Memphis vs Louisville Prediction, Picks & Odds | 13 Dec 2025

College Basketball Betting Preview: Memphis vs Louisville

The Memphis Tigers face the Louisville Cardinals, with tip-off scheduled for 15:30 on Saturday, December 13.

We have decided to go for Louisville against the spread in order to get the best value. They should be able to cover an appealing -16.5 line at -110 when they take on Memphis.

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Memphis Tigers won their previous game which was at home. It was a 78-71 triumph against Baylor Bears.

Louisville Cardinals won last time out by a 87-78 scoreline. It was on the road against Indiana Hoosiers.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Louisville	8-1	844	608	236	6-0	2-1	1W
Memphis	4-4	608	593	15	4-2	0-2	3W

View Full Standings

Memphis vs Louisville Prediction & Picks

Get fully prepped for Memphis vs Louisville with our betting guide, featuring our expert match pick, predicted scoreline and a value-focused bet builder. Read on for the full breakdown.

Game Prediction

We’re predicting that Louisville will be superior in this college game and that’s why we’re backing them on the spread at -16.5. Take the -110 that the big favorites are able to cover this line.

To deliver the best possible basketball picks, we start by locking in the team news and taking time to review the latest form. There’s also no shortage of data to crunch from the most up-to-date college hoops stats available.

Key Memphis vs Louisville stats:

• The -16.5 line has been covered by Louisville in 4 of their last 5 games at home.
• The -16.5 line has been covered by Louisville in 6 of their last 10 games at home.
• The -16.5 line has been covered by Louisville in 3 consecutive games at home.

Louisville -16.5 Probability

The top betting apps imply that our pick has a 52.4% prospect of delivering a return. However, we think that the probability sits between 55-60% taking all factors into consideration. This is why we can recommend this college basketball wager.

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Our Game Prediction

Louisville -16.5 @ -110 Bet Now

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Correct Score Prediction

Memphis 72 - 91 Louisville

A 91-72 win for Louisville is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a huge potential return.

Memphis vs Louisville Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Louisville have short betting odds and they’re overwhelming -2500 favorites for this college game. This means the sportsbooks give them a 96% chance of winning. For those wanting to oppose the market leader, you can get +1060 about Memphis.

The spread is calculated to be 16.5, while total points comes in at 158.5. The Totals offers basketball fans an alternative way of getting involved. The Over 158.5 selection is available to back at -115.

College hoops fans are spoilt for choice thanks to the wide range of team props and game lines which are available for every contest on the coupon. Head to the top basketball sportsbooks and find the best value picks.

Moneyline

Memphis

+1060

Louisville

-2500

Point Spread

Memphis +16.5

-110

Louisville -16.5

-110

Total Points

Under 158.5

-105

Over 158.5

-115

Prop betting is very popular, with bettors looking to wager on player props such as Points, Assists, Rebounds, Steals and Three-Pointers. It’s a great way of betting on individual player performance and the gambling sites will provide lots of options.

Micro betting provides a rollercoaster ride for college basketball bettors. It can be great to enjoy the live lines, with the opportunity to bet on the Next Field Goal. Watch the live action before deciding which way to go.

Latest regular season and playoff games stats.

Memphis Stats

Louisville Stats

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +16.5 Betting Line: Have covered the spread in the last 10 games
• +16.5 Betting Line on the Road: Have covered the spread in the last 10 games on the road

Point Spread

• -16.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -16.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 150.50 pts in the previous 10 games
• Game Totals on the Road: An average of 154.00 pts in the previous 10 games on the road
• Over 158.5: Covered in 2 of the previous 10 games
• Over 158.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 76.20 pts and allowed 74.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 78.20 pts and allowed 75.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 161.60 pts in the previous 10 games
• Game Totals at Home: An average of 155.70 pts in the previous 10 home games
• Over 158.5: Covered in 6 of the previous 10 games
• Over 158.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 91.90 pts and allowed 69.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 89.70 pts and allowed 66.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	10-0	868	596	272	7-0	3-0	10W
Virginia	9-1	871	675	196	7-0	2-1	4W
California	9-1	830	691	139	9-0	0-1	6W
SMU	9-1	898	760	138	8-0	1-1	1W
Louisville	8-1	844	608	236	6-0	2-1	1W
North Carolina	8-1	731	585	146	7-0	1-1	2W
Virginia Tech	9-2	916	810	106	7-0	2-2	3W
Miami	8-2	856	653	203	6-1	2-1	3W
Stanford	7-2	737	650	87	5-2	2-0	1L
Notre Dame	8-3	846	759	87	7-0	1-3	3W
Clemson	7-3	830	667	163	6-0	1-3	2L
NC State	7-3	888	727	161	6-1	1-2	2W
Wake Forest	7-3	842	727	115	5-1	2-2	1W
Syracuse	6-3	657	580	77	5-0	1-3	2W
Georgia Tech	6-4	724	692	32	6-2	0-2	1W
Florida State	5-4	758	706	52	5-2	0-2	3L
Pittsburgh	5-5	718	693	25	5-3	0-2	2L
Boston College	5-6	774	742	32	4-5	1-1	1L

American Athletic Conference	Overall	PF	PA	N. Pts	Home	Away	Strk
Tulsa	9-1	907	697	210	6-0	3-1	6W
UAB	7-3	824	705	119	5-1	2-2	1W
Florida Atlantic	7-3	818	705	113	4-2	3-1	2W
North Texas	7-3	702	651	51	6-1	1-2	1L
Tulane	7-3	763	771	-8	5-3	2-0	1W
Wichita State	6-4	783	673	110	5-2	1-2	2W
South Florida	6-4	886	796	90	5-2	1-2	2W
Temple	5-4	714	667	47	4-2	1-2	1W
Memphis	4-4	608	593	15	4-2	0-2	3W
UTSA	4-5	653	640	13	2-2	2-3	2L
Rice	4-6	757	732	25	4-2	0-4	2W
Charlotte	4-6	701	717	-16	4-3	0-3	1L
East Carolina	3-7	674	769	-95	3-5	0-2	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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