Southern Illinois vs Murray State Prediction, Picks & Odds | 29 Dec 2025

College Basketball Betting Preview: Southern Illinois vs Murray State

The Southern Illinois Salukis battle the Murray State Racers, with tip-off scheduled for 19:00 on Monday, December 29.

We’re going for a modest total when Southern Illinois and Murray State take to the court. Under 165.5 points could be on the money and our prediction is currently available at -105.

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Southern Illinois Salukis were beaten in their previous game and this was on the road. Bradley Braves claimed a 73-69 win.

Murray State Racers triumphed in their last game. It was on the road where Valparaiso Beacons were beaten 85-79.

Head-to-Head Statistics

Murray State have beaten Southern Illinois in their last two matchups. On the road, they won 74-64 and followed up with a 62-60 home win. The previous 9 H2H meetings have involved Southern Illinois winning five times.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Murray State	10-3	1161	1015	146	8-0	2-3	6W
Southern Illinois	6-7	1024	956	68	4-2	2-5	3L

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Southern Illinois vs Murray State Prediction & Picks

Gear up for Southern Illinois vs Murray State with our betting guide, featuring an expert match prediction, scoreline advice and a hand-picked bet builder. Explore each section below for detailed insights.

Game Prediction

The Unders looks the way to go for this college matchup. The line looks too high at 165.5 and odds of -105 could favor bettors who go below that total.

Our basketball picks are built after tracking the latest team news and reviewing recent form. We also dive into stats, which often serve as a solid barometer for how the college hoops action might unfold.

Key Southern Illinois vs Murray State stats:

• The 165.5 line hasn’t been covered in 7 of the last 10 Southern Illinois games.
• The 165.5 line hasn’t been covered in 13 of the last 20 Southern Illinois games on the road.
• The 165.5 line hasn’t been covered in the last 2 Southern Illinois games.
• The 165.5 line hasn’t been covered in 4 of the last 5 Murray State games.
• The 165.5 line hasn’t been covered in 16 of the last 20 Murray State games at home.
• The 165.5 line hasn’t been covered in the last 3 Murray State games at home.
• The 165.5 line hasn’t been covered in the last 9 games between these teams.

Under 165.5 Probability

The top sportsbooks imply that our pick has a 51.3% prospect of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and estimate the probability to be closer to 60%. It’s the reason why we are recommending this college basketball bet.

Those bettors wanting more bang for their buck can move the Total line as they see fit. You can bet Under a certain points level in order to get the bigger odds.

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Our Game Prediction

Under 165.5 Points @ -105 Bet Now

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Correct Score Prediction

Southern Illinois 75 - 86 Murray State

You don’t need a big stake to enjoy a huge payout by getting this correct score right. We’re going for Murray State to achieve a 86-75 victory and hopefully this goes close.

Southern Illinois vs Murray State Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

With a 74% chance of securing victory, Murray State are favorites for this college game and the sportsbooks have them at betting odds of -278. Southern Illinois are trading at bigger odds than their opponents and they can be backed at +220.

The current spread is 6.5 and the total points line is 165.5. Basketball fans regularly enjoy the opportunity to bet on the Totals. If you’re going for Under 165.5, this outcome can be backed at -105.

College basketball bettors are spoilt for choice thanks to the huge selection of game lines and team props which are available for most matchups on the coupon. Head to the top betting apps and find the best value picks.

Moneyline

Southern Illinois

+220

Murray State

-278

Point Spread

Southern Illinois +6.5

-110

Murray State -6.5

-110

Total Points

Under 165.5

-105

Over 165.5

-115

As an alternative to the game lines and team props, check out the player props that are available. These can be a great alternative if you want to focus on a player’s performance. The best gambling sites will provide lots of options.

Among the various options for wagering on college basketball, you will find that micro betting is provided. It focuses on short-term in-game outcomes such as Next Field Goal, where you select if the shot will be a two or three-pointer.

Latest regular season and playoff games stats.

Southern Illinois Stats

Murray State Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +6.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +6.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -6.5 Betting Line: Have covered the spread in 6 of the last 10 games
• -6.5 Betting Line at Home: Have covered the spread in 9 of the last 10 home games

Total Points

• Game Totals: An average of 150.90 pts in the previous 10 games
• Game Totals on the Road: An average of 152.00 pts in the previous 10 games on the road
• Over 165.5: Covered in 3 of the previous 10 games
• Over 165.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 75.90 pts and allowed 75.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 73.20 pts and allowed 78.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 165.30 pts in the previous 10 games
• Game Totals at Home: An average of 158.10 pts in the previous 10 home games
• Over 165.5: Covered in 4 of the previous 10 games
• Over 165.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 87.70 pts and allowed 77.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 88.20 pts and allowed 69.90 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Missouri Valley	Overall	PF	PA	N. Pts	Home	Away	Strk
Belmont	12-1	1110	887	223	7-1	5-0	4W
Illinois State	10-3	1053	875	178	8-1	2-2	2W
Murray State	10-3	1161	1015	146	8-0	2-3	6W
Northern Iowa	9-3	854	697	157	6-1	3-2	1L
Bradley	9-4	1020	904	116	8-2	1-2	6W
Drake	7-6	1028	899	129	4-5	3-1	1W
Indiana State	7-6	993	952	41	5-1	2-5	2L
Southern Illinois	6-7	1024	956	68	4-2	2-5	3L
Valparaiso	5-6	782	796	-14	4-3	1-3	4L
UIC	4-8	909	894	15	3-3	1-5	6L
Evansville	4-9	902	947	-45	3-6	1-3	4L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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