Mercer vs Clemson Prediction, Picks & Odds | 13 Dec 2025

College Basketball Betting Preview: Mercer vs Clemson

The Mercer Bears battle the Clemson Tigers, with tip-off scheduled for 16:00 on Saturday, December 13.

We’re really sweet on the big favorites who are -21.5 on the spread. Clemson should enjoy a huge victory against Mercer and cover the line at -110.

Mercer Bears previous game saw them claim a 100-50 home win over Oglethorpe Stormy Petrels.

Clemson Tigers were beaten last game and this was on the road. Brigham Young Cougars claimed a 67-64 win.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Clemson	22-9	2309	2055	254	15-3	7-6	1W
Mercer	19-13	2646	2416	230	14-2	5-11	1L

View Full Standings

Mercer vs Clemson Prediction & Picks

Head into Mercer vs Clemson with expert betting insights, including our main match prediction, best correct score pick and a value-driven bet builder. Dive into each section below for more.

Game Prediction

There’s everything to like about the -21.5 line that Clemson have to cover in this college showdown. Take the -110 and feel confident that the favorites get the job done.

We closely track recent form and look for patterns that may impact the outcome. The same goes for injuries to key players. When combined with the most relevant college hoops stats, this gives us a strong foundation for accurate basketball picks.

Key Mercer vs Clemson stats:

• The -21.5 line has been covered by Clemson in 3 of their last 5 games at home.

Clemson -21.5 Probability

The best betting sites suggest there’s a 52.4% chance of our pick delivering a return. However, our cappers research has found that the actual probability is between 55-60%. It’s why we think it’s worth placing this college basketball wager.

If you want to pimp the odds about Clemson covering the line, you might consider going down the Bet Builder route and combine this prediction with other selections.

Take your betting up a notch with the latest promos, free bets and top betting offers inside our easy-to-use bonus guide.

Our Game Prediction

Clemson -21.5 @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Dec 12, 21:57). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Mercer 65 - 91 Clemson

Should you want a bet that can land a monster return, then look no further than the correct score lines. Back Clemson to win 91-65 and leverage a huge payout if this happens.

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Mercer vs Clemson Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Clemson are massive -10000 favorites. They are regarded as 99% likely to win this college game judging by the sportsbooks’ latest Moneyline odds. For those wanting to oppose the market leader, you can get +2400 about Mercer.

The current spread is 23.5 and total points is 149.5. There are many ways to bet on basketball including the Totals. If you want to back Over 149.5, it’s -104.

You can find a nice selection of game lines and team props for most college basketball matchups, with the top betting apps creating many different options. Check out the pre-game and in-game selections before placing your bets.

Moneyline

Mercer

+2400

Clemson

-10000

Point Spread

Mercer +23.5

-110

Clemson -23.5

-110

Total Points

Under 149.5

-118

Over 149.5

-104

The best gambling sites offer player prop betting to their customers. These can be a great alternative if you want to focus on an individual’s performance within a game and it often involves wagering over or under a line.

An increasing number of bettors are now enjoying micro betting on college basketball and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.

Latest regular season and playoff games stats.

Mercer Stats

Clemson Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +21.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +21.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -21.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -21.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 157.00 pts in the previous 10 games
• Game Totals on the Road: An average of 155.60 pts in the previous 10 games on the road
• Over 152.5: Covered in 5 of the previous 10 games
• Over 152.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 82.30 pts and allowed 74.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 73.20 pts and allowed 82.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 149.70 pts in the previous 10 games
• Game Totals at Home: An average of 135.80 pts in the previous 10 home games
• Over 152.5: Covered in 4 of the previous 10 games
• Over 152.5 at Home: Covered in 1 of the previous 10 home games
• Team Totals: Have scored an average of 83.00 pts and allowed 66.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 78.30 pts and allowed 57.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	29-2	2571	1937	634	18-0	11-2	8W
Virginia	27-4	2507	2116	391	17-1	10-3	2W
Miami	24-7	2564	2192	372	15-4	9-3	1L
North Carolina	24-7	2474	2202	272	19-0	5-7	1L
Clemson	22-9	2309	2055	254	15-3	7-6	1W
Louisville	22-9	2662	2246	416	15-2	7-7	2W
California	21-10	2403	2249	154	17-4	4-6	1L
Stanford	20-11	2368	2262	106	12-6	8-5	4W
NC State	19-12	2590	2356	234	12-7	7-5	4L
SMU	19-12	2635	2430	205	16-3	3-9	4L
Virginia Tech	19-12	2432	2301	131	15-3	4-9	1L
Florida State	17-14	2478	2403	75	11-8	6-6	3W
Wake Forest	16-15	2445	2383	62	12-6	4-9	1W
Syracuse	15-16	2331	2290	41	12-6	3-10	5L
Notre Dame	13-18	2308	2335	-27	11-7	2-11	2L
Pittsburgh	12-19	2175	2209	-34	8-10	4-9	1W
Boston College	11-20	2090	2191	-101	10-10	1-10	1W
Georgia Tech	11-20	2287	2400	-113	10-10	1-10	12L

Southern	Overall	PF	PA	N. Pts	Home	Away	Strk
E. Tennessee St.	23-11	2638	2356	282	15-5	8-6	1L
Furman	22-12	2600	2397	203	13-6	9-6	3W
Mercer	19-13	2646	2416	230	14-2	5-11	1L
Wofford	19-13	2520	2468	52	10-6	9-7	2L
Samford	18-14	2525	2409	116	11-4	7-10	1L
Western Carolina	15-16	2432	2397	35	10-3	5-13	1L
UNC Greensboro	15-19	2673	2736	-63	10-6	5-13	1L
Chattanooga	13-19	2454	2408	46	7-9	6-10	1L
Citadel	11-22	2322	2558	-236	7-9	4-13	1L
VMI	6-26	2303	2560	-257	5-9	1-17	17L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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