Lafayette vs Penn Prediction, Picks & Odds | 08 Dec 2025

College Basketball Betting Preview: Lafayette vs Penn

The Lafayette Leopards face the Penn Quakers, with tip-off scheduled for 18:00 on Monday, December 8.

Penn are available at odds of -120 when it comes to backing them against the spread. The appealing -5.5 line could be covered with ease when they play Lafayette and this looks like a value bet.

Lafayette Leopards previous game saw them claim a 79-71 home win over Mercyhurst Lakers.

Penn Quakers lost when they last took to the court. They were turned over 77-60 at home to Hofstra Pride.

Head-to-Head Statistics

The last matchup between Lafayette and Penn saw the former win. It was a 65-63 scoreline. Penn have won four of the previous 6 H2H meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Penn	15-11	1975	1921	54	12-2	3-9	2W
Lafayette	11-20	2145	2299	-154	6-9	5-11	2W

View Full Standings

Lafayette vs Penn Prediction & Picks

This Lafayette vs Penn betting breakdown features a main match prediction, a correct score insight and a sharply constructed bet builder to guide your wagers.

Game Prediction

Our best wager is that Penn are going to cover a generous -5.5 on the spread. You can get -120 that there’s a bigger margin of victory in this college contest.

We keep a close eye on team news and our college basketball handicappers stay sharp by tracking the latest form and lineups. You’ll also find a full set of stats that offer valuable insight and help shape smarter predictions ahead of the action.

Key Lafayette vs Penn stats:

• The -5.5 line has been covered by Penn in 3 of their last 5 games at home.
• The +5.5 line hasn’t been covered by Lafayette in 6 of their last 10 games.
• The +5.5 line hasn’t been covered by Lafayette in 3 of their last 5 games on the road.

Penn -5.5 Probability

When you look at the latest odds, our pick has a 54.6% chance of landing a return. After careful examination, our analysts calculate this probability to be closer to 60%. It is therefore regarded as a value bet.

If the price on display doesn’t appeal, you can make the choice to secure bigger odds by moving the line for your selection. It’s a case of taking a view which you are happy with.

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Our Game Prediction

Penn -5.5 @ -120 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Dec 7, 22:55). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Lafayette 70 - 78 Penn

For those wanting a big return from a small stake, consider the correct score lines. For example, the Quakers can be backed to win 78-70 at huge betting odds.

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Lafayette vs Penn Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

With a 77% chance of securing victory, Penn are favorites for this college game and the sportsbooks have them at betting odds of -333. The market suggests that Lafayette are least likely to win at +260.

The spread is 6.5 and the total points line is currently 151.5. There is no denying the popularity of betting on the Totals. If you want to bet Under 151.5, there are odds of -105.

College basketball fans are spoiled for choice with the wide range of team props and game lines available for every matchup on the schedule. Visit the top sportsbooks to find the best value picks.

Moneyline

Lafayette

+260

Penn

-333

Point Spread

Lafayette +6.5

-108

Penn -6.5

-112

Total Points

Under 151.5

-105

Over 151.5

-115

You shouldn’t overlook the player props when it comes to betting on individual games. Many gambling sites will give you the chance to get with or bet against a specific player when it comes to number of Points, Assists, Steals and Blocks.

Instead of focusing on the overall outcome, some bettors prefer to look at the college basketball micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include Next Field Goal, with the options being for a two-pointer or a three-pointer.

Latest regular season and playoff games stats.

Lafayette Stats

Penn Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• +5.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +5.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -5.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -5.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 144.30 pts in the previous 10 games
• Game Totals on the Road: An average of 140.30 pts in the previous 10 games on the road
• Over 152.5: Covered in 4 of the previous 10 games
• Over 152.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 69.30 pts and allowed 75.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 64.80 pts and allowed 75.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 159.10 pts in the previous 10 games
• Game Totals at Home: An average of 152.90 pts in the previous 10 home games
• Over 152.5: Covered in 6 of the previous 10 games
• Over 152.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 78.90 pts and allowed 80.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 77.70 pts and allowed 75.20 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Ivy League	Overall	PF	PA	N. Pts	Home	Away	Strk
Yale	22-5	2203	1912	291	11-2	11-3	1W
Harvard	16-11	1891	1801	90	7-4	9-7	1L
Columbia	16-11	2075	1926	149	9-5	7-6	1L
Penn	15-11	1975	1921	54	12-2	3-9	2W
Cornell	14-12	2290	2157	133	7-4	7-8	2W
Dartmouth	11-15	1957	1960	-3	5-7	6-8	2L
Princeton	9-19	1936	2009	-73	8-6	1-13	1W
Brown	8-17	1724	1776	-52	5-7	3-10	2L

Patriot League	Overall	PF	PA	N. Pts	Home	Away	Strk
Navy	25-6	2319	1963	356	14-2	11-4	13W
Colgate	16-14	2269	2259	10	9-5	7-9	2L
American	16-15	2314	2208	106	11-6	5-9	2L
Lehigh	15-16	2271	2320	-49	10-4	5-12	3W
Boston University	15-16	2358	2295	63	10-5	5-11	2W
Loyola Maryland	12-19	2330	2376	-46	8-7	4-12	1W
Lafayette	11-20	2145	2299	-154	6-9	5-11	2W
Army	11-20	2254	2406	-152	6-11	5-9	3L
Holy Cross	10-22	2162	2364	-202	6-8	4-14	2L
Bucknell	9-22	2089	2389	-300	5-9	4-13	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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