SIU Edwardsville vs Eastern Illinois Prediction, Picks & Odds | 18 Dec 2025

College Basketball Betting Preview: SIU Edwardsville vs Eastern Illinois

The SIU Edwardsville Cougars square off against the Eastern Illinois Panthers, with tip-off scheduled for 18:30 on Thursday, December 18.

Place a wager on SIUE with a -6.5 spread when they face Eastern Illinois. We’re confident they can cover this generous betting line at odds of -115.

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SIU Edwardsville Cougars previous game saw them claim a 97-54 home win over Eureka Red Devils.

Eastern Illinois Panthers suffered a defeat in their last game. A 78-53 scoreline occurred on the road against Iowa State Cyclones.

Head-to-Head Statistics

The scoreline was 66-41 in favor of SIUE when they last played Eastern Illinois. SIUE have enjoyed three consecutive wins against Eastern Illinois. They’ve landed 7 victories from the past 10 head-to-head meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
SIU Edwardsville	7-4	861	727	134	3-2	4-2	1W
Eastern Illinois	2-8	609	768	-159	2-2	0-6	5L

View Full Standings

SIU Edwardsville vs Eastern Illinois Prediction & Picks

Head into SIU Edwardsville vs Eastern Illinois with expert betting insights, including our main match prediction, best correct score pick and a value-driven bet builder. Dive into each section below for more.

Game Prediction

Our pick is that SIUE will gain the upper hand in this college contest. This leads us to backing them against the spread at -115, with the -6.5 line offering lots of appeal.

The college hoops handicappers at Sportsgambler.com always keep close tabs on team news as it develops. We also rely on recent form and key stats to help shape our basketball picks and guide the final call.

Key SIU Edwardsville vs Eastern Illinois stats:

• The -6.5 line has been covered by SIUE in 4 of their last 5 games.
• The -6.5 line has been covered by SIUE in 2 consecutive games on the road.
• The +6.5 line hasn’t been covered by Eastern Illinois in 5 consecutive games.
• The +6.5 line hasn’t been covered by Eastern Illinois in 7 of their last 10 games.
• The +6.5 line hasn’t been covered by Eastern Illinois in 6 of their last 10 games against SIUE.

SIUE -6.5 Probability

Based on the odds from the top betting sites, there’s a 53.5% likelihood of our pick delivering a return. In our opinion, there’s actually a probability of success closer to 60%. That means we’re regarding it as a value bet.

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Our Game Prediction

SIUE -6.5 @ -115 Bet Now

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Correct Score Prediction

SIUE 75 - 66 Eastern Illinois

There are a range of correct score lines to choose from and we’re taking a chance on the Cougars to record a 75-66 victory. There’s a huge return if we get this right.

SIU Edwardsville vs Eastern Illinois Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The sportsbooks are taking no chances with their Moneyline odds of +225 about Eastern Illinois which reflects they have a 31% chance of winning this college game. SIU Edwardsville are trading at bigger odds than their opponents and they can be backed at -294.

The spread is currently 6.5, with the total points line at 135.5. A Total bet is always available and can often provide value selections. If you want to back Over 135.5, it’s -116.

You’ll find a broad selection of team props and game lines for most college contests, with the best basketball betting sites offering plenty of options. Be sure to review both the pre-game and in-game markets before placing your bets.

Moneyline

SIUE

-294

Eastern Illinois

+225

Point Spread

SIUE -6.5

-114

Eastern Illinois +6.5

-106

Total Points

Under 135.5

-108

Over 135.5

-116

If you have a view on Total Points, Three-Pointers, Assists, Double-Doubles or Triple-Doubles, then the player prop betting could be up your street. It’s a great way of wagering on individual performance.

You don’t have to wait for the final outcome when it comes to college basketball micro betting. Instead, there’s the opportunity to wager on live lines which tend to be settled in a shorter space of time and the in-game odds are always changing.

Latest regular season and playoff games stats.

SIU Edwardsville Stats

Eastern Illinois Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 games on the road

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 home games

Point Spread

• -6.5 Betting Line: Have covered the spread in 5 of the last 10 games
• -6.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +6.5 Betting Line: Have covered the spread in 3 of the last 10 games
• +6.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games

Total Points

• Game Totals: An average of 141.90 pts in the previous 10 games
• Game Totals on the Road: An average of 137.30 pts in the previous 10 games on the road
• Over 135.5: Covered in 7 of the previous 10 games
• Over 135.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 74.20 pts and allowed 67.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 68.20 pts and allowed 69.10 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 137.70 pts in the previous 10 games
• Game Totals at Home: An average of 129.70 pts in the previous 10 home games
• Over 135.5: Covered in 5 of the previous 10 games
• Over 135.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 60.90 pts and allowed 76.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 64.70 pts and allowed 65.00 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Ohio Valley	Overall	PF	PA	N. Pts	Home	Away	Strk
UT Martin	8-3	835	720	115	5-0	3-3	1W
SIU Edwardsville	7-4	861	727	134	3-2	4-2	1W
Lindenwood	6-4	814	731	83	3-0	3-4	4W
Tennessee State	6-4	795	751	44	3-0	3-4	1W
Tennessee Tech	5-6	889	857	32	3-1	2-5	2W
Southeast Missouri	5-6	863	832	31	3-2	2-4	3W
Morehead State	4-7	839	889	-50	3-0	1-7	1W
Southern Indiana	3-7	737	777	-40	2-1	1-6	2L
Western Illinois	3-7	672	772	-100	2-2	1-5	1W
Eastern Illinois	2-8	609	768	-159	2-2	0-6	5L
Little Rock	2-9	717	877	-160	1-1	1-8	7L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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