Lafayette vs Penn Prediction, Picks & Odds | 08 Dec 2025

College Basketball Betting Preview: Lafayette vs Penn

The Lafayette Leopards face the Penn Quakers, with tip-off scheduled for 18:00 on Monday, December 8.

Penn are available at odds of -120 when it comes to backing them against the spread. The appealing -5.5 line could be covered with ease when they play Lafayette and this looks like a value bet.

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Lafayette Leopards previous game saw them claim a 79-71 home win over Mercyhurst Lakers.

Penn Quakers lost when they last took to the court. They were turned over 77-60 at home to Hofstra Pride.

Head-to-Head Statistics

The last matchup between Lafayette and Penn saw the former win. It was a 65-63 scoreline. Penn have won four of the previous 6 H2H meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Penn	5-4	718	707	11	4-1	1-3	2L
Lafayette	3-7	693	750	-57	3-3	0-4	1W

View Full Standings

Lafayette vs Penn Prediction & Picks

This Lafayette vs Penn betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.

Game Prediction

Our best wager is that Penn are going to cover a generous -5.5 on the spread. You can get -120 that there’s a bigger margin of victory in this college contest.

We keep a close eye on team news and our college basketball handicappers stay sharp by tracking the latest form and lineups. You’ll also find a full set of stats that offer valuable insight and help shape smarter predictions ahead of the action.

Key Lafayette vs Penn stats:

• The -5.5 line has been covered by Penn in 3 of their last 5 games at home.
• The +5.5 line hasn’t been covered by Lafayette in 6 of their last 10 games.
• The +5.5 line hasn’t been covered by Lafayette in 3 of their last 5 games on the road.

Penn -5.5 Probability

When you look at the latest odds, our pick has a 54.6% chance of landing a return. After careful examination, our analysts calculate this probability to be closer to 60%. It is therefore regarded as a value bet.

If the price on display doesn’t appeal, you can make the choice to secure bigger odds by moving the line for your selection. It’s a case of taking a view which you are happy with.

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Our Game Prediction

Penn -5.5 @ -120 Bet Now

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Correct Score Prediction

Lafayette 70 - 78 Penn

For those wanting a big return from a small stake, consider the correct score lines. For example, the Quakers can be backed to win 78-70 at huge betting odds.

Lafayette vs Penn Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

With a 75% chance of securing victory, Penn are favorites for this college game and the sportsbooks have them at betting odds of -294. The market suggests that Lafayette are least likely to win at +235.

The spread is 5.5 and the total points line is currently 152.5. There is no denying the popularity of betting on the Totals. If you want to bet Under 152.5, there are odds of -105.

College basketball fans are spoiled for choice with the wide range of team props and game lines available for every matchup on the schedule. Visit the top sportsbooks to find the best value picks.

Moneyline

Lafayette

+235

Penn

-294

Point Spread

Lafayette +5.5

-102

Penn -5.5

-120

Total Points

Under 152.5

-105

Over 152.5

-115

You shouldn’t overlook the player props when it comes to betting on individual games. Many gambling sites will give you the chance to get with or bet against a specific player when it comes to number of Points, Assists, Steals and Blocks.

Instead of focusing on the overall outcome, some bettors prefer to look at the college basketball micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include Next Field Goal, with the options being for a two-pointer or a three-pointer.

Latest regular season and playoff games stats.

Lafayette Stats

Penn Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• +5.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +5.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -5.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -5.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 144.30 pts in the previous 10 games
• Game Totals on the Road: An average of 140.30 pts in the previous 10 games on the road
• Over 152.5: Covered in 4 of the previous 10 games
• Over 152.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 69.30 pts and allowed 75.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 64.80 pts and allowed 75.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 159.10 pts in the previous 10 games
• Game Totals at Home: An average of 152.90 pts in the previous 10 home games
• Over 152.5: Covered in 6 of the previous 10 games
• Over 152.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 78.90 pts and allowed 80.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 77.70 pts and allowed 75.20 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Ivy League	Overall	PF	PA	N. Pts	Home	Away	Strk
Yale	10-1	954	771	183	5-1	5-0	7W
Columbia	9-1	813	656	157	6-0	3-1	8W
Penn	5-4	718	707	11	4-1	1-3	2L
Cornell	5-5	911	858	53	3-0	2-5	3L
Harvard	5-6	766	750	16	3-1	2-5	2L
Dartmouth	3-4	557	532	25	2-2	1-2	1L
Brown	4-6	656	664	-8	2-3	2-3	1W
Princeton	3-9	835	890	-55	3-2	0-7	6L

Patriot League	Overall	PF	PA	N. Pts	Home	Away	Strk
American	7-4	898	775	123	7-1	0-3	3W
Colgate	5-4	681	658	23	3-1	2-3	3W
Navy	6-5	792	761	31	3-2	3-3	2W
Loyola Maryland	4-6	763	749	14	4-2	0-4	1L
Boston University	4-6	759	762	-3	3-1	1-5	1L
Army	4-7	808	855	-47	3-4	1-3	1W
Holy Cross	4-7	734	828	-94	2-1	2-6	2W
Lafayette	3-7	693	750	-57	3-3	0-4	1W
Lehigh	3-8	769	815	-46	2-2	1-6	2L
Bucknell	2-9	742	884	-142	1-4	1-5	9L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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