East Carolina vs Charlotte Prediction, Picks & Odds | 21 Feb 2026

College Basketball Betting Preview: East Carolina vs Charlotte

The East Carolina Pirates square off against the Charlotte 49ers, with tip-off scheduled for 12:00 on Saturday, February 21.

We’re expecting Over 145.5 points to be scored by East Carolina and Charlotte combined. There’s a juicy -105 for our prediction and we’re anticipating that the scoreboard will tick over.

East Carolina Pirates lost their previous game, being beaten at home to Wichita State Shockers 92-89 (OT).

Charlotte 49ers were defeated in their last game. On the road, they suffered a 79-74 reverse against Tulsa Golden Hurricane.

Head-to-Head Statistics

The scoreline was 73-70 in favor of Charlotte when they last played East Carolina. The previous 8 games have seen both teams achieve four victories.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Charlotte	13-13	1913	1931	-18	9-6	4-7	4L
East Carolina	9-17	1846	2001	-155	6-11	3-6	1L

View Full Standings

East Carolina vs Charlotte Prediction & Picks

This East Carolina vs Charlotte betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.

Game Prediction

The total line looks to be on the low side at 145.5. There’s a strong chance that the college rivals will conspire to go above the line and we’re backing Over at -105.

We track all injuries that could impact each team before making our basketball picks. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the college hoops action.

Key East Carolina vs Charlotte stats:

• The 145.5 line has been covered in the last 6 East Carolina games.
• The 145.5 line has been covered in 7 of the last 10 East Carolina games.
• The 145.5 line has been covered in 11 of the last 20 East Carolina games.
• The 145.5 line has been covered in 4 of the last 5 Charlotte games at home.
• The 145.5 line has been covered in 7 of the last 10 Charlotte games at home.
• The 145.5 line has been covered in the last 2 Charlotte games.

Over 145.5 Probability

When you look at the latest odds, our pick has a 51.3% chance of landing a return. Our analysts think there’s a stronger chance of success and calculate the probability to be closer to 60%. It’s why we think it’s worth placing this college basketball bet.

There are ways to get bigger odds by betting Over on the Totals. Bettors often look to move the line so they can land a more profitable return if the selection wins.

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Our Game Prediction

Over 145.5 Points @ -105 Bet Now

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Correct Score Prediction

East Carolina 75 - 77 Charlotte

We’re expecting a close contest so it might be worth going for Charlotte to win by a 77-75 scoreline. You can get a massive price and we should hopefully get a run for our money.

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East Carolina vs Charlotte Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Charlotte are regarded as having a 74% chance of winning this college game according to the latest betting odds. The sportsbooks have priced them up at -278. For those wanting to oppose the market leader, you can get +220 about East Carolina.

The current spread is 5.5 and the total points line is 145.5. A Total bet is always available and can often provide value selections. If you're keen on Over 145.5, this selection is available at -105.

There are plenty of team props and game lines when it comes to wagering on college matchups and we recommend visiting the best basketball sportsbooks to find the wager that matches your view on the game.

Moneyline

East Carolina

+220

Charlotte

-278

Point Spread

East Carolina +5.5

-102

Charlotte -5.5

-120

Total Points

Under 145.5

-115

Over 145.5

-105

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

There are always opportunities to enjoy college basketball micro betting. It’s generally the case that you will find player and team props in-game and bettors can use their insight to wager on outcomes such as if the next shot will be a Two or Three-Pointer.

Latest regular season and playoff games stats.

East Carolina Stats

Charlotte Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +5.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +5.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• -5.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -5.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 152.10 pts in the previous 10 games
• Game Totals on the Road: An average of 149.00 pts in the previous 10 games on the road
• Over 145.5: Covered in 7 of the previous 10 games
• Over 145.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 75.20 pts and allowed 76.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 68.20 pts and allowed 80.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 148.80 pts in the previous 10 games
• Game Totals at Home: An average of 154.80 pts in the previous 10 home games
• Over 145.5: Covered in 6 of the previous 10 games
• Over 145.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 72.50 pts and allowed 76.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 77.90 pts and allowed 76.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

American Athletic Conference	Overall	PF	PA	N. Pts	Home	Away	Strk
Tulsa	21-6	2305	1972	333	12-2	9-4	1W
South Florida	19-8	2395	2106	289	12-4	7-4	5W
Wichita State	17-10	2097	1910	187	12-5	5-5	2W
UAB	17-10	2151	1992	159	8-8	9-2	1W
Tulane	16-10	1894	1910	-16	9-7	7-3	3W
Temple	15-11	1938	1837	101	9-6	6-5	3L
Florida Atlantic	15-12	2167	2010	157	9-6	6-6	1W
North Texas	15-12	1907	1797	110	10-5	5-7	1L
Charlotte	13-13	1913	1931	-18	9-6	4-7	4L
Memphis	12-14	1936	1932	4	10-4	2-10	3L
Rice	11-15	1942	1948	-6	8-7	3-8	1L
East Carolina	9-17	1846	2001	-155	6-11	3-6	1L
UTSA	5-21	1791	2076	-285	2-10	3-11	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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