DePaul vs Xavier Prediction, Picks & Odds | 31 Jan 2026

College Basketball Betting Preview: DePaul vs Xavier

The DePaul Blue Demons go up against the Xavier Musketeers, with tip-off scheduled for 13:00 on Saturday, January 31.

With DePaul capable of remaining close to Xavier, backing them on the spread could be the best way forward. -102 is available that the +3.5 is covered.

Confident in our spread pick? Read our in-depth review of BetMGM, then grab the latest promo code before placing your bet.

DePaul Blue Demons were defeated in their previous game. On the road, they suffered a 70-61 reverse against Georgetown Hoyas.

Xavier Musketeers were defeated in their last game. On the road, they suffered a 86-68 reverse against Seton Hall Pirates.

Head-to-Head Statistics

The scoreline was 86-77 in favor of DePaul when they last played Xavier. The previous 10 H2H meetings have involved Xavier winning seven times.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
DePaul	12-9	1527	1459	68	11-4	1-5	1L
Xavier	11-10	1638	1630	8	10-5	1-5	3L

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DePaul vs Xavier Prediction & Picks

Take on DePaul vs Xavier with our in-depth betting analysis, featuring an expert match prediction, scoreline advice and a value-driven bet builder. Scroll down for the full breakdown.

Game Prediction

We’re confident that the underdogs can either win or suffer a narrow defeat in this college contest. That makes DePaul at +3.5 the best wager and -102 are available.

The handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our basketball predictions. We combine this insight with up-to-date college hoops stats for sharper picks.

Key DePaul vs Xavier stats:

• The +3.5 line has been covered by DePaul in 12 of their last 20 games.
• The -3.5 line hasn’t been covered by Xavier in 8 of their last 10 games.
• The -3.5 line hasn’t been covered by Xavier in 11 of their last 20 games.
• The -3.5 line hasn’t been covered by Xavier in 3 consecutive games.

DePaul +3.5 Probability

According to the top sportsbooks, our pick has a 50.5% chance of winning. Our analysts think there’s a stronger chance of success and calculate the probability to be 55-60%. It’s why we think it’s worth placing this college basketball bet.

If you’re looking for a bigger potential return on your stake, there is always the option to move the line. Consider the odds and whether each line can be covered.

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Our Game Prediction

DePaul +3.5 @ -102 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (18:56, 30 January 2026). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

DePaul 78 - 77 Xavier

We’re expecting this to be a close game and we’ll take the Blue Demons to win 78-77. This is available at huge odds for those that want to have a speculative wager.

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DePaul vs Xavier Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Xavier have the shortest price to win this college game, with the sportsbooks giving them a 68% probability due to their -208 Moneyline betting odds. At +172, DePaul are regarded as having a lower probability of winning.

The spread currently stands at 3.5 and the total points line is 150.5. A Total wager relates to the number of points that will be scored overall. If you fancy Over 150.5, this outcome can be backed at -110.

Consider every angle when placing your college basketball bets. The top betting apps offer a nice selection of team props and game lines and it’s all about finding a wager which matches your prediction of the contest.

Moneyline

DePaul

+172

Xavier

-208

Point Spread

DePaul +3.5

-102

Xavier -3.5

-120

Total Points

Under 150.5

-110

Over 150.5

-110

If you’re looking for an alternative to the main game lines, check out the player props instead. It’s great to wager on Total Points, Three-Pointers, Assists, Steals, Blocks and Rebounds as potential options.

There are always opportunities to enjoy college basketball micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as if the next shot will be a Two or Three-Pointer.

Latest regular season and playoff games stats.

DePaul Stats

Xavier Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +3.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +3.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• -3.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -3.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 138.90 pts in the previous 10 games
• Game Totals on the Road: An average of 143.60 pts in the previous 10 games on the road
• Over 150.5: Covered in 3 of the previous 10 games
• Over 150.5 on the Road: Covered in 3 of the previous 10 games on the road
• Team Totals: Have scored an average of 67.60 pts and allowed 71.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 68.70 pts and allowed 74.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 162.00 pts in the previous 10 games
• Game Totals at Home: An average of 158.40 pts in the previous 10 home games
• Over 150.5: Covered in 9 of the previous 10 games
• Over 150.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 77.60 pts and allowed 84.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 80.90 pts and allowed 77.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
UConn	20-1	1653	1350	303	12-1	8-0	16W
St. John's	16-5	1793	1523	270	10-3	6-2	7W
Villanova	16-5	1635	1452	183	11-2	5-3	1W
Seton Hall	15-6	1517	1349	168	9-3	6-3	1W
Butler	13-8	1741	1610	131	12-3	1-5	1L
Creighton	12-9	1642	1573	69	10-2	2-7	1L
DePaul	12-9	1527	1459	68	11-4	1-5	1L
Georgetown	11-10	1581	1539	42	8-5	3-5	2W
Xavier	11-10	1638	1630	8	10-5	1-5	3L
Providence	9-13	1937	1895	42	7-5	2-8	4L
Marquette	8-14	1679	1723	-44	8-6	0-8	1W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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