Virginia Tech vs Syracuse Prediction, Picks & Odds | 21 Jan 2026

College Basketball Betting Preview: Virginia Tech vs Syracuse

The Virginia Tech face the Syracuse Orange, with tip-off scheduled for 21:00 on Wednesday, January 21.

We’re confident of backing Syracuse to cover the -3.5 spread when they face Virginia Tech. This is a more than generous line and the favorites look a value bet at odds of -110.

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Virginia Tech claimed a victory in their previous game. A 89-76 home win occurred against Notre Dame Fighting Irish.

Syracuse Orange were beaten last game and this was on the road. Boston College Eagles claimed a 81-73 win.

Head-to-Head Statistics

The last head-to-head saw Virginia Tech claim a 101-95 (OT) win over Syracuse. In the previous 10 games between the teams, they have won five apiece.

NCAAB	Overall	PF	PA	N. Pts	Home	Away	Strk
Virginia Tech	14-5	1564	1407	157	12-1	2-4	1W
Syracuse	12-6	1363	1218	145	9-2	3-4	1L

View Full Standings

Virginia Tech vs Syracuse Prediction & Picks

Get ahead of the game with our Virginia Tech vs Syracuse betting rundown, featuring our trusted match prediction, most likely correct score outcome and a fully loaded bet builder.

Game Prediction

Syracuse at -3.5 could be the best bet to have on the spread. Odds of -110 are available and our pick would mean a solid win for the favorites in this college showdown.

The handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our basketball predictions. We combine this insight with up-to-date college hoops stats for sharper picks.

Key Virginia Tech vs Syracuse stats:

• The -3.5 line has been covered by Syracuse in 4 of their last 5 games at home.
• The -3.5 line has been covered by Syracuse in 7 of their last 10 games.

Syracuse -3.5 Probability

The top sportsbooks make it a 52.4% chance that our pick is settled as a winner. In the opinion of our analysts, there’s actually a probability of success closer to 60%. It’s the reason why we are recommending this college basketball bet.

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Our Game Prediction

Syracuse -3.5 @ -110 Bet Now

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Correct Score Prediction

Virginia Tech 74 - 82 Syracuse

There’s the chance to land huge betting odds when it comes to Syracuse winning on the correct score lines. We’ll try a 82-74 victory in their favor and this should be in the right ball park.

Virginia Tech vs Syracuse Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

With a 66% chance of securing victory, Syracuse are favorites for this college game and the sportsbooks have them at betting odds of -192. If you’re looking for an alternative angle, Virginia Tech are trading at +158.

The spread is currently 3.5, with the total points line at 151.5. The Totals offers basketball fans an alternative way of getting involved. If you're keen on Over 151.5, this selection is available at -110.

If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.

Moneyline

Virginia Tech

+158

Syracuse

-192

Point Spread

Virginia Tech +3.5

-110

Syracuse -3.5

-110

Total Points

Under 151.5

-110

Over 151.5

-110

The gambling sites also allow you to place player prop bets such as Points, Assists, Steals and Rebounds. This means you can focus on an individual player’s performance rather than wager on the actual outcome of the game in question.

It’s good to consider all wagering options when it comes to college basketball and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether the next shot will be a Two or a Three-pointer.

Latest regular season and playoff games stats.

Virginia Tech Stats

Syracuse Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• +3.5 Betting Line: Have covered the spread in the last 10 games
• +3.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -3.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -3.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 155.00 pts in the previous 10 games
• Game Totals on the Road: An average of 138.70 pts in the previous 10 games on the road
• Over 151.5: Covered in 7 of the previous 10 games
• Over 151.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 81.70 pts and allowed 73.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 66.90 pts and allowed 71.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 147.80 pts in the previous 10 games
• Game Totals at Home: An average of 141.40 pts in the previous 10 home games
• Over 151.5: Covered in 5 of the previous 10 games
• Over 151.5 at Home: Covered in 2 of the previous 10 home games
• Team Totals: Have scored an average of 77.70 pts and allowed 70.10 pts in the last 10 games
• Team Totals at Home: Have scored an average of 76.20 pts and allowed 65.20 pts in the last 10 home games

NCAAB Table Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Atlantic Coast	Overall	PF	PA	N. Pts	Home	Away	Strk
Duke	17-1	1539	1171	368	10-0	7-1	6W
Virginia	16-2	1512	1207	305	11-0	5-2	5W
Clemson	16-4	1542	1305	237	12-1	4-3	1L
Miami	15-4	1614	1310	304	11-2	4-2	2L
North Carolina	14-4	1475	1252	223	12-0	2-4	2L
SMU	14-5	1662	1460	202	12-1	2-4	1W
Virginia Tech	14-5	1564	1407	157	12-1	2-4	1W
Stanford	14-5	1453	1371	82	9-4	5-1	1L
California	14-5	1497	1339	158	14-2	0-3	1W
Louisville	13-5	1583	1252	331	9-2	4-3	1W
NC State	13-6	1625	1365	260	9-4	4-2	1W
Syracuse	12-6	1363	1218	145	9-2	3-4	1L
Wake Forest	11-8	1538	1441	97	8-4	3-4	1L
Georgia Tech	11-8	1436	1388	48	10-4	1-4	1W
Notre Dame	10-8	1321	1247	74	8-3	2-5	4L
Pittsburgh	8-10	1319	1279	40	6-6	2-4	1L
Boston College	8-10	1235	1233	2	7-6	1-4	1W
Florida State	8-11	1546	1527	19	7-6	1-5	1W

• Overall = Overall Wins-Losses
• PF = Total Points For
• PA = Total Points Against
• N. Pts = Point Differential
• Home = Home Record
• Away = Away Record
• Strk = Current Streak

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