Eastern Illinois vs Southern Indiana Prediction, Picks & Odds | 22 Jan 2026

College Basketball Betting Preview: Eastern Illinois vs Southern Indiana

The Eastern Illinois Panthers go up against the Southern Indiana Screaming Eagles, with tip-off scheduled for 20:30 on Thursday, January 22.

Our best bet is Eastern Illinois to cover the spread. +2.5 at odds of -112 look more than generous and we’re happy to back them with this advantage against Southern Indiana.

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Eastern Illinois Panthers claimed a victory in their previous game. A 105-49 home win occurred against Blackburn Beavers.

Southern Indiana Screaming Eagles lost on the road in their last game. Tennessee State Tigers won 73-67.

Head-to-Head Statistics

Eastern Illinois triumphed 63-54 when they last played Southern Indiana. The previous 5 games featuring these teams have resulted in three Eastern Illinois victories.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Eastern Illinois	8-11	1285	1338	-53	8-2	0-9	1W
Southern Indiana	4-14	1265	1346	-81	2-5	2-9	1L

View Full Standings

Eastern Illinois vs Southern Indiana Prediction & Picks

Step into Eastern Illinois vs Southern Indiana with confidence, armed with our expert match prediction, likely scoreline and a custom-built bet builder for maximum value.

Game Prediction

We wouldn’t be surprised to see the Eastern Illinois triumph in this college matchup. In terms of landing extra value, it makes sense to take +2.5 when it comes to the spread at -112.

The formbook is always a smart starting point when making basketball predictions. Up-to-date college hoops team news is just as important, while the stats we provide often reveal valuable insights.

Key Eastern Illinois vs Southern Indiana stats:

• The +2.5 line has been covered by Eastern Illinois in 4 of their last 5 games.
• The +2.5 line has been covered by Eastern Illinois in 6 of their last 10 games.
• The -2.5 line hasn’t been covered by USI in 4 consecutive games at home.
• The -2.5 line hasn’t been covered by USI in 9 of their last 10 games.
• The -2.5 line hasn’t been covered by USI in 16 of their last 20 games.
• The -2.5 line hasn’t been covered by USI in 3 of their last 5 games against Eastern Illinois.

Eastern Illinois +2.5 Probability

Based on the latest odds from the top sportsbooks, our pick carries a 52.9% chance of winning. In our opinion, there’s actually a probability of success between 55-60%. That means we’re regarding it as a value bet.

There’s an opportunity to secure bigger odds and this can be achieved by moving the line. Squeeze more juice from your pick by taking an alternative wagering view.

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Our Game Prediction

Eastern Illinois +2.5 @ -112 Bet Now

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Correct Score Prediction

Eastern Illinois 72 - 68 Southern Indiana

There are massive odds on offer when it comes to Eastern Illinois landing a 72-68 win. A close game is anticipated between two evenly-matched teams.

Eastern Illinois vs Southern Indiana Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Some sportsbooks won’t be offering Moneyline wagering for this college game considering Eastern Illinois are massive underdogs. Many bettors like to consider the Spread as an alternative, with this suiting all types of bankroll.

The spread is currently 2.5, with the total points line at 134.5. There are many ways to bet on basketball including the Totals. There’s an opportunity to bet Over 134.5 at -110.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Eastern Illinois

-

USI

-

Point Spread

Eastern Illinois +2.5

-112

USI -2.5

-108

Total Points

Under 134.5

-110

Over 134.5

-110

We’re fond of player props as an alternative to betting on the game result. The gambling sites will have Points, Assists, Three-Pointers, Rebounds and Steals among the choices and you can take a particular view.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Latest regular season and playoff games stats.

Eastern Illinois Stats

Southern Indiana Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 1 win and 9 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 6 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 1 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 137.70 pts in the previous 10 games
• Game Totals on the Road: An average of 137.90 pts in the previous 10 games on the road
• Over 134.5: Covered in 5 of the previous 10 games
• Over 134.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 72.90 pts and allowed 64.80 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 59.90 pts and allowed 78.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 139.10 pts in the previous 10 games
• Game Totals at Home: An average of 144.10 pts in the previous 10 home games
• Over 134.5: Covered in 5 of the previous 10 games
• Over 134.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 65.70 pts and allowed 73.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 72.30 pts and allowed 71.80 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Ohio Valley	Overall	PF	PA	N. Pts	Home	Away	Strk
UT Martin	15-5	1459	1286	173	9-0	6-5	1L
Tennessee State	12-6	1465	1377	88	6-1	6-5	2W
Lindenwood	11-8	1519	1366	153	7-1	4-7	1L
SIU Edwardsville	11-8	1393	1247	146	5-4	6-4	1W
Southeast Missouri	10-10	1519	1461	58	6-4	4-6	1W
Little Rock	9-10	1363	1451	-88	5-2	4-8	4W
Morehead State	9-10	1470	1483	-13	5-1	4-9	1W
Eastern Illinois	8-11	1285	1338	-53	8-2	0-9	1W
Tennessee Tech	7-12	1414	1454	-40	4-5	3-7	2L
Southern Indiana	4-14	1265	1346	-81	2-5	2-9	1L
Western Illinois	3-15	1175	1362	-187	2-5	1-10	8L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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