Loyola Chicago vs Saint Joseph's Prediction, Picks & Odds | 21 Feb 2026

College Basketball Betting Preview: Loyola Chicago vs Saint Joseph's

The Loyola Chicago Ramblers battle the Saint Joseph's Hawks, with tip-off scheduled for 12:00 on Saturday, February 21.

There’s a generous line of -9.5 when it comes to Saint Joseph's in their meeting with Loyola Chicago. The -120 that they cover the spread has plenty of juice and our prediction is it will happen.

Loyola Chicago Ramblers were beaten in their previous game and this was on the road. Fordham Rams claimed a 62-59 win.

Saint Joseph's Hawks triumphed in their last game. It was on the road where St. Bonaventure Bonnies were beaten 71-65.

Head-to-Head Statistics

The last head-to-head saw Saint Joseph's claim a 85-64 win over Loyola Chicago. The past 10 clashes between these teams have seen six Saint Joseph's wins.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Joseph's	16-10	1910	1849	61	12-3	4-7	1W
Loyola Chicago	6-21	1807	2087	-280	4-12	2-9	3L

View Full Standings

Loyola Chicago vs Saint Joseph's Prediction & Picks

Gear up for Loyola Chicago vs Saint Joseph's with our betting guide, featuring an expert match prediction, scoreline advice and a hand-picked bet builder. Explore each section below for detailed insights.

Game Prediction

Our pick is for Saint Joseph's to cover the attractive -9.5 line in this college showdown. The favorites should be able to triumph by a more comfortable margin and -120 is available.

Injuries are always factored in by the handicappers at Sportsgambler.com. Our basketball predictions are also shaped by recent form, with up-to-date college hoops stats playing a key role before any selections are locked in.

Key Loyola Chicago vs Saint Joseph's stats:

• The +9.5 line hasn’t been covered by Loyola Chicago in 4 of their last 5 games on the road.
• The +9.5 line hasn’t been covered by Loyola Chicago in 7 of their last 10 games.

Saint Joseph's -9.5 Probability

According to the latest odds, our pick has a 54.6% chance of delivering a return. After careful examination, our team calculate this probability to be closer to 60%. The wager can be recommended for this precise reason.

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Our Game Prediction

Saint Joseph's -9.5 @ -120 Bet Now

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Correct Score Prediction

Loyola Chicago 67 - 80 Saint Joseph's

A 80-67 win for Saint Joseph's is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a huge potential return.

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Loyola Chicago vs Saint Joseph's Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

You might not get rich backing Saint Joseph's at -625. However, the sportsbooks’ betting odds imply a 86% chance of winning this college game. For those wanting to oppose the market leader, you can get +450 about Loyola Chicago.

The spread currently stands at 9.5 and the total points line is 144.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. The Over 144.5 selection is available to back at -110.

College basketball bettors are spoilt for choice thanks to the huge selection of game lines and team props which are available for most matchups on the coupon. Head to the top betting apps and find the best value picks.

Moneyline

Loyola Chicago

+450

Saint Joseph's

-625

Point Spread

Loyola Chicago +9.5

-102

Saint Joseph's -9.5

-120

Total Points

Under 144.5

-110

Over 144.5

-110

The best gambling sites offer player prop betting to their customers. These can be a great alternative if you want to focus on an individual’s performance within a game and it often involves wagering over or under a line.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Latest regular season and playoff games stats.

Loyola Chicago Stats

Saint Joseph's Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +9.5 Betting Line: Have covered the spread in 3 of the last 10 games
• +9.5 Betting Line on the Road: Have covered the spread in 3 of the last 10 games on the road

Point Spread

• -9.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -9.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 142.80 pts in the previous 10 games
• Game Totals on the Road: An average of 142.90 pts in the previous 10 games on the road
• Over 141.5: Covered in 6 of the previous 10 games
• Over 141.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 64.60 pts and allowed 78.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 64.80 pts and allowed 78.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 137.30 pts in the previous 10 games
• Game Totals at Home: An average of 142.50 pts in the previous 10 home games
• Over 141.5: Covered in 4 of the previous 10 games
• Over 141.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 70.30 pts and allowed 67.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 74.50 pts and allowed 68.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	25-2	2433	1839	594	18-1	7-1	1W
George Mason	21-6	2005	1831	174	15-2	6-4	3L
VCU	21-7	2335	2048	287	14-3	7-4	1L
Dayton	17-9	1978	1852	126	13-3	4-6	2W
Duquesne	16-10	2122	1972	150	11-6	5-4	5W
Saint Joseph's	16-10	1910	1849	61	12-3	4-7	1W
Davidson	16-10	1913	1780	133	10-7	6-3	1W
Rhode Island	15-11	1885	1788	97	9-6	6-5	1W
George Washington	15-12	2238	1988	250	12-4	3-8	1L
Fordham	15-12	1902	1752	150	10-7	5-5	3W
St. Bonaventure	14-12	1980	1922	58	9-6	5-6	2L
Richmond	14-13	2086	1984	102	10-6	4-7	2L
La Salle	7-19	1705	1878	-173	5-7	2-12	6L
Loyola Chicago	6-21	1807	2087	-280	4-12	2-9	3L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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