49ers vs Seahawks Prediction, Picks & Odds | 17 Jan 2026

NFL Playoff Divisional Round Betting Preview: Niners vs Seahawks

No. 6 San Francisco 49ers go up against No. 1 Seattle Seahawks in this NFC Divisional Round showdown at Lumen Field, with kickoff scheduled for 20:00 on Saturday, January 17.

We’re confident that the underdogs can either win or suffer a narrow defeat. That makes the Niners at +7 the best wager when they clash with the Seahawks and odds of -112 are available.

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The San Francisco 49ers (12-5, 2nd in NFC West) advanced to this Divisional Round game on the back of five straight road wins, including a 23–19 victory over the Philadelphia Eagles in the Wild Card round at Lincoln Financial Field.

The Niners moved the ball for 361 yards, including 286 passing and 75 rushing yards. They produced 20 first downs along with 3 touchdowns.

The Seattle Seahawks (14-3, 1st in NFC West) come into this matchup off a bye and riding a seven-game winning streak, highlighted by a 13–3 road win over today’s opponents, the San Francisco 49ers, in the regular season finale.

The Hawks moved the ball for 361 yards, made up of 181 through the air and 180 on the ground. Their output included 23 first downs and one touchdown on the ground.

Head-to-Head Statistics

The last meeting between the Seahawks and 49ers saw Seattle come out on top, earning a 13–3 win at Levi’s Stadium two weeks ago. However, San Francisco has won seven of the past 10 matchups between these teams.

Quarterbacks

Brock Purdy

227.5 Passing Yards

Over -114

Under -114

Sam Darnold

233.5 Passing Yards

Over -114

Under -114

49ers vs Seahawks Prediction & Picks

Take on 49ers vs Seahawks with our in-depth betting analysis, featuring an expert match prediction, scoreline advice, key player props and a value-driven bet builder.

Game Prediction

The best wager could involve backing the Niners against the spread in this NFL showdown. There’s an attractive +7 available at -112 that they cover the line and that has to be our pick.

Knowing which players are injured gives us a valuable edge when making NFL picks. After reviewing the form guide, we turn to the latest stats to shape our predictions.

Key 49ers vs Seahawks stats:

• The +7 line has been covered by 49ers in 5 consecutive games on the road.
• The +7 line has been covered by 49ers in 8 of their last 10 games.
• The +7 line has been covered by 49ers in 14 of their last 18 games this season.
• The -7 line hasn’t been covered by Seahawks in 14 of their last 20 games at home.
• The -7 line hasn’t been covered by Seahawks in 6 of their last 10 games at home.
• The -7 line hasn’t been covered by Seahawks in 2 consecutive games at home.
• The -7 line hasn’t been covered by Seahawks in 8 of their last 10 games against 49ers.

Niners +7 Probability

When you look at the latest betting odds, our pick has a 52.9% chance of winning. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. This is why we can recommend this bet.

If you want to pimp the odds about the Niners against the spread, you might consider going down the Bet Builder route and combine this pick with other selections.

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Our Game Prediction

49ers +7 @ -112 Watch Live Bet Now

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Player Prop Picks

Top Pick: Christian McCaffrey Anytime TD -125

Christian McCaffrey (Niners) is available at -125 to reach the end zone. Attractive odds are available for this Anytime Touchdown Scorer wager, and we believe it's a value proposition for him to take it to the house.

Latest Christian McCaffrey Player Prop Odds

Touchdown

Anytime

-125

First

+550

Receiving Yards

Over 51.5

-114

Under 51.5

-114

Rushing Yards

Over 54.5

-114

Under 54.5

-114

---

Sam Darnold Over 233.5 Passing Yards -114

The odds for Sam Darnold (Hawks) to record more than 233.5 passing yards are -114. We’re tempted to back him to cover the QB Passing Yards line, with plenty of juice on offer.

Latest Sam Darnold Player Prop Odds

Touchdown

Anytime

+800

First

+3300

Passing Yards

Over 233.5

-114

Under 233.5

-114

Rushing Yards

Over 6.5

-114

Under 6.5

-114

Correct Score Prediction

49ers 23 - 27 Seahawks

We’re expecting a close matchup so it might be worth going for the Hawks to win by a 27-23 scoreline. You can get a huge price and we should hopefully get a run for our money.

49ers vs Seahawks Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

The sportsbooks have Seattle Seahawks at -333 when it comes to the Moneyline betting, implying the market leaders are 77% likely to win this game according to the latest odds. For those wanting to back San Francisco 49ers, you will find +270 about the underdogs.

The current spread is 7 and total points is 44.5. Having a wager on the Totals is one of the most popular NFL bets. If you fancy Over 44.5, this outcome can be backed at -112.

National Football League fans are spoilt for choice thanks to the wide range of game lines and team props which are available for every game on the coupon. Visit the top betting apps and find the best value wagers.

Moneyline

49ers

+270

Seahawks

-333

Point Spread

49ers +7

-112

Seahawks -7

-108

Total Points

Under 44.5

-108

Over 44.5

-112

The First Touchdown Scorer favorite is Jaxon Smith-Njigba at +500. Similar odds can be found if you’re interested in this player to register the final TD.

Touchdown

Jaxon Smith-Njigba (Seahawks)

First TD

+500

Anytime TD

-100

Christian McCaffrey (49ers)

First TD

+550

Anytime TD

-125

Zach Charbonnet (Seahawks)

First TD

+550

Anytime TD

-115

Kenneth Walker III (Seahawks)

First TD

+600

Anytime TD

+120

AJ Barner (Seahawks)

First TD

+850

Anytime TD

+170

Jauan Jennings (49ers)

First TD

+1300

Anytime TD

+230

Cooper Kupp (Seahawks)

First TD

+1500

Anytime TD

+320

Jake Tonges (49ers)

First TD

+1700

Anytime TD

+310

Rashid Shaheed (Seahawks)

First TD

+1800

Anytime TD

+390

Demarcus Robinson (49ers)

First TD

+1900

Anytime TD

+320

Ricky Pearsall (49ers)

First TD

+1900

Anytime TD

+320

Elijah Arroyo (Seahawks)

First TD

+2500

Anytime TD

+650

Brock Purdy (49ers)

First TD

+3000

Anytime TD

+700

Sam Darnold (Seahawks)

First TD

+3300

Anytime TD

+800

Kyle Juszczyk (49ers)

First TD

+3500

Anytime TD

+750

Eric Saubert (Seahawks)

First TD

+4000

Anytime TD

+650

Brian Robinson Jr. (49ers)

First TD

+6000

Anytime TD

+1100

Kendrick Bourne (49ers)

First TD

+6500

Anytime TD

+1000

Luke Farrell (49ers)

First TD

+8000

Anytime TD

+1000

Jake Bobo (Seahawks)

First TD

+10000

Anytime TD

+3000

Skyy Moore (49ers)

First TD

+10000

Anytime TD

+2500

Robbie Ouzts (Seahawks)

First TD

+10000

Anytime TD

+3500

Malik Turner (49ers)

First TD

+10000

Anytime TD

+4500

Dareke Young (Seahawks)

First TD

+10000

Anytime TD

+4000

Brady Russell (Seahawks)

First TD

+10000

Anytime TD

+5000

Nick Kallerup (Seahawks)

First TD

+10000

Anytime TD

+2200

Receiving Yards

Jaxon Smith-Njigba (Seahawks)

Over 94.5

-114

Under 94.5

-114

Christian McCaffrey (49ers)

Over 51.5

-114

Under 51.5

-114

Jauan Jennings (49ers)

Over 40.5

-114

Under 40.5

-114

Jake Tonges (49ers)

Over 37.5

-114

Under 37.5

-114

AJ Barner (Seahawks)

Over 31.5

-114

Under 31.5

-114

Cooper Kupp (Seahawks)

Over 30.5

-114

Under 30.5

-114

Rashid Shaheed (Seahawks)

Over 23.5

-114

Under 23.5

-114

Kyle Juszczyk (49ers)

Over 14.5

-114

Under 14.5

-114

Kenneth Walker III (Seahawks)

Over 13.5

-114

Under 13.5

-114

Zach Charbonnet (Seahawks)

Over 9.5

-114

Under 9.5

-114

Elijah Arroyo (Seahawks)

Over 7.5

-108

Under 7.5

-122

Rushing Yards

Kenneth Walker III (Seahawks)

Over 58.5

-114

Under 58.5

-114

Christian McCaffrey (49ers)

Over 54.5

-114

Under 54.5

-114

Zach Charbonnet (Seahawks)

Over 46.5

-114

Under 46.5

-114

Brock Purdy (49ers)

Over 17.5

-114

Under 17.5

-114

Sam Darnold (Seahawks)

Over 6.5

-114

Under 6.5

-114

Rashid Shaheed (Seahawks)

Over 2.5

+120

Under 2.5

-161

Passing Yards

Sam Darnold (Seahawks)

Over 233.5

-114

Under 233.5

-114

Brock Purdy (49ers)

Over 227.5

-114

Under 227.5

-114

Hawks Locked In at Home

The Seahawks have stacked up five straight victories at Lumen Field. They have six wins and four losses in the last 10 games at home, averaging 28.20 points scored and 21.90 points allowed.

The Niners have posted five consecutive road victories. They own a 8-2 mark in their past 10 games on the road, putting up 27.50 points per contest and giving up 21.30.

In their last matchup at Lumen Field, the Niners came out on top 17-13 against the Hawks. Across the last 7 head-to-head meetings at Lumen Field, the Niners have come out on top five times, with the Hawks having two wins.

Last 10 Games		W-L	P	PF	PA	O44.5	U44.5
Seahawks Home Stats		6-4	50.10	28.20	21.90	6	4
49ers Away Stats		8-2	48.80	27.50	21.30	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O44.5 = Games Over 44.5 Points
• U44.5 = Games Under 44.5 Points

Latest regular season and playoff games stats.

San Francisco 49ers Stats

Seattle Seahawks Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +7 Betting Line: Have covered the spread in 8 of the last 10 games
• +7 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -7 Betting Line: Have covered the spread in 6 of the last 10 games
• -7 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 52.60 pts in the previous 10 games
• Game Totals on the Road: An average of 48.80 pts in the previous 10 games on the road
• Over 44.5: Covered in 6 of the previous 10 games
• Over 44.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 30.00 pts and allowed 22.60 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 27.50 pts and allowed 21.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 44.60 pts in the previous 10 games
• Game Totals at Home: An average of 50.10 pts in the previous 10 home games
• Over 44.5: Covered in 5 of the previous 10 games
• Over 44.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 29.00 pts and allowed 15.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 28.20 pts and allowed 21.90 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 354.00 Yds. Allowed 339.40 Yds
• Rushing Yards: Gained 117.10 Yds. Allowed 111.00 Yds
• Passing Yards: Gained 236.90 Yds. Allowed 228.40 Yds
• Total Touchdowns: Scored 3.70 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 1.20 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 2.40 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 23.10. Allowed 20.60
• Total Turnovers: Committed 1.20. Committed by opponents 0.90
• Total Penalties: Committed 3.60. Committed by opponents 6.20
• Penalty Yards: Lost 27.80 Yds. Gained 42.20 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 351.90 Yds. Allowed 271.40 Yds
• Rushing Yards: Gained 135.30 Yds. Allowed 102.80 Yds
• Passing Yards: Gained 216.60 Yds. Allowed 168.60 Yds
• Total Touchdowns: Scored 2.90 TD. Allowed 1.70 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 0.90 TD
• Total 1st Downs: Picked up 20.40. Allowed 15.50
• Total Turnovers: Committed 1.60. Committed by opponents 1.70
• Total Penalties: Committed 5.40. Committed by opponents 6.40
• Penalty Yards: Lost 40.40 Yds. Gained 48.50 Yds

Last 10 Games on the Road

• Total Yards: Gained 342.90 Yds. Allowed 346.70 Yds
• Rushing Yards: Gained 94.40 Yds. Allowed 103.40 Yds
• Passing Yards: Gained 248.50 Yds. Allowed 243.30 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 2.30 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 21.80. Allowed 20.00
• Total Turnovers: Committed 1.00. Committed by opponents 1.30
• Total Penalties: Committed 4.80. Committed by opponents 6.80
• Penalty Yards: Lost 35.10 Yds. Gained 46.80 Yds

Last 10 Home Games

• Total Yards: Gained 321.50 Yds. Allowed 330.80 Yds
• Rushing Yards: Gained 109.40 Yds. Allowed 94.70 Yds
• Passing Yards: Gained 212.10 Yds. Allowed 236.10 Yds
• Total Touchdowns: Scored 3.00 TD. Allowed 2.30 TD
• Rushing Touchdowns: Scored 1.20 TD. Allowed 0.50 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 19.50. Allowed 20.00
• Total Turnovers: Committed 2.10. Committed by opponents 1.30
• Total Penalties: Committed 6.40. Committed by opponents 7.20
• Penalty Yards: Lost 55.30 Yds. Gained 56.20 Yds

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