Notre Dame vs Houston Prediction, Picks & Odds | 26 Nov 2025

College Basketball Betting Preview: Notre Dame vs Houston

The Notre Dame Fighting Irish square off against the Houston Cougars, with tip-off scheduled for 15:30 on Wednesday, November 26.

Houston can enjoy a huge victory and a wager on the spread could be the best way forward. Back the big favorites off -10.5 to cover the line against Notre Dame at -110.

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Notre Dame Fighting Irish previous game saw them claim a 68-63 home win over Rutgers Scarlet Knights.

Houston Cougars were defeated last time out. They were beaten at home to Tennessee Volunteers by a 76-73 scoreline.

Head-to-Head Statistics

The last matchup between Houston and Notre Dame saw the former win. It was a 65-54 scoreline.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Houston	6-1	533	417	116	5-1	1-0	1L
Notre Dame	5-2	547	472	75	5-0	0-2	1W

View Full Standings

Notre Dame vs Houston Prediction & Picks

Explore our best Notre Dame vs Houston picks, including a main match prediction, correct score forecast and a bet builder ready to use. Scroll down for full analysis.

Game Prediction

We’re predicting that this could be a one-sided college affair. Our pick is to therefore take Houston at -110 to cover the -10.5 line on the spread.

It’s important to know which players are unavailable for the upcoming college hoops action along with the current form of each team. If you're after stats, you're in the right place because they form the foundation of our basketball predictions.

Key Notre Dame vs Houston stats:

• The -10.5 line has been covered by Houston in 3 of their last 5 games at home.

Houston -10.5 Probability

The latest odds at the best betting apps suggest our pick carries a 52.4% chance of winning. After careful examination, our analysts calculate this probability to be closer to 60%. It is therefore regarded as a value bet.

If you want to pimp the odds about Houston covering the line, you might consider going down the Bet Builder route and combine this prediction with other selections.

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Our Game Prediction

Houston -10.5 @ -110 Bet Now

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Correct Score Prediction

Notre Dame 64 - 77 Houston

There are a range of correct score lines to choose from and we’re taking a chance on the Coogs to record a 77-64 victory. There’s a huge return if we get this right.

Notre Dame vs Houston Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The sportsbooks make this game uncompetitive, with Houston expected to comfortably win. Therefore, the Moneyline might not be available and it’s better to instead play the spread to assess the various options.

The spread currently stands at 10.5 and the total points line is 134.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. If you're keen on Over 134.5, this selection is available at -110.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Notre Dame

-

Houston

-

Point Spread

Notre Dame +10.5

-110

Houston -10.5

-110

Total Points

Under 134.5

-110

Over 134.5

-110

The best gambling sites offer player prop betting to their customers. These can be a great alternative if you want to focus on an individual’s performance within a game and it often involves wagering over or under a line.

It’s possible to use stats to your advantage when it comes to college basketball micro betting, especially if you’re predicting outcomes such as the Next Field Goal. Check out the live player, score and team props to see if you can find an angle.

Latest regular season and playoff games stats.

Notre Dame Stats

Houston Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +10.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +10.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -10.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -10.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 148.20 pts in the previous 10 games
• Game Totals on the Road: An average of 140.40 pts in the previous 10 games on the road
• Over 134.5: Covered in 5 of the previous 10 games
• Over 134.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 77.00 pts and allowed 71.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 67.60 pts and allowed 72.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 133.40 pts in the previous 10 games
• Game Totals at Home: An average of 133.10 pts in the previous 10 home games
• Over 134.5: Covered in 5 of the previous 10 games
• Over 134.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 73.50 pts and allowed 59.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 73.50 pts and allowed 59.60 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big 12	Overall	PF	PA	N. Pts	Home	Away	Strk
Iowa State	6-0	543	391	152	4-0	2-0	6W
Oklahoma State	6-0	559	446	113	6-0	0-0	6W
Arizona	6-0	513	408	105	4-0	2-0	6W
Colorado	5-0	472	408	64	5-0	0-0	5W
Houston	6-1	533	417	116	5-1	1-0	1L
UCF	6-1	624	558	66	5-1	1-0	5W
Arizona State	6-1	572	525	47	4-1	2-0	4W
Cincinnati	5-1	472	385	87	5-1	0-0	1W
BYU	4-1	436	343	93	4-1	0-0	1W
Baylor	4-1	430	401	29	4-1	0-0	1L
Kansas	5-2	529	440	89	5-0	0-2	2W
West Virginia	5-2	499	422	77	5-0	0-2	2L
Kansas State	5-2	626	563	63	5-0	0-2	2L
Utah	5-2	576	549	27	5-1	0-1	2L
Texas Tech	4-2	493	450	43	4-0	0-2	1L
TCU	3-2	400	318	82	3-2	0-0	1W

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	7-0	655	399	256	6-0	1-0	7W
Louisville	6-0	573	394	179	5-0	1-0	6W
North Carolina	6-0	525	386	139	6-0	0-0	6W
SMU	7-0	649	511	138	7-0	0-0	7W
Virginia Tech	5-0	461	364	97	5-0	0-0	5W
Clemson	6-1	590	454	136	5-0	1-1	3W
California	6-1	591	487	104	6-0	0-1	3W
Georgia Tech	5-1	437	381	56	5-0	0-1	2W
Virginia	5-1	519	404	115	4-0	1-1	1L
NC State	5-1	558	434	124	4-1	1-0	1W
Florida State	5-1	559	422	137	5-0	0-1	3W
Miami	5-1	553	386	167	5-0	0-1	2W
Stanford	4-1	419	358	61	4-1	0-0	1L
Wake Forest	5-2	613	502	111	4-0	1-2	2W
Notre Dame	5-2	547	472	75	5-0	0-2	1W
Syracuse	4-2	460	362	98	3-0	1-2	2L
Pittsburgh	4-3	505	466	39	4-1	0-2	2L
Boston College	3-4	491	465	26	2-3	1-1	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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