Loyola Chicago vs Santa Clara Prediction, Picks & Odds | 20 Dec 2025

College Basketball Betting Preview: Loyola Chicago vs Santa Clara

The Loyola Chicago Ramblers square off against the Santa Clara Broncos, with tip-off scheduled for 17:00 on Saturday, December 20.

Play the Unders at -110 when Loyola Chicago and Santa Clara take to the court. The 151.5 points line looks plenty big enough and we’re not sure the pair will combine to get this total.

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Loyola Chicago Ramblers were beaten in their previous game and this was on the road. San Francisco Dons claimed a 85-71 win.

Santa Clara Broncos were winners last time out. It was a 63-60 home victory against North Texas Mean Green.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Santa Clara	9-3	950	835	115	7-1	2-2	1W
Loyola Chicago	3-9	822	920	-98	3-6	0-3	2L

View Full Standings

Loyola Chicago vs Santa Clara Prediction & Picks

Discover our expert Loyola Chicago vs Santa Clara betting tips, featuring a match prediction, correct score suggestion and bet builder advice. Scroll down for full analysis.

Game Prediction

The Unders looks the way to go for this college matchup. The line looks too high at 151.5 and odds of -110 could favor bettors who go below that total.

Sportsgambler.com brings strong college hoops expertise, built on knowing the team news as soon as it’s confirmed. Recent form plays a big part in our basketball picks and we always back it up with the most relevant stats.

Key Loyola Chicago vs Santa Clara stats:

• The 151.5 line hasn’t been covered in 13 of the last 20 Loyola Chicago games on the road.
• The 151.5 line hasn’t been covered in 6 of the last 10 Loyola Chicago games.
• The 151.5 line hasn’t been covered in 3 of the last 5 Santa Clara games at home.

Under 151.5 Probability

According to the latest betting odds, our pick has a 52.4% chance of winning. Taking all factors into consideration, our cappers think there’s a stronger chance of success and estimate the probability to be closer to 60%. This is why we can recommend this college basketball bet.

More juice from your Unders wager can be found by combining this selection on the Match Result & Total lines. Choose the odds which match your prediction.

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Our Game Prediction

Under 151.5 Points @ -110 Bet Now

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Correct Score Prediction

Loyola Chicago 64 - 84 Santa Clara

There are stacks of correct score lines on offer and we’re looking at Santa Clara to achieve a winning scoreline of 84-64 where a huge potential return is on the cards.

Loyola Chicago vs Santa Clara Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

You might not get rich backing Santa Clara at -2000. However, the sportsbooks’ betting odds imply a 95% chance of winning this college game. Loyola Chicago are regarded as a long shot to win and you can currently back them at +980.

There is a spread of 15.5 and total points has a line of 151.5. A bet on the Totals allows fans to use the latest basketball data to good effect. There’s the chance to back Under 151.5 at -110.

There are stacks of game lines and team props s when it comes to wagering on college basketball and we recommend visiting the top betting apps to find the bet that matches your view on the contest.

Moneyline

Loyola Chicago

+980

Santa Clara

-2000

Point Spread

Loyola Chicago +15.5

-115

Santa Clara -15.5

-105

Total Points

Under 151.5

-110

Over 151.5

-110

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

There are some exciting college basketball micro betting lines that are created and they are available in-game. Among them are Next Field Goal, where you select if the shot will be a two or three-pointer. The long-ball option pays better, and in today’s game, you can never discount the three-pointer.

Latest regular season and playoff games stats.

Loyola Chicago Stats

Santa Clara Stats

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +15.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +15.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -15.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -15.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 142.50 pts in the previous 10 games
• Game Totals on the Road: An average of 144.10 pts in the previous 10 games on the road
• Over 151.5: Covered in 4 of the previous 10 games
• Over 151.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 66.60 pts and allowed 75.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 69.20 pts and allowed 74.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 150.30 pts in the previous 10 games
• Game Totals at Home: An average of 149.40 pts in the previous 10 home games
• Over 151.5: Covered in 6 of the previous 10 games
• Over 151.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 78.80 pts and allowed 71.50 pts in the last 10 games
• Team Totals at Home: Have scored an average of 82.10 pts and allowed 67.30 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

West Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Gonzaga	11-1	1109	795	314	8-0	3-1	4W
Saint Mary's	10-2	965	778	187	8-0	2-2	1W
Seattle	10-2	982	797	185	8-2	2-0	5W
Santa Clara	9-3	950	835	115	7-1	2-2	1W
Loyola Marymount	8-4	945	803	142	5-4	3-0	1W
Pacific	8-4	897	795	102	5-0	3-4	1L
San Francisco	7-5	906	835	71	5-1	2-4	1W
Portland	6-5	897	899	-2	6-2	0-3	1L
Oregon State	6-6	874	871	3	6-5	0-1	1L
San Diego	5-6	826	838	-12	4-3	1-3	2W
Pepperdine	4-8	884	898	-14	3-4	1-4	1L
Washington State	4-8	906	927	-21	3-4	1-4	1W

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	10-1	1021	754	267	9-1	1-0	4W
George Mason	10-1	874	714	160	8-0	2-1	1W
St. Bonaventure	11-2	1019	906	113	8-0	3-2	1W
Richmond	9-2	926	784	142	7-0	2-2	1L
Davidson	8-3	827	739	88	6-3	2-0	1L
Dayton	9-4	1035	914	121	8-2	1-2	1L
Fordham	8-4	916	750	166	7-2	1-2	2W
VCU	8-4	1026	860	166	7-2	1-2	2W
George Washington	8-4	1042	907	135	6-2	2-2	2L
Rhode Island	8-4	892	798	94	5-2	3-2	1W
Saint Joseph's	6-4	756	723	33	6-0	0-4	1W
Duquesne	6-5	920	884	36	6-2	0-3	2L
La Salle	3-8	743	764	-21	3-3	0-5	5L
Loyola Chicago	3-9	822	920	-98	3-6	0-3	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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