Titans vs Broncos Prediction, Picks & Odds | 07 Sep 2025

NFL Betting Preview: Titans vs Broncos

The Tennessee Titans meet the Denver Broncos in this NFL Week 1 matchup at Empower Field at Mile High, with kickoff scheduled for 16:05 on Sunday, September 7. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Over 42.5 points seems like a realistic outcome when the Broncos go up against the Titans. We’re taking odds of -104 on the basis that the total line is too low.

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Tennessee Titans were beaten 23-14 at Nissan Stadium in their previous game, being turned over at home to Houston Texans. The Titans finished with 314 yards, including 229 passing and 85 rushing yards. The offense moved the chains 14 times and reached the end zone once through the air.

Denver Broncos lost their last game in the Wild Card Round of the playoffs, falling 31–7 on the road to the Buffalo Bills at Highmark Stadium. The Broncos totaled 224 yards with 145 passing and 79 rushing, while picking up 13 first downs and scoring one touchdown.

Head-to-Head Statistics

The Titans have beaten the Broncos in the last two meetings. They won 16-14 at Empower Field at Mile High and triumphed 17-10 at Nissan Stadium. The previous 3 games featuring these teams have resulted in two Titans victories.

Quarterbacks

Cam Ward

188.5 Passing Yards

Over -112

Under -112

Bo Nix

214.5 Passing Yards

Over -112

Under -112

Titans vs Broncos Prediction & Picks

Be fully equipped for Titans vs Broncos with our betting guide, offering a key match prediction, a correct score recommendation, top player prop picks and a bet builder tailored for value.

Game Prediction

There are odds of -104 about Over 42.5 points and this looks generous for this NFL matchup. The bar might have been set too low in terms of total.

The NFL handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.

Key Titans vs Broncos stats:

• The 42.5 line has been covered in 4 of the last 5 Titans games on the road.
• The 42.5 line has been covered in 7 of the last 10 Titans games on the road.
• The 42.5 line has been covered in 7 of the last 10 Broncos games.
• The 42.5 line has been covered in 3 of the last 5 Broncos games.

Over 42.5 Probability

The best sportsbooks are estimating that there is a 51% likelihood of this pick winning. After careful examination, our experts calculate this probability to be somewhere between 55-60%. That means we’re regarding it as a value bet.

If you want to go Over on the Totals at bigger odds, then you can combine this pick with other selections in a Bet Builder until you’re happy with the potential return.

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Our Game Prediction

Over 42.5 Points @ -104 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (22:26, 05 September 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Bo Nix Over 210.5 Passing Yards -114

You can place a bet on Bo Nix (Broncos) at -114 to go over 210.5 passing yards. The line for QB Passing Yards looks attractive and we’re confident of securing a return.

Latest Bo Nix Player Prop Odds

Touchdown

Anytime

+260

First

+1200

Passing Yards

Over 214.5

-112

Under 214.5

-112

Rushing Yards

Over 18.5

-112

Under 18.5

-112

---

Calvin Ridley Over 53.5 Receiving Yards -114

The odds for Calvin Ridley (Titans) to rack up over 53.5 receiving yards stand at -114. The line for him on the Overs is highly appealing, with Player Receiving Yards bettors able to get plenty of juice.

Latest Calvin Ridley Player Prop Odds

Touchdown

Anytime

+280

First

+1600

Receiving Yards

Over 51.5

-112

Under 51.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Titans 14 - 31 Broncos

The Broncos to win by a 31-14 scoreline could be worth a chance. There’s a massive potential return if you can land this bet on the money and it should provide some entertainment.

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Titans vs Broncos Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The latest Moneyline betting odds give Denver Broncos a 83% chance of winning this game which means they’re overwhelming -500 favorites with the sportsbooks. Tennessee Titans are regarded as a long shot to win and you can currently back them at +385.

The spread is calculated to be 8.5, while total points comes in at 42.5. NFL bettors love the chance to get an alternative angle by going for a Total wager. If you're keen on Over 42.5, this selection is available at -110.

The best NFL sportsbooks offer a wide range of team props and game lines for every matchup. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Titans

+385

Broncos

-500

Point Spread

Titans +8.5

-105

Broncos -8.5

-115

Total Points

Under 42.5

-110

Over 42.5

-110

Courtland Sutton is the First Touchdown Scorer favorite at +600. Alternatively, there’s the chance to simply back him to score a TD anytime at +125.

Touchdown

Courtland Sutton (Broncos)

First TD

+600

Anytime TD

+125

Tony Pollard (Titans)

First TD

+650

Anytime TD

+105

J.K. Dobbins (Broncos)

First TD

+700

Anytime TD

+140

RJ Harvey (Broncos)

First TD

+750

Anytime TD

+140

Evan Engram (Broncos)

First TD

+900

Anytime TD

+200

Marvin Mims Jr. (Broncos)

First TD

+1100

Anytime TD

+240

Bo Nix (Broncos)

First TD

+1200

Anytime TD

+260

Calvin Ridley (Titans)

First TD

+1600

Anytime TD

+280

Troy Franklin (Broncos)

First TD

+2000

Anytime TD

+500

Chigoziem Okonkwo (Titans)

First TD

+2700

Anytime TD

+550

Cam Ward (Titans)

First TD

+3000

Anytime TD

+600

Adam Trautman (Broncos)

First TD

+3500

Anytime TD

+900

Elic Ayomanor (Titans)

First TD

+3500

Anytime TD

+750

Tyler Lockett (Titans)

First TD

+3500

Anytime TD

+700

Jaleel McLaughlin (Broncos)

First TD

+3500

Anytime TD

+870

Trent Sherfield Sr. (Broncos)

First TD

+4000

Anytime TD

+1100

Nate Adkins (Broncos)

First TD

+4000

Anytime TD

+1000

Kalel Mullings (Titans)

First TD

+4500

Anytime TD

+850

Pat Bryant (Broncos)

First TD

+4500

Anytime TD

+1100

Lucas Krull (Broncos)

First TD

+5000

Anytime TD

+1300

Julius Chestnut (Titans)

First TD

+5500

Anytime TD

+1100

Tyler Badie (Broncos)

First TD

+5500

Anytime TD

+1300

Van Jefferson (Titans)

First TD

+7500

Anytime TD

+1300

Michael Burton (Broncos)

First TD

+8000

Anytime TD

+1900

Gunnar Helm (Titans)

First TD

+8000

Anytime TD

+1700

Adam Prentice (Broncos)

First TD

+8000

Anytime TD

+2200

Chimere Dike (Titans)

First TD

+10000

Anytime TD

+2500

David Martin-Robinson (Titans)

First TD

+10000

Anytime TD

+3000

Bryce Oliver (Titans)

First TD

+10000

Anytime TD

+3500

Receiving Yards

Courtland Sutton (Broncos)

Over 58.5

-112

Under 58.5

-112

Calvin Ridley (Titans)

Over 51.5

-112

Under 51.5

-112

Marvin Mims Jr. (Broncos)

Over 36.5

-112

Under 36.5

-112

Evan Engram (Broncos)

Over 34.5

-112

Under 34.5

-112

Chigoziem Okonkwo (Titans)

Over 32.5

-112

Under 32.5

-112

Elic Ayomanor (Titans)

Over 21.5

-112

Under 21.5

-112

Tyler Lockett (Titans)

Over 21.5

-112

Under 21.5

-112

Troy Franklin (Broncos)

Over 18.5

-112

Under 18.5

-112

Tony Pollard (Titans)

Over 14.5

-112

Under 14.5

-112

RJ Harvey (Broncos)

Over 12.5

-112

Under 12.5

-112

J.K. Dobbins (Broncos)

Over 9.5

-112

Under 9.5

-112

Rushing Yards

Tony Pollard (Titans)

Over 61.5

-112

Under 61.5

-112

RJ Harvey (Broncos)

Over 40.5

-112

Under 40.5

-112

J.K. Dobbins (Broncos)

Over 37.5

-112

Under 37.5

-112

Bo Nix (Broncos)

Over 18.5

-112

Under 18.5

-112

Cam Ward (Titans)

Over 13.5

-112

Under 13.5

-112

Passing Yards

Bo Nix (Broncos)

Over 214.5

-112

Under 214.5

-112

Cam Ward (Titans)

Over 188.5

-112

Under 188.5

-112

Instead of focusing on the overall outcome, some bettors prefer to look at the NFL micro betting lines. As the name suggests, it means placing short-term wagers and this might include the Next Play or Next Drive Result.

Broncos Building a Fortress at Home

The Broncos are riding five straight wins at Empower Field at Mile High. They own a 7-3 mark in their past 10 home games, posting 27.10 points per contest while yielding 15.40.

The Titans have taken three straight defeats on the road. They own a 2-8 mark in their past 10 games on the road, putting up 18.60 points on average and giving up 30.20.

When the teams last met at Empower Field at Mile High, the Titans beat the Broncos 16-14.

Last 10 Games		W-L	P	PF	PA	O42.5	U42.5
Broncos Home Stats		7-3	42.50	27.10	15.40	5	5
Titans Away Stats		2-8	48.80	18.60	30.20	7	3

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O42.5 = Games Over 42.5 Points
• U42.5 = Games Under 42.5 Points

Latest regular season and playoff games stats.

Tennessee Titans Stats

Denver Broncos Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +8.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +8.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -8.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -8.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 45.50 pts in the previous 10 games
• Game Totals on the Road: An average of 48.80 pts in the previous 10 games on the road
• Over 42.5: Covered in 5 of the previous 10 games
• Over 42.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 19.10 pts and allowed 26.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 18.60 pts and allowed 30.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 48.10 pts in the previous 10 games
• Game Totals at Home: An average of 42.50 pts in the previous 10 home games
• Over 42.5: Covered in 7 of the previous 10 games
• Over 42.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 25.90 pts and allowed 22.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 27.10 pts and allowed 15.40 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 320.10 Yds. Allowed 343.20 Yds
• Rushing Yards: Gained 101.70 Yds. Allowed 147.90 Yds
• Passing Yards: Gained 218.40 Yds. Allowed 195.30 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 3.30 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 1.40 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 18.20. Allowed 20.30
• Total Turnovers: Committed 1.80. Committed by opponents 1.50
• Total Penalties: Committed 8.20. Committed by opponents 7.30
• Penalty Yards: Lost 62.60 Yds. Gained 58.10 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 328.40 Yds. Allowed 360.10 Yds
• Rushing Yards: Gained 101.60 Yds. Allowed 99.80 Yds
• Passing Yards: Gained 226.80 Yds. Allowed 260.30 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.30 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.60 TD
• Passing Touchdowns: Scored 2.30 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 19.20. Allowed 21.20
• Total Turnovers: Committed 0.70. Committed by opponents 1.30
• Total Penalties: Committed 5.70. Committed by opponents 4.70
• Penalty Yards: Lost 48.80 Yds. Gained 35.70 Yds

Last 10 Games on the Road

• Total Yards: Gained 292.10 Yds. Allowed 304.30 Yds
• Rushing Yards: Gained 109.90 Yds. Allowed 144.80 Yds
• Passing Yards: Gained 182.20 Yds. Allowed 159.50 Yds
• Total Touchdowns: Scored 1.90 TD. Allowed 3.50 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 1.40 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 17.50. Allowed 18.00
• Total Turnovers: Committed 2.00. Committed by opponents 0.60
• Total Penalties: Committed 7.10. Committed by opponents 6.30
• Penalty Yards: Lost 51.10 Yds. Gained 51.60 Yds

Last 10 Home Games

• Total Yards: Gained 336.10 Yds. Allowed 299.10 Yds
• Rushing Yards: Gained 101.00 Yds. Allowed 90.10 Yds
• Passing Yards: Gained 235.10 Yds. Allowed 209.00 Yds
• Total Touchdowns: Scored 3.30 TD. Allowed 1.60 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 0.30 TD
• Passing Touchdowns: Scored 2.20 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 18.90. Allowed 16.70
• Total Turnovers: Committed 1.30. Committed by opponents 1.60
• Total Penalties: Committed 5.70. Committed by opponents 6.00
• Penalty Yards: Lost 52.30 Yds. Gained 48.10 Yds

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