Penn vs Drexel Prediction, Picks & Odds | 21 Nov 2025

College Basketball Betting Preview: Penn vs Drexel

The Penn Quakers square off against the Drexel Dragons, with tip-off scheduled for 19:00 on Friday, November 21.

There’s a great opportunity to cover the spread by backing Drexel at -5.5. We can get odds of -110 and our prediction is that they’ll overcome Penn.

Like our read on the spread? Grab the latest BetMGM promo code and read our honest review of the site before you decide where to put your money.

Penn Quakers claimed a victory in their previous game. A 83-74 home win occurred against Saint Joseph's Hawks.

Drexel Dragons won their last game which was at home. It was a 75-43 triumph against NJIT Highlanders.

Head-to-Head Statistics

The scoreline was 60-47 in favor of Drexel when they last played Penn.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Penn	2-2	361	336	25	2-0	0-2	1W
Drexel	2-3	366	348	18	2-1	0-2	1W

View Full Standings

Penn vs Drexel Prediction & Picks

Our Penn vs Drexel betting guide delivers expert insight, including a main match pick, our correct score angle and bet builder recommendations. Dive into each section below for more.

Game Prediction

Drexel should secure a comfortable win and a bet on the spread could be the best way forward in this college matchup. Back this selection off -5.5 to cover the line at odds of -110.

We only make our basketball picks after confirming the latest college hoops team news. Studying recent form and digging into the most relevant stats also helps us build a complete picture.

Key Penn vs Drexel stats:

• The -5.5 line has been covered by Drexel in 4 of their last 5 games at home.
• The -5.5 line has been covered by Drexel in 7 of their last 10 games at home.
• The +5.5 line hasn’t been covered by Penn in 4 of their last 5 games on the road.
• The +5.5 line hasn’t been covered by Penn in 6 of their last 10 games on the road.
• The +5.5 line hasn’t been covered by Penn in 3 consecutive games on the road.

Drexel -5.5 Probability

According to the top betting apps, there’s a 52.4% likelihood of our pick delivering a return. However, we think that the probability sits between 55-60% taking all factors into consideration. This is why we regard this as a value bet.

A Bet Builder provides you with the chance to combine Drexel against the spread with other picks. For every additional selection, the odds are boosted.

Before you dive in, check our guide for the newest betting promotions and generous sign-up bonuses.

Our Game Prediction

Drexel -5.5 @ -110 Bet Now

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Correct Score Prediction

Penn 75 - 85 Drexel

Rather than betting on Drexel to win, there’s the option to try your luck when it comes to the correct score lines. Take a chance on a 85-75 triumph in their favor.

Penn vs Drexel Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The sportsbooks’ betting odds have Drexel as -263 favorites for this college game, implying that they are 72% likely to win. The market suggests that Penn are least likely to win at +215.

The current spread is 5.5 and total points is 152.5. There is no denying the popularity of betting on the Totals. If you want to back Over 152.5, it’s -110.

The best betting sites offer stacks of team props and game lines when it comes to most college basketball contests. Make sure you look through all the available options before deciding which bet to place.

Moneyline

Penn

+215

Drexel

-263

Point Spread

Penn +5.5

-110

Drexel -5.5

-110

Total Points

Under 152.5

-110

Over 152.5

-110

The gambling sites will have player props available for each game. Check out the various betting odds and take a view on whether a player’s Total Points, Three-Pointers, Blocks or Steals will hit over or under a certain line.

Instead of focusing on the overall outcome, some bettors prefer to look at the college basketball micro betting lines. As the name suggests, it means placing short-term in-game wagers and this might include Next Field Goal, with the options being for a two-pointer or a three-pointer.

Latest regular season and playoff games stats.

Penn Stats

Drexel Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +5.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +5.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -5.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -5.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 166.80 pts in the previous 10 games
• Game Totals on the Road: An average of 158.70 pts in the previous 10 games on the road
• Over 152.5: Covered in 9 of the previous 10 games
• Over 152.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 82.40 pts and allowed 84.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 74.50 pts and allowed 84.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 139.30 pts in the previous 10 games
• Game Totals at Home: An average of 135.40 pts in the previous 10 home games
• Over 152.5: Covered in 3 of the previous 10 games
• Over 152.5 at Home: Covered in 2 of the previous 10 home games
• Team Totals: Have scored an average of 72.10 pts and allowed 67.20 pts in the last 10 games
• Team Totals at Home: Have scored an average of 72.90 pts and allowed 62.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Coastal Athletic Association	Overall	PF	PA	N. Pts	Home	Away	Strk
Stony Brook	4-1	403	318	85	4-0	0-1	1W
UNC Wilmington	3-1	341	283	58	3-0	0-1	2W
NC A&T	3-1	325	309	16	2-0	1-1	3W
Towson	3-2	342	305	37	2-0	1-2	1L
Elon	3-2	447	420	27	2-0	1-2	1L
William & Mary	3-2	419	398	21	1-0	2-2	1W
Hofstra	2-3	405	382	23	1-0	1-3	1L
Drexel	2-3	366	348	18	2-1	0-2	1W
Campbell	2-3	413	397	16	2-0	0-3	1L
Charleston	2-3	381	374	7	2-2	0-1	1L
Northeastern	2-3	351	356	-5	0-2	2-1	2L
Hampton	2-4	427	417	10	1-1	1-3	2L
Monmouth	1-3	287	289	-2	1-0	0-3	3L

Ivy League	Overall	PF	PA	N. Pts	Home	Away	Strk
Yale	3-1	357	293	64	1-1	2-0	1L
Columbia	3-1	273	263	10	2-0	1-1	2W
Harvard	4-2	436	392	44	2-1	2-1	1L
Cornell	3-2	445	431	14	2-0	1-2	3W
Penn	2-2	361	336	25	2-0	0-2	1W
Princeton	3-3	438	448	-10	3-0	0-3	1W
Dartmouth	1-3	321	310	11	1-2	0-1	1W
Brown	1-5	408	442	-34	1-3	0-2	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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