Mercyhurst vs Loyola Chicago Prediction, Picks & Odds | 06 Nov 2025

College Basketball Betting Preview: Mercyhurst vs Loyola Chicago

The Mercyhurst Lakers battle the Loyola Chicago Ramblers, with tip-off scheduled for 21:00 on Thursday, November 6. Our betting preview features expert NCAAB predictions, betting tips, the latest odds and H2H stats.

There’s a lot to like about Mercyhurst +21.5 when they meet Loyola Chicago. You can get odds of -118 and we need the underdogs to avoid a sizeable defeat.

Mercyhurst Lakers were defeated in their previous game. On the road, they suffered a 70-47 reverse against Northwestern Wildcats.

Loyola Chicago Ramblers were winners last time out. It was a 91-88 home victory against Cleveland State Vikings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Mercyhurst	17-17	2357	2291	66	12-3	5-14	1L
Loyola Chicago	9-24	2204	2500	-296	6-12	3-12	1L

View Full Standings

Mercyhurst vs Loyola Chicago Prediction & Picks

Get ahead of the game with our Mercyhurst vs Loyola Chicago betting rundown, featuring our trusted match prediction, most likely correct score outcome and a fully loaded bet builder.

Game Prediction

It’s hard to resist betting Mercyhurst considering they’ve been given +21.5 on the spread. The underdogs are a good shout at -118 to keep things close in this college contest.

Tracking injury updates is a big part of our college hoops analysis and team news plays a major role in shaping our basketball picks. We combine this with recent form and the most important stats to get a complete picture.

Key Mercyhurst vs Loyola Chicago stats:

• The +21.5 line has been covered by Mercyhurst in 9 of their last 10 games.
• The +21.5 line has been covered by Mercyhurst in 18 of their last 20 games.
• The -21.5 line hasn’t been covered by Loyola Chicago in 7 consecutive games.
• The -21.5 line hasn’t been covered by Loyola Chicago in 9 of their last 10 games.
• The -21.5 line hasn’t been covered by Loyola Chicago in 18 of their last 20 games.

Mercyhurst +21.5 Probability

The best betting sites suggest there’s a 54.1% chance of our pick delivering a return. After careful examination, our team calculate this probability to be closer to 60%. It is the reason why we are recommending this college basketball wager.

If you’re looking for a good alternative to betting on Mercyhurst on the spread, then consider the Winning Margin. You can choose from a range of fixed intervals and odds.

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Our Game Prediction

Mercyhurst +21.5 @ -118 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Nov 6, 05:06). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Mercyhurst 62 - 80 Loyola Chicago

There are lots of different ways to back Loyola Chicago on the correct score betting and something like 80-62 in their favor might be along the right lines at massive odds.

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Mercyhurst vs Loyola Chicago Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The favorites are 99% likely to win according to the sportsbooks’ latest Moneyline odds, with Loyola Chicago priced at -10000 to triumph in this college game. Mercyhurst are trading at bigger odds than their opponents and they can be backed at +1800.

The spread currently stands at 21.5 and the total points line is 144.5. Basketball bettors love the chance to get an alternative angle by going for a Total wager. Those that want to back Under 144.5 can find odds of -110 available.

Consider every angle when placing your college basketball bets. The top betting apps offer a nice selection of team props and game lines and it’s all about finding a wager which matches your prediction of the contest.

Moneyline

Mercyhurst

+1800

Loyola Chicago

-10000

Point Spread

Mercyhurst +21.5

-106

Loyola Chicago -21.5

-114

Total Points

Under 144.5

-110

Over 144.5

-110

The gambling sites also allow you to place player prop bets such as Points, Assists, Steals and Rebounds. This means you can focus on an individual player’s performance rather than wager on the actual outcome of the game in question.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Latest regular season and playoff games stats.

Mercyhurst Stats

Loyola Chicago Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +21.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +21.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -21.5 Betting Line: Have covered the spread in 1 of the last 10 games
• -21.5 Betting Line at Home: Have covered the spread in 1 of the last 10 home games

Total Points

• Game Totals: An average of 142.90 pts in the previous 10 games
• Game Totals on the Road: An average of 135.70 pts in the previous 10 games on the road
• Over 145.5: Covered in 5 of the previous 10 games
• Over 145.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 71.20 pts and allowed 71.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 62.80 pts and allowed 72.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 145.90 pts in the previous 10 games
• Game Totals at Home: An average of 141.10 pts in the previous 10 home games
• Over 145.5: Covered in 5 of the previous 10 games
• Over 145.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 73.60 pts and allowed 72.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 75.30 pts and allowed 65.80 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	28-5	2879	2294	585	21-2	7-3	1L
VCU	27-7	2773	2430	343	19-3	8-4	6W
George Mason	23-9	2347	2160	187	17-3	6-6	1L
Dayton	23-11	2528	2376	152	16-4	7-7	1L
Saint Joseph's	22-11	2419	2306	113	16-3	6-8	1L
Davidson	20-13	2367	2225	142	12-8	8-5	1L
Duquesne	18-15	2584	2481	103	13-7	5-8	1L
George Washington	18-15	2708	2433	275	13-5	5-10	1L
Fordham	17-15	2235	2095	140	12-8	5-7	1L
Rhode Island	16-16	2236	2182	54	10-7	6-9	2L
St. Bonaventure	17-17	2596	2532	64	10-7	7-10	1L
Richmond	15-17	2455	2366	89	11-8	4-9	4L
La Salle	9-23	2148	2370	-222	7-9	2-14	2L
Loyola Chicago	9-24	2204	2500	-296	6-12	3-12	1L

Northeast	Overall	PF	PA	N. Pts	Home	Away	Strk
LIU	24-10	2519	2418	101	14-1	10-9	5W
Central Conn. St.	18-12	2215	2127	88	10-4	8-8	1L
Mercyhurst	17-17	2357	2291	66	12-3	5-14	1L
Le Moyne	15-17	2336	2341	-5	10-4	5-13	2L
New Haven	14-17	2013	2055	-42	9-6	5-11	1W
Wagner	13-17	2118	2186	-68	7-5	6-12	1L
Stonehill	12-21	2191	2263	-72	8-6	4-15	1L
Fairleigh Dickinson	11-21	2150	2245	-95	8-6	3-15	4L
St. Francis (PA)	7-24	2216	2510	-294	5-9	2-15	2L
Chicago State	7-25	2105	2434	-329	5-6	2-19	3L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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