Syracuse vs Duke Prediction, Picks & Odds | 16 Feb 2026

College Basketball Betting Preview: Syracuse vs Duke

The Syracuse Orange face the Duke Blue Devils, with tip-off scheduled for 19:00 on Monday, February 16.

We really fancy the chances of Duke beating Syracuse handsomely. That is why we’re backing them at -20.5 on the spread at odds of -118.

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Syracuse Orange won their previous game, beating SMU Mustangs at home. It was a 79-78 win.

Duke Blue Devils last game saw them claim a 67-54 home win over Clemson Tigers.

Head-to-Head Statistics

The last matchup between Duke and Syracuse saw the former win. It was a 83-54 scoreline. Duke have won all of the past 10 H2H meetings.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	23-2	2056	1578	478	14-0	9-2	2W
Syracuse	15-11	1989	1876	113	12-4	3-7	2W

View Full Standings

Syracuse vs Duke Prediction & Picks

We dive into the top Syracuse vs Duke betting angles, including our main match prediction, best correct score play and a bet builder tailored for value.

Game Prediction

Duke can finish well clear in this college game and that means we’re going for them against the spread. There is -118 on offer that the favorites are able to cover a -20.5 line.

The formbook is always a smart starting point when making basketball predictions. Up-to-date college hoops team news is just as important, while the stats we provide often reveal valuable insights.

Key Syracuse vs Duke stats:

• The -20.5 line has been covered by Duke in 5 of their last 10 games at home.

Duke -20.5 Probability

Looking at the latest betting odds, our pick has a 54.1% chance of winning. Based on our in-depth research, we calculate the actual probability to be closer to 60%. The bet can be recommended for this precise reason.

Want bigger odds when it comes to your wager? Never fear, you are able to head to the sportsbooks and move the line until you’re happy with the price.

Thinking of placing a bet? Make sure to check our guide first — it’s full of the latest offers and welcome bonuses worth claiming.

Our Game Prediction

Duke -20.5 @ -118 Bet Now

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Correct Score Prediction

Syracuse 63 - 86 Duke

There are a range of correct score lines to choose from and we’re taking a chance on Duke to record a 86-63 victory. There’s a huge return if we get this right.

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Syracuse vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

You might not get rich backing Duke at -5000. However, the sportsbooks’ betting odds imply a 98% chance of winning this college game. Syracuse are the underdogs at +1600 and they’re regarded as least likely to win.

The current spread is 20.5 and the total points line is 142.5. The advantage of the Totals is that you only have to choose from one of two options. If you fancy Over 142.5, this outcome can be backed at -115.

Whether you are betting pre-game or in-game, you can feast on a wide range of team props and game lines at the top basketball sportsbooks. The selections are practically endless, and it’s fantastic to have so many options.

Moneyline

Syracuse

+1600

Duke

-5000

Point Spread

Syracuse +20.5

-110

Duke -20.5

-110

Total Points

Under 142.5

-105

Over 142.5

-115

The gambling sites will have player props available for each game. Check out the various betting odds and take a view on whether a player’s Total Points, Three-Pointers, Blocks or Steals will hit over or under a certain line.

Micro betting is an exciting way to wager on college basketball. There are many live lines and it’s a simple case of predicting what is going to happen. Next Field Goal, where you select if the shot will be a two or three-pointer are among the options.

Latest regular season and playoff games stats.

Syracuse Stats

Duke Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 games on the road

Moneyline

• 9 wins and 1 defeat in the last 10 games
• 10 wins and 0 defeats in the last 10 home games

Point Spread

• +20.5 Betting Line: Have covered the spread in the last 10 games
• +20.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road

Point Spread

• -20.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -20.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games

Total Points

• Game Totals: An average of 161.80 pts in the previous 10 games
• Game Totals on the Road: An average of 148.60 pts in the previous 10 games on the road
• Over 143.5: Covered in 9 of the previous 10 games
• Over 143.5 on the Road: Covered in 7 of the previous 10 games on the road
• Team Totals: Have scored an average of 79.30 pts and allowed 82.50 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 72.00 pts and allowed 76.60 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 133.80 pts in the previous 10 games
• Game Totals at Home: An average of 144.60 pts in the previous 10 home games
• Over 143.5: Covered in 2 of the previous 10 games
• Over 143.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 75.00 pts and allowed 58.80 pts in the last 10 games
• Team Totals at Home: Have scored an average of 83.10 pts and allowed 61.50 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	23-2	2056	1578	478	14-0	9-2	2W
Virginia	22-3	2035	1685	350	13-1	9-2	6W
Miami	20-5	2089	1752	337	13-3	7-2	3W
North Carolina	20-5	2045	1761	284	16-0	4-5	1W
Clemson	20-6	1945	1682	263	13-2	7-4	2L
Louisville	19-6	2172	1773	399	13-2	6-4	5W
NC State	18-8	2209	1934	275	11-5	7-3	2L
California	18-8	2053	1897	156	15-3	3-5	1W
SMU	17-8	2155	1939	216	14-2	3-6	1L
Virginia Tech	17-9	2058	1943	115	13-3	4-6	1L
Stanford	16-10	1961	1886	75	10-6	6-4	1L
Syracuse	15-11	1989	1876	113	12-4	3-7	2W
Wake Forest	13-12	1992	1925	67	9-6	4-6	2W
Florida State	12-13	2009	1960	49	9-7	3-6	1W
Notre Dame	12-14	1941	1909	32	10-5	2-9	1W
Georgia Tech	11-15	1937	1984	-47	10-7	1-8	7L
Boston College	9-16	1686	1733	-47	8-10	1-6	6L
Pittsburgh	9-17	1818	1866	-48	7-9	2-8	5L

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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