Mercyhurst vs Loyola Chicago Prediction, Picks & Odds | 06 Nov 2025

College Basketball Betting Preview: Mercyhurst vs Loyola Chicago

The Mercyhurst Lakers battle the Loyola Chicago Ramblers, with tip-off scheduled for 21:00 on Thursday, November 6. Our betting preview features expert NCAAB predictions, betting tips, the latest odds and H2H stats.

Side With Mercyhurst and Take a Big Line

There’s a lot to like about Mercyhurst +21.5 when they meet Loyola Chicago. You can get odds of -118 and we need the underdogs to avoid a sizeable defeat.

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Mercyhurst Well Beaten in Previous Clash

Mercyhurst Lakers were defeated in their previous game. On the road, they suffered a 70-47 reverse against Northwestern Wildcats.

Loyola Chicago Ramblers were winners last time out. It was a 91-88 home victory against Cleveland State Vikings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Loyola Chicago	1-0	91	88	3	1-0	0-0	1W
Mercyhurst	0-1	47	70	-23	0-0	0-1	1L

View Full Standings

Mercyhurst vs Loyola Chicago Prediction & Picks

Get ahead of the game with our Mercyhurst vs Loyola Chicago betting rundown, featuring our trusted match prediction, most likely correct score outcome and a fully loaded bet builder.

Game Prediction

It’s hard to resist betting Mercyhurst considering they’ve been given +21.5 on the spread. The underdogs are a good shout at -118 to keep things close in this college contest.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key Mercyhurst vs Loyola Chicago stats:

• The +21.5 line has been covered by Mercyhurst in 9 of their last 10 games.
• The +21.5 line has been covered by Mercyhurst in 18 of their last 20 games.
• The -21.5 line hasn’t been covered by Loyola Chicago in 7 consecutive games.
• The -21.5 line hasn’t been covered by Loyola Chicago in 9 of their last 10 games.
• The -21.5 line hasn’t been covered by Loyola Chicago in 18 of their last 20 games.

Mercyhurst +21.5 Probability

The best betting sites suggest there’s a 54.1% chance of our pick delivering a return. After careful examination, our team calculate this probability to be closer to 60%. It is the reason why we are recommending this college basketball wager.

If you’re looking for a good alternative to betting on Mercyhurst on the spread, then consider the Winning Margin. You can choose from a range of fixed intervals and odds.

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Best Bet

Mercyhurst +21.5 @ -118 Bet Now

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Correct Score Prediction

Mercyhurst 62 - 80 Loyola Chicago

There are lots of different ways to back Loyola Chicago on the correct score betting and something like 80-62 in their favor might be along the right lines at massive odds.

Mercyhurst vs Loyola Chicago Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Loyola Chicago Bettors Need to Find Moneyline Alternative

The Spread offers a better alternative to the Moneyline considering Loyola Chicago are huge favorites for this college game. Consider whether to side with them to cover the line or alternatively wager on the underdogs to outperform their odds.

The spread currently stands at 21.5 and the total points line is 145.5. Basketball bettors love the chance to get an alternative angle by going for a Total wager. Those that want to back Under 145.5 can find odds of -110 available.

Consider every angle when placing your college basketball bets. The top betting apps offer a nice selection of team props and game lines and it’s all about finding a wager which matches your prediction of the contest.

Moneyline

Mercyhurst

-

Loyola Chicago

-

Point Spread

Mercyhurst +21.5

-118

Loyola Chicago -21.5

-102

Total Points

Under 145.5

-110

Over 145.5

-110

Player Props & Micro Betting

The gambling sites also allow you to place player prop bets such as Points, Assists, Steals and Rebounds. This means you can focus on an individual player’s performance rather than wager on the actual outcome of the game in question.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Last 5 & H2H

Latest regular season and playoff games stats.

Mercyhurst Stats

Loyola Chicago Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +21.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +21.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -21.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -21.5 Betting Line at Home: Have covered the spread in 1 of the last 10 home games

Total Points

• Game Totals: An average of 142.90 pts in the previous 10 games
• Game Totals on the Road: An average of 135.70 pts in the previous 10 games on the road
• Over 145.5: Covered in 5 of the previous 10 games
• Over 145.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 71.20 pts and allowed 71.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 62.80 pts and allowed 72.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 145.90 pts in the previous 10 games
• Game Totals at Home: An average of 141.10 pts in the previous 10 home games
• Over 145.5: Covered in 5 of the previous 10 games
• Over 145.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 73.60 pts and allowed 72.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 75.30 pts and allowed 65.80 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Dayton	1-0	88	48	40	1-0	0-0	1W
Davidson	1-0	97	63	34	1-0	0-0	1W
Rhode Island	1-0	93	62	31	1-0	0-0	1W
VCU	1-0	103	74	29	1-0	0-0	1W
La Salle	1-0	87	59	28	1-0	0-0	1W
Richmond	1-0	84	56	28	1-0	0-0	1W
Saint Louis	1-0	92	67	25	1-0	0-0	1W
George Mason	1-0	70	46	24	1-0	0-0	1W
Duquesne	1-0	83	63	20	1-0	0-0	1W
George Washington	1-0	67	47	20	1-0	0-0	1W
Saint Joseph's	1-0	85	76	9	1-0	0-0	1W
St. Bonaventure	1-0	69	63	6	1-0	0-0	1W
Loyola Chicago	1-0	91	88	3	1-0	0-0	1W
Fordham	0-1	61	72	-11	0-1	0-0	1L

Northeast	Overall	PF	PA	N. Pts	Home	Away	Strk
Central Conn. St.	1-0	117	55	62	1-0	0-0	1W
Stonehill	1-0	100	48	52	1-0	0-0	1W
Le Moyne	1-0	94	50	44	1-0	0-0	1W
LIU	0-1	67	89	-22	0-0	0-1	1L
Mercyhurst	0-1	47	70	-23	0-0	0-1	1L
New Haven Chargers	0-1	55	79	-24	0-0	0-1	1L
Wagner	0-1	74	103	-29	0-0	0-1	1L
Chicago State	0-1	62	92	-30	0-0	0-1	1L
St. Francis (PA)	0-1	66	102	-36	0-0	0-1	1L
Fairleigh Dickinson	0-1	50	88	-38	0-0	0-1	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak