San Francisco vs Saint Louis Prediction, Picks & Odds | 13 Dec 2025

College Basketball Betting Preview: San Francisco vs Saint Louis

The San Francisco Dons face the Saint Louis Billikens, with tip-off scheduled for 20:00 on Saturday, December 13.

We’re really sweet on the big favorites who are -10.5 on the spread. Saint Louis should enjoy a huge victory against San Francisco and cover the line at -120.

San Francisco Dons got the win in their previous game. A 65-62 triumph occurred on the road when playing Mississippi State Bulldogs.

Saint Louis Billikens won their last game which was at home. It was a 107-65 triumph against Central Michigan Chippewas.

Head-to-Head Statistics

San Francisco beat Saint Louis when the teams last met. It was a 78-61 scoreline.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	26-3	2586	1992	594	19-1	7-2	1W
San Francisco	16-15	2305	2271	34	10-6	6-9	1W

View Full Standings

San Francisco vs Saint Louis Prediction & Picks

Get the edge with our San Francisco vs Saint Louis betting tips: our expert match prediction, most likely correct score outcome and a bet builder tailored for value.

Game Prediction

Saint Louis can enjoy a huge victory in this college matchup and a wager on the spread could be the best way forward. Back the big favorites off -10.5 to cover the line at -120.

We keep a close eye on team news and our college basketball handicappers stay sharp by tracking the latest form and lineups. You’ll also find a full set of stats that offer valuable insight and help shape smarter predictions ahead of the action.

Key San Francisco vs Saint Louis stats:

• The -10.5 line has been covered by Saint Louis in 7 of their last 10 games.
• The -10.5 line has been covered by Saint Louis in 3 of their last 5 games.
• The -10.5 line has been covered by Saint Louis in 2 consecutive games.

Saint Louis -10.5 Probability

Looking at the latest betting odds, our pick has a 54.6% chance of winning. However, our analysts research has found that the actual probability is closer to 60%. This college basketball wager can therefore be backed with confidence.

If you want bigger odds, then you can move the line by selling points. Choose how many to sell until you are happy with the juice available.

Maximize your betting potential with the latest free bets, sign-up and welcome offers — all listed in our expert bonus guide.

Our Game Prediction

Saint Louis -10.5 @ -120 Bet Now

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Correct Score Prediction

San Francisco 67 - 80 Saint Louis

Should you wish to go for a speculative bet, try Saint Louis to win 80-67 on the correct score lines. This should be a fun wager which could potentially yield a huge return.

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San Francisco vs Saint Louis Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Saint Louis are massive -833 favorites. They are regarded as 89% likely to win this college game judging by the sportsbooks’ latest Moneyline odds. If you’re looking for an alternative angle, San Francisco are trading at +570.

11.5 is the spread and 153.5 is the total points line. The Totals offers basketball fans an alternative way of getting involved. There’s the chance to back Under 153.5 at -110.

Whether you’re betting in-game or pre-game, the best betting apps serve up a wide range of game lines and team props to choose from. The options are nearly endless, and it’s awesome to have so much variety.

Moneyline

San Francisco

+570

Saint Louis

-833

Point Spread

San Francisco +11.5

-102

Saint Louis -11.5

-120

Total Points

Under 153.5

-110

Over 153.5

-110

As an alternative to the game lines, check out the player prop bets that are available. It’s especially great if you have a view when it comes to Turnovers, Steals, Blocks and Points, while there are lots of other options.

It’s possible to use stats to your advantage when it comes to college basketball micro betting, especially if you’re predicting outcomes such as the Next Field Goal. Check out the live player, score and team props to see if you can find an angle.

Latest regular season and playoff games stats.

San Francisco Stats

Saint Louis Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 9 wins and 1 defeat in the last 10 home games

Point Spread

• +10.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +10.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -10.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -10.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 142.50 pts in the previous 10 games
• Game Totals on the Road: An average of 146.40 pts in the previous 10 games on the road
• Over 153.5: Has not been covered in any of the previous 10 games
• Over 153.5 on the Road: Covered in 2 of the previous 10 games on the road
• Team Totals: Have scored an average of 74.60 pts and allowed 67.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 72.90 pts and allowed 73.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 163.10 pts in the previous 10 games
• Game Totals at Home: An average of 162.50 pts in the previous 10 home games
• Over 153.5: Covered in 7 of the previous 10 games
• Over 153.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 90.20 pts and allowed 72.90 pts in the last 10 games
• Team Totals at Home: Have scored an average of 90.60 pts and allowed 71.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic 10	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Louis	26-3	2586	1992	594	19-1	7-2	1W
VCU	22-7	2417	2111	306	15-3	7-4	1W
George Mason	22-7	2139	1970	169	16-2	6-5	1W
Dayton	20-9	2201	2046	155	15-3	5-6	5W
Saint Joseph's	19-10	2127	2028	99	14-3	5-7	4W
Davidson	18-11	2110	1963	147	11-7	7-4	2W
Duquesne	16-13	2320	2208	112	11-7	5-6	3L
George Washington	16-13	2408	2133	275	12-5	4-8	1L
Fordham	16-13	2028	1893	135	11-7	5-6	1L
Rhode Island	15-14	2062	2002	60	9-7	6-7	3L
Richmond	15-14	2251	2147	104	11-6	4-8	1L
St. Bonaventure	15-14	2226	2168	58	10-6	5-8	1L
La Salle	8-21	1905	2099	-194	6-8	2-13	2L
Loyola Chicago	7-22	1937	2228	-291	5-12	2-10	1W

West Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Gonzaga	28-3	2665	2054	611	18-0	10-3	1L
Saint Mary's	27-4	2431	1990	441	18-0	9-4	8W
Santa Clara	24-7	2597	2245	352	15-3	9-4	1W
Seattle	19-12	2257	2094	163	14-5	5-7	3W
Pacific	17-14	2270	2137	133	12-3	5-11	4L
Oregon State	16-15	2213	2305	-92	12-8	4-7	1L
San Francisco	16-15	2305	2271	34	10-6	6-9	1W
Loyola Marymount	15-16	2314	2240	74	10-9	5-7	1L
Portland	12-18	2210	2364	-154	11-6	1-12	1W
Washington State	11-19	2367	2421	-54	9-7	2-12	3L
San Diego	11-20	2336	2450	-114	9-8	2-12	4L
Pepperdine	9-22	2244	2469	-225	7-10	2-12	1W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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