Stats

Philadelphia Eagles Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +5.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +5.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -5.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -5.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 52.50 pts in the previous 10 games
• Game Totals on the Road: An average of 51.70 pts in the previous 10 games on the road
• Over 44.5: Covered in 6 of the previous 10 games
• Over 44.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 29.20 pts and allowed 23.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 27.60 pts and allowed 24.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 36.90 pts in the previous 10 games
• Game Totals at Home: An average of 47.50 pts in the previous 10 home games
• Over 44.5: Covered in 3 of the previous 10 games
• Over 44.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 20.90 pts and allowed 16.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 28.60 pts and allowed 18.90 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 340.20 Yds. Allowed 356.20 Yds
• Rushing Yards: Gained 114.40 Yds. Allowed 112.70 Yds
• Passing Yards: Gained 225.80 Yds. Allowed 243.50 Yds
• Total Touchdowns: Scored 3.60 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 1.20 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 2.30 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 22.30. Allowed 21.00
• Total Turnovers: Committed 1.10. Committed by opponents 1.00
• Total Penalties: Committed 3.90. Committed by opponents 6.30
• Penalty Yards: Lost 29.30 Yds. Gained 42.90 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 328.30 Yds. Allowed 289.70 Yds
• Rushing Yards: Gained 137.10 Yds. Allowed 122.00 Yds
• Passing Yards: Gained 191.20 Yds. Allowed 167.70 Yds
• Total Touchdowns: Scored 2.40 TD. Allowed 1.80 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 1.10 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 0.70 TD
• Total 1st Downs: Picked up 18.60. Allowed 18.00
• Total Turnovers: Committed 1.20. Committed by opponents 1.40
• Total Penalties: Committed 6.80. Committed by opponents 5.10
• Penalty Yards: Lost 61.70 Yds. Gained 42.30 Yds

Last 10 Games on the Road

• Total Yards: Gained 350.40 Yds. Allowed 355.30 Yds
• Rushing Yards: Gained 100.70 Yds. Allowed 104.50 Yds
• Passing Yards: Gained 249.70 Yds. Allowed 250.80 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.90 TD
• Rushing Touchdowns: Scored 0.80 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 2.20 TD. Allowed 2.10 TD
• Total 1st Downs: Picked up 22.40. Allowed 20.70
• Total Turnovers: Committed 1.10. Committed by opponents 1.30
• Total Penalties: Committed 6.00. Committed by opponents 6.20
• Penalty Yards: Lost 42.10 Yds. Gained 42.50 Yds

Last 10 Home Games

• Total Yards: Gained 340.60 Yds. Allowed 298.30 Yds
• Rushing Yards: Gained 142.70 Yds. Allowed 116.90 Yds
• Passing Yards: Gained 197.90 Yds. Allowed 181.40 Yds
• Total Touchdowns: Scored 3.60 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 1.60 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.80 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 20.20. Allowed 18.60
• Total Turnovers: Committed 0.50. Committed by opponents 1.40
• Total Penalties: Committed 6.90. Committed by opponents 5.90
• Penalty Yards: Lost 61.40 Yds. Gained 52.10 Yds

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