Titans vs Colts Prediction, Picks & Odds | 26 Oct 2025

NFL Betting Preview: Titans vs Colts

The Tennessee Titans take on the Indianapolis Colts in this NFL Week 8 clash at Lucas Oil Stadium, with kickoff scheduled for 15:25 on Sunday, October 26. Our betting preview features expert predictions, picks, updated betting odds, head-to-head stats and the latest team news, including injuries.

Our wager is the Colts on the spread. Back them off -14.5 at odds of -110 and be confident that the big favorites can cover the line against the Titans.

See value in our spread recommendation? Snag the best BetMGM promo code and take a moment to read our in-depth site review before locking in your bet.

Tennessee Titans have lost in back-to-back outings. In a recent home game at Nissan Stadium, they were turned over 31-13 by New England Patriots. The Titans put up 255 yards, including 216 passing and 39 rushing yards. They scored once through the air and picked up 16 first downs.

Indianapolis Colts have won four straight home games. In their last appearance, they won on the road, beating Los Angeles Chargers 38-24 at SoFi Stadium. The Colts put up 401 total yards, made up of 281 through the air and 120 on the ground. The offense produced 24 first downs and scored 5 touchdowns, with 2 through the air and 3 on the ground.

Head-to-Head Statistics

The last matchup between the Colts and the Titans saw the former win. It was a 41-20 scoreline at Nissan Stadium. Both teams have five wins on the board when we look at the 10-game H2H record.

Quarterbacks

Cam Ward

207.5 Passing Yards

Over -112

Under -112

Daniel Jones

237.5 Passing Yards

Over -112

Under -112

Titans vs Colts Prediction & Picks

Take in the full Titans vs Colts betting outlook — from our expert match prediction and correct score pick to player prop insights and a bet builder tailored for value.

Game Prediction

Our pick is that the Colts can enjoy a big win in this NFL battle, leading us to go against the spread at -14.5. The line makes plenty of appeal and there are odds of -110 that can be taken for the favorites.

Team news plays a key role in our NFL predictions and we’re always tracking players with injury concerns. We also stay on top of the form guide, supported by detailed stats that help paint a clearer picture of what to expect.

Key Titans vs Colts stats:

• The +14.5 line hasn’t been covered by Titans in 3 of their last 5 games.

Colts -14.5 Probability

The best NFL sportsbooks are suggesting that our pick has a 52.4% chance of landing a return. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 55-60%. It is the reason why we are recommending this wager.

Looking for more juice from your spread pick? By moving the betting line, you are able to get bigger odds although you will need to take a riskier wager.

Boost your wager with the newest free bets, sign-up promotions and the best betting offers featured in our easy-to-use guide.

Our Game Prediction

Colts -14.5 @ -110 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (21:26, 24 October 2025). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Cam Ward Under 206.5 Passing Yards -114

The odds for Cam Ward (Titans) to end with fewer than 206.5 passing yards are -114. He could struggle to reach the QB Passing Yards line, making this prop bet highly appealing.

Latest Cam Ward Player Prop Odds

Touchdown

Anytime

+900

First

+5500

Passing Yards

Over 207.5

-112

Under 207.5

-112

Rushing Yards

Over 5.5

-112

Under 5.5

-112

---

Jonathan Taylor Under 100.5 Rushing Yards -114

The odds for Jonathan Taylor (Titans) to finish with fewer than 100.5 rushing yards are -114. Considering all factors, we’re confident he’ll fall short of the Player Rushing Yards line.

Latest Jonathan Taylor Player Prop Odds

Touchdown

Anytime

-385

First

+200

Receiving Yards

Over 18.5

-112

Under 18.5

-112

Rushing Yards

Over 100.5

-112

Under 100.5

-112

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Titans 7 - 31 Colts

You don’t need a big stake to enjoy a monster return by getting this correct score right. We’re going for the Colts to claim a 31-7 victory and hopefully this goes close.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Titans vs Colts Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The latest Moneyline betting odds give Indianapolis Colts a 64% chance of winning this game which means they’re overwhelming -175 favorites with the sportsbooks. For those wanting to back Tennessee Titans, you will find +145 about the underdogs.

3.5 is where the spread lies, with total points being 44.5 right now. There is no denying the popularity of betting on the Totals. If you’re going for Under 44.5, this outcome can be backed at -110.

You can find a huge selection of game lines and team props for every National Football League showdown, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your wagers.

Moneyline

Titans

+145

Colts

-175

Point Spread

Titans +3.5

-110

Colts -3.5

-110

Total Points

Under 44.5

-110

Over 44.5

-110

Jonathan Taylor is available at -385 when it comes to Anytime Touchdown Scorer. The favorite is now priced at odds of +200 to score the first TD.

Touchdown

Jonathan Taylor (Colts)

First TD

+200

Anytime TD

-385

Tyler Warren (Colts)

First TD

+600

Anytime TD

+110

Michael Pittman Jr. (Colts)

First TD

+750

Anytime TD

+175

Josh Downs (Colts)

First TD

+1200

Anytime TD

+290

Daniel Jones (Colts)

First TD

+1200

Anytime TD

+230

Tony Pollard (Titans)

First TD

+1300

Anytime TD

+170

Alec Pierce (Colts)

First TD

+1300

Anytime TD

+290

Tyjae Spears (Titans)

First TD

+2500

Anytime TD

+330

Ameer Abdullah (Colts)

First TD

+2700

Anytime TD

+340

Elic Ayomanor (Titans)

First TD

+3000

Anytime TD

+400

Chimere Dike (Titans)

First TD

+3300

Anytime TD

+480

Gunnar Helm (Titans)

First TD

+3500

Anytime TD

+430

Chigoziem Okonkwo (Titans)

First TD

+3500

Anytime TD

+500

Van Jefferson (Titans)

First TD

+4000

Anytime TD

+600

Adonai Mitchell (Colts)

First TD

+4500

Anytime TD

+750

Ashton Dulin (Colts)

First TD

+4500

Anytime TD

+750

Tyler Goodson (Colts)

First TD

+5000

Anytime TD

+750

DJ Giddens (Colts)

First TD

+5500

Anytime TD

+750

Cam Ward (Titans)

First TD

+5500

Anytime TD

+900

Will Mallory (Colts)

First TD

+7500

Anytime TD

+1100

Mo Alie-Cox (Colts)

First TD

+7500

Anytime TD

+1200

Drew Ogletree (Colts)

First TD

+8000

Anytime TD

+1600

Anthony Gould (Colts)

First TD

+8000

Anytime TD

+1200

David Martin-Robinson (Titans)

First TD

+10000

Anytime TD

+2000

Julius Chestnut (Titans)

First TD

+10000

Anytime TD

+3500

Mason Kinsey (Titans)

First TD

+10000

Anytime TD

+1800

James Proche II (Titans)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Tyler Warren (Colts)

Over 55.5

-112

Under 55.5

-112

Michael Pittman Jr. (Colts)

Over 47.5

-112

Under 47.5

-112

Alec Pierce (Colts)

Over 37.5

-112

Under 37.5

-112

Elic Ayomanor (Titans)

Over 36.5

-112

Under 36.5

-112

Josh Downs (Colts)

Over 34.5

-112

Under 34.5

-112

Van Jefferson (Titans)

Over 29.5

-112

Under 29.5

-112

Chimere Dike (Titans)

Over 28.5

-112

Under 28.5

-112

Chigoziem Okonkwo (Titans)

Over 27.5

-112

Under 27.5

-112

Gunnar Helm (Titans)

Over 21.5

-112

Under 21.5

-112

Jonathan Taylor (Colts)

Over 18.5

-112

Under 18.5

-112

Tyjae Spears (Titans)

Over 14.5

-112

Under 14.5

-112

Tony Pollard (Titans)

Over 13.5

-112

Under 13.5

-112

Rushing Yards

Jonathan Taylor (Colts)

Over 100.5

-112

Under 100.5

-112

Tony Pollard (Titans)

Over 39.5

-112

Under 39.5

-112

Tyjae Spears (Titans)

Over 20.5

-112

Under 20.5

-112

Daniel Jones (Colts)

Over 14.5

-112

Under 14.5

-112

Cam Ward (Titans)

Over 5.5

-112

Under 5.5

-112

Passing Yards

Daniel Jones (Colts)

Over 237.5

-112

Under 237.5

-112

Cam Ward (Titans)

Over 207.5

-112

Under 207.5

-112

Instead of focusing on the overall outcome, some bettors prefer to look at the NFL micro betting lines. As the name suggests, it means placing short-term wagers and this might include the Next Play or Next Drive Result.

Will Colts Keep Their Home Streak Going?

The Colts have put together six in a row at Lucas Oil Stadium. They have gone 8-2 across their last 10 home games, averaging 26.60 points scored and 21.00 points allowed.

The Titans own a 2-8 mark in their past 10 games away from home, averaging 16.90 points on offense and surrendering 29.30 on defense.

The last time these teams met at Lucas Oil Stadium, the Colts came out on top 38-30 against the Titans. From the past 6 head-to-heads at Lucas Oil Stadium, the Titans have won four while the Colts have taken two.

Last 10 Games		W-L	P	PF	PA	O46.5	U46.5
Colts Home Stats		8-2	47.60	26.60	21.00	6	4
Titans Away Stats		2-8	46.20	16.90	29.30	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O46.5 = Games Over 46.5 Points
• U46.5 = Games Under 46.5 Points

Latest regular season and playoff games stats.

Tennessee Titans Stats

Indianapolis Colts Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +14.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +14.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -14.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -14.5 Betting Line at Home: Have covered the spread in 2 of the last 10 home games

Total Points

• Game Totals: An average of 42.60 pts in the previous 10 games
• Game Totals on the Road: An average of 46.20 pts in the previous 10 games on the road
• Over 46.5: Covered in 3 of the previous 10 games
• Over 46.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 15.30 pts and allowed 27.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 16.90 pts and allowed 29.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 56.70 pts in the previous 10 games
• Game Totals at Home: An average of 47.60 pts in the previous 10 home games
• Over 46.5: Covered in 8 of the previous 10 games
• Over 46.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 32.90 pts and allowed 23.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 26.60 pts and allowed 21.00 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 260.70 Yds. Allowed 357.40 Yds
• Rushing Yards: Gained 83.90 Yds. Allowed 164.10 Yds
• Passing Yards: Gained 176.80 Yds. Allowed 193.30 Yds
• Total Touchdowns: Scored 1.30 TD. Allowed 3.30 TD
• Rushing Touchdowns: Scored 0.40 TD. Allowed 1.70 TD
• Passing Touchdowns: Scored 0.80 TD. Allowed 1.30 TD
• Total 1st Downs: Picked up 16.20. Allowed 19.30
• Total Turnovers: Committed 1.70. Committed by opponents 1.10
• Total Penalties: Committed 6.70. Committed by opponents 5.90
• Penalty Yards: Lost 51.70 Yds. Gained 41.70 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 399.50 Yds. Allowed 343.50 Yds
• Rushing Yards: Gained 154.90 Yds. Allowed 89.00 Yds
• Passing Yards: Gained 244.60 Yds. Allowed 254.50 Yds
• Total Touchdowns: Scored 3.80 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 2.00 TD. Allowed 0.70 TD
• Passing Touchdowns: Scored 1.40 TD. Allowed 2.00 TD
• Total 1st Downs: Picked up 23.30. Allowed 20.40
• Total Turnovers: Committed 0.80. Committed by opponents 1.50
• Total Penalties: Committed 5.90. Committed by opponents 6.00
• Penalty Yards: Lost 48.10 Yds. Gained 58.00 Yds

Last 10 Games on the Road

• Total Yards: Gained 282.30 Yds. Allowed 326.60 Yds
• Rushing Yards: Gained 97.70 Yds. Allowed 158.90 Yds
• Passing Yards: Gained 184.60 Yds. Allowed 167.70 Yds
• Total Touchdowns: Scored 1.70 TD. Allowed 3.60 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 1.70 TD
• Passing Touchdowns: Scored 1.10 TD. Allowed 1.70 TD
• Total 1st Downs: Picked up 16.60. Allowed 19.00
• Total Turnovers: Committed 2.10. Committed by opponents 1.20
• Total Penalties: Committed 7.40. Committed by opponents 6.60
• Penalty Yards: Lost 56.00 Yds. Gained 48.60 Yds

Last 10 Home Games

• Total Yards: Gained 372.10 Yds. Allowed 340.30 Yds
• Rushing Yards: Gained 158.60 Yds. Allowed 115.00 Yds
• Passing Yards: Gained 213.50 Yds. Allowed 225.30 Yds
• Total Touchdowns: Scored 2.80 TD. Allowed 2.50 TD
• Rushing Touchdowns: Scored 1.30 TD. Allowed 1.20 TD
• Passing Touchdowns: Scored 1.20 TD. Allowed 1.10 TD
• Total 1st Downs: Picked up 21.30. Allowed 20.70
• Total Turnovers: Committed 0.70. Committed by opponents 1.70
• Total Penalties: Committed 6.10. Committed by opponents 5.70
• Penalty Yards: Lost 47.00 Yds. Gained 52.20 Yds

Top American Football Pages