Purdue Fort Wayne vs Saint Louis Prediction, Picks & Odds | 21 Nov 2025

College Basketball Betting Preview: Purdue Fort Wayne vs Saint Louis

The Purdue Fort Wayne Mastodons go up against the Saint Louis Billikens, with tip-off scheduled for 20:00 on Friday, November 21.

There’s every chance that the total won’t be as high as 166.5, so we’re prepared to take the -115 that Purdue Fort Wayne and Saint Louis go under the line.

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Purdue Fort Wayne Mastodons lost on the road in their previous game. Utah Utes won 85-77.

Saint Louis Billikens won their last game which was at home. It was a 78-64 triumph against Grand Canyon Antelopes.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	4-0	387	283	104	4-0	0-0	4W
Fort Wayne	2-4	542	476	66	2-0	0-4	1L

View Full Standings

Purdue Fort Wayne vs Saint Louis Prediction & Picks

Gear up for Purdue Fort Wayne vs Saint Louis with our betting guide, featuring an expert match prediction, scoreline advice and a hand-picked bet builder. Explore each section below for detailed insights.

Game Prediction

There are good reasons for anticipating that the points tally will be lower than the line in this college showdown. If you agree with our pick of Under 166.5, you will find -115 available.

The college hoops handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our basketball picks.

Key Purdue Fort Wayne vs Saint Louis stats:

• The 166.5 line hasn’t been covered in the last 9 Fort Wayne games on the road.
• The 166.5 line hasn’t been covered in 16 of the last 20 Fort Wayne games.
• The 166.5 line hasn’t been covered in 16 of the last 20 Saint Louis games.
• The 166.5 line hasn’t been covered in 7 of the last 10 Saint Louis games at home.

Under 166.5 Probability

Based on the odds from the top betting sites, there’s a 53.5% likelihood of our pick delivering a return. However, our cappers in-depth research has found that the actual probability is closer to 60%. That means we’re regarding it as a value bet.

For a bigger payout, many bettors will include their Under pick on the Totals with other selections. A Bet Builder is perfect for combining all your predictions.

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Our Game Prediction

Under 166.5 Points @ -115 Bet Now

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Correct Score Prediction

Fort Wayne 68 - 91 Saint Louis

If you want to achieve a big return from your stake, then it’s worth checking out the correct score lines. Saint Louis to claim a 91-68 victory is on offer at huge betting odds.

Purdue Fort Wayne vs Saint Louis Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The latest Moneyline betting odds give Saint Louis a 97% chance of winning this college game which means they’re overwhelming -3333 favorites with the sportsbooks. For those wanting to back Purdue Fort Wayne, you will find +1400 about the underdogs.

The spread is currently 20.5, with the total points line at 166.5. There are many ways to bet on basketball including the Totals. If you want to bet Under 166.5, there are odds of -115.

There are stacks of game lines and team props s when it comes to wagering on college basketball and we recommend visiting the top betting apps to find the bet that matches your view on the contest.

Moneyline

IPFW

+1400

Saint Louis

-3333

Point Spread

IPFW +20.5

-115

Saint Louis -20.5

-105

Total Points

Under 166.5

-115

Over 166.5

-105

If you have a view on Total Points, Three-Pointers, Assists, Double-Doubles or Triple-Doubles, then the player prop betting could be up your street. It’s a great way of wagering on individual performance.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Latest regular season and playoff games stats.

Purdue Fort Wayne Stats

Saint Louis Stats

Moneyline

• 3 wins and 7 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +20.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +20.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -20.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -20.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 158.10 pts in the previous 10 games
• Game Totals on the Road: An average of 154.30 pts in the previous 10 games on the road
• Over 166.5: Covered in 2 of the previous 10 games
• Over 166.5 on the Road: Covered in 1 of the previous 10 games on the road
• Team Totals: Have scored an average of 82.00 pts and allowed 76.10 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 72.30 pts and allowed 82.00 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 163.00 pts in the previous 10 games
• Game Totals at Home: An average of 160.20 pts in the previous 10 home games
• Over 166.5: Covered in 4 of the previous 10 games
• Over 166.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 86.70 pts and allowed 76.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 87.60 pts and allowed 72.60 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
George Washington	5-0	458	334	124	5-0	0-0	5W
Saint Louis	4-0	387	283	104	4-0	0-0	4W
George Mason	5-0	392	299	93	5-0	0-0	5W
Richmond	4-0	348	268	80	4-0	0-0	4W
Davidson	4-0	335	274	61	3-0	1-0	4W
St. Bonaventure	5-0	392	340	52	5-0	0-0	5W
Rhode Island	4-1	404	339	65	3-1	1-0	3W
Dayton	4-1	395	346	49	3-0	1-1	2W
Duquesne	4-1	431	389	42	4-0	0-1	1W
Fordham	4-2	466	361	105	4-1	0-1	2W
VCU	2-2	337	300	37	2-0	0-2	1L
La Salle	2-3	347	362	-15	2-1	0-2	3L
Saint Joseph's	2-3	379	417	-38	2-0	0-3	3L
Loyola Chicago	1-4	359	400	-41	1-3	0-1	4L

Horizon League	Overall	PF	PA	N. Pts	Home	Away	Strk
Northern Kentucky	3-2	436	378	58	2-0	1-2	2W
Robert Morris	3-2	385	359	26	2-0	1-2	1L
Wright State	3-3	488	377	111	3-2	0-1	1W
Youngstown State	2-3	419	384	35	1-0	1-3	2L
Milwaukee	2-3	391	425	-34	2-0	0-3	2L
Fort Wayne	2-4	542	476	66	2-0	0-4	1L
IU Indy	2-4	574	587	-13	1-1	1-3	1L
Cleveland State	2-4	479	545	-66	2-1	0-3	1L
Oakland	1-4	396	420	-24	1-0	0-4	1L
Detroit	1-4	378	409	-31	1-1	0-3	2L
Green Bay	1-4	336	392	-56	1-0	0-4	2L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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