Seton Hall vs DePaul Prediction, Picks & Odds | 24 Jan 2026

College Basketball Betting Preview: Seton Hall vs DePaul

The Seton Hall Pirates square off against the DePaul Blue Demons, with tip-off scheduled for 17:00 on Saturday, January 24.

We think a wager on the totals provides value after finding that the line is set at a generous 133.5 points. Expect Seton Hall and DePaul to surpass this number at -115.

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Seton Hall Pirates suffered a defeat in their previous game. A 65-60 scoreline occurred on the road against St. John's Red Storm.

DePaul Blue Demons suffered a defeat in their last game. A 87-80 scoreline occurred on the road against Butler Bulldogs.

Head-to-Head Statistics

It was DePaul who came out on top when they last played Seton Hall. A 74-57 win was recorded. The past 10 clashes between these teams have seen seven Seton Hall wins.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Seton Hall	14-5	1371	1214	157	8-3	6-2	3L
DePaul	11-8	1399	1329	70	10-4	1-4	1L

View Full Standings

Seton Hall vs DePaul Prediction & Picks

Get ahead of the game with our Seton Hall vs DePaul betting rundown, featuring our trusted match prediction, most likely correct score outcome and a fully loaded bet builder.

Game Prediction

We think the best betting angle can be found with the totals for this college contest. Our pick is that there will be Over 133.5 points and that is available at -115.

The college hoops handicappers at Sportsgambler.com always keep close tabs on team news as it develops. We also rely on recent form and key stats to help shape our basketball picks and guide the final call.

Key Seton Hall vs DePaul stats:

• The 133.5 line has been covered in 4 of the last 5 Seton Hall games on the road.
• The 133.5 line has been covered in 7 of the last 10 Seton Hall games on the road.
• The 133.5 line has been covered in 8 of the last 10 DePaul games at home.
• The 133.5 line has been covered in 15 of the last 20 DePaul games.
• The 133.5 line has been covered in the last 2 DePaul games.

Over 133.5 Probability

Based on the odds from the top betting sites, there’s a 53.5% likelihood of our pick delivering a return. Taking all factors into consideration, our experts think there’s a stronger chance of success and estimate the probability to be closer to 60%. It’s why we think it’s worth placing this college basketball bet.

There are ways to get bigger odds by betting Over on the Totals. Bettors often look to move the line so they can land a more profitable return if the selection wins.

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Our Game Prediction

Over 133.5 Points @ -115 Bet Now

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Correct Score Prediction

Seton Hall 68 - 70 DePaul

We’ll roll the dice and go for the Blue Demons to register a 70-68 victory. We don’t think that there will be too much between the teams and we’re happy to take the massive odds.

Seton Hall vs DePaul Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The Seton Hall odds have been priced up by the sportsbooks and they are -156 betting favorites to land victory in this college game which means a 61% chance of winning. DePaul are the underdogs at +130 and they’re regarded as least likely to win.

The current spread is 2.5 and the total points line is 133.5. There are many ways to bet on basketball including the Totals. If you’re wanting to back Over 133.5, the odds are -115.

Consider every angle when placing your college hoops bets. The top basketball betting sites offer a huge selection of game lines and team props, and it’s all about finding a wager that fits your prediction of the game.

Moneyline

Seton Hall

-156

DePaul

+130

Point Spread

Seton Hall -2.5

-110

DePaul +2.5

-110

Total Points

Under 133.5

-105

Over 133.5

-115

We’re fond of player props as an alternative to betting on the game result. The gambling sites will have Points, Assists, Three-Pointers, Rebounds and Steals among the choices and you can take a particular view.

Micro betting provides a rollercoaster ride for college basketball bettors. It can be great to enjoy the live lines, with the opportunity to bet on the Next Field Goal. Watch the live action before deciding which way to go.

Latest regular season and playoff games stats.

Seton Hall Stats

DePaul Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• -2.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -2.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• +2.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +2.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games

Total Points

• Game Totals: An average of 135.00 pts in the previous 10 games
• Game Totals on the Road: An average of 141.60 pts in the previous 10 games on the road
• Over 133.5: Covered in 6 of the previous 10 games
• Over 133.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 68.80 pts and allowed 66.20 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 71.10 pts and allowed 70.50 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 139.10 pts in the previous 10 games
• Game Totals at Home: An average of 145.90 pts in the previous 10 home games
• Over 133.5: Covered in 6 of the previous 10 games
• Over 133.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 70.10 pts and allowed 69.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 77.00 pts and allowed 68.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big East	Overall	PF	PA	N. Pts	Home	Away	Strk
UConn	19-1	1566	1269	297	11-1	8-0	15W
St. John's	15-5	1701	1453	248	9-3	6-2	6W
Villanova	15-5	1548	1379	169	10-2	5-3	1L
Seton Hall	14-5	1371	1214	157	8-3	6-2	3L
Butler	13-7	1671	1518	153	12-3	1-4	3W
Creighton	12-8	1580	1487	93	10-2	2-6	1W
DePaul	11-8	1399	1329	70	10-4	1-4	1L
Xavier	11-9	1570	1544	26	10-5	1-4	2L
Georgetown	10-10	1511	1478	33	7-5	3-5	1W
Providence	9-11	1783	1721	62	7-5	2-6	2L
Marquette	7-14	1593	1661	-68	7-6	0-8	1L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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