Tennessee Titans
American Football NFL State Farm Stadium Sun 5 Oct 16:05
Arizona Cardinals
  1. Prediction
  2. Bet Builder
  3. Odds
  4. Player Props
  5. Stats
  6. Team News
  7. Lineups
  8. Injuries
  9. Standings

NFL Betting Preview: Titans vs Cardinals

The Tennessee Titans go up against the Arizona Cardinals in this NFL Week 5 matchup at State Farm Stadium, with kickoff scheduled for 16:05 on Sunday 5 October. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Titans and Cardinals to Play Out High-Scoring Game

You can get -102 that there are Over 41.5 points and there’s lots of juice in those odds. The Cardinals and the Titans should be able to keep the score ticking for our prediction to win.

If you’re into our Totals play, don’t skip our comprehensive BetMGM review. And while you’re at it, grab the latest promo code.

Teams’ Last Battle Saw 38-13 Cardinals Victory

Tennessee Titans were beaten in their previous four games and the latest was on the road at NRG Stadium. Houston Texans claimed a 26-0 win. The Titans put up 175 total yards, made up of 93 through the air and 82 on the ground. They converted for 10 first downs and allowed 20.

Arizona Cardinals were defeated last time, making it back-to-back losses. State Farm Stadium saw them beaten 23-20 at home to Seattle Seahawks. The Cardinals finished with 253 yards, including 164 passing and 89 rushing yards. The offense converted for 18 first downs and scored 2 touchdowns, both through the air.

Head-to-Head Statistics

The scoreline was 38-13 in favor of the Cardinals when they last played the Titans, with the matchup taking place at Nissan Stadium.

Quarterbacks

Titans vs Cardinals Prediction & Picks

Our Titans vs Cardinals betting tips provide expert coverage of all major angles, including our main match prediction, top player prop picks, correct score recommendation and best bet builder insights.

Game Prediction

We’re predicting that the two teams will produce a significant combined points total in this NFL matchup. Therefore, our pick is to take the -102 that there are Over 41.5 points.

The NFL handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.

Key Titans vs Cardinals stats:

  • The 41.5 line has been covered in 7 of the last 10 Titans games on the road.
  • The 41.5 line has been covered in 11 of the last 20 Titans games.
  • The 41.5 line has been covered in the last 5 Cardinals games at home.
  • The 41.5 line has been covered in 7 of the last 10 Cardinals games.
  • The 41.5 line has been covered in 14 of the last 20 Cardinals games at home.

Over 41.5 Probability

According to the top sportsbooks, there’s a 50.5% likelihood of our pick landing a return. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 55-60%. This is why we can recommend this wager.

Looking for Bigger Odds?

There’s a chance to secure larger odds when you bet on the Totals. The sportsbooks allow you to move the line for an Over pick until you’re happy with the potential return.

Thinking about claiming free bets? Our bonus guide lists the best sign-up offers from the biggest names in betting.

Best Bet

Over 41.5 Points @ -102 Bet Now BetMGM logo
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Published 22:26, 03 October 2025

Player Prop Picks

Top Pick: Kyler Murray Over 219.5 Passing Yards -114 BetMGM logo

You can back Kyler Murray (Cardinals) at -114 to accumulate over 219.5 passing yards. We can back him in the QB Passing Yards market and hope the Over hits.

Latest Kyler Murray Player Prop Odds

Michael Carter Over 46.5 Rushing Yards -114 BetMGM logo

The odds for Michael Carter (Titans) to exceed 46.5 rushing yards stand at -114. We're confident in him covering the Player Rushing Yards line and hitting our Over bet.

Latest Michael Carter Player Prop Odds

Same Game Parlay Picks

Totals Over 41.5
Spread Cardinals -8.5
Passing Yards Kyler Murray Over 219.5

Take a same game parlay that incorporates Over 41.5 points followed by Cardinals to cover the -8.5 spread. We’ve also gone for Kyler Murray (Cardinals) to have Over 219.5 passing yards.

There are lots of options when you place a same game parlay. You can go through the football lines and identify your favorite picks before combining the odds on the bet slip. Personalised wagering doesn’t come any better.

T&C apply. Gamble responsibly 18+

Correct Score Prediction

Titans Titans logo 14 - 30 Cardinals logo Cardinals

Correct score betting might be tough to predict but there’s a huge potential return if you get it right. We’ll try the Cardinals to achieve a 30-14 victory at monster odds.

Titans vs Cardinals Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Make Cardinals Big Favorites

According to the Moneyline betting odds, Arizona Cardinals are red-hot -455 favorites with the sportsbooks and that means a 82% chance of winning this game. At +350, Tennessee Titans are regarded as having a lower probability of winning.

There is a spread of 8.5 and total points has a line of 41.5. There are many ways to bet on the NFL including the Totals. If you want to back Over 41.5, it’s -102.

Consider every angle when placing your National Football League wagers. The top betting apps have a huge selection of game lines and team props and it’s all about finding a bet which matches your prediction of the game.

Michael Carter Favorite to Score First Touchdown

Favorite Michael Carter is now available at +600 to be the First Touchdown Scorer. You will find similar odds apply when it comes to him scoring the last TD.

Touchdown

Michael Carter (Cardinals)
First TD
+600
Anytime TD
+110
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Trey McBride (Cardinals)
First TD
+600
Anytime TD
+130
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Tyjae Spears (Titans)
First TD
+650
Anytime TD
+110
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Tony Pollard (Titans)
First TD
+650
Anytime TD
+110
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Receiving Yards

Trey McBride (Cardinals)
Over 63.5
-114
Under 63.5
-114
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Marvin Harrison Jr. (Cardinals)
Over 54.5
-114
Under 54.5
-114
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Elic Ayomanor (Titans)
Over 40.5
-114
Under 40.5
-114
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Calvin Ridley (Titans)
Over 39.5
-114
Under 39.5
-114
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Rushing Yards

Tony Pollard (Titans)
Over 64.5
-114
Under 64.5
-114
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Michael Carter (Cardinals)
Over 46.5
-114
Under 46.5
-114
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Kyler Murray (Cardinals)
Over 29.5
-114
Under 29.5
-114
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Emari Demercado (Cardinals)
Over 19.5
-114
Under 19.5
-114
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Passing Yards

Best Betting Offers
State Farm Stadium
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Cardinals Own Six Wins From Last Ten at Home

The Cardinals own a 6-4 mark in their past 10 home games, averaging 24.60 points on offense and surrendering 20.80 on defense.

The Titans have dropped five road games in a row. They have two wins and eight losses in the last 10 games on the road, averaging 17.80 points scored and 29.80 points allowed.

Last 10 Games W-L P PF PA O41.5 U41.5
Cardinals logo Cardinals Home Stats 6-4 45.40 24.60 20.80 6 4
Titans logo Titans Away Stats 2-8 47.60 17.80 29.80 7 3
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O41.5 = Games Over 41.5 Points
  • U41.5 = Games Under 41.5 Points
Team Stats

Latest regular season and playoff games stats.

Tennessee Titans logo Tennessee Titans Stats
Arizona Cardinals logo Arizona Cardinals Stats
Moneyline
  • 0 wins and 10 defeats in the last 10 games
  • 2 wins and 8 defeats in the last 10 games on the road
Moneyline
  • 4 wins and 6 defeats in the last 10 games
  • 6 wins and 4 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points
Game Stats
Last 10 Games
Game Stats
Last 10 Games
Last 10 Games on the Road
Last 10 Home Games

Team News

Tennessee Titans Injuries

Type
Name
Info
Mike Brown
Knee
Treylon Burks
Collarbone
Blake Hance
Shoulder
JC Latham
Hip
Will Levis
Shoulder
James Lynch
Shoulder
Kalel Mullings
Ankle
Bryce Oliver
Knee
Anfernee Orji
Knee - ACL
Calvin Ridley
Knee
Tyjae Spears
Ankle
T'Vondre Sweat
Ankle
Kevin Winston
Hamstring

Arizona Cardinals Injuries

Type
Name
Info
Trey Benson
Knee - Meniscus
Joey Blount
Neck
Evan Brown
Hamstring
Denzel Burke
Knee
L.J. Collier
Knee
Hayden Conner
Knee
James Conner
Foot
Greg Dortch
Collarbone
Will Hernandez
Knee - ACL
Will Johnson
Groin
Christian Jones
Knee
Justin Jones
Knee
Sean Murphy-Bunting
Knee
Bilal Nichols
Neck
Walter Nolen
Calf
BJ Ojulari
Knee - ACL
Darius Robinson
Pectoral
J.J. Russell
Concussion
Valentin Senn
Undisclosed
Starling Thomas
Knee - ACL
Garrett Williams
Knee

Previous Tennessee Titans Lineups

28 Sep NFL
Titans 0-26 Texans
21 Sep NFL
Colts 41-20 Titans
14 Sep NFL
Rams 33-19 Titans
07 Sep NFL
Titans 12-20 Broncos
05 Jan NFL
Texans 23-14 Titans
29 Dec NFL
Titans 13-20 Jaguars
22 Dec NFL
Titans 30-38 Colts
15 Dec NFL
Bengals 37-27 Titans
08 Dec NFL
Jaguars 10-6 Titans
01 Dec NFL
Titans 19-42 Commanders

Previous Arizona Cardinals Lineups

25 Sep NFL
Seahawks 23-20 Cardinals
21 Sep NFL
Cardinals 15-16 49ers
14 Sep NFL
Panthers 22-27 Cardinals
07 Sep NFL
Cardinals 20-13 Saints
05 Jan NFL
49ers 24-47 Cardinals
28 Dec NFL
Cardinals 9-13 Rams
22 Dec NFL
Cardinals 30-36 Panthers
15 Dec NFL
Patriots 17-30 Cardinals
08 Dec NFL
Seahawks 30-18 Cardinals
01 Dec NFL
Cardinals 22-23 Vikings

NFL Standings Select Season

AFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 4 0 0 1.000 133 90 43 3-0-0 1-0-0 2-0-0 3-0-0 4-0-0 4W
Patriots 2 2 0 0.500 102 81 21 1-2-0 1-0-0 1-0-0 1-2-0 2-2-0 1W
Dolphins 1 3 0 0.250 83 118 -35 1-1-0 0-2-0 1-2-0 1-3-0 1-3-0 1W
Jets 0 4 0 0.000 90 120 -30 0-2-0 0-2-0 0-2-0 0-3-0 0-4-0 4L
AFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Steelers 3 1 0 0.750 96 98 -2 1-1-0 2-0-0 0-0-0 2-0-0 3-1-0 2W
Bengals 2 2 0 0.500 61 119 -58 1-0-0 1-2-0 1-0-0 2-1-0 2-2-0 2L
Ravens 1 3 0 0.250 131 133 -2 1-1-0 0-2-0 1-0-0 1-2-0 1-3-0 2L
Browns 1 3 0 0.250 56 102 -46 1-1-0 0-2-0 0-2-0 0-2-0 1-3-0 1L
AFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Colts 3 1 0 0.750 123 83 40 2-0-0 1-1-0 1-0-0 3-0-0 3-1-0 1L
Jaguars 3 1 0 0.750 96 72 24 2-0-0 1-1-0 1-0-0 1-1-0 3-1-0 2W
Texans 1 3 0 0.250 64 51 13 1-1-0 0-2-0 1-1-0 1-1-0 1-3-0 1W
Titans 0 4 0 0.000 51 120 -69 0-2-0 0-2-0 0-2-0 0-3-0 0-4-0 4L
AFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Chargers 3 1 0 0.750 88 71 17 2-0-0 1-1-0 3-0-0 3-0-0 3-1-0 1L
Chiefs 2 2 0 0.500 97 76 21 1-1-0 1-1-0 0-1-0 1-1-0 2-2-0 2W
Broncos 2 2 0 0.500 96 67 29 2-0-0 0-2-0 0-1-0 2-2-0 2-2-0 1W
Raiders 1 3 0 0.250 77 99 -22 0-2-0 1-1-0 0-1-0 1-1-0 1-3-0 3L
NFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Eagles 4 0 0 1.000 108 88 20 2-0-0 2-0-0 1-0-0 3-0-0 4-0-0 4W
Commanders 2 2 0 0.500 107 91 16 2-0-0 0-2-0 1-0-0 1-2-0 2-2-0 1L
Cowboys 1 2 1 0.250 114 132 -18 1-0-1 0-2-0 1-1-0 1-2-1 1-2-1 1D
Giants 1 3 0 0.250 73 101 -28 1-1-0 0-2-0 0-2-0 0-2-0 1-3-0 1W
NFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Lions 3 1 0 0.750 137 88 49 2-0-0 1-1-0 1-1-0 1-1-0 3-1-0 3W
Packers 2 1 1 0.500 104 84 20 2-0-0 0-1-1 1-0-0 2-0-1 2-1-1 1D
Vikings 2 2 0 0.500 102 80 22 1-1-0 1-1-0 1-0-0 1-1-0 2-2-0 1L
Bears 2 2 0 0.500 101 117 -16 1-1-0 1-1-0 0-2-0 1-2-0 2-2-0 2W
NFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Buccaneers 3 1 0 0.750 97 97 0 1-1-0 2-0-0 1-0-0 1-1-0 3-1-0 1L
Falcons 2 2 0 0.500 76 86 -10 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 1W
Panthers 1 3 0 0.250 75 95 -20 1-0-0 0-3-0 1-0-0 1-1-0 1-3-0 1L
Saints 0 4 0 0.000 66 121 -55 0-2-0 0-2-0 0-0-0 0-3-0 0-4-0 4L
NFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
49ers 4 1 0 0.800 106 98 8 1-1-0 3-0-0 3-0-0 4-0-0 4-1-0 1W
Seahawks 3 1 0 0.750 111 67 44 1-1-0 2-0-0 1-1-0 2-1-0 3-1-0 3W
Rams 3 2 0 0.600 123 107 16 2-1-0 1-1-0 0-1-0 0-2-0 3-2-0 1L
Cardinals 2 2 0 0.500 82 74 8 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 2L
AFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 4 0 0 1.000 133 90 43 3-0-0 1-0-0 2-0-0 3-0-0 4-0-0 4W
Chargers 3 1 0 0.750 88 71 17 2-0-0 1-1-0 3-0-0 3-0-0 3-1-0 1L
Steelers 3 1 0 0.750 96 98 -2 1-1-0 2-0-0 0-0-0 2-0-0 3-1-0 2W
Colts 3 1 0 0.750 123 83 40 2-0-0 1-1-0 1-0-0 3-0-0 3-1-0 1L
Jaguars 3 1 0 0.750 96 72 24 2-0-0 1-1-0 1-0-0 1-1-0 3-1-0 2W
Bengals 2 2 0 0.500 61 119 -58 1-0-0 1-2-0 1-0-0 2-1-0 2-2-0 2L
Chiefs 2 2 0 0.500 97 76 21 1-1-0 1-1-0 0-1-0 1-1-0 2-2-0 2W
Broncos 2 2 0 0.500 96 67 29 2-0-0 0-2-0 0-1-0 2-2-0 2-2-0 1W
Patriots 2 2 0 0.500 102 81 21 1-2-0 1-0-0 1-0-0 1-2-0 2-2-0 1W
Raiders 1 3 0 0.250 77 99 -22 0-2-0 1-1-0 0-1-0 1-1-0 1-3-0 3L
Texans 1 3 0 0.250 64 51 13 1-1-0 0-2-0 1-1-0 1-1-0 1-3-0 1W
Ravens 1 3 0 0.250 131 133 -2 1-1-0 0-2-0 1-0-0 1-2-0 1-3-0 2L
Dolphins 1 3 0 0.250 83 118 -35 1-1-0 0-2-0 1-2-0 1-3-0 1-3-0 1W
Browns 1 3 0 0.250 56 102 -46 1-1-0 0-2-0 0-2-0 0-2-0 1-3-0 1L
Jets 0 4 0 0.000 90 120 -30 0-2-0 0-2-0 0-2-0 0-3-0 0-4-0 4L
Titans 0 4 0 0.000 51 120 -69 0-2-0 0-2-0 0-2-0 0-3-0 0-4-0 4L
NFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Eagles 4 0 0 1.000 108 88 20 2-0-0 2-0-0 1-0-0 3-0-0 4-0-0 4W
49ers 4 1 0 0.800 106 98 8 1-1-0 3-0-0 3-0-0 4-0-0 4-1-0 1W
Lions 3 1 0 0.750 137 88 49 2-0-0 1-1-0 1-1-0 1-1-0 3-1-0 3W
Buccaneers 3 1 0 0.750 97 97 0 1-1-0 2-0-0 1-0-0 1-1-0 3-1-0 1L
Seahawks 3 1 0 0.750 111 67 44 1-1-0 2-0-0 1-1-0 2-1-0 3-1-0 3W
Rams 3 2 0 0.600 123 107 16 2-1-0 1-1-0 0-1-0 0-2-0 3-2-0 1L
Packers 2 1 1 0.500 104 84 20 2-0-0 0-1-1 1-0-0 2-0-1 2-1-1 1D
Falcons 2 2 0 0.500 76 86 -10 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 1W
Vikings 2 2 0 0.500 102 80 22 1-1-0 1-1-0 1-0-0 1-1-0 2-2-0 1L
Cardinals 2 2 0 0.500 82 74 8 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 2L
Bears 2 2 0 0.500 101 117 -16 1-1-0 1-1-0 0-2-0 1-2-0 2-2-0 2W
Commanders 2 2 0 0.500 107 91 16 2-0-0 0-2-0 1-0-0 1-2-0 2-2-0 1L
Cowboys 1 2 1 0.250 114 132 -18 1-0-1 0-2-0 1-1-0 1-2-1 1-2-1 1D
Panthers 1 3 0 0.250 75 95 -20 1-0-0 0-3-0 1-0-0 1-1-0 1-3-0 1L
Giants 1 3 0 0.250 73 101 -28 1-1-0 0-2-0 0-2-0 0-2-0 1-3-0 1W
Saints 0 4 0 0.000 66 121 -55 0-2-0 0-2-0 0-0-0 0-3-0 0-4-0 4L
NFL Team W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 4 0 0 1.000 133 90 43 3-0-0 1-0-0 2-0-0 3-0-0 4-0-0 4W
Eagles 4 0 0 1.000 108 88 20 2-0-0 2-0-0 1-0-0 3-0-0 4-0-0 4W
49ers 4 1 0 0.800 106 98 8 1-1-0 3-0-0 3-0-0 4-0-0 4-1-0 1W
Lions 3 1 0 0.750 137 88 49 2-0-0 1-1-0 1-1-0 1-1-0 3-1-0 3W
Colts 3 1 0 0.750 123 83 40 2-0-0 1-1-0 1-0-0 3-0-0 3-1-0 1L
Jaguars 3 1 0 0.750 96 72 24 2-0-0 1-1-0 1-0-0 1-1-0 3-1-0 2W
Chargers 3 1 0 0.750 88 71 17 2-0-0 1-1-0 3-0-0 3-0-0 3-1-0 1L
Steelers 3 1 0 0.750 96 98 -2 1-1-0 2-0-0 0-0-0 2-0-0 3-1-0 2W
Seahawks 3 1 0 0.750 111 67 44 1-1-0 2-0-0 1-1-0 2-1-0 3-1-0 3W
Buccaneers 3 1 0 0.750 97 97 0 1-1-0 2-0-0 1-0-0 1-1-0 3-1-0 1L
Packers 2 1 1 0.500 104 84 20 2-0-0 0-1-1 1-0-0 2-0-1 2-1-1 1D
Rams 3 2 0 0.600 123 107 16 2-1-0 1-1-0 0-1-0 0-2-0 3-2-0 1L
Cardinals 2 2 0 0.500 82 74 8 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 2L
Falcons 2 2 0 0.500 76 86 -10 1-1-0 1-1-0 0-2-0 2-2-0 2-2-0 1W
Bears 2 2 0 0.500 101 117 -16 1-1-0 1-1-0 0-2-0 1-2-0 2-2-0 2W
Bengals 2 2 0 0.500 61 119 -58 1-0-0 1-2-0 1-0-0 2-1-0 2-2-0 2L
Broncos 2 2 0 0.500 96 67 29 2-0-0 0-2-0 0-1-0 2-2-0 2-2-0 1W
Chiefs 2 2 0 0.500 97 76 21 1-1-0 1-1-0 0-1-0 1-1-0 2-2-0 2W
Vikings 2 2 0 0.500 102 80 22 1-1-0 1-1-0 1-0-0 1-1-0 2-2-0 1L
Patriots 2 2 0 0.500 102 81 21 1-2-0 1-0-0 1-0-0 1-2-0 2-2-0 1W
Commanders 2 2 0 0.500 107 91 16 2-0-0 0-2-0 1-0-0 1-2-0 2-2-0 1L
Cowboys 1 2 1 0.250 114 132 -18 1-0-1 0-2-0 1-1-0 1-2-1 1-2-1 1D
Ravens 1 3 0 0.250 131 133 -2 1-1-0 0-2-0 1-0-0 1-2-0 1-3-0 2L
Panthers 1 3 0 0.250 75 95 -20 1-0-0 0-3-0 1-0-0 1-1-0 1-3-0 1L
Browns 1 3 0 0.250 56 102 -46 1-1-0 0-2-0 0-2-0 0-2-0 1-3-0 1L
Texans 1 3 0 0.250 64 51 13 1-1-0 0-2-0 1-1-0 1-1-0 1-3-0 1W
Raiders 1 3 0 0.250 77 99 -22 0-2-0 1-1-0 0-1-0 1-1-0 1-3-0 3L
Dolphins 1 3 0 0.250 83 118 -35 1-1-0 0-2-0 1-2-0 1-3-0 1-3-0 1W
Giants 1 3 0 0.250 73 101 -28 1-1-0 0-2-0 0-2-0 0-2-0 1-3-0 1W
Saints 0 4 0 0.000 66 121 -55 0-2-0 0-2-0 0-0-0 0-3-0 0-4-0 4L
Jets 0 4 0 0.000 90 120 -30 0-2-0 0-2-0 0-2-0 0-3-0 0-4-0 4L
Titans 0 4 0 0.000 51 120 -69 0-2-0 0-2-0 0-2-0 0-3-0 0-4-0 4L