Clemson vs Duke Prediction, Picks & Odds | 13 Mar 2026

College Basketball Betting Preview: Clemson vs Duke

The Clemson Tigers face the Duke Blue Devils, with tip-off scheduled for 20:30 on Friday, March 13.

We’re forecasting that Clemson and Duke will produce a significant combined points total. Therefore, our prediction is to take the -115 that there are Over 134.5 points.

Clemson Tigers won their previous game by a 80-79 scoreline. It was on the road against North Carolina Tar Heels.

Duke Blue Devils last game saw them claim a 80-79 home win over Florida State Seminoles.

Head-to-Head Statistics

It was Duke who came out on top when they last played Clemson. A 67-54 win was recorded. The past 10 games between the teams have seen Duke win seven times.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	30-2	2651	2016	635	19-0	11-2	9W
Clemson	24-9	2460	2196	264	16-3	8-6	3W

View Full Standings

Clemson vs Duke Prediction & Picks

Our Clemson vs Duke betting guide delivers expert insight, including a main match pick, our correct score angle and bet builder recommendations. Dive into each section below for more.

Game Prediction

The two teams should be able to accumulate enough points for our pick to win. We’re forecasting Over 134.5 and odds of -115 are available for this college showdown.

We closely track recent form and look for patterns that may impact the outcome. The same goes for injuries to key players. When combined with the most relevant college hoops stats, this gives us a strong foundation for accurate basketball picks.

Key Clemson vs Duke stats:

• The 134.5 line has been covered in 6 of the last 10 Clemson games.
• The 134.5 line has been covered in 3 of the last 5 Clemson games.
• The 134.5 line has been covered in 4 of the last 5 Duke games.
• The 134.5 line has been covered in 15 of the last 20 Duke games at home.
• The 134.5 line has been covered in the last 3 Duke games.

Over 134.5 Probability

According to the best betting apps, our pick has a 53.5% chance of delivering a return. After careful examination, our analysts have this probability close to 60%. It’s why we think it’s worth placing this college basketball wager.

In order to land bigger odds on your Overs wager, it’s possible to combine this with the winning team. The Match Result & Total lines can provide a larger potential payout.

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Our Game Prediction

Over 134.5 Points @ -115 Bet Now

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Correct Score Prediction

Clemson 62 - 77 Duke

For those wanting a big return from a small stake, consider the correct score lines. For example, Duke can be backed to win 77-62 at huge betting odds.

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Clemson vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Duke are massive -833 favorites. They are regarded as 89% likely to win this college game judging by the sportsbooks’ latest Moneyline odds. Clemson are the underdogs at +570 and they’re regarded as least likely to win.

The current spread is 11.5 and total points is 134.5. Basketball bettors love the chance to get an alternative angle by going for a Total wager. If you want to wager Over 134.5, there are odds of -115.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

Clemson

+570

Duke

-833

Point Spread

Clemson +11.5

-110

Duke -11.5

-110

Total Points

Under 134.5

-105

Over 134.5

-115

As an alternative to the game lines, check out the player prop bets that are available. It’s especially great if you have a view when it comes to Turnovers, Steals, Blocks and Points, while there are lots of other options.

Micro betting is something that’s really popular with bettors, with college basketball fans essentially being able to wager in-game when it comes to score, player and team props. Check out the two-way lines where you can bet whether the next shot will be a Two-pointer or a Three-pointer.

Latest regular season and playoff games stats.

Clemson Stats

Duke Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +11.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +11.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -11.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -11.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 142.40 pts in the previous 10 games
• Game Totals on the Road: An average of 137.70 pts in the previous 10 games on the road
• Over 134.5: Covered in 6 of the previous 10 games
• Over 134.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 71.20 pts and allowed 71.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 70.70 pts and allowed 67.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 141.70 pts in the previous 10 games
• Game Totals at Home: An average of 140.80 pts in the previous 10 home games
• Over 134.5: Covered in 6 of the previous 10 games
• Over 134.5 at Home: Covered in 6 of the previous 10 home games
• Team Totals: Have scored an average of 80.00 pts and allowed 61.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 79.10 pts and allowed 61.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	30-2	2651	2016	635	19-0	11-2	9W
Virginia	28-4	2588	2190	398	18-1	10-3	3W
Miami	25-7	2642	2265	377	16-4	9-3	1W
North Carolina	24-8	2553	2282	271	19-1	5-7	2L
Clemson	24-9	2460	2196	264	16-3	8-6	3W
Louisville	23-10	2797	2382	415	16-2	7-8	1L
California	21-11	2492	2344	148	17-4	4-7	2L
Stanford	20-12	2431	2326	105	12-7	8-5	1L
NC State	20-13	2762	2525	237	13-7	7-6	1L
SMU	20-13	2779	2561	218	17-3	3-10	1L
Virginia Tech	19-13	2521	2396	125	15-4	4-9	2L
Florida State	18-15	2652	2572	80	12-8	6-7	1L
Wake Forest	17-16	2602	2543	59	12-6	5-10	1L
Syracuse	15-17	2400	2376	24	12-6	3-11	6L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	13-20	2327	2370	-43	8-10	5-10	1L
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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