Philadelphia 76ers vs Boston Celtics Prediction, Picks & Odds | 22 Oct 2025

NBA Betting Preview: Sixers vs Celtics

The Philadelphia 76ers go up against the Boston Celtics in this NBA matchup at TD Garden, with tip-off scheduled for 19:30 on Wednesday, October 22. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, player stats, team news and the official starting lineups.

Under 227.5 Looks Value

Go for Under at -106. It might be defenses on top when the Sixers clash with the Celtics, with the 227.5 line looking on the high side when it comes to the totals.

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8 Wins in Previous 10 H2H Games for Celtics

The Philadelphia 76ers closed out their 2024–25 campaign with a 122–102 home loss to the Chicago Bulls at Xfinity Mobile Arena. Lonnie Walker scored 31 points, with Jared Butler getting 19 and Adem Bona 16.

The Boston Celtics ended last season with a 4–2 series loss to the New York Knicks in the Eastern Conference Semifinals. In Game 6, they fell 119–81 on the road at Madison Square Garden. Jaylen Brown was able to score 20 points, with Payton Pritchard getting 11 and Al Horford 10.

Head-to-Head Statistics

The Celtics triumphed 123-105 when they last played the Sixers. This head-to-head was played at TD Garden. It’s been three victories on the bounce for the Celtics when playing the Sixers. On the head-to-head front, they have won 8 of the past 10.

NBA	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Celtics	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
76ers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

View Full Standings

The Sixers have 1 win and 9 losses in the past 10 games. They are averaging 107.0 points, 43.9 rebounds, 24.3 assists, 7.8 steals and 5.9 blocks while shooting 44.6% from the field and 74.5% from the free-throw line. The opposition average 117.5 points and 47.9 rebounds per matchup.

Quentin Grimes is averaging 16.9 points, Adem Bona 8.3 rebounds and Jared Butler 5.9 assists, while Lonnie Walker averages 2.8 (36.8%) 3-pointers made.

The Celtics have won 5 and lost 5 of their last 10 contests. Averaging 106.0 points, 43.2 rebounds, 19.8 assists, 6.1 steals and 5.4 blocks per game while shooting 44.2% from the field and 80.5% from the free-throw line. Their opponents have an average of 101.6 points and 43.4 rebounds.

Jaylen Brown is averaging 22.7 points and 4.1 assists, while Jayson Tatum has an average of 7.8 rebounds and Derrick White 3.3 (35.9%) 3-pointers made.

Philadelphia 76ers vs Boston Celtics Prediction & Picks

Discover our expert Philadelphia 76ers vs Boston Celtics betting tips, featuring a key match prediction, correct score suggestion, top player prop picks and bet builder advice. Scroll down for full analysis.

Game Prediction

When the teams line up in this NBA contest, we’re not sure that the total points will go over the line. Based on this pick, you can land odds of -106 for Under 227.5 and this looks worth taking.

Our team of expert NBA handicappers track current injuries closely. Combined with recent form, this helps us identify the best value odds. A data-led approach backed by key stats and the latest team news keeps our analysis sharp.

Key 76ers vs Celtics stats:

• The 227.5 line hasn’t been covered in the last 4 Sixers games on the road.
• The 227.5 line hasn’t been covered in 6 of the last 10 Sixers games.
• The 227.5 line hasn’t been covered in 9 of the last 10 Celtics games at home.
• The 227.5 line hasn’t been covered in 16 of the last 20 Celtics games.

Under 227.5 Probability

Looking at the latest odds, our pick has a 51.5% chance of delivering a return. However, our research has found that the actual probability is closer to 60%. It’s the reason why we are recommending this bet.

It’s all about getting the best odds and one way of maximising your Unders wager is by combining it with the winner on the Match Result & Total lines.

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Best Bet

Under 227.5 Points @ -106 Watch Live Bet Now

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Player Prop Picks

Top Pick: Payton Pritchard Under 4.5 Assists +118

Payton Pritchard (Celtics) has finished with Under 4.5 assists in 8 of the past 10 games. Based on this stat, it could be that he doesn’t cover the line and this Player Assists wager is available at +118.

Latest Payton Pritchard Player Prop Odds

Points

Over 16.5

-112

Under 16.5

-120

Assists

Over 4.5

-154

Under 4.5

+116

Rebounds

Over 4.5

+110

Under 4.5

-147

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Quentin Grimes Over 3.5 Assists -106

Quentin Grimes (76ers) has recorded Over 3.5 assists in 4 straight road games. We’re sweet on him covering the Player Assists line once again, with odds of -106 on offer that this happens.

Latest Quentin Grimes Player Prop Odds

Points

Over 13.5

-123

Under 13.5

-108

Assists

Over 3.5

-106

Under 3.5

-122

Rebounds

Over 3.5

-156

Under 3.5

+117

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Correct Score Prediction

76ers 109 - 115 Celtics

Let’s roll the dice and try the Celtics to enjoy a 115-109 winning scoreline here. There are massive odds for this potential outcome and it’s a fun type of wager to enjoy.

Philadelphia 76ers vs Boston Celtics Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Close Encounter in the Eyes of the Books

Boston Celtics are -132 to win against Philadelphia 76ers who are priced at betting odds of +112. In the eyes of the leading NBA sportsbooks, the home team are regarded as 57% likely to claim a victory.

The spread is calculated to be 2, while total points comes in at 228. There is no denying the popularity of wagering on the Totals. If you’re going for Under 228, this outcome can be backed at -110.

There are hundreds of game lines and team props when it comes to wagering on this popular basketball league and we recommend visiting the top betting sites to find the wager that matches your view on the contest.

Moneyline

76ers

+112

Celtics

-132

Point Spread

76ers +2

-108

Celtics -2

-112

Total Points

Under 228

-110

Over 228

-110

Joel Embiid Favorite to Get Most Points

Joel Embiid is favorite when it comes to getting the most points. You can get -114 that he goes Over 25.5 points and -118 when it comes to Under.

Joel Embiid (76ers)

Over 25.5

-114

Under 25.5

-118

Tyrese Maxey (76ers)

Over 25.5

-110

Under 25.5

-120

Jaylen Brown (Celtics)

Over 24.5

-109

Under 24.5

-122

Derrick White (Celtics)

Over 19.5

-122

Under 19.5

-109

Anfernee Simons (Celtics)

Over 16.5

-122

Under 16.5

-108

Payton Pritchard (Celtics)

Over 16.5

-112

Under 16.5

-120

Quentin Grimes (76ers)

Over 13.5

-123

Under 13.5

-108

Kelly Oubre Jr (76ers)

Over 11.5

-120

Under 11.5

-112

VJ Edgecombe (76ers)

Over 11.5

-110

Under 11.5

-120

Sam Hauser (Celtics)

Over 9.5

-108

Under 9.5

-123

Chris Boucher (Celtics)

Over 8.5

-114

Under 8.5

-114

Neemias Queta (Celtics)

Over 7.5

-120

Under 7.5

-110

Adem Bona (76ers)

Over 6.5

-112

Under 6.5

-115

Derrick White (Celtics)

Over 6.5

-114

Under 6.5

-118

Tyrese Maxey (76ers)

Over 5.5

-127

Under 5.5

-105

Joel Embiid (76ers)

Over 4.5

-127

Under 4.5

-105

Jaylen Brown (Celtics)

Over 4.5

-154

Under 4.5

+117

Payton Pritchard (Celtics)

Over 4.5

-154

Under 4.5

+116

Anfernee Simons (Celtics)

Over 3.5

-152

Under 3.5

+114

Quentin Grimes (76ers)

Over 3.5

-106

Under 3.5

-122

VJ Edgecombe (76ers)

Over 2.5

-114

Under 2.5

-118

Joel Embiid (76ers)

Over 8.5

-137

Under 8.5

+104

Neemias Queta (Celtics)

Over 7.5

+106

Under 7.5

-139

Jaylen Brown (Celtics)

Over 6.5

+105

Under 6.5

-139

Kelly Oubre Jr (76ers)

Over 5.5

+112

Under 5.5

-149

Chris Boucher (Celtics)

Over 5.5

-141

Under 5.5

+108

Adem Bona (76ers)

Over 5.5

-123

Under 5.5

-105

Derrick White (Celtics)

Over 4.5

-152

Under 4.5

+114

Payton Pritchard (Celtics)

Over 4.5

+110

Under 4.5

-147

VJ Edgecombe (76ers)

Over 4.5

-114

Under 4.5

-118

Tyrese Maxey (76ers)

Over 3.5

+132

Under 3.5

-179

Quentin Grimes (76ers)

Over 3.5

-156

Under 3.5

+117

Anfernee Simons (Celtics)

Over 2.5

-133

Under 2.5

+103

Micro Betting

Micro betting is something that’s really popular with bettors, with basketball fans essentially being able to wager in-game when it comes to score, team and player props. Check out the two-way lines where you can bet whether the next shot will be a Two-pointer or a Three-pointer.

Last 5 & H2H

Latest regular season and playoff games stats.

Philadelphia 76ers Stats

Boston Celtics Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +2 Betting Line: Have covered the spread in 1 of the last 10 games
• +2 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road

Point Spread

• -2 Betting Line: Have covered the spread in 5 of the last 10 games
• -2 Betting Line at Home: Have covered the spread in 8 of the last 10 home games

Total Points

• Game Totals: An average of 224.50 pts in the previous 10 games
• Game Totals on the Road: An average of 234.50 pts in the previous 10 games on the road
• Over 227.5: Covered in 4 of the previous 10 games
• Over 227.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 107.00 pts and allowed 117.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 112.80 pts and allowed 121.70 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 207.60 pts in the previous 10 games
• Game Totals at Home: An average of 207.30 pts in the previous 10 home games
• Over 227.5: Covered in 2 of the previous 10 games
• Over 227.5 at Home: Covered in 1 of the previous 10 home games
• Team Totals: Have scored an average of 106.00 pts and allowed 101.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 112.40 pts and allowed 94.90 pts in the last 10 home games

Team Stats - Avg/Game

Last 10 Games

• 2-Pointers Made: 28.20 (55%)
• 3-Pointers Made: 11.70 (31%)
• Free Throws Made: 15.50 (74.52%)
• Rebounds: Total 43.9, Offensive 11.80, Defensive 32.10
• Assists: 24.30
• Blocks: 5.90
• Steals: 7.80
• Turnovers : 13.50
• Personal Fouls: 17.00

Last 10 Games on the Road

• 2-Pointers Made: 26.70 (55%)
• 3-Pointers Made: 13.60 (33%)
• Free Throws Made: 18.60 (75%)
• Rebounds: Total 40.3, Offensive 11.40, Defensive 28.90
• Assists: 22.10
• Blocks: 5.20
• Steals: 9.90
• Turnovers : 13.60
• Personal Fouls: 18.00

Team Stats - Avg/Game

Last 10 Games

• 2-Pointers Made: 22.70 (52%)
• 3-Pointers Made: 14.00 (35%)
• Free Throws Made: 18.60 (80.52%)
• Rebounds: Total 43.2, Offensive 11.00, Defensive 32.20
• Assists: 19.80
• Blocks: 5.40
• Steals: 6.10
• Turnovers : 12.20
• Personal Fouls: 20.20

Last 10 Home Games

• 2-Pointers Made: 24.20 (54%)
• 3-Pointers Made: 16.30 (38%)
• Free Throws Made: 15.10 (77.44%)
• Rebounds: Total 49.2, Offensive 13.20, Defensive 36.00
• Assists: 24.90
• Blocks: 5.70
• Steals: 6.80
• Turnovers : 11.00
• Personal Fouls: 16.10

Live Streaming

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Team News

Injuries & Suspensions

Starting Lineups

Both teams’ confirmed lineups will be published ahead of tip-off. There is also the chance to look at the lineups from the previous 10 games.

NBA Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Division Conference League

East Atlantic	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Celtics	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Nets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Knicks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
76ers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Raptors	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

East Central	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Bulls	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Cavaliers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pistons	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pacers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Bucks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

East Southeast	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Hawks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Hornets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Heat	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Magic	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Wizards	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

West Northwest	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Thunder	1	0	1	125	124	1	1-0	0-0	0-0	1-0	1-0	1W
Nuggets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Timberwolves	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Trail Blazers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Jazz	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

West Pacific	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Warriors	1	0	1	119	109	10	0-0	1-0	1-0	1-0	1-0	1W
Lakers	0	1	0	109	119	-10	0-1	0-0	0-1	0-1	0-1	1L
Clippers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Suns	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Kings	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

West Southwest	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Rockets	0	1	0	124	125	-1	0-0	0-1	0-0	0-1	0-1	1L
Mavericks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Grizzlies	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pelicans	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Spurs	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

Eastern Conference	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Celtics	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Nets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Knicks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
76ers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Raptors	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Bulls	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Cavaliers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pistons	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pacers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Bucks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Hawks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Hornets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Heat	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Magic	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Wizards	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

Western Conference	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Warriors	1	0	1	119	109	10	0-0	1-0	1-0	1-0	1-0	1W
Thunder	1	0	1	125	124	1	1-0	0-0	0-0	1-0	1-0	1W
Rockets	0	1	0	124	125	-1	0-0	0-1	0-0	0-1	0-1	1L
Lakers	0	1	0	109	119	-10	0-1	0-0	0-1	0-1	0-1	1L
Nuggets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Timberwolves	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Trail Blazers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Jazz	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Clippers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Suns	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Kings	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Mavericks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Grizzlies	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pelicans	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Spurs	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

NBA	W	L	PCT	PPG	OPP PPG	DIFF	Home	Road	Div	Conf	Last 10	Strk
Warriors	1	0	1	119	109	10	0-0	1-0	1-0	1-0	1-0	1W
Thunder	1	0	1	125	124	1	1-0	0-0	0-0	1-0	1-0	1W
Hawks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Celtics	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Nets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Hornets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Bulls	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Cavaliers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Mavericks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Nuggets	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pistons	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Rockets	0	1	0	124	125	-1	0-0	0-1	0-0	0-1	0-1	1L
Pacers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Clippers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Lakers	0	1	0	109	119	-10	0-1	0-0	0-1	0-1	0-1	1L
Grizzlies	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Heat	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Bucks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Timberwolves	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Pelicans	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Knicks	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Magic	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
76ers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Suns	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Trail Blazers	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Kings	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Spurs	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Raptors	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Jazz	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-
Wizards	0	0	0	0	0	0	0-0	0-0	0-0	0-0	-	-

• W = Wins
• L = Losses
• PCT = Winning Percentage
• PPG = Points Per Game
• OPP PPG = Opponent Points Per Game
• DIFF = Average Point Differential
• Home = Home Record
• Road = Away Record
• Div = Division Record
• Conf = Conference Record
• Last 10 = Record last 10 games
• Strk = Current Streak