Clemson vs Duke Prediction, Picks & Odds | 14 Feb 2026

College Basketball Betting Preview: Clemson vs Duke

The Clemson Tigers battle the Duke Blue Devils, with tip-off scheduled for 12:00 on Saturday, February 14.

The best betting angle could be wagering on the totals when Clemson clash with Duke. Our prediction is for Over 133.5 points to be scored at odds of -110.

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Clemson Tigers were defeated in their previous game. They were beaten at home to Virginia Tech by a 76-66 scoreline.

Duke Blue Devils won their last game 70-54. This was a road victory against Pittsburgh Panthers.

Head-to-Head Statistics

Clemson beat Duke in their last head-to-head matchup. It was a 77-71 scoreline. In the past 9 games between the teams, Duke have won six.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	22-2	1989	1524	465	13-0	9-2	1W
Clemson	20-5	1891	1615	276	13-2	7-3	1L

View Full Standings

Clemson vs Duke Prediction & Picks

Our expert Clemson vs Duke betting tips include a main match prediction, a correct score pick and bet builder advice. Explore each section below for detailed insights.

Game Prediction

We’re confident that Over 133.5 is the value play at -110. We’re expecting these college teams to rack up the points, so a total wager could be the way forward.

We’re always on top of team news and when combined with recent form, it helps us uncover the best value. Our college basketball handicappers also take a data-led approach, using key stats to back every pick.

Key Clemson vs Duke stats:

• The 133.5 line has been covered in 6 of the last 10 Clemson games on the road.
• The 133.5 line has been covered in 3 of the last 5 Clemson games on the road.
• The 133.5 line has been covered in 18 of the last 20 Duke games at home.
• The 133.5 line has been covered in 8 of the last 10 Duke games at home.
• The 133.5 line has been covered in the last 5 games between these teams.

Over 133.5 Probability

The best betting sites suggest there’s a 52.4% chance of our pick delivering a return. Based on our in-depth research, we calculate the actual probability to be closer to 60%. It’s the reason why we are recommending this college basketball bet.

There’s a chance to secure larger odds when you wager on the Totals. The leading sportsbooks allow you to move the line for an Over pick until you’re happy with the potential return.

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Our Game Prediction

Over 133.5 Points @ -110 Bet Now

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Correct Score Prediction

Clemson 64 - 73 Duke

There are lots of different betting angles including the chance to back Duke on the correct score lines. For example, a 73-64 victory in their favor is available at massive odds.

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Clemson vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

According to the Moneyline betting odds, Duke are red-hot -1250 favorites with the sportsbooks and that means a 93% chance of winning this college game. For those wanting to back Clemson, you will find +720 about the underdogs.

12.5 is where the spread lies, with total points being 133.5 right now. The advantage of the Totals is that you only have to choose from one of two options. If you’re wanting to back Over 133.5, the odds are -110.

The good news is that you can access a wide range of team props and game lines for most college basketball contests. The best betting apps have a huge range of pre-game and in-game wagering options.

Moneyline

Clemson

+720

Duke

-1250

Point Spread

Clemson +12.5

-102

Duke -12.5

-120

Total Points

Under 133.5

-110

Over 133.5

-110

Prop bets don’t involve betting on a team to win and instead might look at a player’s individual performance. For example, the number of Points they might score or the number of Assists they might have.

Micro betting provides a rollercoaster ride for college basketball bettors. It can be great to enjoy the live lines, with the opportunity to bet on the Next Field Goal. Watch the live action before deciding which way to go.

Latest regular season and playoff games stats.

Clemson Stats

Duke Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +12.5 Betting Line: Have covered the spread in the last 10 games
• +12.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road

Point Spread

• -12.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -12.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 134.80 pts in the previous 10 games
• Game Totals on the Road: An average of 145.40 pts in the previous 10 games on the road
• Over 133.5: Covered in 5 of the previous 10 games
• Over 133.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 71.80 pts and allowed 63.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 75.20 pts and allowed 70.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 137.40 pts in the previous 10 games
• Game Totals at Home: An average of 146.90 pts in the previous 10 home games
• Over 133.5: Covered in 5 of the previous 10 games
• Over 133.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 76.70 pts and allowed 60.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 84.20 pts and allowed 62.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	22-2	1989	1524	465	13-0	9-2	1W
Virginia	21-3	1965	1619	346	13-1	8-2	5W
Clemson	20-5	1891	1615	276	13-2	7-3	1L
Miami	19-5	2012	1676	336	13-3	6-2	2W
North Carolina	19-5	1966	1696	270	15-0	4-5	1L
Louisville	18-6	2090	1702	388	13-2	5-4	4W
NC State	18-7	2133	1857	276	11-4	7-3	1L
SMU	17-7	2077	1860	217	14-2	3-5	2W
Virginia Tech	17-8	1989	1851	138	13-2	4-6	1W
California	17-8	1967	1822	145	15-3	2-5	2L
Stanford	16-9	1898	1818	80	10-6	6-3	2W
Syracuse	14-11	1910	1798	112	11-4	3-7	1W
Wake Forest	12-12	1924	1862	62	8-6	4-6	1W
Florida State	11-13	1917	1891	26	9-7	2-6	1L
Notre Dame	11-14	1852	1835	17	9-5	2-9	5L
Georgia Tech	11-14	1863	1895	-32	10-7	1-7	6L
Boston College	9-15	1611	1647	-36	8-9	1-6	5L
Pittsburgh	9-16	1753	1787	-34	7-9	2-7	4L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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