Southern Miss vs LSU Prediction, Picks & Odds | 29 Dec 2025

College Basketball Betting Preview: Southern Miss vs LSU

The Southern Miss Golden Eagles go up against the LSU Tigers, with tip-off scheduled for 20:00 on Monday, December 29.

LSU can finish well clear of Southern Miss and that means we’re going for them against the spread. There is -120 on offer that the favorites are able to cover a -18.5 line.

Backing our spread pick? Check out our full review of BetMGM and unlock today’s best promo code to make your wager go further.

Southern Miss Golden Eagles were beaten 93-86 in their previous game, being turned over at home to Arkansas State Red Wolves.

LSU Tigers last game saw them claim a 104-90 home win over Prairie View A&M Panthers.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
LSU	11-1	1067	861	206	8-1	3-0	3W
Southern Miss	7-6	994	943	51	6-1	1-5	1L

View Full Standings

Southern Miss vs LSU Prediction & Picks

Explore our best Southern Miss vs LSU picks, including a main match prediction, correct score forecast and a bet builder ready to use. Scroll down for full analysis.

Game Prediction

We’d be surprised if LSU don’t exceed a -18.5 spread in this college showdown. That is why the bet has to be the big favorites to cover the line at -120.

Our basketball predictions are always well-researched, starting with a combination of the latest college hoops team news and current form. Once we’ve got a solid read on the matchup, we layer in the key data to back it up.

Key Southern Miss vs LSU stats:

• The -18.5 line has been covered by LSU in 4 of their last 10 games at home.

LSU -18.5 Probability

If you go by the best sportsbooks, our pick has a 54.6% chance of landing a return. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. The bet can be recommended for this precise reason.

Looking for more juice from your selection? By moving the betting line, you are able to get bigger odds although you will need to take a riskier bet.

Stop! Before you bet, grab a top welcome bonus. Check out our guide for the latest betting offers available now.

Our Game Prediction

LSU -18.5 @ -120 Bet Now

BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+

Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Correct Score Prediction

Southern Miss 64 - 85 LSU

A 85-64 win for the Tigers is clearly a risky bet although this could be an exciting correct score option where there’s the chance to enjoy a huge potential return.

Southern Miss vs LSU Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

The sportsbooks are taking no chances with their Moneyline odds of -5000 about LSU which reflects they have a 98% chance of winning this college game. For those wanting to oppose the market leader, you can get +1400 about Southern Miss.

The spread is currently 18.5, with the total points line at 157.5. There are many ways to bet on basketball including the Totals. Those expecting a low total can back Under 157.5 at -105.

If you’re wagering on college basketball, we recommend heading to the top betting apps and scanning through the many game lines and team props. There’s a chance to wager pre-game and in-game.

Moneyline

Southern Miss

+1400

LSU

-5000

Point Spread

Southern Miss +18.5

-102

LSU -18.5

-120

Total Points

Under 157.5

-105

Over 157.5

-115

If you have a view on Total Points, Three-Pointers, Assists, Double-Doubles or Triple-Doubles, then the player prop betting could be up your street. It’s a great way of wagering on individual performance.

Micro betting is something that’s really popular with bettors, with college basketball fans essentially being able to wager in-game when it comes to score, player and team props. Check out the two-way lines where you can bet whether the next shot will be a Two-pointer or a Three-pointer.

Latest regular season and playoff games stats.

Southern Miss Stats

LSU Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 1 win and 9 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +18.5 Betting Line: Have covered the spread in 9 of the last 10 games
• +18.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road

Point Spread

• -18.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -18.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 146.10 pts in the previous 10 games
• Game Totals on the Road: An average of 153.60 pts in the previous 10 games on the road
• Over 156.5: Covered in 3 of the previous 10 games
• Over 156.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 74.30 pts and allowed 71.80 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 72.20 pts and allowed 81.40 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 162.10 pts in the previous 10 games
• Game Totals at Home: An average of 160.70 pts in the previous 10 home games
• Over 156.5: Covered in 6 of the previous 10 games
• Over 156.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 87.80 pts and allowed 74.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 87.40 pts and allowed 73.30 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Southeastern	Overall	PF	PA	N. Pts	Home	Away	Strk
Vanderbilt	12-0	1129	866	263	7-0	5-0	12W
Georgia	11-1	1198	862	336	9-1	2-0	5W
LSU	11-1	1067	861	206	8-1	3-0	3W
Missouri	10-3	1089	929	160	9-0	1-3	1L
Texas A&M	9-3	1140	921	219	7-1	2-2	2W
Tennessee	9-3	986	774	212	8-2	1-1	2W
Arkansas	9-3	1074	899	175	8-2	1-1	1L
Oklahoma	9-3	1043	872	171	7-0	2-3	3W
Alabama	9-3	1127	983	144	7-3	2-0	2W
Kentucky	9-4	1104	881	223	9-3	0-1	4W
Texas	9-4	1143	927	216	8-2	1-2	2W
Florida	8-4	1012	843	169	8-1	0-3	3W
South Carolina	8-4	957	820	137	8-1	0-3	1W
Auburn	8-4	1011	933	78	7-2	1-2	1L
Ole Miss	7-5	891	821	70	7-1	0-4	1L
Mississippi State	7-5	945	930	15	6-3	1-2	3W

Sun Belt	Overall	PF	PA	N. Pts	Home	Away	Strk
Arkansas State	9-4	1066	1029	37	4-0	5-4	2W
South Alabama	9-4	974	906	68	4-1	5-3	1L
Georgia Southern	10-5	1260	1182	78	7-1	3-4	7W
Troy	8-5	1138	1023	115	3-2	5-3	3W
Marshall	8-5	1039	973	66	6-1	2-4	1W
Appalachian State	8-6	1028	923	105	6-2	2-4	1L
Texas State	8-6	1032	957	75	8-2	0-4	1W
Coastal Carolina	8-6	1019	990	29	3-0	5-6	2W
Southern Miss	7-6	994	943	51	6-1	1-5	1L
James Madison	7-6	986	989	-3	6-0	1-6	2L
Old Dominion	4-10	1023	1076	-53	4-1	0-9	2L
Georgia State	4-10	965	1067	-102	3-2	1-8	2W
Louisiana	3-11	811	960	-149	2-3	1-8	2W
UL Monroe	3-11	1036	1161	-125	3-4	0-7	4L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

Top Basketball Pages