Memphis vs Louisville Prediction, Picks & Odds | 13 Dec 2025

College Basketball Betting Preview: Memphis vs Louisville

The Memphis Tigers face the Louisville Cardinals, with tip-off scheduled for 16:30 on Saturday, December 13.

We have decided to go for Louisville against the spread in order to get the best value. They should be able to cover an appealing -16.5 line at -110 when they take on Memphis.

Memphis Tigers won their previous game which was at home. It was a 78-71 triumph against Baylor Bears.

Louisville Cardinals won last time out by a 87-78 scoreline. It was on the road against Indiana Hoosiers.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Louisville	22-9	2662	2246	416	15-2	7-7	2W
Memphis	13-18	2338	2373	-35	10-7	3-11	1W

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Memphis vs Louisville Prediction & Picks

We cover the key Memphis vs Louisville betting angles, showcasing our expert match prediction, best correct score selection, top player props and a bet builder tailored for value.

Game Prediction

We’re predicting that Louisville will be superior in this college game and that’s why we’re backing them on the spread at -16.5. Take the -110 that the big favorites are able to cover this line.

To deliver the best possible basketball picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date college hoops stats available.

Key Memphis vs Louisville stats:

• The -16.5 line has been covered by Louisville in 4 of their last 5 games at home.
• The -16.5 line has been covered by Louisville in 6 of their last 10 games at home.
• The -16.5 line has been covered by Louisville in 3 consecutive games at home.

Louisville -16.5 Probability

The top betting apps imply that our pick has a 52.4% prospect of delivering a return. However, we think that the probability sits between 55-60% taking all factors into consideration. This is why we can recommend this college basketball wager.

Want bigger odds when it comes to your wager? Never fear, you are able to head to the sportsbooks and move the line until you’re happy with the price.

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Our Game Prediction

Louisville -16.5 @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Dec 12, 20:56). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Mikel Brown Jr. Under 4.5 Assists -100

Mikel Brown Jr. (Louisville) can be wagered to record Under 4.5 assists at -100. There’s no reason to oppose our instinct, so we’ll bet on him failing to cover the Player Assists total here.

Latest Mikel Brown Jr. Player Prop Odds

Points

Over 15.5

-123

Under 15.5

-104

Assists

Over 4.5

-111

Under 4.5

-116

Rebounds

Over 3.5

-164

Under 3.5

+125

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J'Vonne Hadley Over 5.5 Rebounds -154

J'Vonne Hadley (Louisville) can be backed to record Over 5.5 rebounds at -154. The best bet could be to go for a Player Rebounds wager as we think he’ll cover the total.

Latest J'Vonne Hadley Player Prop Odds

Points

Over 11.5

-100

Under 11.5

-130

Assists

Over 1.5

-120

Under 1.5

-110

Rebounds

Over 5.5

-154

Under 5.5

+120

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Memphis 72 - 91 Louisville

A 91-72 win for Louisville is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a huge potential return.

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Memphis vs Louisville Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Louisville have short betting odds and they’re overwhelming -2000 favorites for this college game. This means the sportsbooks give them a 95% chance of winning. For those wanting to oppose the market leader, you can get +1000 about Memphis.

The spread is calculated to be 15.5, while total points comes in at 160.5. The Totals offers basketball fans an alternative way of getting involved. The Over 160.5 selection is available to back at -110.

College hoops fans are spoilt for choice thanks to the wide range of team props and game lines which are available for every contest on the coupon. Head to the top basketball sportsbooks and find the best value picks.

Moneyline

Memphis

+1000

Louisville

-2000

Point Spread

Memphis +15.5

-110

Louisville -15.5

-110

Total Points

Under 160.5

-110

Over 160.5

-110

Ryan Conwell is favorite when it comes to getting the most points. You can get -119 that he goes Over 20.5 points and -109 when it comes to Under.

Ryan Conwell (Louisville)

Over 20.5

-119

Under 20.5

-109

Mikel Brown Jr. (Louisville)

Over 15.5

-123

Under 15.5

-104

Dug McDaniel (Memphis)

Over 14.5

-105

Under 14.5

-123

Isaac McKneely (Louisville)

Over 11.5

-110

Under 11.5

-118

J'Vonne Hadley (Louisville)

Over 11.5

-100

Under 11.5

-130

Sananda Fru (Louisville)

Over 10.5

-135

Under 10.5

-100

Dug McDaniel (Memphis)

Over 5.5

+109

Under 5.5

-141

Mikel Brown Jr. (Louisville)

Over 4.5

-111

Under 4.5

-116

Ryan Conwell (Louisville)

Over 2.5

-141

Under 2.5

+105

Isaac McKneely (Louisville)

Over 1.5

+180

Under 1.5

-233

J'Vonne Hadley (Louisville)

Over 1.5

-120

Under 1.5

-110

Sananda Fru (Louisville)

Over 0.5

-233

Under 0.5

+180

Sananda Fru (Louisville)

Over 7.5

+120

Under 7.5

-154

J'Vonne Hadley (Louisville)

Over 5.5

-154

Under 5.5

+120

Ryan Conwell (Louisville)

Over 4.5

-130

Under 4.5

-100

Mikel Brown Jr. (Louisville)

Over 3.5

-164

Under 3.5

+125

Isaac McKneely (Louisville)

Over 3.5

-115

Under 3.5

-115

Dug McDaniel (Memphis)

Over 2.5

-164

Under 2.5

+130

Micro betting provides a rollercoaster ride for college basketball bettors. It can be great to enjoy the live lines, with the opportunity to bet on the Next Field Goal. Watch the live action before deciding which way to go.

Latest regular season and playoff games stats.

Memphis Stats

Louisville Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +16.5 Betting Line: Have covered the spread in the last 10 games
• +16.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road

Point Spread

• -16.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -16.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 150.50 pts in the previous 10 games
• Game Totals on the Road: An average of 154.00 pts in the previous 10 games on the road
• Over 158.5: Covered in 2 of the previous 10 games
• Over 158.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 76.20 pts and allowed 74.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 78.20 pts and allowed 75.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 161.60 pts in the previous 10 games
• Game Totals at Home: An average of 155.70 pts in the previous 10 home games
• Over 158.5: Covered in 6 of the previous 10 games
• Over 158.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 91.90 pts and allowed 69.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 89.70 pts and allowed 66.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	29-2	2571	1937	634	18-0	11-2	8W
Virginia	27-4	2507	2116	391	17-1	10-3	2W
Miami	24-7	2564	2192	372	15-4	9-3	1L
North Carolina	24-7	2474	2202	272	19-0	5-7	1L
Clemson	22-9	2309	2055	254	15-3	7-6	1W
Louisville	22-9	2662	2246	416	15-2	7-7	2W
California	21-10	2403	2249	154	17-4	4-6	1L
Stanford	20-11	2368	2262	106	12-6	8-5	4W
NC State	19-12	2590	2356	234	12-7	7-5	4L
SMU	19-12	2635	2430	205	16-3	3-9	4L
Virginia Tech	19-12	2432	2301	131	15-3	4-9	1L
Florida State	17-14	2478	2403	75	11-8	6-6	3W
Wake Forest	16-15	2445	2383	62	12-6	4-9	1W
Syracuse	15-16	2331	2290	41	12-6	3-10	5L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	12-19	2175	2209	-34	8-10	4-9	1W
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

American Athletic Conference	Overall	PF	PA	N. Pts	Home	Away	Strk
Tulsa	25-6	2666	2244	422	14-2	11-4	5W
South Florida	23-8	2739	2373	366	14-4	9-4	9W
Wichita State	21-10	2426	2186	240	14-5	7-5	6W
UAB	20-11	2457	2278	179	9-9	11-2	2W
North Texas	18-13	2183	2065	118	12-5	6-8	2W
Florida Atlantic	17-14	2463	2320	143	11-6	6-8	1L
Tulane	17-14	2248	2350	-102	10-9	7-5	4L
Temple	16-15	2307	2201	106	10-7	6-8	1L
Charlotte	15-16	2271	2306	-35	11-7	4-9	3L
Memphis	13-18	2338	2373	-35	10-7	3-11	1W
Rice	13-18	2291	2311	-20	9-8	4-10	1W
East Carolina	11-20	2217	2401	-184	7-12	4-8	2L
UTSA	5-25	2084	2422	-338	2-12	3-13	5L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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