Santa Clara vs Saint Mary's Prediction, Picks & Odds | 25 Feb 2026

College Basketball Betting Preview: Santa Clara vs Saint Mary's

The Santa Clara Broncos battle the Saint Mary's Gaels, with tip-off scheduled for 23:00 on Wednesday, February 25.

Our best wager is that Saint Mary's are going to cover a generous -4.5 on the spread. You can get -120 that there’s a bigger margin of victory against Santa Clara.

Santa Clara Broncos triumphed in their previous game. It was on the road where San Francisco Dons were beaten 94-73.

Saint Mary's Gaels won their last game 83-67. This was a road victory against Washington State Cougars.

Head-to-Head Statistics

Santa Clara triumphed 62-54 when they last played Saint Mary's. The past 10 clashes between these teams have seen eight Saint Mary's wins.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Saint Mary's	25-4	2275	1864	411	16-0	9-4	6W
Santa Clara	23-6	2437	2087	350	14-3	9-3	1W

View Full Standings

Santa Clara vs Saint Mary's Prediction & Picks

This expert Santa Clara vs Saint Mary's betting breakdown features our match prediction, a correct score pick and a carefully constructed bet builder to guide your wagers.

Game Prediction

We’re excited to see Saint Mary's at -4.5 on the spread in this college matchup. We think it’s a great number for the betting favorites to cover at odds of -120.

Incoming team news often impacts the betting lines and odds in significant ways. Our college hoops handicappers factor this in alongside recent form, while key stats are also carefully weighed to strengthen each basketball pick.

Key Santa Clara vs Saint Mary's stats:

• The -4.5 line has been covered by Saint Mary's in 16 consecutive games at home.
• The -4.5 line has been covered by Saint Mary's in 18 of their last 20 games at home.
• The -4.5 line has been covered by Saint Mary's in 6 of their last 10 games against Santa Clara.

Saint Mary's -4.5 Probability

The best sportsbooks are estimating that there is a 54.6% chance of this pick winning. In the opinion of our analysts, there’s actually a probability of success closer to 60%. It’s the reason why we are recommending this college basketball bet.

There’s the chance to sell points and that means moving the line until you’re happy with the wager. It means a riskier bet but a bigger return on the odds available.

Before your next bet, explore our betting offers guide filled with top bonuses, the latest promotions, and free bet deals.

Our Game Prediction

Saint Mary's -4.5 @ -120 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Feb 25, 03:03). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Santa Clara 70 - 78 Saint Mary's

Should you want to go for a selection at massive odds, head to the correct score lines where Saint Mary's can be backed speculatively to achieve a 78-70 victory.

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Santa Clara vs Saint Mary's Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Saint Mary's have the shortest price to win this college game, with the sportsbooks giving them a 71% probability due to their -244 Moneyline betting odds. For those wanting to back Santa Clara, you will find +198 about the underdogs.

The spread is currently 4.5, with the total points line at 152.5. Basketball bettors love the chance to get an alternative angle by going for a Total wager. If you’re going for Under 152.5, this outcome can be backed at -110.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Santa Clara

+198

Saint Mary's

-244

Point Spread

Santa Clara +4.5

-102

Saint Mary's -4.5

-120

Total Points

Under 152.5

-110

Over 152.5

-110

Should you be more interested in a specific individual who is competing, check out the gambling sites’ prop bets where you can pick out player lines that focus on performance rather than the game result.

Micro betting provides a rollercoaster ride for college basketball bettors. It can be great to enjoy the live lines, with the opportunity to bet on the Next Field Goal. Watch the live action before deciding which way to go.

Latest regular season and playoff games stats.

Santa Clara Stats

Saint Mary's Stats

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 8 wins and 2 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +4.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +4.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -4.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -4.5 Betting Line at Home: Have covered the spread in the last 10 home games

Total Points

• Game Totals: An average of 158.40 pts in the previous 10 games
• Game Totals on the Road: An average of 165.60 pts in the previous 10 games on the road
• Over 152.5: Covered in 8 of the previous 10 games
• Over 152.5 on the Road: Covered in 9 of the previous 10 games on the road
• Team Totals: Have scored an average of 85.50 pts and allowed 72.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 87.80 pts and allowed 77.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 138.30 pts in the previous 10 games
• Game Totals at Home: An average of 146.10 pts in the previous 10 home games
• Over 152.5: Has not been covered in any of the previous 10 games
• Over 152.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 75.60 pts and allowed 62.70 pts in the last 10 games
• Team Totals at Home: Have scored an average of 82.20 pts and allowed 63.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

West Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Gonzaga	27-2	2517	1936	581	17-0	10-2	5W
Saint Mary's	25-4	2275	1864	411	16-0	9-4	6W
Santa Clara	23-6	2437	2087	350	14-3	9-3	1W
Seattle	17-12	2099	1948	151	14-5	3-7	1W
Pacific	17-13	2209	2065	144	12-2	5-11	3L
Oregon State	15-14	2049	2130	-81	11-8	4-6	1W
San Francisco	15-15	2233	2210	23	10-6	5-9	2L
Loyola Marymount	14-15	2181	2103	78	9-8	5-7	1W
Portland	11-17	2075	2201	-126	10-6	1-11	3L
Washington State	11-17	2222	2266	-44	9-7	2-10	1L
San Diego	11-18	2180	2271	-91	9-8	2-10	2L
Pepperdine	8-21	2076	2303	-227	6-9	2-12	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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