Louisville vs Notre Dame Prediction, Picks & Odds | 16 Feb 2025

Louisville should enjoy a comfortable victory and a wager against the spread could be the best way forward. Back our pick off -6.5 to cover the line in their meeting with Notre Dame at -110.

Louisville Cardinals won their previous game 91-66. This was a road victory against NC State Wolfpack.

Notre Dame Fighting Irish won last time out by a 97-94 (OT) scoreline. It was on the road against Boston College Eagles.

Head-to-Head Statistics

Notre Dame beat Louisville in their last head-to-head matchup. It was a 72-50 scoreline. Notre Dame have four consecutive wins against Louisville. However, they have lost 5 of the 9 previous head-to-head matchups.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Louisville	9-1	943	681	262	7-0	2-1	2W
Notre Dame	9-3	928	817	111	8-0	1-3	4W

View Full Standings

Louisville vs Notre Dame Prediction & Picks

It’s great to see the favorites given a -6.5 line on the spread at odds of -110 as we’re expecting a bigger margin of victory in this college matchup.

The expert college basketball handicappers at Sportsgambler.com check injury updates regularly and combine this with the form guide. We’re also able to consult a database of stats and present the key numbers to our readers.

Key Louisville vs Notre Dame stats:

• The -6.5 line has been covered by Louisville in 8 of their last 10 games.
• The -6.5 line has been covered by Louisville in 4 of their last 5 games.
• The -6.5 line has been covered by Louisville in 3 consecutive games.

Louisville -6.5 Probability

According to the sportsbooks, our pick has a 52.4% chance of winning. After careful examination, our analysts calculate this probability to be closer to 60%. It is the reason why we are recommending this college basketball wager.

Want bigger odds when it comes to your bet? Never fear, you are able to head to the sportsbooks and move the line until you’re happy with the price.

Our Game Prediction

Louisville -6.5 @ -110 Bet Now

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Player Prop Picks

Top Pick: Tae Davis Under 14.5 Points -108

Tae Davis (Notre Dame) can be wagered to total Under 14.5 points at -108. We’re expecting him to fall short of the Player Points line which makes an Unders bet really appealing.

Latest Tae Davis Player Prop Odds

Points

Over 14.5

-119

Under 14.5

-109

Assists

Over 1.5

-182

Under 1.5

+139

Rebounds

Over 5.5

-122

Under 5.5

-106

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J'Vonne Hadley Over 12.5 Points -120

J'Vonne Hadley (Louisville) can be backed to score Over 12.5 points at -120. He should be capable of going over the total which looks attractive when it comes to having a bet on Player Points.

Latest J'Vonne Hadley Player Prop Odds

Points

Over 12.5

-116

Under 12.5

-111

Assists

Over 1.5

-167

Under 1.5

+127

Rebounds

Over 6.5

+118

Under 6.5

-154

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Correct Score Prediction

Louisville 79 - 70 Notre Dame

If you want to take a chance on a correct score, then Louisville to enjoy a 79-70 win could be along the right lines. There are enormous odds for this particular outcome.

Louisville vs Notre Dame Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

For this college game, the sportsbooks’ Moneyline betting odds mean Louisville are -323 favorites to win and that means a 76% chance of landing a victory. For those wanting to back Notre Dame, you will find +255 about the underdogs.

The spread is 7.5 and the total points line is currently 146.5. The Totals offers basketball fans an alternative way of getting involved. There’s an opportunity to bet Over 146.5 at -110.

Louisville can be backed in lots of ways and that includes Race to 20 Points where they are -210 favorites. Notre Dame are +155 should you think they’ll make this total first instead.

If you’re planning to place a bet on a college basketball contest, visit the betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

Louisville

-323

Notre Dame

+255

Point Spread

Louisville -7.5

-112

Notre Dame +7.5

-108

Total Points

Under 146.5

-110

Over 146.5

-110

In terms of scoring most points, favorite Markus Burton is available at -114 to rack up Over 19.5 points. If you want to go Under, then the same odds are available.

Markus Burton (Notre Dame)

Over 19.5

-114

Under 19.5

-114

Terrence Edwards Jr. (Louisville)

Over 15.5

-110

Under 15.5

-118

Tae Davis (Notre Dame)

Over 14.5

-119

Under 14.5

-109

Chucky Hepburn (Louisville)

Over 14.5

-108

Under 14.5

-120

Reyne Smith (Louisville)

Over 14.5

-102

Under 14.5

-127

J'Vonne Hadley (Louisville)

Over 12.5

-116

Under 12.5

-111

Braeden Shrewsberry (Notre Dame)

Over 11.5

-102

Under 11.5

-127

Chucky Hepburn (Louisville)

Over 6.5

+110

Under 6.5

-143

Terrence Edwards Jr. (Louisville)

Over 3.5

+117

Under 3.5

-152

Markus Burton (Notre Dame)

Over 2.5

-114

Under 2.5

-114

Tae Davis (Notre Dame)

Over 1.5

-182

Under 1.5

+139

J'Vonne Hadley (Louisville)

Over 1.5

-167

Under 1.5

+127

Braeden Shrewsberry (Notre Dame)

Over 1.5

+124

Under 1.5

-161

J'Vonne Hadley (Louisville)

Over 6.5

+118

Under 6.5

-154

Tae Davis (Notre Dame)

Over 5.5

-122

Under 5.5

-106

Terrence Edwards Jr. (Louisville)

Over 4.5

+107

Under 4.5

-139

Markus Burton (Notre Dame)

Over 3.5

+107

Under 3.5

-139

Chucky Hepburn (Louisville)

Over 3.5

-110

Under 3.5

-118

Reyne Smith (Louisville)

Over 2.5

-182

Under 2.5

+138

Braeden Shrewsberry (Notre Dame)

Over 2.5

-161

Under 2.5

+123

Latest regular season and playoff games stats.

Louisville Stats

Notre Dame Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 8 wins and 2 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• -6.5 Betting Line: Have covered the spread in 8 of the last 10 games
• -6.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road

Point Spread

• +6.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +6.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 150.60 pts in the previous 10 games
• Game Totals on the Road: An average of 153.60 pts in the previous 10 games on the road
• Over 145.5: Covered in 7 of the previous 10 games
• Over 145.5 on the Road: Covered in 8 of the previous 10 games on the road
• Team Totals: Have scored an average of 82.50 pts and allowed 68.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 83.40 pts and allowed 70.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 141.70 pts in the previous 10 games
• Game Totals at Home: An average of 146.60 pts in the previous 10 home games
• Over 145.5: Covered in 3 of the previous 10 games
• Over 145.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 71.20 pts and allowed 70.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 75.90 pts and allowed 70.70 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	10-0	868	596	272	7-0	3-0	10W
California	10-1	909	761	148	10-0	0-1	7W
Louisville	9-1	943	681	262	7-0	2-1	2W
Virginia	9-1	871	675	196	7-0	2-1	4W
North Carolina	9-1	811	647	164	8-0	1-1	3W
Miami	9-2	960	732	228	7-1	2-1	4W
SMU	9-2	975	849	126	8-0	1-2	1L
Virginia Tech	9-2	916	810	106	7-0	2-2	3W
Stanford	8-2	823	732	91	5-2	3-0	1W
Notre Dame	9-3	928	817	111	8-0	1-3	4W
Clemson	8-3	900	730	170	7-0	1-3	1W
Wake Forest	7-3	842	727	115	5-1	2-2	1W
NC State	7-4	964	804	160	6-2	1-2	1L
Syracuse	6-4	726	650	76	5-1	1-3	1L
Georgia Tech	6-4	724	692	32	6-2	0-2	1W
Florida State	5-5	853	809	44	5-3	0-2	4L
Boston College	5-6	774	742	32	4-5	1-1	1L
Pittsburgh	5-6	779	772	7	5-3	0-3	3L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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