Florida State vs Clemson Prediction, Picks & Odds | 21 Feb 2026

College Basketball Betting Preview: Florida State vs Clemson

The Florida State Seminoles face the Clemson Tigers, with tip-off scheduled for 12:00 on Saturday, February 21.

Our prediction is that Florida State can outperform their odds against Clemson. It leads us to a bet on the spread lines considering that +9.5 has been chalked up at -110.

Florida State Seminoles previous game saw them claim a 80-72 home win over Boston College Eagles.

Clemson Tigers were beaten last game and this was on the road. Wake Forest Demon Deacons claimed a 85-77 win.

Head-to-Head Statistics

Clemson beat FSU when the teams last met. It was a 72-46 scoreline. Clemson have six straight victories against FSU. They have won 8 of the 10 previous head-to-head matchups.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Clemson	20-7	2022	1767	255	13-2	7-5	3L
Florida State	13-13	2089	2032	57	10-7	3-6	2W

View Full Standings

Florida State vs Clemson Prediction & Picks

Make the most of Florida State vs Clemson with our betting analysis that includes an expert match prediction, expected scoreline and a hand-picked bet builder designed for value.

Game Prediction

We’re expecting a spirited performance from Florida State which leads us to backing them against the spread for this college matchup. The underdogs should be able to cover the +9.5 line where -110 can be found.

To deliver the best possible basketball picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date college hoops stats available.

Key Florida State vs Clemson stats:

• The +9.5 line has been covered by FSU in 10 consecutive games.
• The +9.5 line has been covered by FSU in 14 of their last 20 games.
• The -9.5 line hasn’t been covered by Clemson in 4 of their last 5 games.
• The -9.5 line hasn’t been covered by Clemson in 13 of their last 20 games.
• The -9.5 line hasn’t been covered by Clemson in 3 consecutive games.

FSU +9.5 Probability

If you go by the top sportsbooks, our pick has a 52.4% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and estimate the probability to be closer to 60%. It’s why we think it’s worth placing this college basketball wager.

In the hunt for bigger odds, you might be interested to know that you can move the line. This allows you to shoot for a team to perform better than expected by the sportsbooks.

Before you back your picks, see how far a bonus can take you — our guide highlights the top betting offers live now.

Our Game Prediction

FSU +9.5 @ -110 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Feb 20, 17:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Florida State 72 - 79 Clemson

There’s lots of entertainment when it comes to a correct score wager. A play on Clemson to achieve a 79-72 victory should give bettors a good run for their money.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Florida State vs Clemson Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The sportsbooks are taking no chances with their Moneyline odds of -556 about Clemson which reflects they have a 85% chance of winning this college game. Florida State are the underdogs at +400 and they’re regarded as least likely to win.

9.5 is where the spread lies, with total points being 143.5 right now. A Total bet is always available and can often provide value selections. The Over 143.5 selection is available to back at -118.

The good news is that you can access a wide range of team props and game lines for most college basketball contests. The best betting apps have a huge range of pre-game and in-game wagering options.

Moneyline

FSU

+400

Clemson

-556

Point Spread

FSU +9.5

-110

Clemson -9.5

-110

Total Points

Under 143.5

-104

Over 143.5

-118

The best gambling sites offer player prop betting to their customers. These can be a great alternative if you want to focus on an individual’s performance within a game and it often involves wagering over or under a line.

It’s possible to use stats to your advantage when it comes to college basketball micro betting, especially if you’re predicting outcomes such as the Next Field Goal. Check out the live player, score and team props to see if you can find an angle.

Latest regular season and playoff games stats.

Florida State Stats

Clemson Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +9.5 Betting Line: Have covered the spread in the last 10 games
• +9.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• -9.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -9.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 149.30 pts in the previous 10 games
• Game Totals on the Road: An average of 152.40 pts in the previous 10 games on the road
• Over 143.5: Covered in 6 of the previous 10 games
• Over 143.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 76.20 pts and allowed 73.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 74.00 pts and allowed 78.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 135.00 pts in the previous 10 games
• Game Totals at Home: An average of 135.20 pts in the previous 10 home games
• Over 143.5: Covered in 2 of the previous 10 games
• Over 143.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 69.90 pts and allowed 65.10 pts in the last 10 games
• Team Totals at Home: Have scored an average of 72.00 pts and allowed 63.20 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	24-2	2157	1642	515	15-0	9-2	3W
Virginia	23-3	2129	1753	376	13-1	10-2	7W
Miami	21-5	2156	1818	338	14-3	7-2	4W
North Carolina	20-6	2103	1843	260	16-0	4-6	1L
Clemson	20-7	2022	1767	255	13-2	7-5	3L
Louisville	19-7	2257	1868	389	13-2	6-5	1L
NC State	19-8	2291	1992	299	12-5	7-3	1W
SMU	18-8	2250	2024	226	15-2	3-6	1W
California	18-8	2053	1897	156	15-3	3-5	1W
Virginia Tech	17-10	2124	2010	114	13-3	4-7	2L
Stanford	16-10	1961	1886	75	10-6	6-4	1L
Syracuse	15-12	2053	1977	76	12-4	3-8	1L
Wake Forest	14-12	2077	2002	75	10-6	4-6	3W
Florida State	13-13	2089	2032	57	10-7	3-6	2W
Notre Dame	12-14	1941	1909	32	10-5	2-9	1W
Georgia Tech	11-16	2005	2078	-73	10-8	1-8	8L
Pittsburgh	9-17	1818	1866	-48	7-9	2-8	5L
Boston College	9-17	1758	1813	-55	8-10	1-7	7L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

Top Basketball Pages