Titans vs Texans Prediction, Picks & Odds | 28 Sep 2025

NFL Betting Preview: Titans vs Texans

The Tennessee Titans face the Houston Texans in this NFL Week 4 matchup at NRG Stadium, with kickoff scheduled for 13:00 on Sunday, September 28. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

There’s juice available when it comes to backing Over 38.5 points between the Texans and the Titans. Our prediction is priced up at -115 which looks worth taking.

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Tennessee Titans have suffered three straight defeats, recently being beaten at home by Indianapolis Colts 41-20 at Nissan Stadium. The Titans recorded 282 yards, with 196 through the air and 86 on the ground. The offense scored two touchdowns and managed 21 first downs.

Houston Texans have been defeated in their last three games. On the road, they recently suffered a 17-10 loss against Jacksonville Jaguars at EverBank Stadium. The Texans totaled 271 yards, with 184 through the air and 87 on the ground. The offense picked up 13 first downs along with a single touchdown.

Head-to-Head Statistics

The Texans won the last matchup between the pair. Enjoying a 23-14 triumph when facing the Titans at Nissan Stadium. The past 10 games H2H record shows that both teams have five wins.

Quarterbacks

Cam Ward

187.5 Passing Yards

Over -112

Under -112

C.J. Stroud

216.5 Passing Yards

Over -112

Under -112

Titans vs Texans Prediction & Picks

From our key match prediction to correct score pick, top player prop insights and a builder tailored for value — our Titans vs Texans betting tips covers it all.

Game Prediction

The best betting angle could be wagering on the totals for this NFL matchup. Our pick is for Over 38.5 points to be scored at odds of -115 which makes lots of appeal.

Injuries are always factored in by the NFL handicappers at Sportsgambler.com. Our picks are also shaped by recent form, with up-to-date stats playing a key role before any selections are locked in.

Key Titans vs Texans stats:

• The 38.5 line has been covered in 8 of the last 10 Titans games on the road.
• The 38.5 line has been covered in 13 of the last 20 Titans games.
• The 38.5 line has been covered in the last 2 Titans games.
• The 38.5 line has been covered in 7 of the last 10 Texans games at home.
• The 38.5 line has been covered in 13 of the last 20 Texans games.
• The 38.5 line has been covered in the last 2 Texans games at home.

Over 38.5 Probability

According to the top sportsbooks, our pick has a 53.5% chance of delivering a return. However, our analysts research has found that the actual probability is closer to 60%. It’s why we think it’s worth placing this bet.

There’s a chance to secure larger odds when you bet on the Totals. The sportsbooks allow you to move the line for an Over pick until you’re happy with the potential return.

Claim bonuses and free bets before placing a wager. Our in-depth guide shows you the best current betting offers.

Our Game Prediction

Over 38.5 Points @ -115 Bet Now

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Player Prop Picks

Top Pick: C.J. Stroud Over 223.5 Passing Yards -114

C.J. Stroud (Texans) can be backed at -114 to accumulate over 223.5 passing yards. We’re happy to take him to cover the QB Passing Yards line and bettors can place this wager with confidence.

Latest C.J. Stroud Player Prop Odds

Touchdown

Anytime

+550

First

+2000

Passing Yards

Over 216.5

-112

Under 216.5

-112

Rushing Yards

Over 14.5

-112

Under 14.5

-112

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Christian Kirk Over 39.5 Receiving Yards -114

You can place a bet on Christian Kirk (Titans) at -114 to accumulate over 39.5 receiving yards. We’re tempted to back him to cover the Player Receiving Yards line, with plenty of juice on offer.

Latest Christian Kirk Player Prop Odds

Touchdown

Anytime

+330

First

+1200

Receiving Yards

Over 39.5

-112

Under 39.5

-112

Correct Score Prediction

Titans 13 - 28 Texans

You don’t need a big stake to enjoy a monster return by getting this correct score right. We’re going for the Texans to claim a 28-13 victory and hopefully this goes close.

Titans vs Texans Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Houston Texans are -370 favorites and that means a 79% chance of winning this game according to the Moneyline betting odds with the sportsbooks. For those wanting to back Tennessee Titans, you will find +300 about the underdogs.

The spread currently stands at 7.5 and the total points line is 39.5. A Total wager relates to the number of points that will be scored overall. The Over 39.5 selection is available to back at -105.

The good news is that you can access a wide range of game lines and team props for every National Football League matchup. The best betting apps offer a great selection of pre-game and in-game wagering options.

Moneyline

Titans

+300

Texans

-370

Point Spread

Titans +7.5

-122

Texans -7.5

-100

Total Points

Under 39.5

-115

Over 39.5

-105

Nico Collins is the market leader to be First TD Scorer at +500. Alternatively, there’s the chance to back him to register a touchdown at any stage at +110.

Touchdown

Nico Collins (Texans)

First TD

+500

Anytime TD

+110

Tony Pollard (Titans)

First TD

+600

Anytime TD

+120

Nick Chubb (Texans)

First TD

+600

Anytime TD

+130

Woody Marks (Texans)

First TD

+900

Anytime TD

+210

Dalton Schultz (Texans)

First TD

+1100

Anytime TD

+290

Christian Kirk (Texans)

First TD

+1200

Anytime TD

+330

Calvin Ridley (Titans)

First TD

+1500

Anytime TD

+340

Elic Ayomanor (Titans)

First TD

+1900

Anytime TD

+450

C.J. Stroud (Texans)

First TD

+2000

Anytime TD

+550

Xavier Hutchinson (Texans)

First TD

+2200

Anytime TD

+550

Jayden Higgins (Texans)

First TD

+2500

Anytime TD

+600

Cam Ward (Titans)

First TD

+2700

Anytime TD

+650

Chigoziem Okonkwo (Titans)

First TD

+2700

Anytime TD

+700

Chimere Dike (Titans)

First TD

+3000

Anytime TD

+650

Jaylin Noel (Texans)

First TD

+3500

Anytime TD

+1000

Julius Chestnut (Titans)

First TD

+4500

Anytime TD

+1000

Harrison Bryant (Texans)

First TD

+5000

Anytime TD

+1300

Tyler Lockett (Titans)

First TD

+5000

Anytime TD

+1500

Braxton Berrios (Texans)

First TD

+5000

Anytime TD

+1300

Gunnar Helm (Titans)

First TD

+6500

Anytime TD

+1500

Dare Ogunbowale (Texans)

First TD

+8000

Anytime TD

+1900

British Brooks (Texans)

First TD

+8000

Anytime TD

+1900

Van Jefferson (Titans)

First TD

+10000

Anytime TD

+2200

David Martin-Robinson (Titans)

First TD

+10000

Anytime TD

+5500

Jordan Mims (Titans)

First TD

+10000

Anytime TD

+3300

Receiving Yards

Nico Collins (Texans)

Over 70.5

-112

Under 70.5

-112

Calvin Ridley (Titans)

Over 45.5

-112

Under 45.5

-112

Christian Kirk (Texans)

Over 39.5

-112

Under 39.5

-112

Chigoziem Okonkwo (Titans)

Over 32.5

-112

Under 32.5

-112

Dalton Schultz (Texans)

Over 29.5

-112

Under 29.5

-112

Elic Ayomanor (Titans)

Over 28.5

-112

Under 28.5

-112

Xavier Hutchinson (Texans)

Over 15.5

-112

Under 15.5

-112

Tyler Lockett (Titans)

Over 13.5

-112

Under 13.5

-112

Tony Pollard (Titans)

Over 10.5

-112

Under 10.5

-112

Woody Marks (Texans)

Over 8.5

-102

Under 8.5

-123

Nick Chubb (Texans)

Over 7.5

-112

Under 7.5

-112

Rushing Yards

Tony Pollard (Titans)

Over 65.5

-112

Under 65.5

-112

Nick Chubb (Texans)

Over 48.5

-112

Under 48.5

-112

Woody Marks (Texans)

Over 28.5

-112

Under 28.5

-112

C.J. Stroud (Texans)

Over 14.5

-112

Under 14.5

-112

Cam Ward (Titans)

Over 9.5

-112

Under 9.5

-112

Passing Yards

C.J. Stroud (Texans)

Over 216.5

-112

Under 216.5

-112

Cam Ward (Titans)

Over 187.5

-112

Under 187.5

-112

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Texans Own Six Victories From Previous Ten at Home

The Texans have six wins and four losses in the last 10 home games, putting up 21.20 points on average and giving up 20.60.

The Titans have been on the losing end in four straight road games. They own a 2-8 mark in their past 10 games away from home, putting up 19.50 points per contest and giving up 29.60.

The last time the Titans faced the Texans at NRG Stadium, they won 32-27. Over the last 6 head-to-head clashes at NRG Stadium, the Titans have recorded five wins, while the Texans have one to their name.

Last 10 Games		W-L	P	PF	PA	O38.5	U38.5
Texans Home Stats		6-4	41.80	21.20	20.60	7	3
Titans Away Stats		2-8	49.10	19.50	29.60	8	2

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O38.5 = Games Over 38.5 Points
• U38.5 = Games Under 38.5 Points

Latest regular season and playoff games stats.

Tennessee Titans Stats

Houston Texans Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +7.5 Betting Line: Have covered the spread in 3 of the last 10 games
• +7.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -7.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -7.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 48.30 pts in the previous 10 games
• Game Totals on the Road: An average of 49.10 pts in the previous 10 games on the road
• Over 38.5: Covered in 6 of the previous 10 games
• Over 38.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 19.20 pts and allowed 29.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 19.50 pts and allowed 29.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 36.10 pts in the previous 10 games
• Game Totals at Home: An average of 41.80 pts in the previous 10 home games
• Over 38.5: Covered in 4 of the previous 10 games
• Over 38.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 17.10 pts and allowed 19.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 21.20 pts and allowed 20.60 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 288.50 Yds. Allowed 363.10 Yds
• Rushing Yards: Gained 95.10 Yds. Allowed 157.90 Yds
• Passing Yards: Gained 193.40 Yds. Allowed 205.20 Yds
• Total Touchdowns: Scored 1.80 TD. Allowed 3.60 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 1.60 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 17.40. Allowed 20.00
• Total Turnovers: Committed 2.00. Committed by opponents 1.60
• Total Penalties: Committed 8.10. Committed by opponents 7.10
• Penalty Yards: Lost 66.10 Yds. Gained 55.50 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 297.00 Yds. Allowed 313.80 Yds
• Rushing Yards: Gained 113.60 Yds. Allowed 103.60 Yds
• Passing Yards: Gained 183.40 Yds. Allowed 210.20 Yds
• Total Touchdowns: Scored 1.60 TD. Allowed 2.10 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 0.90 TD. Allowed 1.20 TD
• Total 1st Downs: Picked up 16.10. Allowed 19.00
• Total Turnovers: Committed 1.30. Committed by opponents 1.20
• Total Penalties: Committed 6.70. Committed by opponents 5.30
• Penalty Yards: Lost 58.60 Yds. Gained 42.60 Yds

Last 10 Games on the Road

• Total Yards: Gained 286.70 Yds. Allowed 304.80 Yds
• Rushing Yards: Gained 111.70 Yds. Allowed 148.80 Yds
• Passing Yards: Gained 175.00 Yds. Allowed 156.00 Yds
• Total Touchdowns: Scored 1.90 TD. Allowed 3.50 TD
• Rushing Touchdowns: Scored 0.70 TD. Allowed 1.50 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.60 TD
• Total 1st Downs: Picked up 17.10. Allowed 18.00
• Total Turnovers: Committed 2.10. Committed by opponents 1.00
• Total Penalties: Committed 8.10. Committed by opponents 6.80
• Penalty Yards: Lost 62.70 Yds. Gained 55.50 Yds

Last 10 Home Games

• Total Yards: Gained 312.80 Yds. Allowed 308.80 Yds
• Rushing Yards: Gained 84.90 Yds. Allowed 130.10 Yds
• Passing Yards: Gained 227.90 Yds. Allowed 178.70 Yds
• Total Touchdowns: Scored 2.00 TD. Allowed 2.20 TD
• Rushing Touchdowns: Scored 0.60 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 16.20. Allowed 18.60
• Total Turnovers: Committed 1.40. Committed by opponents 2.00
• Total Penalties: Committed 7.70. Committed by opponents 5.80
• Penalty Yards: Lost 66.40 Yds. Gained 43.20 Yds

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