Buffalo vs DePaul Prediction, Picks & Odds | 11 Nov 2025

College Basketball Betting Preview: Buffalo vs DePaul

The Buffalo Bulls face the DePaul Blue Demons, with tip-off scheduled for 20:00 on Tuesday, November 11. Our betting preview features expert NCAAB predictions, betting tips, the latest odds and H2H stats.

Bet Against Points

We’re going for a modest total when Buffalo and DePaul take to the court. Under 154.5 points could be on the money and our prediction is currently available at -112.

Riding with our Totals pick? Read our in-depth BetMGM review and grab the latest promo code before you place your bet.

Buffalo Too Strong for DePaul in Last H2H

Buffalo Bulls won their previous game which was at home. It was a 83-76 triumph against Green Bay Phoenix.

DePaul Blue Demons won their last game which was at home. It was a 72-64 triumph against Stonehill Skyhawks.

Head-to-Head Statistics

Buffalo triumphed 74-69 when they last played DePaul.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
DePaul	2-0	164	126	38	2-0	0-0	2W
Buffalo	2-0	168	155	13	2-0	0-0	2W

View Full Standings

Buffalo vs DePaul Prediction & Picks

Our Buffalo vs DePaul betting preview covers everything you need, including a key match prediction, correct score insight and a value-packed bet builder recommendation.

Game Prediction

Under 154.5 points could be on the money for this college game. Our pick is based on a low-scoring contest and the odds of -112 looks like a value bet.

Injuries can influence the outcome and our college basketball handicappers factor that in alongside the latest form guide. We apply the same approach to the stats to build the clearest picture of how the game might unfold.

Key Buffalo vs DePaul stats:

• The 154.5 line hasn’t been covered in 3 of the last 5 Buffalo games on the road.
• The 154.5 line hasn’t been covered in 4 of the last 5 DePaul games.
• The 154.5 line hasn’t been covered in 7 of the last 10 DePaul games at home.
• The 154.5 line hasn’t been covered in the last 3 DePaul games.

Under 154.5 Probability

The best betting sites suggest there’s a 52.9% chance of our pick delivering a return. Taking all factors into consideration, our cappers think there’s a stronger chance of success and estimate the probability to be closer to 60%. That means we’re regarding it as a value bet.

If you’re wanting to wager Under on the Totals, then you can aim for bigger odds. In order to do this, you simply move the line to where you feel a winning return can still be found.

Before you place your bets, explore our updated guide packed with the latest free bets and betting bonuses.

Best Bet

Under 154.5 Points @ -112 Bet Now

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Correct Score Prediction

Buffalo 67 - 82 DePaul

If you want to achieve a big return from your stake, then it’s worth checking out the correct score lines. the Blue Demons to claim a 82-67 victory is on offer at huge betting odds.

Buffalo vs DePaul Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

DePaul Heavy Favorites to Win

DePaul are strong -10000 favorites to win this college game according to the Moneyline betting odds. The sportsbooks give them a 99% chance of claiming victory. Buffalo are the underdogs at +1800 and they’re regarded as least likely to win.

The spread is currently 18.5, with the total points line at 153.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. There’s the chance to back Under 153.5 at -114.

The top basketball sportsbooks offer a huge selection of game lines and team props when it comes to most college games. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Buffalo

+1800

DePaul

-10000

Point Spread

Buffalo +18.5

-110

DePaul -18.5

-110

Total Points

Under 153.5

-114

Over 153.5

-110

Player Props & Micro Betting

You shouldn’t overlook the player props when it comes to betting on individual games. Many gambling sites will give you the chance to get with or bet against a specific player when it comes to number of Points, Assists, Steals and Blocks.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Last 5 & H2H

Latest regular season and playoff games stats.

Buffalo Stats

DePaul Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• +17.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +17.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -17.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -17.5 Betting Line at Home: Have covered the spread in 1 of the last 10 home games

Total Points

• Game Totals: An average of 150.60 pts in the previous 10 games
• Game Totals on the Road: An average of 154.90 pts in the previous 10 games on the road
• Over 154.5: Covered in 5 of the previous 10 games
• Over 154.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 72.50 pts and allowed 78.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 72.50 pts and allowed 82.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 149.10 pts in the previous 10 games
• Game Totals at Home: An average of 141.50 pts in the previous 10 home games
• Over 154.5: Covered in 4 of the previous 10 games
• Over 154.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 73.50 pts and allowed 75.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 69.50 pts and allowed 72.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
UConn	3-0	278	164	114	3-0	0-0	3W
Marquette	3-0	280	212	68	2-0	1-0	3W
Butler	2-0	200	138	62	2-0	0-0	2W
Seton Hall	3-0	227	170	57	3-0	0-0	3W
DePaul	2-0	164	126	38	2-0	0-0	2W
Georgetown	2-0	157	130	27	1-0	1-0	2W
Creighton	1-0	92	76	16	1-0	0-0	1W
Xavier	2-1	208	218	-10	2-1	0-0	1L
St. John's	1-1	204	177	27	1-1	0-0	1L
Villanova	1-1	160	145	15	1-0	0-1	1W
Providence	1-1	190	186	4	1-0	0-1	1L

Mid-American	Overall	PF	PA	N. Pts	Home	Away	Strk
Bowling Green	3-0	286	173	113	3-0	0-0	3W
Miami (OH)	2-0	216	121	95	2-0	0-0	2W
Ball State	2-0	159	118	41	2-0	0-0	2W
Buffalo	2-0	168	155	13	2-0	0-0	2W
Kent State	2-1	293	282	11	2-1	0-0	2W
UMass	1-1	155	140	15	1-1	0-0	1W
Eastern Michigan	1-1	137	127	10	1-0	0-1	1L
Ohio	1-1	157	157	0	1-1	0-0	1W
Central Michigan	1-1	136	151	-15	1-0	0-1	1L
Akron	1-1	154	175	-21	1-1	0-0	1L
Western Michigan	1-2	239	247	-8	1-1	0-1	2L
Northern Illinois	1-2	233	267	-34	1-0	0-2	2L
Toledo	0-2	147	161	-14	0-2	0-0	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak