Buccaneers vs Panthers Prediction, Picks & Odds | 21 Dec 2025

NFL Betting Preview: Buccaneers vs Panthers

The Tampa Bay Buccaneers square off against the Carolina Panthers at Bank of America Stadium, with kickoff scheduled for 13:00 on Sunday, December 21.

Our prediction is that the Panthers will be able to cover the spread against the Buccaneers, with +3 looking favorable for our bet. Take the -110 that is currently available.

Feeling good about our spread pick? Don’t miss the new BetMGM promo code and our expert review as you get ready to make your move.

Tampa Bay Buccaneers suffered a second consecutive defeat when losing 29-28 in their previous game. This was at home to Atlanta Falcons at Raymond James Stadium. The Buccaneers moved the ball for 338 yards, made up of 250 through the air and 88 on the ground. The offense converted for 28 first downs along with 3 touchdowns.

Carolina Panthers lost on the road in their last game. New Orleans Saints won 20-17 at Caesars Superdome. The Panthers recorded 281 total yards, made up of 154 through the air and 127 on the ground. The offense managed 15 first downs to go along with two touchdowns.

Head-to-Head Statistics

The Bucs won the most recent matchup between these teams. A 48-14 victory was registered against the Panthers at Raymond James Stadium. In the past 10 games between the teams, the Bucs have won nine.

Quarterbacks

Baker Mayfield

228.5 Passing Yards

Over -114

Under -114

Bryce Young

204.5 Passing Yards

Over -114

Under -114

Buccaneers vs Panthers Prediction & Picks

Approach Buccaneers vs Panthers fully prepared with our expert match prediction, likely score outcome, standout player prop picks and a hand-picked bet builder.

Game Prediction

There’s a good opportunity to back the Panthers against the spread considering the underdogs should perform well in this NFL showdown. Snap up the -110 when it comes to them covering the +3.

We only publish our NFL predictions once we’ve got a clear and confident read on team news and the latest form. We also stay sharp by digging into the most valuable stats to support every pick we make.

Key Buccaneers vs Panthers stats:

• The +3 line has been covered by Panthers in 7 of their last 10 games.
• The +3 line has been covered by Panthers in 4 of their last 6 games at home this season.
• The +3 line has been covered by Panthers in 2 consecutive games.
• The -3 line hasn’t been covered by Buccaneers in 4 of their last 5 games.
• The -3 line hasn’t been covered by Buccaneers in 9 of their last 14 games this season.
• The -3 line hasn’t been covered by Buccaneers in 2 consecutive games.

Panthers +3 Probability

The top NFL sportsbooks are estimating that there is a 52.4% chance of this pick winning. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. It’s why we think it’s worth placing this wager.

If you want to back the Panthers without taking them against the spread, there’s the alternative to go for a Winning Margin wager instead. There are lots of different options here.

Get the most from your next wager. Check our expert guide filled with the best free bets and top bonus offers.

Our Game Prediction

Panthers +3 @ -110 Watch Live Bet Now

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Player Prop Picks

Top Pick: Bucky Irving Anytime TD +145

Bucky Irving (Bucs) is available at +145 to score a TD. The Anytime Touchdown Scorer odds are appealing from all angles and we’re willing to take a chance on him.

Latest Bucky Irving Player Prop Odds

Touchdown

Anytime

+145

First

+700

Receiving Yards

Over 17.5

-114

Under 17.5

-114

Rushing Yards

Over 64.5

-114

Under 64.5

-114

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Mike Evans Under 61.5 Receiving Yards -114

Mike Evans (Panthers) is priced at -114 to record fewer than 61.5 receiving yards. We're confident he’ll fall short of the Player Receiving Yards line, so we're backing the Under.

Latest Mike Evans Player Prop Odds

Touchdown

Anytime

+175

First

+900

Receiving Yards

Over 61.5

-114

Under 61.5

-114

Correct Score Prediction

Buccaneers 20 - 21 Panthers

We’re expecting this to be a close battle and we’ll take the Panthers to win 21-20. This is available at huge odds for those that want to have a speculative wager.

Buccaneers vs Panthers Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Tampa Bay Buccaneers are regarded as having a 62% chance of winning this game according to the latest betting odds. The sportsbooks have priced them up at -161. For those wanting to oppose the market leader, you can get +136 about Carolina Panthers.

The spread is 3 and the total points line is currently 45.5. A bet on the Totals allows fans to use the latest NFL data to good effect. There’s the chance to back Under 45.5 at -110.

If a National Football League wager is on your mind, visit the top sportsbooks and check out the huge selection of available game lines and team props. Find the betting odds and lines which are the most appealing.

Moneyline

Buccaneers

-161

Panthers

+136

Point Spread

Buccaneers -3

-110

Panthers +3

-110

Total Points

Under 45.5

-110

Over 45.5

-110

Bucky Irving is available at +145 when it comes to Anytime Touchdown Scorer. The favorite is now priced at odds of +700 to score the first TD.

Touchdown

Bucky Irving (Buccaneers)

First TD

+700

Anytime TD

+145

Rico Dowdle (Panthers)

First TD

+700

Anytime TD

+125

Mike Evans (Buccaneers)

First TD

+900

Anytime TD

+175

Tetairoa McMillan (Panthers)

First TD

+950

Anytime TD

+155

Emeka Egbuka (Buccaneers)

First TD

+950

Anytime TD

+220

Chuba Hubbard (Panthers)

First TD

+1200

Anytime TD

+200

Sean Tucker (Buccaneers)

First TD

+1200

Anytime TD

+210

Chris Godwin (Buccaneers)

First TD

+1400

Anytime TD

+290

Cade Otton (Buccaneers)

First TD

+1500

Anytime TD

+310

Jalen Coker (Panthers)

First TD

+1600

Anytime TD

+300

Xavier Legette (Panthers)

First TD

+1800

Anytime TD

+310

Ja'Tavion Sanders (Panthers)

First TD

+2000

Anytime TD

+400

Jalen McMillan (Buccaneers)

First TD

+2200

Anytime TD

+430

Baker Mayfield (Buccaneers)

First TD

+2700

Anytime TD

+600

Bryce Young (Panthers)

First TD

+3000

Anytime TD

+650

Rachaad White (Buccaneers)

First TD

+3500

Anytime TD

+440

Tommy Tremble (Panthers)

First TD

+5500

Anytime TD

+900

Sterling Shepard (Buccaneers)

First TD

+8000

Anytime TD

+1200

Payne Durham (Buccaneers)

First TD

+8000

Anytime TD

+1300

Brycen Tremayne (Panthers)

First TD

+8000

Anytime TD

+1400

James Mitchell (Panthers)

First TD

+8000

Anytime TD

+1400

Mitchell Evans (Panthers)

First TD

+8000

Anytime TD

+1200

Tez Johnson (Buccaneers)

First TD

+8000

Anytime TD

+1200

Jimmy Horn Jr. (Panthers)

First TD

+10000

Anytime TD

+1500

Devin Culp (Buccaneers)

First TD

+10000

Anytime TD

+3000

Trevor Etienne (Panthers)

First TD

+10000

Anytime TD

+2200

Kameron Johnson (Buccaneers)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Mike Evans (Buccaneers)

Over 61.5

-114

Under 61.5

-114

Tetairoa McMillan (Panthers)

Over 56.5

-114

Under 56.5

-114

Emeka Egbuka (Buccaneers)

Over 41.5

-114

Under 41.5

-114

Jalen Coker (Panthers)

Over 37.5

-114

Under 37.5

-114

Chris Godwin (Buccaneers)

Over 32.5

-114

Under 32.5

-114

Jalen McMillan (Buccaneers)

Over 21.5

-114

Under 21.5

-114

Cade Otton (Buccaneers)

Over 21.5

-114

Under 21.5

-114

Xavier Legette (Panthers)

Over 19.5

-114

Under 19.5

-114

Bucky Irving (Buccaneers)

Over 17.5

-114

Under 17.5

-114

Ja'Tavion Sanders (Panthers)

Over 14.5

-114

Under 14.5

-114

Rico Dowdle (Panthers)

Over 13.5

-114

Under 13.5

-114

Chuba Hubbard (Panthers)

Over 11.5

-114

Under 11.5

-114

Rushing Yards

Bucky Irving (Buccaneers)

Over 64.5

-114

Under 64.5

-114

Rico Dowdle (Panthers)

Over 58.5

-114

Under 58.5

-114

Chuba Hubbard (Panthers)

Over 31.5

-114

Under 31.5

-114

Sean Tucker (Buccaneers)

Over 13.5

-114

Under 13.5

-114

Bryce Young (Panthers)

Over 12.5

-114

Under 12.5

-114

Baker Mayfield (Buccaneers)

Over 12.5

-114

Under 12.5

-114

Passing Yards

Baker Mayfield (Buccaneers)

Over 228.5

-114

Under 228.5

-114

Bryce Young (Panthers)

Over 204.5

-114

Under 204.5

-114

Panthers Have Picked Up Five Wins in Past Ten at Home

The Panthers own a 5-5 mark in their past 10 home games, posting 23.40 points per contest while yielding 25.20.

The Bucs own a 6-4 mark in their past 10 games away from home, averaging 24.20 points scored and 24.50 points allowed.

The Bucs earned a 26-23 win against the Panthers in the teams’ last meeting at Bank of America Stadium. Over the previous 6 head-to-head clashes at Bank of America Stadium, the Bucs have collected five victories, while the Panthers have one.

Last 10 Games		W-L	P	PF	PA	O45.5	U45.5
Panthers Home Stats		5-5	48.60	23.40	25.20	7	3
Buccaneers Away Stats		6-4	48.70	24.20	24.50	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O45.5 = Games Over 45.5 Points
• U45.5 = Games Under 45.5 Points

Latest regular season and playoff games stats.

Tampa Bay Buccaneers Stats

Carolina Panthers Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• -3 Betting Line: Have covered the spread in 4 of the last 10 games
• -3 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +3 Betting Line: Have covered the spread in 7 of the last 10 games
• +3 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 48.70 pts in the previous 10 games
• Game Totals on the Road: An average of 48.70 pts in the previous 10 games on the road
• Over 45.5: Covered in 5 of the previous 10 games
• Over 45.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 23.00 pts and allowed 25.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 24.20 pts and allowed 24.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 41.10 pts in the previous 10 games
• Game Totals at Home: An average of 48.60 pts in the previous 10 home games
• Over 45.5: Covered in 5 of the previous 10 games
• Over 45.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 18.90 pts and allowed 22.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 23.40 pts and allowed 25.20 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 309.00 Yds. Allowed 378.40 Yds
• Rushing Yards: Gained 108.90 Yds. Allowed 107.90 Yds
• Passing Yards: Gained 200.10 Yds. Allowed 270.50 Yds
• Total Touchdowns: Scored 2.60 TD. Allowed 3.20 TD
• Rushing Touchdowns: Scored 1.10 TD. Allowed 1.30 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 19.20. Allowed 19.80
• Total Turnovers: Committed 0.90. Committed by opponents 1.80
• Total Penalties: Committed 4.50. Committed by opponents 7.90
• Penalty Yards: Lost 32.20 Yds. Gained 57.70 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 316.90 Yds. Allowed 333.10 Yds
• Rushing Yards: Gained 135.70 Yds. Allowed 110.70 Yds
• Passing Yards: Gained 181.20 Yds. Allowed 222.40 Yds
• Total Touchdowns: Scored 2.10 TD. Allowed 2.40 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 18.70. Allowed 19.70
• Total Turnovers: Committed 1.20. Committed by opponents 1.20
• Total Penalties: Committed 6.00. Committed by opponents 5.80
• Penalty Yards: Lost 46.40 Yds. Gained 42.20 Yds

Last 10 Games on the Road

• Total Yards: Gained 343.10 Yds. Allowed 337.80 Yds
• Rushing Yards: Gained 137.30 Yds. Allowed 79.50 Yds
• Passing Yards: Gained 205.80 Yds. Allowed 258.30 Yds
• Total Touchdowns: Scored 2.70 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 0.90 TD. Allowed 1.00 TD
• Passing Touchdowns: Scored 1.80 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 20.60. Allowed 18.30
• Total Turnovers: Committed 1.30. Committed by opponents 1.40
• Total Penalties: Committed 5.10. Committed by opponents 6.50
• Penalty Yards: Lost 42.60 Yds. Gained 47.50 Yds

Last 10 Home Games

• Total Yards: Gained 310.50 Yds. Allowed 367.40 Yds
• Rushing Yards: Gained 132.60 Yds. Allowed 150.10 Yds
• Passing Yards: Gained 177.90 Yds. Allowed 217.30 Yds
• Total Touchdowns: Scored 2.60 TD. Allowed 2.70 TD
• Rushing Touchdowns: Scored 1.00 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.30 TD. Allowed 1.80 TD
• Total 1st Downs: Picked up 19.30. Allowed 20.90
• Total Turnovers: Committed 1.40. Committed by opponents 1.20
• Total Penalties: Committed 6.50. Committed by opponents 7.20
• Penalty Yards: Lost 49.70 Yds. Gained 56.60 Yds

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